{"id":"https://openalex.org/W7203653685","doi":"https://doi.org/10.64898/2026.08.16.745057","title":"Intracellular genomic variability driven by cellular compartmentalization in the giant bacterium Achromatium spp","display_name":"Intracellular genomic variability driven by cellular compartmentalization in the giant bacterium Achromatium spp","publication_year":2026,"publication_date":"2026-08-17","ids":{"openalex":"https://openalex.org/W7203653685","doi":"https://doi.org/10.64898/2026.08.16.745057"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.16.745057","doi":"https://doi.org/10.64898/2026.08.16.745057","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.16.745057","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/06/2026.08.16.745057.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/06/2026.08.16.745057.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013625127","display_name":"Danny Ionescu","orcid":"https://orcid.org/0000-0002-4658-8597","observed_orcids":["https://orcid.org/0000-0002-4658-8597"]},"institutions":[{"id":"https://openalex.org/I4210116314","display_name":"Leibniz Institute of Freshwater Ecology and Inland Fisheries","ror":"https://ror.org/01nftxb06","country_code":"DE","type":"facility","lineage":["https://openalex.org/I315704651","https://openalex.org/I4210116314"]},{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Danny Ionescu","raw_affiliation_strings":["Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","Department of Plankton and Microbial Ecology, Leibniz Institute of Freshwater Ecology and Inland Fisheries, Neuglobsow, Germany"],"raw_orcid":"https://orcid.org/0000-0002-4658-8597","affiliations":[{"raw_affiliation_string":"Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4577782"]},{"raw_affiliation_string":"Department of Plankton and Microbial Ecology, Leibniz Institute of Freshwater Ecology and Inland Fisheries, Neuglobsow, Germany","institution_ids":["https://openalex.org/I4210116314"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055496719","display_name":"Joana Mariz","orcid":"https://orcid.org/0000-0002-2209-8016","observed_orcids":["https://orcid.org/0000-0002-2209-8016"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Joana Mariz","raw_affiliation_strings":["Chair of Urban Water Systems Engineering, Technical University of Munich, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chair of Urban Water Systems Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147321976","display_name":"Kai Bukoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kai Bukoff","raw_affiliation_strings":["Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147362905","display_name":"Elene Tskitishvili","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Elene Tskitishvili","raw_affiliation_strings":["Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147335221","display_name":"Marit Gruener","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Marit Gr\u00fcner","raw_affiliation_strings":["Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157841592","display_name":"Laura Oroz Villegas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Laura Oroz Villegas","raw_affiliation_strings":["Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4577782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027001517","display_name":"Sophie-Luise Heidig","orcid":"https://orcid.org/0000-0002-2251-9060","observed_orcids":["https://orcid.org/0000-0002-2251-9060"]},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]},{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Sophie-Luise Heidig","raw_affiliation_strings":["Evolutionary Biology & Ecology, Universit\u00e9 libre de Bruxelles, Belgium","Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Belgium","Structural Biology Brussels, 3AI Lab, Vrije Universiteit Brussel, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-2251-9060","affiliations":[{"raw_affiliation_string":"Evolutionary Biology & Ecology, Universit\u00e9 libre de Bruxelles, Belgium","institution_ids":["https://openalex.org/I132053463"]},{"raw_affiliation_string":"Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Belgium","institution_ids":["https://openalex.org/I132053463"]},{"raw_affiliation_string":"Structural Biology Brussels, 3AI Lab, Vrije Universiteit Brussel, Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048994856","display_name":"Thomas Stach","orcid":"https://orcid.org/0000-0001-5461-9069","observed_orcids":["https://orcid.org/0000-0001-5461-9069"]},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Stach","raw_affiliation_strings":["Institute of Biology, Comparative Electron Microscopy, Humboldt University Berlin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0001-5461-9069","affiliations":[{"raw_affiliation_string":"Institute of Biology, Comparative Electron Microscopy, Humboldt University Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I39343248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087258300","display_name":"Julian Hennies","orcid":"https://orcid.org/0000-0002-0555-151X","observed_orcids":["https://orcid.org/0000-0002-0555-151X"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julian Hennies","raw_affiliation_strings":["EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0555-151X","affiliations":[{"raw_affiliation_string":"EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073308042","display_name":"Dietrich