{"id":"https://openalex.org/W7203795000","doi":"https://doi.org/10.1111/all.70466","title":"Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non\u2010Irritative Concentrations","display_name":"Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non\u2010Irritative Concentrations","publication_year":2026,"publication_date":"2026-08-19","ids":{"openalex":"https://openalex.org/W7203795000","doi":"https://doi.org/10.1111/all.70466","pmid":"https://pubmed.ncbi.nlm.nih.gov/42618976"},"language":"en","primary_location":{"id":"doi:10.1111/all.70466","doi":"https://doi.org/10.1111/all.70466","is_oa":true,"landing_page_url":"https://doi.org/10.1111/all.70466","pdf_url":null,"source":{"id":"https://openalex.org/S68090385","display_name":"Allergy","issn_l":"0105-4538","issn":["0105-4538","1398-9995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Allergy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1111/all.70466","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042448793","display_name":"Annick M. Barbaud","orcid":"https://orcid.org/0000-0001-8889-1589","observed_orcids":["https://orcid.org/0000-0001-8889-1589"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210133907","display_name":"Institut Pierre Louis d\u2018\u00c9pid\u00e9miologie et de Sant\u00e9 Publique","ror":"https://ror.org/02qqh1125","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907"]},{"id":"https://openalex.org/I4210166768","display_name":"H\u00f4pital Tenon","ror":"https://ror.org/05h5v3c50","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210166768"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Annick Barbaud","raw_affiliation_strings":["D\u00e9partement de Dermatologie et Allergologie INSERM, Institut Pierre Louis d'Epid\u00e9miologie et de Sant\u00e9 Publique, AP\u2010HP, Sorbonne Universit\u00e9, H\u00f4pital Tenon  Paris France"],"raw_orcid":"https://orcid.org/0000-0001-8889-1589","affiliations":[{"raw_affiliation_string":"D\u00e9partement de Dermatologie et Allergologie INSERM, Institut Pierre Louis d'Epid\u00e9miologie et de Sant\u00e9 Publique, AP\u2010HP, Sorbonne Universit\u00e9, H\u00f4pital Tenon  Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210133907","https://openalex.org/I4210166768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072512653","display_name":"Lene H. Garvey","orcid":"https://orcid.org/0000-0002-7777-4501","observed_orcids":["https://orcid.org/0000-0002-7777-4501"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Lene Heise Garvey","raw_affiliation_strings":["Allergy Clinic, Department of Dermatology and Allergy Copenhagen University Hospital\u2010Herlev and Gentofte  Copenhagen Denmark","Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"],"raw_orcid":"https://orcid.org/0000-0002-7777-4501","affiliations":[{"raw_affiliation_string":"Allergy Clinic, Department of Dermatology and Allergy Copenhagen University Hospital\u2010Herlev and Gentofte  Copenhagen Denmark","institution_ids":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"raw_affiliation_string":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark","institution_ids":["https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080985934","display_name":"Elizabeth Jane Phillips","orcid":"https://orcid.org/0000-0002-7623-3383","observed_orcids":["https://orcid.org/0000-0002-7623-3383"]},"institutions":[{"id":"https://openalex.org/I176790772","display_name":"Murdoch University","ror":"https://ror.org/00r4sry34","country_code":"AU","type":"education","lineage":["https://openalex.org/I176790772"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Elizabeth Phillips","raw_affiliation_strings":["Department of Medicine Center for Drug Safety and Immunology, Vanderbilt University Medical Center  Nashville Tennessee USA","Institute for Immunology and Infectious Diseases Murdoch University  Murdoch Western Australia Australia"],"raw_orcid":"https://orcid.org/0000-0002-7623-3383","affiliations":[{"raw_affiliation_string":"Department of Medicine Center for Drug Safety and Immunology, Vanderbilt University Medical Center  Nashville Tennessee USA","institution_ids":["https://openalex.org/I901861585"]},{"raw_affiliation_string":"Institute for Immunology and Infectious Diseases Murdoch University  Murdoch Western Australia