{"id":"https://openalex.org/W7203669100","doi":"https://doi.org/10.3389/fped.2026.1935719","title":"Serum phoenixin-14 shows no association with metabolic syndrome in children with obesity: a cross-sectional study","display_name":"Serum phoenixin-14 shows no association with metabolic syndrome in children with obesity: a cross-sectional study","publication_year":2026,"publication_date":"2026-08-18","ids":{"openalex":"https://openalex.org/W7203669100","doi":"https://doi.org/10.3389/fped.2026.1935719","pmid":"https://pubmed.ncbi.nlm.nih.gov/42682647","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13529971"},"language":"en","primary_location":{"id":"doi:10.3389/fped.2026.1935719","doi":"https://doi.org/10.3389/fped.2026.1935719","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1935719","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1935719/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1935719/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038789684","display_name":"Zafer Ba\u011fc\u0131","orcid":"https://orcid.org/0000-0003-4776-7236","observed_orcids":["https://orcid.org/0000-0003-4776-7236"]},"institutions":[{"id":"https://openalex.org/I4210128276","display_name":"Sa\u011fl\u0131k Bilimleri \u00dcniversitesi","ror":"https://ror.org/03k7bde87","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210128276"]},{"id":"https://openalex.org/I4405257176","display_name":"Konya City Hospital","ror":"https://ror.org/04ze00805","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4405257176"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Zafer Ba\u011fc\u0131","raw_affiliation_strings":["Department of Pediatrics, Konya City Hospital, University of Health Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Konya City Hospital, University of Health Sciences","institution_ids":["https://openalex.org/I4210128276","https://openalex.org/I4405257176"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007092528","display_name":"Rukiye Uyan\u0131k","orcid":"https://orcid.org/0000-0001-5461-4233","observed_orcids":["https://orcid.org/0000-0001-5461-4233"]},"institutions":[{"id":"https://openalex.org/I4405257176","display_name":"Konya City Hospital","ror":"https://ror.org/04ze00805","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4405257176"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Rukiye Uyan\u0131k","raw_affiliation_strings":["Department of Pediatric Endocrinology, Konya City Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Endocrinology, Konya City Hospital","institution_ids":["https://openalex.org/I4405257176"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031399925","display_name":"\u00dcmm\u00fcg\u00fcls\u00fcm Can","orcid":"https://orcid.org/0000-0002-8967-2924","observed_orcids":["https://orcid.org/0000-0002-8967-2924"]},"institutions":[{"id":"https://openalex.org/I4405257176","display_name":"Konya City Hospital","ror":"https://ror.org/04ze00805","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4405257176"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u00dcmm\u00fcg\u00fcls\u00fcm Can","raw_affiliation_strings":["Department of Biochemistry, Konya City Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Konya City Hospital","institution_ids":["https://openalex.org/I4405257176"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147440092","display_name":"Deniz Y\u0131lmaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257176","display_name":"Konya City Hospital","ror":"https://ror.org/04ze00805","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4405257176"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Deniz Y\u0131lmaz","raw_affiliation_strings":["Department of Biochemistry, Konya City Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Konya City Hospital","institution_ids":["https://openalex.org/I4405257176"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000467096","display_name":"Sadinaz Akdu","orcid":"https://orcid.org/0000-0002-0585-1029","observed_orcids":["https://orcid.org/0000-0002-0585-1029"]},"institutions":[{"id":"https://openalex.org/I4405253527","display_name":"Fethi\u0307ye Devlet Hastanesi\u0307","ror":"https://ror.org/00sda7m35","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4405253527"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Sadinaz Akdu","raw_affiliation_strings":["Department of Biochemistry, Fethiye State Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Fethiye State Hospital","institution_ids":["https://openalex.org/I4405253527"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5038789684"],"corresponding_institution_ids":["https://openalex.org/I4210128276","https://openalex.org/I4405257176"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":"1935719","last_page":"1935719"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6234999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6234999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.27489998936653137,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.03550000116229057,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuropeptides","display_name":"neuropeptides","score":0.7260000109672546},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.781000018119812},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8889999985694885},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.8460000157356262},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.7440000176429749},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.8659999966621399},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.5809999704360962},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.3310000002384186},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.4320000112056732},{"id":"https://openalex.org/keywords/reproductive-hormones","display_name":"reproductive