{"id":"https://openalex.org/W7203483961","doi":"https://doi.org/10.1109/icosaas68663.2026.11648837","title":"A Novel Adaptive Neuro-Gradient Model for Accurate Lupus Disease Detection using Intelligent Feature Optimization","display_name":"A Novel Adaptive Neuro-Gradient Model for Accurate Lupus Disease Detection using Intelligent Feature Optimization","publication_year":2026,"publication_date":"2026-07-01","ids":{"openalex":"https://openalex.org/W7203483961","doi":"https://doi.org/10.1109/icosaas68663.2026.11648837"},"language":"en","primary_location":{"id":"doi:10.1109/icosaas68663.2026.11648837","doi":"https://doi.org/10.1109/icosaas68663.2026.11648837","is_oa":true,"landing_page_url":"https://doi.org/10.1109/icosaas68663.2026.11648837","pdf_url":null,"source":{"id":"https://openalex.org/S7407096249","display_name":"International Conference on Intelligent and Sustainable AI Systems (ICOSAAS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2026 International Conference on Intelligent and Sustainable AI Systems (ICOSAAS)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1109/icosaas68663.2026.11648837","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5119103291","display_name":"Flemitha Mary D","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I85461943","display_name":"Saveetha University","ror":"https://ror.org/0034me914","country_code":"IN","type":"education","lineage":["https://openalex.org/I85461943"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Flemitha Mary D","raw_affiliation_strings":["Saveetha Institute of Medical and Technical Sciences (SIMATS)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saveetha Institute of Medical and Technical Sciences (SIMATS)","institution_ids":["https://openalex.org/I85461943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070253642","display_name":"G. Ramkumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I85461943","display_name":"Saveetha University","ror":"https://ror.org/0034me914","country_code":"IN","type":"education","lineage":["https://openalex.org/I85461943"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Govindaraj Ramkumar","raw_affiliation_strings":["Saveetha Institute of Medical and Technical Sciences (SIMATS)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saveetha Institute of Medical and Technical Sciences (SIMATS)","institution_ids":["https://openalex.org/I85461943"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I85461943"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.53936545,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1183","last_page":"1188"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.4636000096797943,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.4636000096797943,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.3434999883174896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.18119999766349792,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9940000176429749},{"id":"https://openalex.org/keywords/disease-detection","display_name":"disease detection","score":0.7200000286102295},{"id":"https://openalex.org/keywords/feature-optimization","display_name":"feature optimization","score":0.718999981880188},{"id":"https://openalex.org/keywords/gene-expression-data","display_name":"gene expression data","score":0.9789999723434448},{"id":"https://openalex.org/keywords/dimensionality-reduction","display_name":"dimensionality reduction","score":0.9549999833106995},{"id":"https://openalex.org/keywords/autoimmune-disease-diagnosis","display_name":"autoimmune disease diagnosis","score":0.8510000109672546},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6560999751091003},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5871999859809875},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5214999914169312},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5170999765396118},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.3467000126838684},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.31380000710487366},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.29490000009536743},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.2847000062465668},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.2824000120162964},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.27059999108314514},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.25}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/icosaas68663.2026.11648837","doi":"https://doi.org/10.1109/icosaas68663.2026.11648837","is_oa":true,"landing_page_url":"https://doi.org/10.1109/icosaas68663.2026.11648837","pdf_url":null,"source":{"id":"https://openalex.org/S7407096249","display_name":"International Conference on Intelligent and Sustainable AI Systems (ICOSAAS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2026 International Conference on Intelligent and Sustainable AI Systems (ICOSAAS)","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.1109/icosaas68663.2026.11648837","doi":"https://doi.org/10.1109/icosaas68663.2026.11648837","is_oa":true,"landing_page_url":"https://doi.org/10.1109/icosaas68663.2026.11648837","pdf_url":null,"source":{"id":"https://openalex.org/S7407096249","display_name":"International Conference on Intelligent and Sustainable AI Systems (ICOSAAS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2026 International Conference on Intelligent and Sustainable AI Systems (ICOSAAS)","raw_type":"proceedings-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W4381683768","https://openalex.org/W4388585079","https://openalex.org/W4388777516","https://openalex.org/W4389440544","https://openalex.org/W4390605262","https://openalex.org/W4394996651","https://openalex.org/W4399953431","https://openalex.org/W4402515295","https://openalex.org/W4404538642","https://openalex.org/W4409103323","https://openalex.org/W4415708340","https://openalex.org/W4415827681","https://openalex.org/W7155414543"],"related_works":["https://openalex.org/W7203447719","https://openalex.org/W7203475861","https://openalex.org/W7159778310","https://openalex.org/W7129353199","https://openalex.org/W7167022123","https://openalex.org/W7203474680","https://openalex.org/W6903639251","https://openalex.org/W4404768679","https://openalex.org/W4380184406","https://openalex.org/W7160089761"],"abstract_inverted_index":{"The":[0,74,102],"systemic":[1],"Lupus":[2],"Erythematosus":[3],"is":[4,12,76,106,118,121,153,175],"a":[5,58,89,143,160,176],"heterogeneous":[6,19],"and":[7,21,39,87,115,142,150,178,184],"multifaceted":[8],"autoimmune":[9],"disease,":[10],"which":[11],"challenging":[13],"to":[14,33,50,69,96,166,181],"diagnose,":[15],"because":[16],"of":[17,36,41,67,93,100,104,112,140,146,187],"the":[18,22,98,110,125,134,157,170,172,182,188],"symptoms":[20],"high-dimensional":[23],"biological":[24],"data.":[25],"Conventional":[26],"machine":[27],"learning":[28,91],"methods":[29],"would":[30],"also":[31,154],"tend":[32],"have":[34],"redundancy":[35],"features,":[37,86],"noise,":[38],"lack":[40],"flexibility":[42],"hence":[43],"less":[44],"diagnostic":[45],"performance.":[46],"In":[47],"this":[48,54],"regard,":[49],"overcome":[51],"these":[52],"constraints,":[53],"paper":[55],"will":[56],"present":[57],"new":[59],"Adaptive":[60],"Neuro-Gradient":[61],"Model":[62],"coupled":[63],"with":[64],"intelligent":[65],"optimization":[66,114],"features":[68],"help":[70],"detect":[71],"lupus":[72,189],"disease.":[73,190],"methodology":[75],"aimed":[77],"at":[78],"processing":[79],"gene":[80],"expression":[81],"data,":[82],"identifying":[83],"most":[84],"informative":[85],"using":[88],"gradient-based":[90],"mechanism":[92],"neural":[94],"type":[95],"improve":[97],"accuracy":[99,139],"classification.":[101],"dimensionality":[103],"data":[105],"greatly":[107],"minimized":[108],"in":[109],"process":[111],"feature":[113],"information":[116],"that":[117,133,156],"very":[119],"important":[120],"maintained":[122],"thus":[123],"enhancing":[124],"computational":[126],"efficiency.":[127],"It":[128,152],"has":[129,137,159],"been":[130],"experimentally":[131],"proven":[132],"proposed":[135],"model":[136,158],"an":[138],"96%,":[141],"high":[144],"level":[145],"precision,":[147],"recall,":[148],"F1-score,":[149],"AUC.":[151],"demonstrated":[155],"better":[161],"generalization":[162],"ability":[163],"as":[164],"compared":[165],"other":[167],"approaches.":[168],"On":[169],"whole,":[171],"framework":[173],"suggested":[174],"valid":[177],"effective":[179],"approach":[180],"early":[183],"precise":[185],"identification":[186]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-08-15T00:00:00"}