W. M. Walsh","orcid":"https://orcid.org/0000-0003-2067-1883","observed_orcids":["https://orcid.org/0000-0003-2067-1883"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dietrich Walsh","raw_affiliation_strings":["EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0003-2067-1883","affiliations":[{"raw_affiliation_string":"EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073658516","display_name":"Anna M. Steyer","orcid":"https://orcid.org/0000-0002-4814-7517","observed_orcids":["https://orcid.org/0000-0002-4814-7517"]},"institutions":[{"id":"https://openalex.org/I4210138560","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/03mstc592","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210153543","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anna M. Steyer","raw_affiliation_strings":["EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-4814-7517","affiliations":[{"raw_affiliation_string":"EMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany","institution_ids":["https://openalex.org/I4210138560","https://openalex.org/I4210153543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059826823","display_name":"Christian Wurzbacher","orcid":"https://orcid.org/0000-0001-7418-0831","observed_orcids":["https://orcid.org/0000-0001-7418-0831"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Wurzbacher","raw_affiliation_strings":["Chair of Urban Water Systems Engineering, Technical University of Munich, Garching, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7418-0831","affiliations":[{"raw_affiliation_string":"Chair of Urban Water Systems Engineering, Technical University of Munich, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014599823","display_name":"Mina Bi\u017ei\u0107","orcid":"https://orcid.org/0000-0002-6870-4018","observed_orcids":["https://orcid.org/0000-0002-6870-4018"]},"institutions":[{"id":"https://openalex.org/I4577782","display_name":"Technische Universit\u00e4t Berlin","ror":"https://ror.org/03v4gjf40","country_code":"DE","type":"education","lineage":["https://openalex.org/I4577782"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mina Bizic","raw_affiliation_strings":["Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-6870-4018","affiliations":[{"raw_affiliation_string":"Department of Environmental Microbiomics, Technische Universit\u00e4t Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4577782"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5013625127"],"corresponding_institution_ids":["https://openalex.org/I4210116314","https://openalex.org/I4577782"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.5708000063896179,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.5708000063896179,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.27559998631477356,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.06610000133514404,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyploidy","display_name":"polyploidy","score":0.7549999952316284},{"id":"https://openalex.org/keywords/cellular-compartmentalization","display_name":"cellular compartmentalization","score":0.7480000257492065},{"id":"https://openalex.org/keywords/chromosome-inheritance","display_name":"chromosome inheritance","score":0.6809999942779541},{"id":"https://openalex.org/keywords/bacterial-genome-evolution","display_name":"bacterial genome evolution","score":0.6499999761581421},{"id":"https://openalex.org/keywords/cellular-architecture","display_name":"cellular architecture","score":0.5040000081062317},{"id":"https://openalex.org/keywords/homologous-recombination","display_name":"homologous recombination","score":0.7260000109672546}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.855400025844574},{"id":"https://openalex.org/C2776626444","wikidata":"https://www.wikidata.org/wiki/Q213410","display_name":"Polyploid","level":4,"score":0.7263000011444092},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6388000249862671},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6101999878883362},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.5277000069618225},{"id":"https://openalex.org/C64894306","wikidata":"https://www.wikidata.org/wiki/Q849622","display_name":"Homologous chromosome","level":3,"score":0.4115000069141388},{"id":"https://openalex.org/C110455231","wikidata":"https://www.wikidata.org/wiki/Q897788","display_name":"Compartmentalization (fire protection)","level":3,"score":0.36820000410079956},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.35670000314712524},{"id":"https://openalex.org/C174600577","wikidata":"https://www.wikidata.org/wiki/Q5533491","display_name":"Genome evolution","level":4,"score":0.34150001406669617},{"id":"https://openalex.org/C2778354886","wikidata":"https://www.wikidata.org/wiki/Q5113927","display_name":"Chromosome segregation","level":4,"score":0.32339999079704285},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.314300000667572},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.3050999939441681},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.3018999993801117},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.3009999990463257},{"id":"https://openalex.org/C58167604","wikidata":"https://www.wikidata.org/wiki/Q5121654","display_name":"Circular bacterial chromosome","level":4,"score":0.29490000009536743},{"id":"https://openalex.org/C22322919","wikidata":"https://www.wikidata.org/wiki/Q5533501","display_name":"Genomic organization","level":4,"score":0.2896000146865845},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C153726182","wikidata":"https://www.wikidata.org/wiki/Q3720909","display_name":"Intracellular