hormones","score":0.4519999921321869},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.42399999499320984},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.5040000081062317},{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.5090000033378601},{"id":"https://openalex.org/keywords/tanner-stages","display_name":"Tanner stages","score":0.5770000219345093},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.38100001215934753},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8909000158309937},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.8098999857902527},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6743000149726868},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6085000038146973},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4661000072956085},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.46219998598098755},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4611000120639801},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.44350001215934753},{"id":"https://openalex.org/C3018667095","wikidata":"https://www.wikidata.org/wiki/Q3455903","display_name":"Glucose homeostasis","level":4,"score":0.43849998712539673},{"id":"https://openalex.org/C2780546910","wikidata":"https://www.wikidata.org/wiki/Q185690","display_name":"Adrenocorticotropic hormone","level":3,"score":0.3889000117778778},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.37299999594688416},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.3677999973297119},{"id":"https://openalex.org/C2780420688","wikidata":"https://www.wikidata.org/wiki/Q759183","display_name":"Immunoassay","level":3,"score":0.36149999499320984},{"id":"https://openalex.org/C2778901321","wikidata":"https://www.wikidata.org/wiki/Q7268928","display_name":"Quantitative insulin sensitivity check index","level":5,"score":0.3521000146865845},{"id":"https://openalex.org/C30092816","wikidata":"https://www.wikidata.org/wiki/Q419613","display_name":"Sex hormone-binding globulin","level":4,"score":0.3334999978542328},{"id":"https://openalex.org/C2777693730","wikidata":"https://www.wikidata.org/wiki/Q1140549","display_name":"Abdominal obesity","level":4,"score":0.3151000142097473},{"id":"https://openalex.org/C2779422640","wikidata":"https://www.wikidata.org/wiki/Q3241451","display_name":"Childhood obesity","level":4,"score":0.30799999833106995},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.30630001425743103},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.30000001192092896},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.29750001430511475},{"id":"https://openalex.org/C43044207","wikidata":"https://www.wikidata.org/wiki/Q618363","display_name":"Venous blood","level":2,"score":0.29319998621940613},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.2754000127315521},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.25619998574256897},{"id":"https://openalex.org/C2491326","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy homeostasis","level":3,"score":0.25279998779296875}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fped.2026.1935719","doi":"https://doi.org/10.3389/fped.2026.1935719","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1935719","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1935719/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13529971","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13529971/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13529971/pdf/fped-14-1935719.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Pediatr","raw_type":"Text"},{"id":"pmid:42682647","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42682647","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in pediatrics","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:9e21397c026e44d3955a8327fa43dc8f","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9e21397c026e44d3955a8327fa43dc8f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Pediatrics, Vol 14 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fped.2026.1935719","doi":"https://doi.org/10.3389/fped.2026.1935719","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fped.2026.1935719","pdf_url":"https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2026.1935719/pdf","source":{"id":"https://openalex.org/S2596117549","display_name":"Frontiers in Pediatrics","issn_l":"2296-2360","issn":["2296-2360"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Pediatrics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9907000064849854}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203669100.pdf","grobid_xml":"https://content.openalex.org/works/W7203669100.