{"id":"https://openalex.org/W7203478805","doi":"https://doi.org/10.1016/j.celrep.2026.117698","title":"Synovial lining macrophages form during early postnatal life via fetal-derived CX3CR1+ cells and AQP1+ intermediates","display_name":"Synovial lining macrophages form during early postnatal life via fetal-derived CX3CR1+ cells and AQP1+ intermediates","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7203478805","doi":"https://doi.org/10.1016/j.celrep.2026.117698","pmid":"https://pubmed.ncbi.nlm.nih.gov/42603276"},"language":"en","primary_location":{"id":"doi:10.1016/j.celrep.2026.117698","doi":"https://doi.org/10.1016/j.celrep.2026.117698","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2026.117698","pdf_url":null,"source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.celrep.2026.117698","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5147140986","display_name":"Marl\u00e8ne S. Magalhaes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Marlene Magalhaes Pinto","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053441669","display_name":"Bert Malengier\u2010Devlies","orcid":"https://orcid.org/0000-0003-3527-1145","observed_orcids":["https://orcid.org/0000-0003-3527-1145"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bert Malengier-Devlies","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047149790","display_name":"Guillaume Seuzaret","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Guillaume Seuzaret","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000607389","display_name":"Anna Ahlback","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna Ahlback","raw_affiliation_strings":["University of Glasgow;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Glasgow;","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107052701","display_name":"Solvig Becker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Solvig Becker","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106884359","display_name":"Katelyn Patatsos","orcid":"https://orcid.org/0000-0001-9980-8349","observed_orcids":["https://orcid.org/0000-0001-9980-8349"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Katelyn Patatsos","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117701420","display_name":"Georgios Drakoulis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Georgios Drakoulis","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029393940","display_name":"Julia Karjalainen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julia Karjalainen","raw_affiliation_strings":["University of Oxford;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford;","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020459762","display_name":"Christiane Ruedl","orcid":"https://orcid.org/0000-0002-5599-6541","observed_orcids":["https://orcid.org/0000-0002-5599-6541"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Christiane Ruedl","raw_affiliation_strings":["Singapore National University;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Singapore National University;","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052806458","display_name":"David Voehringer","orcid":"https://orcid.org/0000-0001-6650-0639","observed_orcids":["https://orcid.org/0000-0001-6650-0639"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Voehringer","raw_affiliation_strings":["University of Erlangen;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Erlangen;","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063357947","display_name":"Calum C. Bain","orcid":"https://orcid.org/0000-0001-8884-327X","observed_orcids":["https://orcid.org/0000-0001-8884-327X"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Calum C Bain","raw_affiliation_strings":["University of Glasgow;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Glasgow;","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044952739","display_name":"Elaine Emmerson","orcid":"https://orcid.org/0000-0002-5902-3368","observed_orcids":["https://orcid.org/0000-0002-5902-3368"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elaine Emmerson","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078020780","display_name":"Barbora Schonfeldova","orcid":"https://orcid.org/0000-0002-7114-9780","observed_orcids":["https://orcid.org/0000-0002-7114-9780"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4405264228","display_name":"Kennedy Institute of Rheumatology","ror":"https://ror.org/01ahsqc77","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Barbora Schonfeldova","raw_affiliation_strings":["The Kennedy Institute of Rheumatology, University of Oxford;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Kennedy Institute of Rheumatology, University of Oxford;","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012706835","display_name":"Kristina Zec","orcid":"https://orcid.org/0000-0003-1005-2368","observed_orcids":["https://orcid.org/0000-0003-1005-2368"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kristina Zec","raw_affiliation_strings":["University of Oxford;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford;","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081801802","display_name":"Irina