Australia","institution_ids":["https://openalex.org/I176790772"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027137275","display_name":"Michael R. Ardern\u2010Jones","orcid":"https://orcid.org/0000-0003-1466-2016","observed_orcids":["https://orcid.org/0000-0003-1466-2016"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Ardern\u2010Jones","raw_affiliation_strings":["Clinical Experimental Sciences, Faculty of Medicine University of Southampton  Southampton UK","Department of Dermatology University Hospitals NHS Foundation Trust  Southampton UK"],"raw_orcid":"https://orcid.org/0000-0003-1466-2016","affiliations":[{"raw_affiliation_string":"Clinical Experimental Sciences, Faculty of Medicine University of Southampton  Southampton UK","institution_ids":["https://openalex.org/I43439940"]},{"raw_affiliation_string":"Department of Dermatology University Hospitals NHS Foundation Trust  Southampton UK","institution_ids":["https://openalex.org/I2802965805"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054370889","display_name":"Sevim Bavbek","orcid":"https://orcid.org/0000-0002-7884-0830","observed_orcids":["https://orcid.org/0000-0002-7884-0830"]},"institutions":[{"id":"https://openalex.org/I149218525","display_name":"Ankara University","ror":"https://ror.org/01wntqw50","country_code":"TR","type":"education","lineage":["https://openalex.org/I149218525"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Sevim Bavbek","raw_affiliation_strings":["Division of Allergy and Clinical Immunology, Department of Chest Diseases, School of Medicine Ankara University  Ankara Turkiye"],"raw_orcid":"https://orcid.org/0000-0002-7884-0830","affiliations":[{"raw_affiliation_string":"Division of Allergy and Clinical Immunology, Department of Chest Diseases, School of Medicine Ankara University  Ankara Turkiye","institution_ids":["https://openalex.org/I149218525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063022587","display_name":"Patrizia Bonadonna","orcid":"https://orcid.org/0000-0002-5703-5314","observed_orcids":["https://orcid.org/0000-0002-5703-5314","https://orcid.org/0000-0003-0476-1934","https://orcid.org/0009-0003-9596-1268"]},"institutions":[{"id":"https://openalex.org/I4210152245","display_name":"Ospedale San Bortolo","ror":"https://ror.org/05wd86d64","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210152245"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Patrizia Bonadonna","raw_affiliation_strings":["Allergy Unit San Bortolo Hospital  Vicenza Italy"],"raw_orcid":"https://orcid.org/0000-0002-5703-5314","affiliations":[{"raw_affiliation_string":"Allergy Unit San Bortolo Hospital  Vicenza Italy","institution_ids":["https://openalex.org/I4210152245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025253700","display_name":"Jean Christoph Caubet","orcid":"https://orcid.org/0000-0002-3130-095X","observed_orcids":["https://orcid.org/0000-0002-3130-095X"]},"institutions":[{"id":"https://openalex.org/I4210106256","display_name":"University Hospital of Geneva","ror":"https://ror.org/01m1pv723","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210106256"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Jean\u2010Christoph Caubet","raw_affiliation_strings":["Pediatric Allergy Unit, Department of Woman, Child and Adolescent Geneva University Hospitals  Geneva Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-3130-095X","affiliations":[{"raw_affiliation_string":"Pediatric Allergy Unit, Department of Woman, Child and Adolescent Geneva University Hospitals  Geneva Switzerland","institution_ids":["https://openalex.org/I4210106256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083970705","display_name":"Ana Maria Copaescu","orcid":"https://orcid.org/0000-0002-9183-5032","observed_orcids":["https://orcid.org/0000-0002-9183-5032"]},"institutions":[{"id":"https://openalex.org/I2801766832","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405263283","display_name":"Research Institute of the McGill University Health Centre","ror":"https://ror.org/04pemf943","country_code":"CA","type":"government","lineage":["https://openalex.org/I2801766832","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405263283","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ana\u2010Maria Copaescu","raw_affiliation_strings":["Division of Clinical Immunology and Allergy, Department of Medicine McGill University Health Centre and