{"id":"https://openalex.org/W7203752041","doi":"https://doi.org/10.20961/carakatani.v41i3.119421","title":"Advanced Hybrid RSM-ANN-GA Modeling for Efficient Ultrasound-Assisted Hot-Water Extraction of Polyphenol-Rich Bioactives from Pilangkasa Fruit","display_name":"Advanced Hybrid RSM-ANN-GA Modeling for Efficient Ultrasound-Assisted Hot-Water Extraction of Polyphenol-Rich Bioactives from Pilangkasa Fruit","publication_year":2026,"publication_date":"2026-08-06","ids":{"openalex":"https://openalex.org/W7203752041","doi":"https://doi.org/10.20961/carakatani.v41i3.119421"},"language":"en","primary_location":{"id":"doi:10.20961/carakatani.v41i3.119421","doi":"https://doi.org/10.20961/carakatani.v41i3.119421","is_oa":true,"landing_page_url":"https://doi.org/10.20961/carakatani.v41i3.119421","pdf_url":"https://jurnal.uns.ac.id/carakatani/article/download/119421/pdf","source":{"id":"https://openalex.org/S4210235406","display_name":"Caraka Tani Journal of Sustainable Agriculture","issn_l":"2613-9456","issn":["2613-9456","2599-2570"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d"],"host_organization":"https://openalex.org/P4310315210","host_organization_name":"Sebelas Maret University","host_organization_lineage":["https://openalex.org/P4310315210"],"host_organization_lineage_names":["Sebelas Maret University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caraka Tani: Journal of Sustainable Agriculture","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jurnal.uns.ac.id/carakatani/article/download/119421/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5116464754","display_name":"Chaiyut Mansamut","orcid":"https://orcid.org/0009-0003-2497-9751","observed_orcids":["https://orcid.org/0009-0003-2497-9751"]},"institutions":[{"id":"https://openalex.org/I4210125673","display_name":"Dhonburi Rajabhat University","ror":"https://ror.org/03mzvzx07","country_code":"TH","type":"education","lineage":["https://openalex.org/I4210125673"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Chaiyut Mansamut","raw_affiliation_strings":["Faculty of Science and Technology, Dhonburi Rajabhat University, Thon Buri district, Bangkok"],"raw_orcid":"https://orcid.org/0009-0003-2497-9751","affiliations":[{"raw_affiliation_string":"Faculty of Science and Technology, Dhonburi Rajabhat University, Thon Buri district, Bangkok","institution_ids":["https://openalex.org/I4210125673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011706102","display_name":"The Vinh Bui","orcid":"https://orcid.org/0000-0002-6958-3852","observed_orcids":["https://orcid.org/0000-0002-6958-3852"]},"institutions":[{"id":"https://openalex.org/I4405259954","display_name":"Mekong University","ror":"https://ror.org/02zjr9h86","country_code":"VN","type":"education","lineage":["https://openalex.org/I4405259954"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Bui The Vinh","raw_affiliation_strings":["Faculty of Graduate Studies, Mekong University (MKU), National Highway 1A, Phu Quoi Ward, Vinh Long Province"],"raw_orcid":"https://orcid.org/0000-0002-6958-3852","affiliations":[{"raw_affiliation_string":"Faculty of Graduate Studies, Mekong University (MKU), National Highway 1A, Phu Quoi Ward, Vinh Long Province","institution_ids":["https://openalex.org/I4405259954"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087392541","display_name":"Le Thi Kim Loan","orcid":"https://orcid.org/0000-0001-7472-8334","observed_orcids":["https://orcid.org/0000-0001-7472-8334"]},"institutions":[{"id":"https://openalex.org/I4405277112","display_name":"Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Ti\u1ec1n Giang","ror":"https://ror.org/01gff7046","country_code":"VN","type":"education","lineage":["https://openalex.org/I4405277112"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Le Thi Kim Loan","raw_affiliation_strings":["Faculty of Agriculture and Food Technology, Tien Giang University, Dong Thap Province"],"raw_orcid":"https://orcid.org/0000-0001-7472-8334","affiliations":[{"raw_affiliation_string":"Faculty of Agriculture and Food Technology, Tien Giang University, Dong Thap Province","institution_ids":["https://openalex.org/I4405277112"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1000000,"currency":"IDR","value_usd":65},"apc_paid":{"value":1000000,"currency":"IDR","value_usd":65},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"3","first_page":"374","last_page":"374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12181","display_name":"Agricultural and Biological Research","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11842","display_name":"Ultrasound and Cavitation Phenomena","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3102","display_name":"Acoustics and Ultrasonics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrasound-assisted-extraction","display_name":"ultrasound-assisted extraction","score":0.828000009059906},{"id":"https://openalex.org/keywords/hot-water-extraction","display_name":"hot water