{"id":"https://openalex.org/W7203766720","doi":"https://doi.org/10.1007/s00198-026-08150-y","title":"Restoring skeletal remodeling in antiresorptive-treated patients: clinical outcomes of teriparatide in medication-related osteonecrosis of the jaw","display_name":"Restoring skeletal remodeling in antiresorptive-treated patients: clinical outcomes of teriparatide in medication-related osteonecrosis of the jaw","publication_year":2026,"publication_date":"2026-08-19","ids":{"openalex":"https://openalex.org/W7203766720","doi":"https://doi.org/10.1007/s00198-026-08150-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/42616119","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13710568"},"language":"en","primary_location":{"id":"doi:10.1007/s00198-026-08150-y","doi":"https://doi.org/10.1007/s00198-026-08150-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00198-026-08150-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00198-026-08150-y.pdf","source":{"id":"https://openalex.org/S170889201","display_name":"Osteoporosis International","issn_l":"0937-941X","issn":["0937-941X","1433-2965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Osteoporosis International","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00198-026-08150-y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012124486","display_name":"Ana Karina Sarmiento-Li\u00e9vano","orcid":"https://orcid.org/0000-0001-7313-3937","observed_orcids":["https://orcid.org/0000-0001-7313-3937"]},"institutions":[{"id":"https://openalex.org/I162096671","display_name":"Universidad de Los Andes","ror":"https://ror.org/02mhbdp94","country_code":"CO","type":"education","lineage":["https://openalex.org/I162096671"]},{"id":"https://openalex.org/I36243813","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68","country_code":"CO","type":"education","lineage":["https://openalex.org/I36243813"]},{"id":"https://openalex.org/I4210132175","display_name":"Fundaci\u00f3n Santa Fe de Bogot\u00e1","ror":"https://ror.org/03ezapm74","country_code":"CO","type":"nonprofit","lineage":["https://openalex.org/I4210132175"]}],"countries":["CO"],"is_corresponding":true,"raw_author_name":"Ana Karina Sarmiento Li\u00e9vano","raw_affiliation_strings":["Faculty of Medicine, Universidad de los Andes, Bogot\u00e1, Colombia. ana.sarmiento@fsfb.org.co","Fundaci\u00f3n Santa Fe de Bogot\u00e1, Bogot\u00e1, Colombia. ana.sarmiento@fsfb.org.co","Oral and Maxillofacial Surgery Postgraduate Program, Universidad Nacional de Colombia, Bogot\u00e1, Colombia. ana.sarmiento@fsfb.org.co"],"raw_orcid":"https://orcid.org/0000-0001-7313-3937","affiliations":[{"raw_affiliation_string":"Faculty of Medicine, Universidad de los Andes, Bogot\u00e1, Colombia. ana.sarmiento@fsfb.org.co","institution_ids":["https://openalex.org/I162096671"]},{"raw_affiliation_string":"Fundaci\u00f3n Santa Fe de Bogot\u00e1, Bogot\u00e1, Colombia. ana.sarmiento@fsfb.org.co","institution_ids":["https://openalex.org/I4210132175"]},{"raw_affiliation_string":"Oral and Maxillofacial Surgery Postgraduate Program, Universidad Nacional de Colombia, Bogot\u00e1, Colombia. ana.sarmiento@fsfb.org.co","institution_ids":["https://openalex.org/I36243813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147478958","display_name":"Hannah Vanessa Ceballos Sarmiento","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162096671","display_name":"Universidad de Los Andes","ror":"https://ror.org/02mhbdp94","country_code":"CO","type":"education","lineage":["https://openalex.org/I162096671"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Hannah Vanessa Ceballos Sarmiento","raw_affiliation_strings":["Biomedical Engineering Department, Universidad de los Andes, Bogot\u00e1, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Department, Universidad de los Andes, Bogot\u00e1, Colombia","institution_ids":["https://openalex.org/I162096671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147489440","display_name":"Nicol\u00e1s Jim\u00e9nez Vega","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36243813","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68","country_code":"CO","type":"education","lineage":["https://openalex.org/I36243813"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Nicol\u00e1s Jim\u00e9nez Vega","raw_affiliation_strings":["Oral and Maxillofacial Surgery Postgraduate Program, Universidad Nacional de Colombia, Bogot\u00e1, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Oral and Maxillofacial Surgery Postgraduate Program, Universidad Nacional de Colombia, Bogot\u00e1, Colombia","institution_ids":["https://openalex.org/I36243813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147610012","display_name":"Yeisson Alejandro Arias