A. Udalova","orcid":"https://orcid.org/0000-0002-6716-2528","observed_orcids":["https://orcid.org/0000-0002-6716-2528"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Irina Udalova","raw_affiliation_strings":["University of Oxford;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford;","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016496358","display_name":"Theodoros Simakou","orcid":"https://orcid.org/0000-0002-0839-6383","observed_orcids":["https://orcid.org/0000-0002-0839-6383"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Theodoros Simakou","raw_affiliation_strings":["University of Glasgow;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Glasgow;","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125131359","display_name":"Lucy MacDonald","orcid":"https://orcid.org/0000-0001-7727-3873","observed_orcids":["https://orcid.org/0000-0001-7727-3873"]},"institutions":[{"id":"https://openalex.org/I4210117448","display_name":"Arthritis UK","ror":"https://ror.org/02jkpm469","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210117448"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lucy MacDonald","raw_affiliation_strings":["Research into Inflammatory Arthritis Centre Versus Arthritis (RACE), Glasgow, Birmingham, Newcastle,;"],"raw_orcid":"https://orcid.org/0000-0001-7727-3873","affiliations":[{"raw_affiliation_string":"Research into Inflammatory Arthritis Centre Versus Arthritis (RACE), Glasgow, Birmingham, Newcastle,;","institution_ids":["https://openalex.org/I4210117448"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052191975","display_name":"Mariola Kurowska\u2010Stolarska","orcid":"https://orcid.org/0000-0003-2124-7777","observed_orcids":["https://orcid.org/0000-0003-2124-7777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mariola Kurowska-Stolarska","raw_affiliation_strings":["Institute of Infection, Immunity and Inflammation;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Infection, Immunity and Inflammation;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016406517","display_name":"Jadwiga Miotla\u2010Zarebska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4405264228","display_name":"Kennedy Institute of Rheumatology","ror":"https://ror.org/01ahsqc77","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jadwiga Zarebska","raw_affiliation_strings":["Kennedy InsNtute of Rheumatology , University of Oxford , UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kennedy InsNtute of Rheumatology , University of Oxford , UK","institution_ids":["https://openalex.org/I40120149","https://openalex.org/I4405264228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139460832","display_name":"Tonia Vincent","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tonia Vincent","raw_affiliation_strings":["University of Oxford;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Oxford;","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044587619","display_name":"Rom\u00e9o Ricci","orcid":"https://orcid.org/0000-0002-9766-4369","observed_orcids":["https://orcid.org/0000-0002-9766-4369"]},"institutions":[{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Romeo Ricci","raw_affiliation_strings":["IGBMC;"],"raw_orcid":"https://orcid.org/0000-0002-9766-4369","affiliations":[{"raw_affiliation_string":"IGBMC;","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019661080","display_name":"Eric Erbs","orcid":"https://orcid.org/0009-0008-6447-7154","observed_orcids":["https://orcid.org/0009-0008-6447-7154"]},"institutions":[{"id":"https://openalex.org/I4210086872","display_name":"Institut de g\u00e9n\u00e9tique et de biologie mol\u00e9culaire et cellulaire","ror":"https://ror.org/0015ws592","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210086872","https://openalex.org/I4210096427","https://openalex.org/I68947357"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Eric Erbs","raw_affiliation_strings":["IGBMC;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IGBMC;","institution_ids":["https://openalex.org/I4210086872"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088815756","display_name":"Jack Barrington","orcid":"https://orcid.org/0000-0002-4554-6037","observed_orcids":["https://orcid.org/0000-0002-4554-6037"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jack Barrington","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051903567","display_name":"Barry W. McColl","orcid":"https://orcid.org/0000-0002-0521-9656","observed_orcids":["https://orcid.org/0000-0002-0521-9656"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Barry W McColl","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":"https://orcid.org/0000-0002-0521-9656","affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087291004","display_name":"Georgiana Neag","orcid":"https://orcid.org/0000-0002-3087-867X","observed_orcids":["https://orcid.org/0000-0002-3087-867X"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Georgiana Neag","raw_affiliation_strings":["University of Birmingham;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Birmingham;","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010528606","display_name":"Samuel Kemble","orcid":"https://orcid.org/0000-0002-3359-7718","observed_orcids":["https://orcid.org/0000-0002-3359-7718"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Samuel