{"id":"https://openalex.org/W7203472453","doi":"https://doi.org/10.3389/fcell.2026.1841670","title":"Mechanical constraints on cell plasticity: insights from the olfactory epithelium","display_name":"Mechanical constraints on cell plasticity: insights from the olfactory epithelium","publication_year":2026,"publication_date":"2026-08-14","ids":{"openalex":"https://openalex.org/W7203472453","doi":"https://doi.org/10.3389/fcell.2026.1841670","pmid":"https://pubmed.ncbi.nlm.nih.gov/42666419","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13522167"},"language":"en","primary_location":{"id":"doi:10.3389/fcell.2026.1841670","doi":"https://doi.org/10.3389/fcell.2026.1841670","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcell.2026.1841670","pdf_url":"https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2026.1841670/pdf","source":{"id":"https://openalex.org/S2596924766","display_name":"Frontiers in Cell and Developmental Biology","issn_l":"2296-634X","issn":["2296-634X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cell and Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2026.1841670/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107299635","display_name":"Rapha\u00ebl Aguillon","orcid":"https://orcid.org/0000-0002-1149-0362","observed_orcids":["https://orcid.org/0000-0002-1149-0362","https://orcid.org/0000-0001-7362-8446"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210086591","display_name":"Photobiologie et Physiologie des Plastes et Microalgues","ror":"https://ror.org/001r32c80","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210086591","https://openalex.org/I4210096427"]},{"id":"https://openalex.org/I4210107423","display_name":"Institut de Biologie Physico-Chimique","ror":"https://ror.org/01na0pb61","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210107423"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Rapha\u00ebl Aguillon","raw_affiliation_strings":["Laboratoire de Photobiologie et Physiologie des Plastes et des Microalgues, CNRS, Sorbonne Universit\u00e9, Institut de Biologie Physico-Chimique"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Photobiologie et Physiologie des Plastes et des Microalgues, CNRS, Sorbonne Universit\u00e9, Institut de Biologie Physico-Chimique","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210086591","https://openalex.org/I4210107423"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pascale Dufourcq","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4405258862","display_name":"Universit\u00e9 de Toulouse","ror":"https://ror.org/01ahyrz84","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4405266242","display_name":"Centre de Biologie Int\u00e9grative de Toulouse","ror":"https://ror.org/01f4pb571","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4405258862","https://openalex.org/I4405266242"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pascale Dufourcq","raw_affiliation_strings":["University of Toulouse, CNRS, Centre de Biologie Integrative CBI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Toulouse, CNRS, Centre de Biologie Integrative CBI","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4405258862","https://openalex.org/I4405266242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045141908","display_name":"Julie Batut","orcid":"https://orcid.org/0000-0002-1984-2094","observed_orcids":["https://orcid.org/0000-0002-1984-2094"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4405258862","display_name":"Universit\u00e9 de Toulouse","ror":"https://ror.org/01ahyrz84","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4405266242","display_name":"Centre de Biologie Int\u00e9grative de Toulouse","ror":"https://ror.org/01f4pb571","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4405258862","https://openalex.org/I4405266242"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Julie Batut","raw_affiliation_strings":["University of Toulouse, CNRS, Centre de Biologie Integrative CBI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Toulouse, CNRS, Centre de Biologie Integrative CBI","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4405258862","https://openalex.org/I4405266242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5045141908"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4405258862","https://openalex.org/I4405266242"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.32524272,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":"1841670","last_page":"1841670"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.6615999937057495,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.2125999927520752,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.07919999957084656,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/olfactory-epithelium","display_name":"olfactory epithelium","score":0.9990000128746033},{"id":"https://openalex.org/keywords/stem-cell-plasticity","display_name":"stem