Research Institute of the McGill University Health Centre  Montreal Quebec Canada"],"raw_orcid":"https://orcid.org/0000-0002-9183-5032","affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Allergy, Department of Medicine McGill University Health Centre and Research Institute of the McGill University Health Centre  Montreal Quebec Canada","institution_ids":["https://openalex.org/I2801766832","https://openalex.org/I4405263283"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106399672","display_name":"Valentina Gueli","orcid":"https://orcid.org/0009-0000-7753-0614","observed_orcids":["https://orcid.org/0009-0000-7753-0614"]},"institutions":[{"id":"https://openalex.org/I119439378","display_name":"University of Verona","ror":"https://ror.org/039bp8j42","country_code":"IT","type":"education","lineage":["https://openalex.org/I119439378"]},{"id":"https://openalex.org/I4210094363","display_name":"Azienda Ospedaliera Universitaria Integrata Verona","ror":"https://ror.org/00sm8k518","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094363"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valentina Gueli","raw_affiliation_strings":["Allergy Unit and Asthma Center University Hospital of Verona, Policlinico G.B. Rossi  Verona Italy"],"raw_orcid":"https://orcid.org/0009-0000-7753-0614","affiliations":[{"raw_affiliation_string":"Allergy Unit and Asthma Center University Hospital of Verona, Policlinico G.B. Rossi  Verona Italy","institution_ids":["https://openalex.org/I119439378","https://openalex.org/I4210094363"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018024332","display_name":"Jos\u00e9 Julio Laguna","orcid":"https://orcid.org/0000-0001-5909-8979","observed_orcids":["https://orcid.org/0000-0001-5909-8979"]},"institutions":[{"id":"https://openalex.org/I4210122155","display_name":"Hospital Central de la Cruz Roja San Jos\u00e9 y Santa Adela","ror":"https://ror.org/01yzgg311","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210122155","https://openalex.org/I4210139293"]},{"id":"https://openalex.org/I4210147442","display_name":"Universidad Alfonso X el Sabio","ror":"https://ror.org/054ewwr15","country_code":"ES","type":"education","lineage":["https://openalex.org/I4210147442"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jose Julio Laguna","raw_affiliation_strings":["Allergy Unit, Allergo\u2010Anaesthesia Unit, Hospital Central de la Cruz Roja, Faculty of Biomedical and Health Sciences Alfonso X El Sabio University, ARADyAL, REI  Madrid Spain"],"raw_orcid":"https://orcid.org/0000-0001-5909-8979","affiliations":[{"raw_affiliation_string":"Allergy Unit, Allergo\u2010Anaesthesia Unit, Hospital Central de la Cruz Roja, Faculty of Biomedical and Health Sciences Alfonso X El Sabio University, ARADyAL, REI  Madrid Spain","institution_ids":["https://openalex.org/I4210122155","https://openalex.org/I4210147442"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079908893","display_name":"Ricardo Madrigal\u2010Burgaleta","orcid":"https://orcid.org/0000-0002-3358-3578","observed_orcids":["https://orcid.org/0000-0002-3358-3578"]},"institutions":[{"id":"https://openalex.org/I1307195382","display_name":"St Bartholomew's Hospital","ror":"https://ror.org/00nh9x179","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]},{"id":"https://openalex.org/I225661044","display_name":"Barts Health NHS Trust","ror":"https://ror.org/00b31g692","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ricardo Madrigal\u2010Burgaleta","raw_affiliation_strings":["Allergy &amp; Severe Asthma Service St Bartholomew's Hospital, Barts Health NHS Trust  London UK"],"raw_orcid":"https://orcid.org/0000-0002-3358-3578","affiliations":[{"raw_affiliation_string":"Allergy &amp; Severe Asthma Service St Bartholomew's Hospital, Barts Health NHS Trust  London UK","institution_ids":["https://openalex.org/I1307195382","https://openalex.org/I225661044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018247576","display_name":"Francesca Mori","orcid":"https://orcid.org/0000-0001-7483-0128","observed_orcids":["https://orcid.org/0000-0001-7483-0128"]},"institutions":[{"id":"https://openalex.org/I4210113625","display_name":"Meyer Children's Hospital","ror":"https://ror.org/01n2xwm51","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210113625"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesca Mori","raw_affiliation_strings":["Allergy Unit Meyer Children's Hospital IRCCS  Florence Italy"],"raw_orcid":"https://orcid.org/0000-0001-7483-0128","affiliations":[{"raw_affiliation_string":"Allergy Unit Meyer Children's Hospital IRCCS  Florence Italy","institution_ids":["https://openalex.org/I4210113625"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044040567","display_name":"Vito Sabato","orcid":"https://orcid.org/0000-0002-1321-314X","observed_orcids":["https://orcid.org/0000-0002-1321-314X"]},"institutions":[{"id":"https://openalex.org/I149213910","display_name":"University of Antwerp","ror":"https://ror.org/008x57b05","country_code":"BE","type":"education","lineage":["https://openalex.org/I149213910"]},{"id":"https://openalex.org/I4210102047","display_name":"Antwerp University Hospital","ror":"https://ror.org/01hwamj44","country_code":"BE","type":"funder","lineage":["https://openalex.org/I4210102047"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Vito Sabato","raw_affiliation_strings":["Immunology Allergology Rheumatology University of Antwerp and Antwerp University Hospital  Antwerp Belgium"],"raw_orcid":"https://orcid.org/0000-0002-1321-314X","affiliations":[{"raw_affiliation_string":"Immunology Allergology Rheumatology University of Antwerp and Antwerp University Hospital  Antwerp Belgium","institution_ids":["https://openalex.org/I149213910","https://openalex.org/I4210102047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100771423","display_name":"Mar\u0131\u0301a Jos\u00e9 Torres","orcid":"https://orcid.org/0000-0001-5228-471X","observed_orcids":["https://orcid.org/0000-0001-5228-471X"]},"institutions":[{"id":"https://openalex.org/I4210108548","display_name":"Hospital Regional Universitario de M\u00e1laga","ror":"https://ror.org/01mqsmm97","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210108548"]},{"id":"https://openalex.org/I4210164724","display_name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga","ror":"https://ror.org/05n3asa33","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210164724"]},{"id":"https://openalex.org/I82767444","display_name":"Universidad de M\u00e1laga","ror":"https://ror.org/036b2ww28","country_code":"ES","type":"education","lineage":["https://openalex.org/I82767444"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Maria J Torres","raw_affiliation_strings":["Allergy Unit Regional University Hospital of Malaga\u2010IBIMA\u2010UMA\u2010ARADyAL  Malaga Spain"],"raw_orcid":"https://orcid.org/0000-0001-5228-471X","affiliations":[{"raw_affiliation_string":"Allergy Unit Regional University Hospital of Malaga\u2010IBIMA\u2010UMA\u2010ARADyAL  Malaga Spain","institution_ids":["https://openalex.org/I4210108548","https://openalex.org/I4210164724","https://openalex.org/I82767444"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023280808","display_name":"Knut Brockow","orcid":"https://orcid.org/0000-0002-2775-3681","observed_orcids":["https://orcid.org/0000-0002-2775-3681"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Knut Brockow","raw_affiliation_strings":["Department of Dermatology and Allergy Biederstein, School of Medicine and Health Technical University of Munich  Munich Germany"],"raw_orcid":"https://orcid.org/0000-0002-2775-3681","affiliations":[{"raw_affiliation_string":"Department of Dermatology and Allergy Biederstein, School of Medicine and Health Technical University of Munich  Munich Germany","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":12,"institutions_distinct_count":29,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5300,"currency":"USD","value_usd":5300},"apc_paid":{"value":5300,"currency":"USD","value_usd":5300},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.62305194,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-hypersensitivity","display_name":"drug hypersensitivity","score":0.9330000281333923},{"id":"https://openalex.org/keywords/skin-testing","display_name":"skin testing","score":0.9269999861717224},{"id":"https://openalex.org/keywords/intradermal-test","display_name":"intradermal test","score":0.7739999890327454},{"id":"https://openalex.org/keywords/patch-testing","display_name":"patch testing","score":0.9950000047683716},{"id":"https://openalex.org/keywords/drug-provocation-test","display_name":"drug provocation