Kemble","raw_affiliation_strings":["University Birmingham;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Birmingham;","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160399815","display_name":"Christopher Mahony","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christopher Mahony","raw_affiliation_strings":["University of Birmingham;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Birmingham;","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070393812","display_name":"Adam P. Croft","orcid":"https://orcid.org/0000-0002-9487-0511","observed_orcids":["https://orcid.org/0000-0002-9487-0511"]},"institutions":[{"id":"https://openalex.org/I79619799","display_name":"University of Birmingham","ror":"https://ror.org/03angcq70","country_code":"GB","type":"education","lineage":["https://openalex.org/I79619799"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Adam Croft","raw_affiliation_strings":["University of Birmingham;"],"raw_orcid":"https://orcid.org/0000-0002-9487-0511","affiliations":[{"raw_affiliation_string":"University of Birmingham;","institution_ids":["https://openalex.org/I79619799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025153030","display_name":"Louis Boon","orcid":"https://orcid.org/0000-0002-0937-9171","observed_orcids":["https://orcid.org/0000-0002-0937-9171"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Louis Boon","raw_affiliation_strings":["JJP;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"JJP;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021185544","display_name":"Nicole Migotsky","orcid":"https://orcid.org/0000-0002-8478-4281","observed_orcids":["https://orcid.org/0000-0002-8478-4281"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Migotsky","raw_affiliation_strings":["University of Michigan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan;","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017760564","display_name":"Megan Leigh Killian","orcid":"https://orcid.org/0000-0001-6868-5550","observed_orcids":["https://orcid.org/0000-0001-6868-5550"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan L Killian","raw_affiliation_strings":["University of Michigan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Michigan;","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092066937","display_name":"Oumaima Ben Brahim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oumaima Ben Brahim","raw_affiliation_strings":["University of Erlangen;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Erlangen;","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040049345","display_name":"Stefan Uderhardt","orcid":"https://orcid.org/0000-0002-2489-2109","observed_orcids":["https://orcid.org/0000-0002-2489-2109"]},"institutions":[{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Uderhardt","raw_affiliation_strings":["Universitaetsklinikum Erlangen;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitaetsklinikum Erlangen;","institution_ids":["https://openalex.org/I4210088053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080179098","display_name":"Alexandre Gallerand","orcid":"https://orcid.org/0000-0002-3127-1343","observed_orcids":["https://orcid.org/0000-0002-3127-1343"]},"institutions":[{"id":"https://openalex.org/I201841394","display_name":"Universit\u00e9 C\u00f4te d'Azur","ror":"https://ror.org/019tgvf94","country_code":"FR","type":"education","lineage":["https://openalex.org/I201841394"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alexandre Gallerand","raw_affiliation_strings":["Universite Cote d Azur;"],"raw_orcid":"https://orcid.org/0000-0002-3127-1343","affiliations":[{"raw_affiliation_string":"Universite Cote d Azur;","institution_ids":["https://openalex.org/I201841394"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025235154","display_name":"Stoyan Ivanov","orcid":"https://orcid.org/0000-0002-0527-2297","observed_orcids":["https://orcid.org/0000-0002-0527-2297"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210091024","display_name":"Laboratoire de PhysioM\u00e9decine Mol\u00e9culaire","ror":"https://ror.org/00c3ktd57","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I201841394","https://openalex.org/I4210091024","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Stoyan Ivanov","raw_affiliation_strings":["Universite Cote d Azur, CNRS, LP2M"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universite Cote d Azur, CNRS, LP2M","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210091024"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160551642","display_name":"Rebecca Gentek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Rebecca Gentek","raw_affiliation_strings":["University of Edinburgh;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh;","institution_ids":["https://openalex.org/I98677209"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5160551642"],"corresponding_institution_ids":["https://openalex.org/I98677209"],"apc_list":{"value":5620,"currency":"USD","value_usd":5620},"apc_paid":{"value":5620,"currency":"USD","value_usd":5620},"fwci":7.6585,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.97625817,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"45","issue":"8","first_page":"117698","last_page":"117698"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.40230000019073486,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.40230000019073486,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.14390000700950623,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12800","display_name":"Musculoskeletal