{"id":"https://openalex.org/W7203474829","doi":"https://doi.org/10.1590/acb414826","title":"Application of melamine-starch and bixin film (Bixa orellana L.) in wound healing","display_name":"Application of melamine-starch and bixin film (Bixa orellana L.) in wound healing","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7203474829","doi":"https://doi.org/10.1590/acb414826","pmid":"https://pubmed.ncbi.nlm.nih.gov/42615766","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13475718"},"language":"en","primary_location":{"id":"doi:10.1590/acb414826","doi":"https://doi.org/10.1590/acb414826","is_oa":true,"landing_page_url":"https://doi.org/10.1590/acb414826","pdf_url":"https://www.scielo.br/j/acb/a/9XjjHWM97jjhPmMgH3GN33S/?lang=en&format=pdf","source":{"id":"https://openalex.org/S44202665","display_name":"Acta Cir\u00fargica Brasileira","issn_l":"0102-8650","issn":["0102-8650","1678-2674"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312195","host_organization_name":"Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia","host_organization_lineage":["https://openalex.org/P4310312195"],"host_organization_lineage_names":["Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cir\u00fargica Brasileira","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.scielo.br/j/acb/a/9XjjHWM97jjhPmMgH3GN33S/?lang=en&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101995447","display_name":"L\u00facia Rosa Reis de Ara\u00fajo Carvalho","orcid":"https://orcid.org/0000-0003-1475-6805","observed_orcids":["https://orcid.org/0000-0003-1475-6805"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"L\u00facia Rosa Reis de Ara\u00fajo Carvalho","raw_affiliation_strings":["Universidade Federal do Piau\u00ed,  Brazil","Universidade de S\u00e3o Paulo,  Brazil"],"raw_orcid":"https://orcid.org/0000-0003-1475-6805","affiliations":[{"raw_affiliation_string":"Universidade Federal do Piau\u00ed,  Brazil","institution_ids":["https://openalex.org/I3121799822"]},{"raw_affiliation_string":"Universidade de S\u00e3o Paulo,  Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063676949","display_name":"Maria do Amparo Veloso Magalh\u00e3es","orcid":"https://orcid.org/0000-0002-8330-3247","observed_orcids":["https://orcid.org/0000-0002-8330-3247"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria do Amparo Veloso Magalh\u00e3es","raw_affiliation_strings":["Centro de Tecnologia Educacional em Biotecnologia,  Brazil"],"raw_orcid":"https://orcid.org/0000-0002-8330-3247","affiliations":[{"raw_affiliation_string":"Centro de Tecnologia Educacional em Biotecnologia,  Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017864347","display_name":"Ant\u00f4nio Lu\u00edz Martins Maia Filho","orcid":"https://orcid.org/0000-0001-6184-8003","observed_orcids":["https://orcid.org/0000-0001-6184-8003"]},"institutions":[{"id":"https://openalex.org/I3123346794","display_name":"Universidade Estadual do Piau\u00ed","ror":"https://ror.org/02na6tz09","country_code":"BR","type":"education","lineage":["https://openalex.org/I3123346794"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ant\u00f4nio Luiz Martins Maia","raw_affiliation_strings":["Universidade Estadual do Piau\u00ed,  Brazil"],"raw_orcid":"https://orcid.org/0000-0001-6184-8003","affiliations":[{"raw_affiliation_string":"Universidade Estadual do Piau\u00ed,  Brazil","institution_ids":["https://openalex.org/I3123346794"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001090785","display_name":"Luciano Reis de Ara\u00fajo Carvalho","orcid":"https://orcid.org/0000-0002-8485-6222","observed_orcids":["https://orcid.org/0000-0002-8485-6222"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luciano Reis de Araujo Carvalho","raw_affiliation_strings":["Universidade Federal do Piau\u00ed,  Brazil","Universidade de S\u00e3o Paulo,  Brazil"],"raw_orcid":"https://orcid.org/0000-0002-8485-6222","affiliations":[{"raw_affiliation_string":"Universidade Federal do Piau\u00ed,  Brazil","institution_ids":["https://openalex.org/I3121799822"]},{"raw_affiliation_string":"Universidade de S\u00e3o Paulo,  Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009976457","display_name":"Isabella Mousinho Marinho dos Santos","orcid":"https://orcid.org/0000-0003-3911-717X","observed_orcids":["https://orcid.org/0000-0003-3911-717X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Isabella