test","score":0.7599999904632568},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.6330000162124634},{"id":"https://openalex.org/keywords/maculopapular-exanthema","display_name":"maculopapular exanthema","score":0.9010000228881836},{"id":"https://openalex.org/keywords/clothing","display_name":"clothing","score":0.8050000071525574},{"id":"https://openalex.org/keywords/anca-associated-vasculitis","display_name":"ANCA-associated vasculitis","score":0.7620000243186951},{"id":"https://openalex.org/keywords/contrast-media","display_name":"contrast media","score":0.4449999928474426},{"id":"https://openalex.org/keywords/antibiotics","display_name":"antibiotics","score":0.5879999995231628},{"id":"https://openalex.org/keywords/proton-pump-inhibitors","display_name":"proton pump inhibitors","score":0.8190000057220459},{"id":"https://openalex.org/keywords/biologicals","display_name":"biologicals","score":0.7609999775886536},{"id":"https://openalex.org/keywords/anesthetic-agents","display_name":"anesthetic agents","score":0.6800000071525574},{"id":"https://openalex.org/keywords/negative-control","display_name":"negative control","score":0.46000000834465027},{"id":"https://openalex.org/keywords/standardization","display_name":"standardization","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8998000025749207},{"id":"https://openalex.org/C110586980","wikidata":"https://www.wikidata.org/wiki/Q4168588","display_name":"Provocation test","level":3,"score":0.6919000148773193},{"id":"https://openalex.org/C2779060952","wikidata":"https://www.wikidata.org/wiki/Q2068896","display_name":"Drug allergy","level":3,"score":0.5899999737739563},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5645999908447266},{"id":"https://openalex.org/C2778826181","wikidata":"https://www.wikidata.org/wiki/Q3310538","display_name":"Culprit","level":3,"score":0.522599995136261},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.4625000059604645},{"id":"https://openalex.org/C2775933838","wikidata":"https://www.wikidata.org/wiki/Q168800","display_name":"Anaphylaxis","level":3,"score":0.4002000093460083},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3874000012874603},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3873000144958496},{"id":"https://openalex.org/C2778168870","wikidata":"https://www.wikidata.org/wiki/Q6725808","display_name":"Maculopapular rash","level":3,"score":0.3871000111103058},{"id":"https://openalex.org/C57658597","wikidata":"https://www.wikidata.org/wiki/Q1550789","display_name":"Pharmacovigilance","level":3,"score":0.32199999690055847},{"id":"https://openalex.org/C3017924640","wikidata":"https://www.wikidata.org/wiki/Q7860879","display_name":"Delayed hypersensitivity","level":3,"score":0.3174999952316284},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.30070000886917114},{"id":"https://openalex.org/C2776056826","wikidata":"https://www.wikidata.org/wiki/Q16242752","display_name":"Allergic contact dermatitis","level":3,"score":0.27559998631477356},{"id":"https://openalex.org/C2778091633","wikidata":"https://www.wikidata.org/wiki/Q783903","display_name":"Contact dermatitis","level":3,"score":0.27489998936653137},{"id":"https://openalex.org/C42404028","wikidata":"https://www.wikidata.org/wiki/Q864940","display_name":"Bioequivalence","level":3,"score":0.267300009727478},{"id":"https://openalex.org/C2779121184","wikidata":"https://www.wikidata.org/wiki/Q1166142","display_name":"Erythema","level":2,"score":0.2667999863624573},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2623000144958496},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25519999861717224},{"id":"https://openalex.org/C2987276129","wikidata":"https://www.wikidata.org/wiki/Q12140","display_name":"Drug administration","level":2,"score":0.2551000118255615},{"id":"https://openalex.org/C188087704","wikidata":"https://www.wikidata.org/wiki/Q369577","display_name":"Standardization","level":2,"score":0.2547999918460846},{"id":"https://openalex.org/C3018890749","wikidata":"https://www.wikidata.org/wiki/Q204711","display_name":"Food and drug