{"id":"https://openalex.org/W7203598736","doi":"https://doi.org/10.64898/2026.08.11.744301","title":"The engagement of layer 6 corticothalamic neurons in somatosensation","display_name":"The engagement of layer 6 corticothalamic neurons in somatosensation","publication_year":2026,"publication_date":"2026-08-17","ids":{"openalex":"https://openalex.org/W7203598736","doi":"https://doi.org/10.64898/2026.08.11.744301","pmid":"https://pubmed.ncbi.nlm.nih.gov/42856142","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13648358"},"language":"en","primary_location":{"id":"doi:10.64898/2026.08.11.744301","doi":"https://doi.org/10.64898/2026.08.11.744301","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.11.744301","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/04/2026.08.11.744301.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/04/2026.08.11.744301.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087924354","display_name":"Elaida D. Dimwamwa","orcid":"https://orcid.org/0000-0002-6191-1524","observed_orcids":["https://orcid.org/0000-0002-6191-1524"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elaida D Dimwamwa","raw_affiliation_strings":["Center for Neural Science, New York University, New York, NY","Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA"],"raw_orcid":"https://orcid.org/0000-0002-6191-1524","affiliations":[{"raw_affiliation_string":"Center for Neural Science, New York University, New York, NY","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043316257","display_name":"Nelson Chang","orcid":"https://orcid.org/0009-0004-2701-0484","observed_orcids":["https://orcid.org/0009-0004-2701-0484"]},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nelson H Chang","raw_affiliation_strings":["Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074305269","display_name":"Christian Waiblinger","orcid":"https://orcid.org/0000-0002-9763-3693","observed_orcids":["https://orcid.org/0000-0002-9763-3693"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian Waiblinger","raw_affiliation_strings":["Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045444914","display_name":"Garrett B. Stanley","orcid":"https://orcid.org/0000-0003-2039-7706","observed_orcids":["https://orcid.org/0000-0003-2039-7706"]},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]},{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I2802612298","display_name":"The Wallace H. Coulter Department of Biomedical Engineering","ror":"https://ror.org/02j15s898","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Garrett B Stanley","raw_affiliation_strings":["Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA"],"raw_orcid":"https://orcid.org/0000-0003-2039-7706","affiliations":[{"raw_affiliation_string":"Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA","institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5045444914"],"corresponding_institution_ids":["https://openalex.org/I130701444","https://openalex.org/I150468666","https://openalex.org/I2802612298"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.875,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.875,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10914","display_name":"Tactile and Sensory Interactions","score":0.04500000178813934,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.03200000151991844,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/somatosensation","display_name":"somatosensory perception","score":0.8539999723434448},{"id":"https://openalex.org/keywords/thalamocortical-circuits","display_name":"thalamocortical circuits","score":0.9139999747276306},{"id":"https://openalex.org/keywords/tactile-detection","display_name":"tactile detection","score":0.7409999966621399},{"id":"https://openalex.org/keywords/sensory-coding","display_name":"sensory coding","score":0.6729999780654907},{"id":"https://openalex.org/keywords/gain-modulation","display_name":"gain modulation","score":0.718999981880188},{"id":"https://openalex.org/keywords/thalamus","display_name":"thalamus","score":0.6209999918937683},{"id":"https://openalex.org/keywords/primary-sensory-cortex","display_name":"primary sensory cortex","score":0.8389999866485596},{"id":"https://openalex.org/keywords/behavior-prediction","display_name":"behavior prediction","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.8453999757766724},{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.8202000260353088},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.7797999978065491},{"id":"https://openalex.org/C2779246727","wikidata":"https://www.wikidata.org/wiki/Q184215","display_name":"Thalamus","level":2,"score":0.6973999738693237},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.6015999913215637},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.5103999972343445},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.47600001096725464},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.3400999903678894},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33660000562667847},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.328000009059906},{"id":"https://openalex.org/C19071747","wikidata":"https://www.wikidata.org/wiki/Q1755207","display_name":"Receptive