Mousinho Marinho dos Santos","raw_affiliation_strings":["Hospital S\u00e3o Marcos,  Brazil"],"raw_orcid":"https://orcid.org/0000-0003-3911-717X","affiliations":[{"raw_affiliation_string":"Hospital S\u00e3o Marcos,  Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086386874","display_name":"Lucielma Salmito Soares Pinto","orcid":"https://orcid.org/0000-0002-8766-8593","observed_orcids":["https://orcid.org/0000-0002-8766-8593"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lucielma Salmito Soares Pinto","raw_affiliation_strings":["Universidade Estadual de Campinas,  Brazil"],"raw_orcid":"https://orcid.org/0000-0002-8766-8593","affiliations":[{"raw_affiliation_string":"Universidade Estadual de Campinas,  Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047324403","display_name":"Jos\u00e9 Figueiredo Silva","orcid":"https://orcid.org/0000-0002-7117-8784","observed_orcids":["https://orcid.org/0000-0002-7117-8784"]},"institutions":[{"id":"https://openalex.org/I3123346794","display_name":"Universidade Estadual do Piau\u00ed","ror":"https://ror.org/02na6tz09","country_code":"BR","type":"education","lineage":["https://openalex.org/I3123346794"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Figueredo Silva","raw_affiliation_strings":["Universidade Estadual do Piau\u00ed,  Brazil"],"raw_orcid":"https://orcid.org/0000-0002-7117-8784","affiliations":[{"raw_affiliation_string":"Universidade Estadual do Piau\u00ed,  Brazil","institution_ids":["https://openalex.org/I3123346794"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033859589","display_name":"Jos\u00e9 Zilton Lima Verde Santos","orcid":"https://orcid.org/0000-0001-9877-1994","observed_orcids":["https://orcid.org/0000-0001-9877-1994"]},"institutions":[{"id":"https://openalex.org/I3123346794","display_name":"Universidade Estadual do Piau\u00ed","ror":"https://ror.org/02na6tz09","country_code":"BR","type":"education","lineage":["https://openalex.org/I3123346794"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jose Zilton Lima Verde Santos","raw_affiliation_strings":["Universidade Estadual do Piau\u00ed,  Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9877-1994","affiliations":[{"raw_affiliation_string":"Universidade Estadual do Piau\u00ed,  Brazil","institution_ids":["https://openalex.org/I3123346794"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002616565","display_name":"Jos\u00e9 Ribeiro dos Santos J\u00fanior","orcid":"https://orcid.org/0000-0003-2197-2020","observed_orcids":["https://orcid.org/0000-0003-2197-2020"]},"institutions":[{"id":"https://openalex.org/I3121799822","display_name":"Universidade Federal do Piau\u00ed","ror":"https://ror.org/00kwnx126","country_code":"BR","type":"education","lineage":["https://openalex.org/I3121799822"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Ribeiro dos Santos J\u00fanior","raw_affiliation_strings":["Universidade Federal do Piau\u00ed,  Brazil"],"raw_orcid":"https://orcid.org/0000-0003-2197-2020","affiliations":[{"raw_affiliation_string":"Universidade Federal do Piau\u00ed,  Brazil","institution_ids":["https://openalex.org/I3121799822"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5101995447"],"corresponding_institution_ids":["https://openalex.org/I17974374","https://openalex.org/I3121799822"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":null,"first_page":"e414826","last_page":"e414826"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12906","display_name":"Surgical Sutures and Adhesives","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.7919999957084656},{"id":"https://openalex.org/keywords/bixin","display_name":"bixin","score":0.75},{"id":"https://openalex.org/keywords/bixa-orellana","display_name":"Bixa orellana","score":0.9950000047683716},{"id":"https://openalex.org/keywords/skin-wounds","display_name":"skin wounds","score":0.7450000047683716},{"id":"https://openalex.org/keywords/re-epithelialization","display_name":"re-epithelialization","score":0.9470000267028809},{"id":"https://openalex.org/keywords/extracellular-matrix","display_name":"extracellular matrix","score":0.949999988079071},{"id":"https://openalex.org/keywords/collagen-deposition","display_name":"collagen deposition","score":0.9860000014305115},{"id":"https://openalex.org/keywords/fibroblast-proliferation","display_name":"fibroblast