synovial abnormalities and treatments","score":0.05079999938607216,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postnatal-development","display_name":"postnatal development","score":0.8429999947547913},{"id":"https://openalex.org/keywords/monocyte-origin","display_name":"monocyte origin","score":0.5740000009536743},{"id":"https://openalex.org/keywords/tgf-beta-signaling","display_name":"TGF-beta signaling","score":0.8479999899864197},{"id":"https://openalex.org/keywords/joint-inflammation","display_name":"joint inflammation","score":0.6370000243186951},{"id":"https://openalex.org/keywords/joint-homeostasis","display_name":"joint homeostasis","score":0.6480000019073486}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5863000154495239},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5770999789237976},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.4140999913215637},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3352999985218048},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3109999895095825},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3102000057697296},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2928999960422516},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.2809999883174896},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27390000224113464},{"id":"https://openalex.org/C2777652487","wikidata":"https://www.wikidata.org/wiki/Q575064","display_name":"Synovial membrane","level":3,"score":0.2728999853134155},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2709999978542328},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.25609999895095825},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2549000084400177}],"mesh":[],"locations_count":8,"locations":[{"id":"doi:10.1016/j.celrep.2026.117698","doi":"https://doi.org/10.1016/j.celrep.2026.117698","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2026.117698","pdf_url":null,"source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},{"id":"doi:10.1101/2025.05.21.655269","doi":"https://doi.org/10.1101/2025.05.21.655269","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2025.05.21.655269","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2025/05/26/2025.05.21.655269.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:42603276","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42603276","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell reports","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire/4096a13e-81d4-4bc0-8cac-98368a2bb7e4","doi":null,"is_oa":true,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/4096a13e-81d4-4bc0-8cac-98368a2bb7e4","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:eprints.gla.ac.uk:393504","doi":null,"is_oa":true,"landing_page_url":"https://eprints.gla.ac.uk/view/journal_volume/Cell_Reports.html>,","pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/I4405259220","host_organization_name":"Institut Agama Islam Negeri Langsa","host_organization_lineage":["https://openalex.org/I4405259220"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Articles"},{"id":"pmh:oai:HAL:hal-05795429v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05795429","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Reports, 2026, 45 (8), pp.117698. ⟨10.1016/j.celrep.2026.117698⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/234298","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10356/234298","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/fabb0980-157c-4f6e-b918-30d0e6955af0","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/files/672675015/Magalhaes_Pinto_and_Malengier-Devlies_et_al._Elaine_Emmerson.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.celrep.2026.117698","doi":"https://doi.org/10.1016/j.celrep.2026.117698","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.celrep.2026.117698","pdf_url":null,"source":{"id":"https://openalex.org/S169236886","display_name":"Cell Reports","issn_l":"2211-1247","issn":["2211-1247","2639-1856"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1641517065","display_name":null,"funder_award_id":"22072","funder_id":"https://openalex.org/F4320327444","funder_display_name":"Versus Arthritis"},{"id":"https://openalex.org/G168679249","display_name":null,"funder_award_id":"RGS\\R2\\202277","funder_id":"https://openalex.org/F4320320006","funder_display_name":"Royal Society"},{"id":"https://openalex.org/G1784058465","display_name":"Investigating the role of TGF\u03b2 in the functional imprinting of pulmonary macrophages in health and disease","funder_award_id":"206234","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G2079317380","display_name":"Therapeutic role of CD44 in alcoholic liver diseases: from bone marrow myelopoiesis to liver