field","level":2,"score":0.3208000063896179},{"id":"https://openalex.org/C2983650178","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cortical neurons","level":2,"score":0.3176000118255615},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.31610000133514404},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.3127000033855438},{"id":"https://openalex.org/C2780196419","wikidata":"https://www.wikidata.org/wiki/Q1762173","display_name":"Nerve net","level":2,"score":0.3098999857902527},{"id":"https://openalex.org/C2776861996","wikidata":"https://www.wikidata.org/wiki/Q241849","display_name":"Sensory processing","level":3,"score":0.29330000281333923},{"id":"https://openalex.org/C25457674","wikidata":"https://www.wikidata.org/wiki/Q17163316","display_name":"Sensory stimulation therapy","level":3,"score":0.27309998869895935},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C66746571","wikidata":"https://www.wikidata.org/wiki/Q1134833","display_name":"ENCODE","level":3,"score":0.2678999900817871},{"id":"https://openalex.org/C2775908076","wikidata":"https://www.wikidata.org/wiki/Q3142126","display_name":"Sensory neuron","level":3,"score":0.25589999556541443}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.64898/2026.08.11.744301","doi":"https://doi.org/10.64898/2026.08.11.744301","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.11.744301","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/04/2026.08.11.744301.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:42856142","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42856142","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13648358","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13648358/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.64898/2026.08.11.744301","doi":"https://doi.org/10.64898/2026.08.11.744301","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.08.11.744301","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/10/04/2026.08.11.744301.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4607870367","display_name":"Thalamocortical state control of tactile sensing: Mechanisms, Models, and Behavior","funder_award_id":"R01NS104928","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5280230945","display_name":"Feedback and feedforward gating of sensory signaling through timing in the thalamocortical loop","funder_award_id":"RF1NS128896","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203598736.pdf","grobid_xml":"https://content.openalex.org/works/W7203598736.grobid-xml"},"referenced_works_count":81,"referenced_works":["https://openalex.org/W1518805832","https://openalex.org/W1519578210","https://openalex.org/W1895775718","https://openalex.org/W1965680943","https://openalex.org/W1967857491","https://openalex.org/W1979258934","https://openalex.org/W1984202832","https://openalex.org/W1987261355","https://openalex.org/W1987332330","https://openalex.org/W1991180842","https://openalex.org/W1994955957","https://openalex.org/W1996889564","https://openalex.org/W1996938738","https://openalex.org/W1999134832","https://openalex.org/W2001830985","https://openalex.org/W2008477366","https://openalex.org/W2012509205","https://openalex.org/W2017400430","https://openalex.org/W2021271087","https://openalex.org/W2032773159","https://openalex.org/W2035753658","https://openalex.org/W2041918412","https://openalex.org/W2045933100","https://openalex.org/W2047125044","https://openalex.org/W2049040467","https://openalex.org/W2049894354","https://openalex.org/W2055145256","https://openalex.org/W2059585285","https://openalex.org/W2071500241","https://openalex.org/W2087235763","https://openalex.org/W2089653659","https://openalex.org/W2099984553","https://openalex.org/W2103113084","https://openalex.org/W2109062476","https://openalex.org/W2111347940","https://openalex.org/W2112575206","https://openalex.org/W2117647464","https://openalex.org/W2121238618","https://openalex.org/W2139778447","https://openalex.org/W2143988681","https://openalex.org/W2161938991","https://openalex.org/W2163492988","https://openalex.org/W2182744216","https://openalex.org/W2246750919","https://openalex.org/W2284889964","https://openalex.org/W2317325433","https://openalex.org/W2411237684","https://openalex.org/W2429753743","https://openalex.org/W2565971026","https://openalex.org/W2625138568","https://openalex.org/W2735725811","https://openalex.org/W2781966430","https://