proliferation","score":0.9789999723434448},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7490000128746033},{"id":"https://openalex.org/keywords/topical-wound-dressing","display_name":"topical wound dressing","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.8568000197410583},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.6425999999046326},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.53329998254776},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4675000011920929},{"id":"https://openalex.org/C2776458125","wikidata":"https://www.wikidata.org/wiki/Q1827343","display_name":"Epidermis (zoology)","level":2,"score":0.4595000147819519},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.43230000138282776},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.421099990606308},{"id":"https://openalex.org/C3020610862","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue repair","level":2,"score":0.38440001010894775},{"id":"https://openalex.org/C190567982","wikidata":"https://www.wikidata.org/wiki/Q7535422","display_name":"Skin repair","level":3,"score":0.3610000014305115},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3434000015258789},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.33480000495910645},{"id":"https://openalex.org/C2994442579","wikidata":"https://www.wikidata.org/wiki/Q42395","display_name":"Inflammatory cell","level":3,"score":0.3296000063419342},{"id":"https://openalex.org/C2776055305","wikidata":"https://www.wikidata.org/wiki/Q1543255","display_name":"Granulation tissue","level":3,"score":0.3077000081539154},{"id":"https://openalex.org/C2778005187","wikidata":"https://www.wikidata.org/wiki/Q5262669","display_name":"Dermal fibroblast","level":4,"score":0.305400013923645},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.3019999861717224},{"id":"https://openalex.org/C2779797417","wikidata":"https://www.wikidata.org/wiki/Q12460151","display_name":"Hydroxyproline","level":2,"score":0.27320000529289246},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C2779703632","wikidata":"https://www.wikidata.org/wiki/Q581996","display_name":"Anti-inflammatory","level":2,"score":0.2551000118255615}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002338","descriptor_name":"Carotenoids","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002338","descriptor_name":"Carotenoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013213","descriptor_name":"Starch","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D013213","descriptor_name":"Starch","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014227","descriptor_name":"Triazines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D014227","descriptor_name":"Triazines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014227","descriptor_name":"Triazines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031212","descriptor_name":"Bixaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D062326","descriptor_name":"Re-Epithelialization","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1590/acb414826","doi":"https://doi.org/10.1590/acb414826","is_oa":true,"landing_page_url":"https://doi.org/10.1590/acb414826","pdf_url":"https://www.scielo.br/j/acb/a/9XjjHWM97jjhPmMgH3GN33S/?lang=en&format=pdf","source":{"id":"https://openalex.org/S44202665","display_name":"Acta Cir\u00fargica Brasileira","issn_l":"0102-8650","issn":["0102-8650","1678-2674"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312195","host_organization_name":"Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia","host_organization_lineage":["https://openalex.org/P4310312195"],"host_organization_lineage_names":["Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cir\u00fargica Brasileira","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13475718","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13475718/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13475718/pdf/1678-2674-acb-41-e414826.