cell plasticity","score":0.8169999718666077},{"id":"https://openalex.org/keywords/mechanobiology","display_name":"mechanobiology","score":0.9610000252723694},{"id":"https://openalex.org/keywords/tissue-stiffness","display_name":"tissue stiffness","score":0.6179999709129333},{"id":"https://openalex.org/keywords/basal-cells","display_name":"basal cells","score":0.8080000281333923},{"id":"https://openalex.org/keywords/horizontal-basal-cells","display_name":"horizontal basal cells","score":0.6859999895095825},{"id":"https://openalex.org/keywords/globose-basal-cells","display_name":"globose basal cells","score":0.9860000014305115},{"id":"https://openalex.org/keywords/olfactory-neurogenesis","display_name":"olfactory neurogenesis","score":0.7179999947547913},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.5080000162124634},{"id":"https://openalex.org/keywords/pseudostratified-columnar-epithelium","display_name":"pseudostratified epithelium","score":0.9470000267028809},{"id":"https://openalex.org/keywords/yap","display_name":"YAP","score":0.7609999775886536},{"id":"https://openalex.org/keywords/cxcr4","display_name":"CXCR4","score":0.9990000128746033},{"id":"https://openalex.org/keywords/retinoic-acid","display_name":"retinoic acid","score":0.996999979019165},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.8460000157356262},{"id":"https://openalex.org/keywords/kallmann-syndrome","display_name":"Kallmann syndrome","score":0.9829999804496765},{"id":"https://openalex.org/keywords/mechanoregulation","display_name":"mechanoregulation","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.682200014591217},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6590999960899353},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.603600025177002},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6028000116348267},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6001999974250793},{"id":"https://openalex.org/C2780171871","wikidata":"https://www.wikidata.org/wiki/Q6804676","display_name":"Mechanobiology","level":2,"score":0.545799970626831},{"id":"https://openalex.org/C2780187430","wikidata":"https://www.wikidata.org/wiki/Q3052544","display_name":"Olfactory epithelium","level":3,"score":0.5187000036239624},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5174000263214111},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5029000043869019},{"id":"https://openalex.org/C15729860","wikidata":"https://www.wikidata.org/wiki/Q2329919","display_name":"Progenitor","level":4,"score":0.445499986410141},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.40369999408721924},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.3961000144481659},{"id":"https://openalex.org/C153991713","wikidata":"https://www.wikidata.org/wiki/Q17142856","display_name":"Niche","level":2,"score":0.3675000071525574},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.36480000615119934},{"id":"https://openalex.org/C201792869","wikidata":"https://www.wikidata.org/wiki/Q1054094","display_name":"Olfactory system","level":2,"score":0.35929998755455017},{"id":"https://openalex.org/C2780205056","wikidata":"https://www.wikidata.org/wiki/Q7308048","display_name":"Regenerative process","level":3,"score":0.35409998893737793},{"id":"https://openalex.org/C2781377823","wikidata":"https://www.wikidata.org/wiki/Q7086517","display_name":"Olfactory mucosa","level":3,"score":0.34150001406669617},{"id":"https://openalex.org/C163952510","wikidata":"https://www.wikidata.org/wiki/Q5058196","display_name":"Cell fate determination","level":4,"score":0.3343999981880188},{"id":"https://openalex.org/C164794517","wikidata":"https://www.wikidata.org/wiki/Q16729831","display_name":"Stem cell niche","level":4,"score":0.33169999718666077},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.3149000108242035},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3070000112056732},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.30379998683929443},{"id":"https://openalex.org/C79186407","wikidata":"https://www.wikidata.org/wiki/Q472074","display_name":"Plasticity","level":2,"score":0.299699991941452},{"id":"https://openalex.org/C20875687","wikidata":"https://www.wikidata.org/wiki/Q2642600","display_name":"Adult stem cell","level":4,"score":0.29919999837875366},{"id":"https://openalex.org/C2776637008","wikidata":"https://www.wikidata.org/wiki/Q14860072","display_name":"Sonic hedgehog","level":3,"score":0.2906000018119812},{"id":"https://openalex.org/C183074962","wikidata":"https://www.wikidata.org/wiki/Q213713","display_name":"Developmental