parasite","level":3,"score":0.27869999408721924},{"id":"https://openalex.org/C61271108","wikidata":"https://www.wikidata.org/wiki/Q3180866","display_name":"Genome size","level":4,"score":0.2752000093460083},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.27410000562667847},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.2655999958515167},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.26179999113082886},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.26010000705718994},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.2533999979496002},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2524999976158142}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.08.16.745057","doi":"https://doi.org/10.64898/2026.08.16.745057","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.16.745057","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/06/2026.08.16.745057.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.08.16.745057","doi":"https://doi.org/10.64898/2026.08.16.745057","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.16.745057","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/06/2026.08.16.745057.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8007594696","display_name":"\u00d6koevolution und zellul\u00e4re Funktionalit\u00e4t der heterozygoten Bakteriengattung Achromatium","funder_award_id":"465407921","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320314023","display_name":"European Molecular Biology Laboratory","ror":"https://ror.org/050589e39"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320325136","display_name":"Boehringer Ingelheim Stiftung","ror":"https://ror.org/03tx8dq56"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203653685.pdf","grobid_xml":"https://content.openalex.org/works/W7203653685.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1665822751","https://openalex.org/W1971819844","https://openalex.org/W1976358931","https://openalex.org/W2008563521","https://openalex.org/W2008919704","https://openalex.org/W2013737863","https://openalex.org/W2024661139","https://openalex.org/W2045716211","https://openalex.org/W2087684120","https://openalex.org/W2109636763","https://openalex.org/W2120902911","https://openalex.org/W2131271579","https://openalex.org/W2133431912","https://openalex.org/W2143485490","https://openalex.org/W2151103935","https://openalex.org/W2157281025","https://openalex.org/W2166669307","https://openalex.org/W2429289397","https://openalex.org/W2579374544","https://openalex.org/W2625146699","https://openalex.org/W2751131112","https://openalex.org/W2911038318","https://openalex.org/W2938868597","https://openalex.org/W2940163581","https://openalex.org/W2941777578","https://openalex.org/W2951254987","https://openalex.org/W2997128986","https://openalex.org/W3005087090","https://openalex.org/W3099678413","https://openalex.org/W3127648756","https://openalex.org/W3135337986","https://openalex.org/W3158874674","https://openalex.org/W4241167997","https://openalex.org/W4283327986","https://openalex.org/W4304481015","https://openalex.org/W4386726959","https://openalex.org/W4394987863","https://openalex.org/W4406621639","https://openalex.org/W7096332473"],"related_works":["https://openalex.org/W4210651490","https://openalex.org/W2751131112","https://openalex.org/W3099678413","https://openalex.org/W2018173752","https://openalex.org/W2164894674","https://openalex.org/W2503418844","https://openalex.org/W2495169411","https://openalex.org/W2130465193","https://openalex.org/W2409983430","https://openalex.org/W2761423099"],"abstract_inverted_index":{"Abstract":[0],"Bacteria":[1],"of":[2,8,42,59,73,94,107,127,147],"the":[3,52,90,104,111,143],"genus":[4],"Achromatium":[5,95],"harbor":[6],"hundreds":[7],"chromosomes":[9,28],"that":[10,27,64,98],"were":[11],"previously":[12,75],"suggested":[13],"to":[14],"be":[15],"genetically":[16],"diverse.":[17],"By":[18],"sequencing":[19,84],"multiple":[20],"regions":[21],"from":[22,103],"individual":[23],"cells,":[24],"we":[25,88],"demonstrate":[26],"within":[29],"a":[30,71,125,140],"single":[31],"cell":[32],"differ":[33],"in":[34,80,130,151],"nucleotide":[35],"and":[36,50,96,134,145],"amino":[37],"acid":[38],"sequence,":[39],"reaching":[40],"levels":[41],"divergence":[43],"well":[44],"below":[45,51],"accepted":[46],"bacterial":[47],"species":[48],"boundaries":[49],"range":[53],"associated":[54,76],"with":[55,77,85],"homologous":[56],"recombination.":[57,118],"Sequencing":[58],"dividing":[60],"cells":[61,66],"further":[62],"revealed":[63],"daughter":[65],"inherit":[67],"distinct":[68],"chromosome":[69,108,149],"populations,":[70],"mode":[72],"inheritance":[74,146],"sexual":[78],"reproduction":[79],"eukaryotes.":[81],"Combining":[82],"subcellular":[83],"high-resolution":[86],"microscopy,":[87],"reconstruct":[89],"three-dimensional":[91],"cellular":[92,122],"architecture":[93,123],"show":[97],"extensive":[99],"intracellular":[100],"heterogeneity":[101],"arises":[102],"spatial":[105,136],"segregation":[106,138],"populations":[109,150],"by":[110],"cell\u2019s":[112],"internal":[113],"structure,":[114],"which":[115],"limits":[116],"genome-wide":[117],"Our":[119],"findings":[120],"establish":[121],"as":[124,139],"determinant":[126],"genome":[128,137],"evolution":[129],"giant":[131],"polyploid":[132],"bacteria":[133],"identify":[135],"mechanism":[141],"enabling":[142],"maintenance":[144],"divergent":[148],"bacteria.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-18T00:00:00"}