Avila","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36243813","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68","country_code":"CO","type":"education","lineage":["https://openalex.org/I36243813"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Yeisson Alejandro Arias Avila","raw_affiliation_strings":["School of Dentistry, Universidad Nacional de Colombia, Bogot\u00e1, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Dentistry, Universidad Nacional de Colombia, Bogot\u00e1, Colombia","institution_ids":["https://openalex.org/I36243813"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5147625114","display_name":"Maria Paula Monroy Becerra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36243813","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68","country_code":"CO","type":"education","lineage":["https://openalex.org/I36243813"]}],"countries":["CO"],"is_corresponding":false,"raw_author_name":"Maria Paula Monroy Becerra","raw_affiliation_strings":["School of Dentistry, Universidad Nacional de Colombia, Bogot\u00e1, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Dentistry, Universidad Nacional de Colombia, Bogot\u00e1, Colombia","institution_ids":["https://openalex.org/I36243813"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5012124486"],"corresponding_institution_ids":["https://openalex.org/I162096671","https://openalex.org/I36243813","https://openalex.org/I4210132175"],"apc_list":{"value":5090,"currency":"USD","value_usd":5090},"apc_paid":{"value":5090,"currency":"USD","value_usd":5090},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.4096651,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"37","issue":"9","first_page":"2291","last_page":"2312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12198","display_name":"Oral health in cancer treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/teriparatide","display_name":"teriparatide","score":0.8870000243186951},{"id":"https://openalex.org/keywords/medication-related-osteonecrosis-of-the-jaw","display_name":"medication-related osteonecrosis of the jaw","score":0.996999979019165},{"id":"https://openalex.org/keywords/antiresorptive-therapy","display_name":"antiresorptive therapy","score":0.8759999871253967},{"id":"https://openalex.org/keywords/bisphosphonates","display_name":"bisphosphonates","score":0.8949999809265137},{"id":"https://openalex.org/keywords/denosumab","display_name":"denosumab","score":0.9950000047683716},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.7490000128746033},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.8830000162124634},{"id":"https://openalex.org/keywords/anabolic-therapy","display_name":"anabolic therapy","score":0.9160000085830688},{"id":"https://openalex.org/keywords/mandibular-lesion","display_name":"mandibular lesion","score":0.6779999732971191},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C2777308945","wikidata":"https://www.wikidata.org/wiki/Q411781","display_name":"Teriparatide","level":4,"score":0.9868000149726868},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9491999745368958},{"id":"https://openalex.org/C2777556957","wikidata":"https://www.wikidata.org/wiki/Q2377991","display_name":"Osteonecrosis of the jaw","level":4,"score":0.84170001745224},{"id":"https://openalex.org/C2777251235","wikidata":"https://www.wikidata.org/wiki/Q412205","display_name":"Bisphosphonate","level":3,"score":0.6895999908447266},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.6722000241279602},{"id":"https://openalex.org/C2776286101","wikidata":"https://www.wikidata.org/wiki/Q408283","display_name":"Denosumab","level":3,"score":0.616599977016449},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.6133999824523926},{"id":"https://openalex.org/C2779921893","wikidata":"https://www.wikidata.org/wiki/Q866622","display_name":"Bisphosphonate-associated osteonecrosis of the jaw","level":5,"score":0.5295000076293945},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.48910000920295715},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.4381999969482422},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42489999532699585},{"id":"https://openalex.org/C2911223091","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone Density Conservation Agents","level":4,"score":0.39649999141693115},{"id":"https://openalex.org/C2777288759","wikidata":"https://www.wikidata.org/wiki/Q4164182","display_name":"Dosing","level":2,"score":0.3797999918460846},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.37220001220703125},{"id":"https://openalex.org/C3454156","wikidata":"https://www.wikidata.org/wiki/Q1144241","display_name":"Side effect (computer