administration","level":2,"score":0.25450000166893005}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1111/all.70466","doi":"https://doi.org/10.1111/all.70466","is_oa":true,"landing_page_url":"https://doi.org/10.1111/all.70466","pdf_url":null,"source":{"id":"https://openalex.org/S68090385","display_name":"Allergy","issn_l":"0105-4538","issn":["0105-4538","1398-9995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Allergy","raw_type":"journal-article"},{"id":"pmid:42618976","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42618976","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Allergy","raw_type":"Journal Article"},{"id":"pmh:oai:alma.61MUN_INST:11201579670007891","doi":null,"is_oa":true,"landing_page_url":"https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Updated-EAACI-Statement-on-Drug-Hypersensitivity/991005912900707891","pdf_url":null,"source":{"id":"https://openalex.org/S4306400274","display_name":"Murdoch University Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I176790772","host_organization_name":"Murdoch University","host_organization_lineage":["https://openalex.org/I176790772"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":{"id":"doi:10.1111/all.70466","doi":"https://doi.org/10.1111/all.70466","is_oa":true,"landing_page_url":"https://doi.org/10.1111/all.70466","pdf_url":null,"source":{"id":"https://openalex.org/S68090385","display_name":"Allergy","issn_l":"0105-4538","issn":["0105-4538","1398-9995"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Allergy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2047066354","display_name":null,"funder_award_id":"40710","funder_id":"https://openalex.org/F4320327298","funder_display_name":"European Academy of Allergy and Clinical Immunology"}],"funders":[{"id":"https://openalex.org/F4320327298","display_name":"European Academy of Allergy and Clinical Immunology","ror":"https://ror.org/03wa91e11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":98,"referenced_works":["https://openalex.org/W1500498153","https://openalex.org/W1901880560","https://openalex.org/W1977586798","https://openalex.org/W1977782151","https://openalex.org/W1982777554","https://openalex.org/W1983844355","https://openalex.org/W2002716405","https://openalex.org/W2022592338","https://openalex.org/W2094878591","https://openalex.org/W2122435248","https://openalex.org/W2124205535","https://openalex.org/W2214575626","https://openalex.org/W2237606571","https://openalex.org/W2407986678","https://openalex.org/W2533266098","https://openalex.org/W2533769012","https://openalex.org/W2553085252","https://openalex.org/W2559362588","https://openalex.org/W2583001755","https://openalex.org/W2612743517","https://openalex.org/W2730833249","https://openalex.org/W2744859889","https://openalex.org/W2765210349","https://openalex.org/W2778113444","https://openalex.org/W2788252436","https://openalex.org/W2794894495","https://openalex.org/W2884379420","https://openalex.org/W2893526315","https://openalex.org/W2895212220","https://openalex.org/W2914982366","https://openalex.org/W2918450158","https://openalex.org/W2932800610","https://openalex.org/W2940255136","https://openalex.org/W2941778740","https://openalex.org/W2942151834","https://openalex.org/W2960428807","https://openalex.org/W2969200497","https://openalex.org/W2971295168","https://openalex.org/W2989653661","https://openalex.org/W3005804634","https://openalex.org/W3015974187","https://openalex.org/W3021507985","https://openalex.org/W3024205202","https://openalex.org/W3027730910","https://openalex.org/W3042538223","https://openalex.org/W3081719892","https://openalex.org/W3088063984","https://openalex.org/W3089062081","https://openalex.org/W3105124463","https://openalex.org/W3139325228","https://openalex.org/W3171570539","https://openalex.org/W3176452932","https://openalex.org/W3189053302","https://openalex.org/W3202035327","https://openalex.org/W3213096376","https://openalex.org/W3216264025","https://openalex.org/W4200010417","https://openalex.org/W4206595903","https://openalex.org/W4210373031","https://openalex.org/W4212921003","https://openalex.org/W4220652603","https://openalex.org/W4221009030","https://openalex.org/W4281808606","https://openalex.org/W4283774283","https://openalex.org/W4283774898","https://openalex.org/W4284963773","https://openalex.org/W4285028166","https://openalex.org/W4286256600","https://openalex.org/W4295414688","https://openalex.org/W4295564289","https://openalex.org/W4296178925","https://openalex.org/W4296286888","https://openalex.org/W4296709419","https://openalex.org/W4296741107","https://openalex.org/W4297458008","https://openalex.org/W4304701220","https