inflammation","funder_award_id":"ANR-22-CE14-0027","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G2394575712","display_name":null,"funder_award_id":"101039438","funder_id":"https://openalex.org/F4320334678","funder_display_name":"European Research Council"},{"id":"https://openalex.org/G2605610293","display_name":null,"funder_award_id":"20205","funder_id":"https://openalex.org/F4320327444","funder_display_name":"Versus Arthritis"},{"id":"https://openalex.org/G2939858207","display_name":"Dissecting the cellular and molecular basis of macrophage-nerve crosstalk in the salivary gland in health and regeneration","funder_award_id":"MR/W004763/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G339059223","display_name":null,"funder_award_id":"Z/17/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G394222476","display_name":null,"funder_award_id":"KENN 19 20 07","funder_id":"https://openalex.org/F4320316694","funder_display_name":"Kennedy Trust for Rheumatology Research"},{"id":"https://openalex.org/G4142828022","display_name":"Metabolic control of IL-23 production in resident and migratory dendritic cells","funder_award_id":"ANR-21-CE15-0020","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G5728235598","display_name":null,"funder_award_id":"Z/17/Z","funder_id":"https://openalex.org/F4320320006","funder_display_name":"Royal Society"},{"id":"https://openalex.org/G5857119584","display_name":null,"funder_award_id":"21612","funder_id":"https://openalex.org/F4320327444","funder_display_name":"Versus Arthritis"},{"id":"https://openalex.org/G678342326","display_name":"Defining Brown Adipose Tissue Macrophage Diversity and Functions.","funder_award_id":"ANR-23-CE15-0032","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G6865351781","display_name":"Untersuchung gewebeprotektiver Funktionen von Makrophagen mittels integrativer und funktioneller Gewebebiologie.","funder_award_id":"448121430","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7080048889","display_name":null,"funder_award_id":"ANR-23","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G7080599860","display_name":"Network Synergies in Tissue Homeostasis and Stromal Prevention of Inflammatory Disease.","funder_award_id":"101039438","funder_id":"https://openalex.org/F4320338453","funder_display_name":"HORIZON EUROPE European Research Council"},{"id":"https://openalex.org/G7214974285","display_name":"Ether-Lipid Metabolism in Myeloid Cells in Atherosclerosis","funder_award_id":"ANR-23-CE14-0054","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G7333958791","display_name":null,"funder_award_id":"DRI-4005","funder_id":"https://openalex.org/F4320329730","funder_display_name":"UK Dementia Research Institute"},{"id":"https://openalex.org/G748436762","display_name":null,"funder_award_id":"UK DRI-4005","funder_id":"https://openalex.org/F4320329730","funder_display_name":"UK Dementia Research Institute"},{"id":"https://openalex.org/G7762209315","display_name":null,"funder_award_id":"206234/Z/17/Z","funder_id":"https://openalex.org/F4320320006","funder_display_name":"Royal Society"},{"id":"https://openalex.org/G8110842792","display_name":null,"funder_award_id":"23229","funder_id":"https://openalex.org/F4320327444","funder_display_name":"Versus Arthritis"},{"id":"https://openalex.org/G8146171561","display_name":"FOR 2886: PANDORA  Pathways triggering AutoimmuNity and Defining Onset of early Rheumatoid Arthritis","funder_award_id":"405969122","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8516145838","display_name":"TRR 369: DIONE Entz\u00fcndungsbedingte Knochendegeneration","funder_award_id":"501752319","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8931963569","display_name":"Investigating the role of TGF\u03b2 in the functional imprinting of pulmonary macrophages in health and disease","funder_award_id":"206234/Z/17/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320316694","display_name":"Kennedy Trust for Rheumatology Research","ror":"https://ror.org/03qhewz33"},{"id":"https://openalex.org/F4320320006","display_name":"Royal Society","ror":"https://ror.org/03wnrjx87"},{"id":"https://openalex.org/F4320320332","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320327444","display_name":"Versus Arthritis","ror":"https://ror.org/02jkpm469"},{"id":"https://openalex.org/F4320329730","display_name":"UK Dementia Research Institute","ror":"https://ror.org/02wedp412"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"},{"id":"https://openalex.org/F4320338453","display_name":"HORIZON EUROPE European Research