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cir Bras","raw_type":"Text"},{"id":"pmid:42615766","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42615766","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta cirurgica brasileira","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:ce1c8bab920e414f9a9d86fac8d774e0","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/ce1c8bab920e414f9a9d86fac8d774e0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta Cir\u00fargica Brasileira, Vol 41 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1590/acb414826","doi":"https://doi.org/10.1590/acb414826","is_oa":true,"landing_page_url":"https://doi.org/10.1590/acb414826","pdf_url":"https://www.scielo.br/j/acb/a/9XjjHWM97jjhPmMgH3GN33S/?lang=en&format=pdf","source":{"id":"https://openalex.org/S44202665","display_name":"Acta Cir\u00fargica Brasileira","issn_l":"0102-8650","issn":["0102-8650","1678-2674"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-40","russia-white-list-2","scielo"],"host_organization":"https://openalex.org/P4310312195","host_organization_name":"Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia","host_organization_lineage":["https://openalex.org/P4310312195"],"host_organization_lineage_names":["Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Cir\u00fargica Brasileira","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203474829.pdf","grobid_xml":"https://content.openalex.org/works/W7203474829.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1971500643","https://openalex.org/W2024818321","https://openalex.org/W2072718693","https://openalex.org/W2621934018","https://openalex.org/W3034813253","https://openalex.org/W3088570016","https://openalex.org/W3091175966","https://openalex.org/W3153146426","https://openalex.org/W3155228429","https://openalex.org/W3162568928","https://openalex.org/W3171352955","https://openalex.org/W4200381265","https://openalex.org/W4280500011","https://openalex.org/W4307817311","https://openalex.org/W4364355695","https://openalex.org/W4378418205","https://openalex.org/W4389680470","https://openalex.org/W4409727999"],"related_works":["https://openalex.org/W2001781383","https://openalex.org/W4409727999","https://openalex.org/W2283390884","https://openalex.org/W3156975960","https://openalex.org/W1927232351","https://openalex.org/W2426838864","https://openalex.org/W2293767453","https://openalex.org/W3175624630","https://openalex.org/W2315927297","https://openalex.org/W2914200518"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"evaluate":[2],"through":[3],"histological":[4,75,96],"analysis":[5,76],"the":[6,86,91,109,113,122,128,183],"application":[7],"of":[8,88],"starch-melamine":[9,170],"film":[10,63],"and":[11,55,74,82,101,112,141,162,181],"bixin":[12,174],"(Bixa":[13],"orellana":[14],"L.)":[15],"in":[16,19,136,145],"wound":[17,42,49,59,129],"healing":[18,67],"Wistar":[20,25],"rats.":[21],"METHODS:":[22],"Eighteen":[23],"male":[24],"rats":[26],"were":[27,143],"randomly":[28],"assigned":[29],"to":[30,177],"three":[31,89,92,147],"groups":[32,93],"(n":[33],"=":[34],"6":[35],"per":[36],"group):":[37],"Group":[38,46,56,149],"1":[39],"(control),":[40],"cutaneous":[41,48,58],"without":[43],"topical":[44],"treatment;":[45],"2,":[47],"treated":[50,60],"with":[51,61,98,155,173],"a":[52,62,156,163],"bixin-free":[53],"film;":[54],"3,":[57,80],"containing":[64],"bixin.":[65],"Wound":[66],"progression":[68],"was":[69,133],"monitored":[70],"by":[71],"photographic":[72],"documentation":[73],"on":[77],"postoperative":[78],"days":[79],"7,":[81],"14.":[83],"RESULTS:":[84],"At":[85],"end":[87],"days,":[90,108,121],"showed":[94],"similar":[95],"aspects":[97],"incipient":[99],"re-epithelialization":[100,132],"edematous":[102],"extracellular":[103],"matrix":[104],"(ECM).":[105],"After":[106,119],"seven":[107],"edema":[110],"decreased,":[111],"ECM":[114],"appeared":[115],"much":[116],"more":[117],"compact.":[118],"14":[120],"newly":[123],"formed":[124],"epidermis":[125],"extended":[126],"toward":[127],"center,":[130],"but":[131],"not":[134],"complete":[135],"any":[137],"group.":[138],"Fibroblast":[139],"proliferation":[140],"maturation":[142],"accentuated":[144],"all":[146],"groups.":[148],"3":[150],"(bixin":[151],"group)":[152],"exhibited":[153],"wounds":[154],"dense":[157],"matrix,":[158],"increased":[159],"collagen":[160],"deposition,":[161],"minimal":[164],"inflammatory":[165,184],"cell":[166],"infiltrate.":[167],"CONCLUSION:":[168],"The":[169],"composite":[171],"associated":[172],"demonstrated":[175],"potential":[176],"enhance":[178],"tissue":[179],"repair":[180],"modulate":[182],"response.":[185]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-08-15T00:00:00"}