biology","level":2,"score":0.28790000081062317},{"id":"https://openalex.org/C35496256","wikidata":"https://www.wikidata.org/wiki/Q5104524","display_name":"Chondrogenesis","level":3,"score":0.2768000066280365},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.27410000562667847},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.2736999988555908},{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.27230000495910645},{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.2702000141143799},{"id":"https://openalex.org/C2776458125","wikidata":"https://www.wikidata.org/wiki/Q1827343","display_name":"Epidermis (zoology)","level":2,"score":0.2700999975204468},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.26899999380111694},{"id":"https://openalex.org/C137738243","wikidata":"https://www.wikidata.org/wiki/Q189092","display_name":"Cell migration","level":3,"score":0.2614000141620636}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fcell.2026.1841670","doi":"https://doi.org/10.3389/fcell.2026.1841670","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcell.2026.1841670","pdf_url":"https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2026.1841670/pdf","source":{"id":"https://openalex.org/S2596924766","display_name":"Frontiers in Cell and Developmental Biology","issn_l":"2296-634X","issn":["2296-634X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cell and Developmental Biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13522167","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13522167/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13522167/pdf/fcell-14-1841670.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cell Dev Biol","raw_type":"Text"},{"id":"pmid:42666419","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42666419","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cell and developmental biology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05777324v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05777324","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cell and Developmental Biology, 2026, 14, &#x27E8;10.3389/fcell.2026.1841670&#x27E9;","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:aa0a9540f07b4ce6b363fa466805530c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/aa0a9540f07b4ce6b363fa466805530c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cell and Developmental Biology, Vol 14 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fcell.2026.1841670","doi":"https://doi.org/10.3389/fcell.2026.1841670","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcell.2026.1841670","pdf_url":"https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2026.1841670/pdf","source":{"id":"https://openalex.org/S2596924766","display_name":"Frontiers in Cell and Developmental Biology","issn_l":"2296-634X","issn":["2296-634X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cell and Developmental Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5080192285","display_name":"Zebrafish Olfactory Organ Research: building blocks for Reconstructing its Origin","funder_award_id":"ANR-23-CE45-0021","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G7080048889","display_name":null,"funder_award_id":"ANR-23","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7203472453.pdf","grobid_xml":"https://content.openalex.org/works/W7203472453.grobid-xml"},"referenced_works_count":117,"referenced_works":["https://openalex.org/W1519287420","https://openalex.org/W1560976558","https://openalex.org/W1592493097","https://openalex.org/W1968597070","https://openalex.org/W1969312924","https://openalex.org/W1975781078","https://openalex.org/W1979069664","https://openalex.org/W1984480267","https://openalex.org/W1988816781","https://openalex.org/W1992292950","https://openalex.org/W1994954453","https://openalex.org/W1996963467","https://openalex.org/W1997358811","https://openalex.org/W2002113523","https://openalex.org/W2009908021","https://openalex.org/W2014384102","https://openalex.org/W2015340677","https://openalex.org/W2021014465","https://openalex.org/W2026652581","https://openalex.org/W2043918544","https://openalex.org/W2047334208","https://openalex.org/W2048847916","https://openalex.org/W2057347583","https://openalex.org/W2065724536","https://openalex.org/W2068543470","https://openalex.org/W2072070420","https://openalex.org/W2081128785","https://openalex.org/W2082573541","https://openalex.org/W2092352136","https://openalex.org/W2097679878","https://openalex.org/W2103180978","https://openalex.org/W2122087314","https://openalex.org/W2125862744","https://openalex.org/W2134208433","https://openalex.org/W2147292469","https://openalex.org/W2151792462","https://openalex.org/W2156859975","https://openalex.org/W2172159477","https://openalex.org/W2182268835","https://openalex.org/W2296735293","https://openalex.org/W2307414971","https://openalex.org/W2418338024","https://openalex.org/W2465767680","https://openalex.org/W2482879788","https://openalex.org/W2512311410","https://openalex.org/W2560819934","https://openalex.org/W2613078538","https://openalex.org/W2692764270","https://openalex.org/W2734413776","https