Council","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203478805.pdf","grobid_xml":"https://content.openalex.org/works/W7203478805.grobid-xml"},"referenced_works_count":90,"referenced_works":["https://openalex.org/W1588400717","https://openalex.org/W1948478725","https://openalex.org/W1963904011","https://openalex.org/W1969559624","https://openalex.org/W1973433801","https://openalex.org/W1983227824","https://openalex.org/W2022084371","https://openalex.org/W2031603575","https://openalex.org/W2051282218","https://openalex.org/W2052504544","https://openalex.org/W2065639597","https://openalex.org/W2065784567","https://openalex.org/W2068714945","https://openalex.org/W2069264150","https://openalex.org/W2077946314","https://openalex.org/W2087101282","https://openalex.org/W2096147603","https://openalex.org/W2100646399","https://openalex.org/W2103764114","https://openalex.org/W2104989250","https://openalex.org/W2105074601","https://openalex.org/W2119616623","https://openalex.org/W2123797627","https://openalex.org/W2124841332","https://openalex.org/W2126811287","https://openalex.org/W2129422735","https://openalex.org/W2133351125","https://openalex.org/W2139249299","https://openalex.org/W2153406260","https://openalex.org/W2161057248","https://openalex.org/W2163774748","https://openalex.org/W2166791153","https://openalex.org/W2242760558","https://openalex.org/W2301038687","https://openalex.org/W2468094059","https://openalex.org/W2506892818","https://openalex.org/W2533905132","https://openalex.org/W2546492508","https://openalex.org/W2619923545","https://openalex.org/W2766437506","https://openalex.org/W2767487209","https://openalex.org/W2768278421","https://openalex.org/W2769477527","https://openalex.org/W2773534799","https://openalex.org/W2781660900","https://openalex.org/W2782793342","https://openalex.org/W2804230186","https://openalex.org/W2807207064","https://openalex.org/W2885821180","https://openalex.org/W2885879125","https://openalex.org/W2892433402","https://openalex.org/W2916020270","https://openalex.org/W2922341654","https://openalex.org/W2943911661","https://openalex.org/W2944564829","https://openalex.org/W2951799803","https://openalex.org/W2952638406","https://openalex.org/W2964143382","https://openalex.org/W2964834213","https://openalex.org/W2969551943","https://openalex.org/W2971790873","https://openalex.org/W2972939290","https://openalex.org/W2976606306","https://openalex.org/W2999745029","https://openalex.org/W3004574736","https://openalex.org/W3012091956","https://openalex.org/W3015181515","https://openalex.org/W3026851507","https://openalex.org/W3037615636","https://openalex.org/W3047141442","https://openalex.org/W3047224896","https://openalex.org/W3128616607","https://openalex.org/W3132940629","https://openalex.org/W3157700119","https://openalex.org/W3217761107","https://openalex.org/W4205428045","https://openalex.org/W4254025084","https://openalex.org/W4284972143","https://openalex.org/W4309621463","https://openalex.org/W4323924784","https://openalex.org/W4367311976","https://openalex.org/W4384560122","https://openalex.org/W4390099150","https://openalex.org/W4396889978","https://openalex.org/W4404677035","https://openalex.org/W4405050868","https://openalex.org/W4407954781","https://openalex.org/W4408007756","https://openalex.org/W4409907544","https://openalex.org/W4412849500"],"related_works":["https://openalex.org/W4410742553","https://openalex.org/W2095494709","https://openalex.org/W4309621463","https://openalex.org/W2964834213","https://openalex.org/W4410523705","https://openalex.org/W2950152938","https://openalex.org/W3036133538","https://openalex.org/W4389938404","https://openalex.org/W2100646399","https://openalex.org/W2046652474"],"abstract_inverted_index":{"Summary":[0],"Synovial":[1],"joints":[2],"harbor":[3],"a":[4,59,168],"protective":[5],"lining":[6,21,47,78,87,106,172],"layer,":[7],"consisting":[8],"of":[9,61,77,100],"fibroblasts":[10],"and":[11,29,50,64,71,92,118,134,145,182],"macrophages,":[12],"which":[13,51,153],"form":[14],"an":[15],"epithelial-like":[16],"barrier.":[17],"In":[18,102,124],"inflamed":[19],"joints,":[20],"macrophages":[22,111],"regulate":[23],"both":[24],"early":[25,164],"inflammatory":[26],"cell":[27,69],"influx":[28],"resolution.":[30],"Despite":[31],"these":[32],"critical":[33,169],"functions,":[34],"it":[35],"is":[36,48,88,107],"currently":[37],"unknown":[38],"at":[39,90],"what":[40],"stage":[41],"during":[42],"development":[43],"the":[44,75,85,96,105,120,131,163],"synovial":[45,86],"macrophage":[46,173],"established,":[49],"signals":[52,149],"drive":[53],"this":[54,103,151],"process.":[55],"Here,":[56],"we":[57],"use":[58],"combination":[60],"genetic":[62],"models":[63],"in":[65,80,139,150],"vivo":[66],"perturbations,":[67],"single":[68],"transcriptomics":[70],"imaging":[72],"to":[73,130],"delineate":[74],"process":[76],"formation":[79],"mice.":[81],"We":[82,142],"find":[83],"that":[84,112],"immature":[89],"birth":[91],"becomes":[93],"established":[94],"within":[95],"first":[97],"3":[98],"weeks":[99],"life.":[101],"window,":[104],"gradually":[108],"populated":[109],"with":[110,175],"originate":[113],"from":[114],"fetal":[115],"sources,":[116],"proliferate":[117],"acquire":[119],"lining-specific":[121],"transcriptional":[122],"identity.":[123],"contrast,":[125],"monocytes":[126],"contribute":[127],"only":[128],"minimally":[129],"developing":[132],"lining,":[133],"their":[135],"input":[136],"remains":[137],"limited":[138],"healthy":[140],"adulthood.":[141],"identify":[143],"CSF1":[144],"TGF\u03b2":[146],"as":[147,167],"key":[148],"process,":[152],"also":[154],"involves":[155],"mechanosensing":[156],"through":[157],"PIEZO1.":[158],"Our":[159],"study":[160],"thus":[161],"identifies":[162],"postnatal":[165],"window":[166],"period":[170],"for":[171],"development,":[174],"potential":[176],"lifelong":[177],"impact":[178],"on":[179],"joint":[180],"health":[181],"disease.":[183]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-15T00:00:00"}