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W170233873","https://openalex.org/W2008283534","https://openalex.org/W2028817918","https://openalex.org/W2160234571","https://openalex.org/W2396402306","https://openalex.org/W2410812161","https://openalex.org/W3124597792","https://openalex.org/W3213968882","https://openalex.org/W4205744060","https://openalex.org/W4206283403","https://openalex.org/W4386878491","https://openalex.org/W4403563088","https://openalex.org/W4414961009"],"related_works":["https://openalex.org/W3216475639","https://openalex.org/W7098890933","https://openalex.org/W3047062448","https://openalex.org/W3174101841","https://openalex.org/W2477956331","https://openalex.org/W4398209846","https://openalex.org/W2401600137","https://openalex.org/W2082256420","https://openalex.org/W4411096434","https://openalex.org/W4385476198"],"abstract_inverted_index":{"Background":[0],"Phoenixin":[1],"is":[2],"a":[3,69,84,131,219,331],"novel":[4],"neuropeptide":[5],"encoded":[6],"by":[7,52,93,103,185],"the":[8,143,147,162,191],"SMIM20":[9],"gene,":[10],"implicated":[11],"in":[12,20,336,354],"energy":[13],"homeostasis":[14],"and":[15,33,43,65,80,91,128,139,149,164,182,245,284,311,319],"reproduction,":[16],"but":[17],"its":[18],"role":[19,333],"pediatric":[21,337,355],"metabolic":[22,313],"syndrome":[23,41,314],"remains":[24],"unknown.":[25],"Methods":[26],"This":[27],"cross-sectional":[28],"study":[29],"enrolled":[30],"98":[31],"children":[32,309],"adolescents":[34],"aged":[35],"7\u201318":[36],"years":[37],"[45":[38],"with":[39,45,230,310],"Metabolic":[40],"(MetS)":[42],"53":[44],"obesity":[46],"without":[47,312],"MetS].":[48],"MetS":[49,148,163,209,231],"was":[50,101,218],"defined":[51],"modified":[53],"International":[54],"Diabetes":[55],"Federation":[56],"criteria.":[57],"Biochemical":[58],"analyses":[59],"included":[60],"fasting":[61],"glucose,":[62],"lipid":[63],"profile,":[64],"liver":[66],"enzymes":[67],"on":[68,83,152],"Beckman":[70],"Coulter":[71],"AU5800":[72],"analyzer;":[73],"insulin,":[74],"cortisol,":[75],"adrenocorticotropic":[76],"hormone":[77],"(ACTH),":[78],"thyroid,":[79],"reproductive":[81],"hormones":[82],"Roche":[85],"Cobas":[86],"e601":[87],"electrochemiluminescence":[88],"immunoassay":[89],"system;":[90],"HbA1c":[92],"high-performance":[94],"liquid":[95],"chromatography":[96],"(Bio-Rad":[97],"D10).":[98],"Serum":[99,156],"phoenixin-14":[100,157,303,335,350],"quantified":[102],"sandwich":[104],"ELISA":[105],"(Bioassay":[106],"Technology":[107],"Laboratory":[108],"Cat.":[109],"No.":[110],"E7481Hu;":[111],"sensitivity":[112],"8.19":[113],"ng/L;":[114],"intra-assay":[115],"CV":[116,119],"6.8%,":[117],"interassay":[118],"9.2%).":[120],"Group":[121],"comparisons":[122],"were":[123,232],"performed":[124],"using":[125],"Mann\u2013Whitney":[126],"U":[127],"chi-square":[129],"tests;":[130],"general":[132],"linear":[133],"model":[134],"(GLM)":[135],"adjusting":[136,316],"for":[137,180,317,334],"age":[138,181,318],"Tanner":[140,183,216],"stage":[141,184,217,321],"assessed":[142],"independent":[144],"effect":[145],"of":[146],"obese":[150,165,308],"groups":[151,166],"serum":[153,302],"phoenixin-14.":[154],"Results":[155],"did":[158,304],"not":[159,305,329],"differ":[160,306],"between":[161,307],"(519.75":[167],"\u00b1":[168,172,235,239,260,264,274,278,288,292],"196.67":[169],"vs.":[170,212,237,251,262,276,290],"567.86":[171],"368.40":[173],"pg/mL;":[174,294],"p":[175,204,226,242,254,267,281,295,323],"=":[176,189,205,224,227,243,296,324],"0.955).":[177],"After":[178],"adjustment":[179],"GLM":[186],"(":[187,222,322],"n":[188],"95),":[190],"difference":[192],"remained":[193],"non-significant":[194],"(adjusted":[195],"difference:":[196],"\u221226.5":[197],"pg/mL,":[198],"95%":[199],"CI:":[200],"\u2212152.1":[201],"to":[202,347],"99.1;":[203],"0.676;":[206],"adjusted":[207],"means:":[208],"529.1":[210],"pg/mL":[211],"Obese":[213],"555.7":[214],"pg/mL).":[215],"significant":[220],"covariate":[221],"B":[223],"73.04,":[225],"0.009).":[228],"Children":[229],"older":[233],"(13.62":[234],"2.51":[236],"12.19":[238],"2.65":[240],"years;":[241],"0.010)":[244],"had":[246],"higher":[247,257,285],"median":[248],"insulin":[249],"(30.80":[250],"18.20":[252],"\u00b5IU/mL;":[253],"<":[255,268,282],"0.001),":[256,269,283],"triglycerides":[258],"(172.04":[259],"70.94":[261],"106.68":[263],"39.27":[265],"mg/dL;":[266,280],"lower":[270],"high-density":[271],"lipoprotein-cholesterol":[272],"(38.56":[273],"7.73":[275],"47.02":[277],"9.99":[279],"ACTH":[286],"(28.86":[287],"14.12":[289],"22.44":[291],"11.86":[293],"0.018).":[297],"Conclusions":[298],"In":[299],"this":[300],"cohort,":[301],"after":[315],"pubertal":[320],"0.676).":[325],"These":[326],"findings":[327],"do":[328],"support":[330],"discriminative":[332],"MetS.":[338],"Further":[339],"studies":[340],"including":[341],"healthy":[342],"normal-weight":[343],"controls":[344],"are":[345,352],"needed":[346],"determine":[348],"whether":[349],"concentrations":[351],"altered":[353],"obesity.":[356]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-08-19T00:00:00"}