extraction","score":0.8669999837875366},{"id":"https://openalex.org/keywords/ardisia-elliptica","display_name":"Ardisia elliptica","score":0.9380000233650208},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.9909999966621399},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.8539999723434448},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8629999756813049},{"id":"https://openalex.org/keywords/extraction-optimization","display_name":"extraction optimization","score":0.7390000224113464},{"id":"https://openalex.org/keywords/cavitation","display_name":"cavitation","score":0.4819999933242798},{"id":"https://openalex.org/keywords/sonochemical-degradation","display_name":"sonochemical degradation","score":0.7540000081062317},{"id":"https://openalex.org/keywords/hybrid-ann-ga-model","display_name":"hybrid ANN-GA model","score":0.6320000290870667},{"id":"https://openalex.org/keywords/total-phenolic-content","display_name":"total phenolic content","score":0.7279999852180481},{"id":"https://openalex.org/keywords/total-flavonoid-content","display_name":"total flavonoid content","score":0.8920000195503235}],"concepts":[{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.8012999892234802},{"id":"https://openalex.org/C150077022","wikidata":"https://www.wikidata.org/wiki/Q3136137","display_name":"Response surface methodology","level":2,"score":0.714900016784668},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.7020000219345093},{"id":"https://openalex.org/C2781401929","wikidata":"https://www.wikidata.org/wiki/Q5205953","display_name":"DPPH","level":3,"score":0.5583999752998352},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.553600013256073},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5440000295639038},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.47119998931884766},{"id":"https://openalex.org/C2779679103","wikidata":"https://www.wikidata.org/wiki/Q5251805","display_name":"Degradation (telecommunications)","level":2,"score":0.46219998598098755},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.40950000286102295},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.35679998993873596},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.35350000858306885},{"id":"https://openalex.org/C45804977","wikidata":"https://www.wikidata.org/wiki/Q7239673","display_name":"Predictive modelling","level":2,"score":0.3228999972343445},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.3156000077724457},{"id":"https://openalex.org/C21880701","wikidata":"https://www.wikidata.org/wiki/Q2144042","display_name":"Process engineering","level":1,"score":0.28450000286102295},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.27410000562667847},{"id":"https://openalex.org/C2993539680","wikidata":"https://www.wikidata.org/wiki/Q902552","display_name":"Antioxidant capacity","level":3,"score":0.2689000070095062},{"id":"https://openalex.org/C2778395939","wikidata":"https://www.wikidata.org/wiki/Q2160967","display_name":"Water extraction","level":3,"score":0.25130000710487366}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.20961/carakatani.v41i3.119421","doi":"https://doi.org/10.20961/carakatani.v41i3.119421","is_oa":true,"landing_page_url":"https://doi.org/10.20961/carakatani.v41i3.119421","pdf_url":"https://jurnal.uns.ac.id/carakatani/article/download/119421/pdf","source":{"id":"https://openalex.org/S4210235406","display_name":"Caraka Tani Journal of Sustainable Agriculture","issn_l":"2613-9456","issn":["2613-9456","2599-2570"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d"],"host_organization":"https://openalex.org/P4310315210","host_organization_name":"Sebelas Maret University","host_organization_lineage":["https://openalex.org/P4310315210"],"host_organization_lineage_names":["Sebelas Maret University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caraka Tani: Journal of Sustainable Agriculture","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:84b38679b81b4c979fdf9062a1aa3e0f","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/84b38679b81b4c979fdf9062a1aa3e0f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Caraka Tani: Journal of Sustainable Agriculture, Vol 41, Iss 3, Pp 374-391 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.20961/carakatani.v41i3.119421","doi":"https://doi.org/10.20961/carakatani.v41i3.119421","is_oa":true,"landing_page_url":"https://doi.org/10.20961/carakatani.v41i3.119421","pdf_url":"https://jurnal.uns.ac.id/carakatani/article/download/119421/pdf","source":{"id":"https://openalex.org/S4210235406","display_name":"Caraka Tani Journal of Sustainable Agriculture","issn_l":"2613-9456","issn":["2613-9456","2599-2570"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d"],"host_organization":"https://openalex.org/P4310315210","host_organization_name":"Sebelas Maret University","host_organization_lineage":["https://openalex.org/P4310315210"],"host_organization_lineage_names":["Sebelas Maret University"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Caraka Tani: Journal of Sustainable Agriculture","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5925999879837036,"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203752041.pdf","grobid_xml":"https://content.openalex.org/works/W7203752041.