://openalex.org/W4321367841","https://openalex.org/W4321453569","https://openalex.org/W4372203461","https://openalex.org/W4385069226","https://openalex.org/W4385583978","https://openalex.org/W4387191413","https://openalex.org/W4387472464","https://openalex.org/W4387776366","https://openalex.org/W4388223088","https://openalex.org/W4388670111","https://openalex.org/W4389096253","https://openalex.org/W4390410482","https://openalex.org/W4392747385","https://openalex.org/W4393321480","https://openalex.org/W4398182179","https://openalex.org/W4398223257","https://openalex.org/W4400201405","https://openalex.org/W4400380976","https://openalex.org/W4410799823","https://openalex.org/W4413190258","https://openalex.org/W4413720753","https://openalex.org/W7152409412"],"related_works":["https://openalex.org/W2124205535","https://openalex.org/W4412156668","https://openalex.org/W7148480160","https://openalex.org/W4312339887","https://openalex.org/W4285153161","https://openalex.org/W2081732929","https://openalex.org/W2006755305","https://openalex.org/W4312875983","https://openalex.org/W1542823104","https://openalex.org/W2009578062"],"abstract_inverted_index":{"These":[0,205],"updated":[1],"EAACI":[2],"guidelines":[3,119],"aim":[4],"to":[5,47,222,228],"standardize":[6],"skin":[7,176,186,195],"testing":[8,23,40,169,187],"methodologies":[9],"for":[10,61,124,170,201],"both":[11],"immediate":[12,19,63],"and":[13,104,137,199,217,232],"non-immediate":[14],"drug":[15,126,167,190,210,237],"hypersensitivity":[16,238],"reactions.":[17],"For":[18,36,89,193],"reactions,":[20,38],"the":[21,57],"optimal":[22],"window":[24],"is":[25,226],"4-6":[26],"weeks":[27],"post-reaction;":[28],"whereas":[29],"beyond":[30],"6":[31],"months,":[32],"false-negative":[33],"results":[34,231],"increase.":[35],"chemotherapy-related":[37],"earlier":[39],"(within":[41],"2":[42],"weeks)":[43],"remains":[44],"necessary":[45],"due":[46],"treatment":[48],"urgency.":[49],"The":[50,118],"previously":[51],"published":[52],"multicenter":[53],"ENDA":[54],"study":[55],"established":[56],"international":[58],"reference":[59],"method":[60],"positive":[62],"intradermal":[64],"test":[65],"reading:":[66],"injection":[67],"of":[68],"exactly":[69],"0.02":[70],"mL":[71],"with":[72],"a":[73,85],"wheal":[74,81],"at":[75,106],"20":[76],"min":[77],"measuring":[78],"\u2265":[79],"initial":[80],"+3":[82],"mm,":[83],"representing":[84],"major":[86,125],"standardization":[87],"achievement.":[88],"patch":[90],"testing,":[91],"exact":[92],"active":[93],"ingredient":[94],"concentrations":[95,114,123],"must":[96],"be":[97],"systematically":[98],"documented.":[99],"When":[100],"tablets":[101],"are":[102,141,151,159,197],"crushed":[103],"diluted":[105],"30%":[107],"in":[108,112,236],"petrolatum,":[109],"significant":[110],"variability":[111],"final":[113],"has":[115],"been":[116],"observed.":[117],"present":[120],"validated":[121],"nonirritant":[122],"classes":[127],"including":[128],"antibiotics,":[129],"contrast":[130],"media,":[131],"anesthetics,":[132],"proton":[133],"pump":[134],"inhibitors,":[135],"chemotherapies,":[136],"biologicals.":[138],"Specific":[139],"recommendations":[140,150],"based":[142],"on":[143],"negative":[144,157],"controls":[145,158],"demonstrating":[146],"specificity,":[147],"while":[148,213],"conditional":[149],"provided":[152],"when":[153],"few":[154],"or":[155],"no":[156],"available.":[160],"Risk":[161],"stratification":[162],"algorithms":[163],"now":[164],"allow":[165],"direct":[166],"provocation":[168,191],"mild":[171],"maculopapular":[172],"exanthema,":[173],"bypassing":[174],"preliminary":[175],"tests.":[177,192],"However,":[178],"more":[179],"severe":[180],"reactions":[181],"such":[182],"as":[183],"anaphylaxis":[184],"require":[185],"before":[188],"considering":[189],"DRESS/AGEP/SJS/TEN,":[194],"tests":[196],"useful":[198],"safe":[200,209,233],"identifying":[202],"culprit":[203],"drugs.":[204],"harmonized":[206],"methods":[207],"enable":[208],"allergy":[211],"delabeling":[212],"preserving":[214],"diagnostic":[215],"accuracy":[216],"patient":[218],"safety.":[219],"Strict":[220],"adherence":[221],"these":[223],"standardized":[224],"protocols":[225],"essential":[227],"ensure":[229],"reproducible":[230],"clinical":[234],"practice":[235],"evaluation.":[239]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-08-20T00:00:00"}