openalex.org/W2789919621","https://openalex.org/W2801704011","https://openalex.org/W2904949961","https://openalex.org/W2911773783","https://openalex.org/W2921338417","https://openalex.org/W2985062680","https://openalex.org/W3029211407","https://openalex.org/W3076806110","https://openalex.org/W3095081349","https://openalex.org/W3109155306","https://openalex.org/W3157335290","https://openalex.org/W3161508021","https://openalex.org/W3163059484","https://openalex.org/W3204721145","https://openalex.org/W3211354089","https://openalex.org/W4220887442","https://openalex.org/W4225634426","https://openalex.org/W4225679510","https://openalex.org/W4284698454","https://openalex.org/W4286492481","https://openalex.org/W4317477839","https://openalex.org/W4378070205","https://openalex.org/W4388823868","https://openalex.org/W4394577481","https://openalex.org/W4395478479","https://openalex.org/W4407367904","https://openalex.org/W4414084665","https://openalex.org/W4416744931","https://openalex.org/W7140237660"],"related_works":["https://openalex.org/W4388958645","https://openalex.org/W3166926986","https://openalex.org/W4388958695","https://openalex.org/W2091111430","https://openalex.org/W4395478479","https://openalex.org/W4400061058","https://openalex.org/W3210649068","https://openalex.org/W3040667808","https://openalex.org/W3076806110","https://openalex.org/W2625138568"],"abstract_inverted_index":{"ABSTRACT":[0],"The":[1],"corticothalamic":[2,203,314],"neurons":[3,48,56,98,120,127,162,183,205,237,287],"from":[4,213],"layer":[5],"6":[6,202],"(L6CT)":[7,204],"of":[8,40,46,61,67,82,108,119,134,143,151,165,190,196,208,246,254,305],"primary":[9],"sensory":[10,63,104,117,136,215,228,259,294,306],"cortices":[11],"provide":[12,158,206],"extensive":[13],"input":[14],"to":[15,20,27,70,113,115,184,217,223],"the":[16,38,68,80,93,102,106,116,122,130,144,149,175,191,197,209,214,218,221,244,267,270,300],"thalamus":[17],"in":[18,33,79,92,177,186,227,238,317],"addition":[19],"projecting":[21],"across":[22],"layers":[23],"intracortically,":[24],"positioning":[25],"them":[26],"play":[28],"a":[29,135,169,258],"key":[30],"hypothesized":[31],"role":[32,226],"shaping":[34],"thalamocortical":[35,62,123],"signaling.":[36],"With":[37],"expansion":[39],"tools":[41],"for":[42,160,291,298],"precise":[43],"functional":[44,194],"identification":[45],"L6CT":[47,55,97,126,161,182,236,286],"during":[49,168],"in-vivo":[50],"electrophysiology,":[51],"increasing":[52],"evidence":[53,159],"highlights":[54],"as":[57,163],"dynamic":[58],"gain":[59],"modulators":[60],"responses.":[64],"However,":[65],"much":[66],"work":[69],"date":[71],"has":[72],"been":[73],"conducted":[74],"under":[75],"anesthesia":[76],"and":[77,272,296,302,312],"not":[78],"context":[81],"awake":[83,94],"and/or":[84],"behaving":[85],"animals.":[86],"In":[87],"this":[88,178],"study,":[89],"we":[90,156],"show":[91,234],"mouse":[95,239],"that":[96,235,285],"convey":[99],"information":[100],"about":[101],"ascending":[103],"input,":[105],"timing":[107],"which":[109,224],"is":[110],"fast":[111],"enough":[112],"contribute":[114],"response":[118],"throughout":[121],"circuit.":[124],"Overall,":[125],"robustly":[128,242],"encode":[129],"presence":[131,245],"vs":[132],"absence":[133],"stimulus":[137,255,271],"but":[138,249],"are":[139,250,288],"relatively":[140],"weak":[141,252],"encoders":[142,253],"fine":[145,293],"details.":[146],"Benchmarked":[147],"against":[148],"activity":[150],"other":[152,278],"excitatory":[153,280],"cortical":[154,279],"neurons,":[155],"also":[157],"predictors":[164],"behavioral":[166,274,303],"outcome":[167,275],"trained":[170],"detection":[171,260],"task.":[172],"Taken":[173],"together,":[174],"results":[176],"study":[179],"potentially":[180],"tie":[181],"behavior":[185],"tactile":[187,247],"detection,":[188],"one":[189,207],"most":[192],"fundamental":[193],"roles":[195],"pathway.":[198],"Significance":[199],"Statement":[200],"Layer":[201],"major":[210],"feedback":[211,315],"pathways":[212],"cortex":[216,241],"thalamus,":[219],"yet":[220],"extent":[222],"their":[225,262],"processing":[229],"remains":[230],"poorly":[231],"understood.":[232],"We":[233],"somatosensory":[240],"signal":[243],"stimuli":[248],"comparatively":[251],"strength.":[256],"During":[257],"task,":[261],"responses":[263],"strongly":[264],"reflect":[265],"whether":[266],"animal":[268],"detects":[269],"predict":[273],"better":[276],"than":[277],"neurons.":[281],"These":[282],"findings":[283],"suggest":[284],"specialized":[289],"less":[290],"representing":[292],"detail":[295],"more":[297],"signaling":[299],"occurrence":[301],"relevance":[304],"events,":[307],"providing":[308],"insight":[309],"into":[310],"when":[311],"how":[313],"participates":[316],"perception.":[318]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-18T00:00:00"}