science)","level":2,"score":0.3718999922275543},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3637999892234802},{"id":"https://openalex.org/C68312169","wikidata":"https://www.wikidata.org/wiki/Q216685","display_name":"Orthopedic surgery","level":2,"score":0.3562999963760376},{"id":"https://openalex.org/C2776326535","wikidata":"https://www.wikidata.org/wiki/Q218507","display_name":"Zoledronic acid","level":2,"score":0.35510000586509705},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.35010001063346863},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.32359999418258667},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3027999997138977},{"id":"https://openalex.org/C2776169692","wikidata":"https://www.wikidata.org/wiki/Q4941552","display_name":"Bone disease","level":3,"score":0.2870999872684479},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.27709999680519104},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.272599995136261},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.27149999141693115},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.26930001378059387},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.25949999690055847}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016723","descriptor_name":"Bone Remodeling","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019379","descriptor_name":"Teriparatide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D050071","descriptor_name":"Bone Density Conservation Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D050071","descriptor_name":"Bone Density Conservation Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D050071","descriptor_name":"Bone Density Conservation Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D059266","descriptor_name":"Bisphosphonate-Associated Osteonecrosis of the Jaw","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D059266","descriptor_name":"Bisphosphonate-Associated Osteonecrosis of the Jaw","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D059266","descriptor_name":"Bisphosphonate-Associated Osteonecrosis of the Jaw","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00198-026-08150-y","doi":"https://doi.org/10.1007/s00198-026-08150-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00198-026-08150-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00198-026-08150-y.pdf","source":{"id":"https://openalex.org/S170889201","display_name":"Osteoporosis International","issn_l":"0937-941X","issn":["0937-941X","1433-2965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Osteoporosis International","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13710568","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13710568/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13710568/pdf/198_2026_Article_8150.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Osteoporos Int","raw_type":"Text"},{"id":"pmid:42616119","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42616119","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s00198-026-08150-y","doi":"https://doi.org/10.1007/s00198-026-08150-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00198-026-08150-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00198-026-08150-y.pdf","source":{"id":"https://openalex.org/S170889201","display_name":"Osteoporosis International","issn_l":"0937-941X","issn":["0937-941X","1433-2965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Osteoporosis International","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321458","display_name":"Universidad Nacional de Colombia","ror":"https://ror.org/059yx9a68"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203766720.pdf","grobid_xml":"https://content.openalex.org/works/W7203766720.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W1197792539","https://openalex.org/W1970791435","https://openalex.org/W1988260211","https://openalex.org/W1993848781","https://openalex.org/W2016147578","https://openalex.org/W2037259033","https://openalex.org/W2043133670","https://openalex.org/W2044210719","https://openalex.org/W2051162296","https://openalex.org/W2055293789","https://openalex.org/W2068621216","https://openalex.org/W2089035363","https://openalex.org/W2093978682","https://openalex.org/W2100123170","https://openalex.org/W2136070713","https://openalex.org/W2164955521","https://openalex.org/W2290823109","https://openalex.org/W2335178464","https://openalex.org/W2402140459","https://openalex.org/W2597426812","https://openalex.org/W2748398257","https://openalex.org/W2807268208","https://openalex.org/W2892850068","https://openalex.org/W2896174631","https://openalex.org/W2945936907","https://openalex.org/W2961332767","https://openalex.org/W2969838873","https://openalex.org/W2980469029","https://openalex.org/W2990132593","https://openalex.org/W3008392623","https://openalex.org/W3012208209","https://openalex.org/W3038385682","https://openalex.org/W3039317401","https://openalex.org/W3040350801","https://openalex.org/W3041067399","https://openalex.org/W3083952170","https://openalex.org/W3118615836","https://openalex.org/W3125359716","https://openalex.org/W3144907926","https://openalex.org/W3200474062","https://openalex.org/W3208549776","https://openalex.org/W4200389828","https://openalex.org/W4213264012","https://openalex.org/W4286764453","https://openalex.org/W4295907275","https://openalex.org/W4304758424","https://openalex.org/W4309368148","https://openalex.org/W4309890089","https://openalex.org/W4313455245","https://openalex.org/W4388416241","https://openalex.org/W4396590489","https://openalex.org/W4403929812","https://openalex.org/W4409328239","https://openalex.org/W4409372269"],"related_works":["https://openalex.org/W3038385682","https://openalex.org/W3040580470","https://openalex.org/W3008392623","https://openalex.org/W3187007634","https://openalex.org/W3208549776","https://openalex.org/W7163640234","https://openalex.org/W7037151112","https://openalex.org/W3049648640","https://openalex.org/W7168304594","https://openalex.org/W4403929812"],"abstract_inverted_index":{"Medication-related":[0],"osteonecrosis":[1],"of":[2,18,56,89,97,123],"the":[3,98,193,239],"jaw":[4],"(MRONJ)":[5],"is":[6],"a":[7,25,44,62,68,74,253],"challenging":[8],"complication":[9],"associated":[10],"with":[11,82],"antiresorptive":[12,111,115,117,221],"and":[13,78,119,132,167,198,244],"antiangiogenic":[14],"therapies.":[15,249],"Prolonged":[16],"suppression":[17],"bone":[19,38],"remodeling":[20],"has":[21,40],"been":[22,41],"implicated":[23],"as":[24,43,266],"key":[26],"mechanism":[27],"in":[28,59,80,91,126,157,161,165,169,180,236],"its":[29],"pathophysiology.":[30],"Teriparatide,":[31],"an":[32],"osteoanabolic":[33],"agent":[34],"that":[35],"restores":[36],"coupled":[37],"remodeling,":[39],"proposed":[42],"potential":[45],"therapeutic":[46,87],"strategy.":[47],"This":[48],"review":[49,71],"aimed":[50],"to":[51],"synthesize":[52],"reported":[53,79,156,179,205],"clinical":[54,120,231],"outcomes":[55,147],"teriparatide":[57,90,113,200,234,265],"use":[58,88,235],"MRONJ":[60,93,107],"within":[61],"systemic":[63],"remodeling-based":[64,256],"framework.":[65],"We":[66],"conducted":[67],"structured":[69],"descriptive":[70],"based":[72],"on":[73,104],"systematic":[75],"literature":[76],"search":[77],"accordance":[81],"PRISMA":[83],"2020.":[84],"Studies":[85],"reporting":[86],"established":[92],"were":[94,102,144,148,215],"included":[95],"regardless":[96],"triggering":[99],"medication.":[100],"Data":[101],"extracted":[103],"patient":[105,129],"characteristics,":[106],"stage,":[108],"lesion":[109],"site,":[110,197],"exposure,":[112],"regimen,":[114],"interruption,":[116],"type,":[118],"outcomes.":[121],"Because":[122],"substantial":[124],"heterogeneity":[125],"study":[127],"design,":[128],"populations,":[130],"co-interventions,":[131],"outcome":[133],"reporting,":[134],"evidence":[135,240],"was":[136,155,178,192,202],"synthesized":[137],"qualitatively.":[138],"Thirty-four":[139],"publications":[140],"including":[141],"207":[142],"patients":[143],"included.":[145],"Clinical":[146],"available":[149],"for":[150],"201":[151],"patients:":[152],"complete":[153],"coverage/healing":[154],"163,":[158],"partial":[159],"improvement":[160,232],"24,":[162],"no":[163],"change":[164],"12,":[166],"worsening":[168],"2.":[170],"Teriparatide":[171],"discontinuation":[172],"or":[173,263],"dropout":[174],"after":[175,233],"treatment":[176],"initiation":[177],"13":[181],"patients.":[182],"Stage":[183],"2":[184],"disease":[185],"predominated":[186],"among":[187],"stageable":[188],"cases,":[189],"mandibular":[190],"involvement":[191],"most":[194],"frequent":[195,230],"anatomical":[196],"daily":[199],"dosing":[201],"more":[203],"commonly":[204,245],"than":[206],"weekly":[207],"regimens.":[208],"Bisphosphonate":[209],"exposure":[210],"predominated,":[211],"whereas":[212],"denosumab-associated":[213],"cases":[214],"fewer;":[216],"therefore,":[217],"differential":[218],"effectiveness":[219],"by":[220,247],"class":[222],"could":[223],"not":[224,260],"be":[225],"determined.":[226],"Published":[227],"reports":[228],"describe":[229],"MRONJ.":[237],"However,":[238],"remains":[241],"descriptive,":[242],"heterogeneous,":[243],"confounded":[246],"concomitant":[248],"These":[250],"findings":[251],"support":[252],"biologically":[254],"plausible":[255],"interpretation":[257],"but":[258],"do":[259],"establish":[261],"efficacy":[262],"define":[264],"standard":[267],"therapy.":[268]},"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2026-08-20T00:00:00"}