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W2029079908","https://openalex.org/W2050261211","https://openalex.org/W2072435855","https://openalex.org/W2092111183","https://openalex.org/W2098261708","https://openalex.org/W2471898040","https://openalex.org/W2566837585","https://openalex.org/W2582666522","https://openalex.org/W2917910626","https://openalex.org/W3149181705","https://openalex.org/W3169887542","https://openalex.org/W3183567923","https://openalex.org/W3185670020","https://openalex.org/W3199981457","https://openalex.org/W4200215382","https://openalex.org/W4223633199","https://openalex.org/W4296890816","https://openalex.org/W4320040151","https://openalex.org/W4322770947","https://openalex.org/W4376891778","https://openalex.org/W4388723594","https://openalex.org/W4393235148","https://openalex.org/W4396812284","https://openalex.org/W4401271993","https://openalex.org/W4401419385","https://openalex.org/W4408201043","https://openalex.org/W4409734183","https://openalex.org/W4412569562","https://openalex.org/W4412989118","https://openalex.org/W4414136331","https://openalex.org/W4414872006","https://openalex.org/W4416829634","https://openalex.org/W4417181605","https://openalex.org/W4417525031","https://openalex.org/W7118118502","https://openalex.org/W7133898401","https://openalex.org/W7147375119","https://openalex.org/W7147768267","https://openalex.org/W7153478956","https://openalex.org/W7165009983"],"related_works":["https://openalex.org/W4390637534","https://openalex.org/W2983944565","https://openalex.org/W2982717364","https://openalex.org/W3082647363","https://openalex.org/W4318776398","https://openalex.org/W4406337628","https://openalex.org/W4250413554","https://openalex.org/W7170678851","https://openalex.org/W7165956461","https://openalex.org/W7127378005"],"abstract_inverted_index":{"Pilangkasa":[0],"(Ardisia":[1],"elliptica":[2],"Thunb.)":[3],"is":[4],"a":[5,20],"source":[6],"of":[7,46,72,114,162,184,190,196,200,227],"natural":[8],"antioxidants":[9],"with":[10,112,213],"potential":[11,226],"applications.":[12],"Ultrasound-assisted":[13],"extraction":[14,25,28,73,125,233],"(UAE)":[15],"has":[16],"been":[17],"proposed":[18],"as":[19],"sustainable":[21],"alternative":[22],"to":[23,42,68,76,81,88,119,129,171],"conventional":[24],"methods,":[26],"but":[27],"efficiency":[29],"highly":[30,110],"depends":[31],"on":[32,90],"processing":[33],"conditions.":[34,221],"Therefore,":[35],"the":[36,44,70,91,123,131,142,159,168,225,239],"present":[37],"study":[38,69],"was":[39,66,127,141,152],"carried":[40],"out":[41],"optimize":[43],"UAE":[45],"phytochemicals":[47],"from":[48,117],"polyphenol-rich":[49],"fruit":[50],"using":[51],"Response":[52],"Surface":[53],"Methodology":[54],"(RSM)":[55],"and":[56,84,100,104,147,158,177,198,216,235],"Artificial":[57],"Neural":[58],"Network-Genetic":[59],"Algorithm":[60],"(ANN-GA)":[61],"modeling.":[62],"A":[63],"Box-Behnken":[64],"design":[65],"used":[67],"effects":[71],"temperature":[74],"(50":[75,87],"70":[77],"\u00b0C),":[78],"time":[79,126],"(10":[80],"30":[82],"minutes),":[83],"ultrasonic":[85,179],"power":[86],"70%)":[89],"total":[92,96],"phenolic":[93],"content":[94,98],"(TPC),":[95],"flavonoid":[97],"(TFC),":[99],"antioxidant":[101,150],"activities":[102],"(DPPH":[103],"FRAP).":[105],"The":[106,164,205],"RSM":[107],"models":[108],"were":[109],"predictive":[111],"coefficients":[113],"determination":[115],"ranging":[116],"85.52":[118],"98.71%.":[120],"Among":[121],"all":[122],"responses,":[124],"found":[128],"be":[130,172],"most":[132],"influential":[133],"factor.":[134],"Results":[135],"indicated":[136],"that":[137],"cavitation-enhanced":[138],"mass":[139],"transfer":[140],"main":[143],"factor":[144],"influencing":[145],"TPC":[146,183],"TFC,":[148],"whereas":[149],"activity":[151],"greatly":[153],"influenced":[154],"by":[155],"structural":[156],"stability":[157],"sonochemical":[160],"degradation":[161],"polyphenols.":[163],"hybrid":[165,228],"RSM-ANN-GA":[166],"predicted":[167,219],"optimal":[169,220],"conditions":[170],"60.2":[173],"\u00b0C,":[174],"22.45":[175],"minutes,":[176],"60.34%":[178],"power,":[180],"resulting":[181],"in":[182],"92.24":[185],"mg":[186,192,202],"GAE":[187],"g-1,":[188,194],"TFC":[189],"175.35":[191],"QE":[193],"DPPH":[195],"81.27%,":[197],"FRAP":[199],"1.61":[201],"TE":[203],"g-1.":[204],"ANN-GA":[206],"model":[207],"showed":[208],"better":[209],"prediction":[210],"than":[211],"RSM,":[212],"high":[214],"correlation":[215],"slightly":[217],"improved":[218],"These":[222],"results":[223],"illustrate":[224],"modeling":[229],"approaches":[230],"for":[231],"optimizing":[232],"processes":[234],"provide":[236],"insights":[237],"into":[238],"physicochemical":[240],"mechanisms":[241],"underlying":[242],"polyphenol":[243],"recovery.":[244]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-08-20T00:00:00"}