://openalex.org/W2742334864","https://openalex.org/W2767734597","https://openalex.org/W2768413599","https://openalex.org/W2769220533","https://openalex.org/W2769547463","https://openalex.org/W2781555778","https://openalex.org/W2782770270","https://openalex.org/W2782855338","https://openalex.org/W2792424235","https://openalex.org/W2801674050","https://openalex.org/W2804583160","https://openalex.org/W2808153635","https://openalex.org/W2809032341","https://openalex.org/W2888670687","https://openalex.org/W2949219767","https://openalex.org/W2974514979","https://openalex.org/W2979665306","https://openalex.org/W2992194970","https://openalex.org/W2996254519","https://openalex.org/W3012397626","https://openalex.org/W3022894063","https://openalex.org/W3022992884","https://openalex.org/W3082435779","https://openalex.org/W3097042492","https://openalex.org/W3103132446","https://openalex.org/W3113697064","https://openalex.org/W3120204066","https://openalex.org/W3124766917","https://openalex.org/W3185731648","https://openalex.org/W3203078429","https://openalex.org/W3203743280","https://openalex.org/W4210988518","https://openalex.org/W4211057724","https://openalex.org/W4220666354","https://openalex.org/W4220676233","https://openalex.org/W4221103146","https://openalex.org/W4226062205","https://openalex.org/W4226094956","https://openalex.org/W4226244308","https://openalex.org/W4307037630","https://openalex.org/W4308370241","https://openalex.org/W4308963721","https://openalex.org/W4311189604","https://openalex.org/W4318962948","https://openalex.org/W4321793243","https://openalex.org/W4364376328","https://openalex.org/W4378953393","https://openalex.org/W4382810432","https://openalex.org/W4385476319","https://openalex.org/W4386245416","https://openalex.org/W4387579488","https://openalex.org/W4388217741","https://openalex.org/W4389728702","https://openalex.org/W4391428433","https://openalex.org/W4392919064","https://openalex.org/W4400410749","https://openalex.org/W4403395862","https://openalex.org/W4404809214","https://openalex.org/W4406253089","https://openalex.org/W4411282873","https://openalex.org/W4412002762","https://openalex.org/W4412707845","https://openalex.org/W4412856329","https://openalex.org/W4413323996","https://openalex.org/W4414805108","https://openalex.org/W4415049649","https://openalex.org/W4416715218","https://openalex.org/W7117464249"],"related_works":["https://openalex.org/W7163172817","https://openalex.org/W4388284345","https://openalex.org/W2091708438","https://openalex.org/W2767569544","https://openalex.org/W4391359097","https://openalex.org/W2966753303","https://openalex.org/W2094818243","https://openalex.org/W3080150445","https://openalex.org/W2043822782","https://openalex.org/W7119124570"],"abstract_inverted_index":{"The":[0],"olfactory":[1,111],"epithelium":[2],"(OE)":[3],"is":[4,39,158],"a":[5],"unique":[6,84],"model":[7],"to":[8,66,80,128],"study":[9],"how":[10,106],"mechanical":[11],"forces":[12,153],"and":[13,25,33,44,53,78,93,122,126,136,148,154],"tissue":[14,149],"architecture":[15,43],"regulate":[16],"stem":[17,134],"cell":[18,135],"plasticity.":[19,138],"In":[20],"vertebrate,":[21],"its":[22],"lifelong":[23],"neurogenesis":[24],"regenerative":[26],"capacity":[27],"depend":[28],"on":[29],"horizontal":[30],"basal":[31,35,63],"cells":[32],"globose":[34],"cells,":[36],"whose":[37],"plasticity":[38,101],"gated":[40],"by":[41],"niche":[42,64],"morphogenetic":[45],"cues.":[46],"While":[47],"molecular":[48],"pathways":[49,95],"in":[50,113],"OE":[51,88],"development":[52],"regeneration":[54],"are":[55],"well-characterized,":[56],"the":[57,83,87,130,142,146],"role":[58],"of":[59,86],"physical":[60],"forces,":[61],"from":[62],"stiffness":[65],"lamellar":[67],"folding,":[68],"remains":[69],"unexplored.":[70],"This":[71],"review":[72],"integrates":[73],"single-cell":[74],"analyses,":[75],"developmental":[76],"studies,":[77],"mechanobiology":[79],"propose":[81],"that":[82],"structure":[85],"(pseudostratified":[89],"epithelium,":[90],"spatial":[91],"compartmentalization)":[92],"conserved":[94],"(YAP,":[96],"CXCR4,":[97],"retinoic":[98],"acid)":[99],"coordinate":[100],"across":[102],"ontogeny.":[103],"We":[104],"discuss":[105],"disrupted":[107],"mechanoregulation":[108],"might":[109],"drive":[110],"deficits":[112],"aging,":[114],"infection":[115],"(COVID-19),":[116],"congenital":[117],"disorders":[118],"(Kallmann":[119],"syndrome),":[120],"cancer,":[121],"outline":[123],"key":[124],"questions":[125],"processes":[127],"decode":[129],"mechanobiological":[131],"rules":[132],"governing":[133],"progenitor":[137],"A":[139],"table":[140],"summarising":[141],"tools":[143],"available":[144],"at":[145],"cellular":[147],"levels":[150],"for":[151],"manipulating":[152],"visualising":[155],"their":[156],"effects":[157],"provided.":[159]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-08-15T00:00:00"}
