{"id":"https://openalex.org/W7202366554","doi":"https://doi.org/10.1016/j.biomaterials.2026.124549","title":"Magnetic hydrogel encapsulation combined with on-chip processing enhances straw vitrification of mouse oocytes","display_name":"Magnetic hydrogel encapsulation combined with on-chip processing enhances straw vitrification of mouse oocytes","publication_year":2026,"publication_date":"2026-08-13","ids":{"openalex":"https://openalex.org/W7202366554","doi":"https://doi.org/10.1016/j.biomaterials.2026.124549","pmid":"https://pubmed.ncbi.nlm.nih.gov/42604619"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomaterials.2026.124549","doi":"https://doi.org/10.1016/j.biomaterials.2026.124549","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2026.124549","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5147095097","display_name":"Yu Lei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Lei","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147062494","display_name":"Zhixiang Fang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhixiang Fang","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147129595","display_name":"Mulin Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mulin Wei","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147085448","display_name":"Chengyang Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chengyang Guo","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056610661","display_name":"Yue Cheng","orcid":"https://orcid.org/0000-0003-3640-4616","observed_orcids":["https://orcid.org/0000-0003-3640-4616"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yue Cheng","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China. Electronic address: chengy@ahmu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China. Electronic address: chengy@ahmu.edu.cn","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068723200","display_name":"Gang Zhao","orcid":"https://orcid.org/0000-0002-0201-1825","observed_orcids":["https://orcid.org/0000-0002-0201-1825"]},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Gang Zhao","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China; Department of Electronic Engineering and Information Science, University of Science and Technology of China, Hefei, China; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, China. Electronic address: zhaog@ustc.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-0201-1825","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China; Department of Electronic Engineering and Information Science, University of Science and Technology of China, Hefei, China; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, China. Electronic address: zhaog@ustc.edu.cn","institution_ids":["https://openalex.org/I126520041","https://openalex.org/I197869895"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013291471","display_name":"Zhongrong Chen","orcid":"https://orcid.org/0000-0002-4007-4800","observed_orcids":["https://orcid.org/0000-0002-4007-4800","https://orcid.org/0000-0002-0141-9036"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhongrong Chen","raw_affiliation_strings":["School of Biomedical Engineering, Anhui Medical University, Hefei, China; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, China. Electronic address: zhrchen@ahmu.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-4007-4800","affiliations":[{"raw_affiliation_string":"School of Biomedical Engineering, Anhui Medical University, Hefei, China; Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, China. Electronic address: zhrchen@ahmu.edu.cn","institution_ids":["https://openalex.org/I197869895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5013291471","https://openalex.org/A5056610661","https://openalex.org/A5068723200"],"corresponding_institution_ids":["https://openalex.org/I126520041","https://openalex.org/I197869895"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.60671234,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"337","issue":null,"first_page":"124549","last_page":"124549"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oocyte-cryopreservation","display_name":"oocyte cryopreservation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/microfluidics","display_name":"microfluidics","score":0.9539999961853027},{"id":"https://openalex.org/keywords/osmotic-shock","display_name":"osmotic shock","score":0.7919999957084656},{"id":"https://openalex.org/keywords/oocyte-survival","display_name":"oocyte survival","score":0.7099999785423279},{"id":"https://openalex.org/keywords/mitochondrial-activity","display_name":"mitochondrial activity","score":0.9300000071525574},{"id":"https://openalex.org/keywords/mouse-oocytes","display_name":"mouse oocytes","score":0.7379999756813049}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.708299994468689},{"id":"https://openalex.org/C2778022349","wikidata":"https://www.wikidata.org/wiki/Q1072553","display_name":"Vitrification","level":2,"score":0.6442000269889832},{"id":"https://openalex.org/C2776690073","wikidata":"https://www.wikidata.org/wiki/Q3246226","display_name":"Oocyte","level":3,"score":0.6384999752044678},{"id":"https://openalex.org/C179933525","wikidata":"https://www.wikidata.org/wiki/Q1144664","display_name":"Cryopreservation","level":3,"score":0.6154999732971191},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5139999985694885},{"id":"https://openalex.org/C63662833","wikidata":"https://www.wikidata.org/wiki/Q6839341","display_name":"Microchannel","level":2,"score":0.4235000014305115},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.41769999265670776},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4120999872684479},{"id":"https://openalex.org/C2988198817","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Microfluidic chip","level":3,"score":0.31630000472068787},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3043000102043152},{"id":"https://openalex.org/C2778459216","wikidata":"https://www.wikidata.org/wiki/Q3561328","display_name":"Oocyte cryopreservation","level":5,"score":0.30309998989105225},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.3003000020980835},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.2937999963760376},{"id":"https://openalex.org/C194051981","wikidata":"https://www.wikidata.org/wiki/Q1337691","display_name":"Economic shortage","level":3,"score":0.29319998621940613},{"id":"https://openalex.org/C2775966511","wikidata":"https://www.wikidata.org/wiki/Q2275655","display_name":"In vitro maturation","level":4,"score":0.28189998865127563},{"id":"https://openalex.org/C68528507","wikidata":"https://www.wikidata.org/wiki/Q692267","display_name":"Cryoprotectant","level":4,"score":0.2669999897480011},{"id":"https://openalex.org/C68760520","wikidata":"https://www.wikidata.org/wiki/Q882097","display_name":"Blastomere","level":4,"score":0.26660001277923584},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.258899986743927}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003451","descriptor_name":"Cryoprotective Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008280","descriptor_name":"Magnetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D015925","descriptor_name":"Cryopreservation","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D015925","descriptor_name":"Cryopreservation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D020136","descriptor_name":"Hydrogel, Polyethylene Glycol Dimethacrylate","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056656","descriptor_name":"Lab-On-A-Chip Devices","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058989","descriptor_name":"Vitrification","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biomaterials.2026.124549","doi":"https://doi.org/10.1016/j.biomaterials.2026.124549","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2026.124549","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"pmid:42604619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42604619","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3914619050","display_name":null,"funder_award_id":"52206064","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4364161232","display_name":null,"funder_award_id":"YQZD2025021","funder_id":"https://openalex.org/F4320326664","funder_display_name":"Anhui Provincial Department of Education"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326664","display_name":"Anhui Provincial Department of Education","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1942046563","https://openalex.org/W2023895282","https://openalex.org/W2082254966","https://openalex.org/W2098195656","https://openalex.org/W2107321242","https://openalex.org/W2160865238","https://openalex.org/W2171779389","https://openalex.org/W2327275730","https://openalex.org/W2522022397","https://openalex.org/W2580773030","https://openalex.org/W2581698010","https://openalex.org/W2591278399","https://openalex.org/W2598275663","https://openalex.org/W2765963789","https://openalex.org/W2801403250","https://openalex.org/W2802070058","https://openalex.org/W2906673606","https://openalex.org/W2937329190","https://openalex.org/W2977546035","https://openalex.org/W3010557055","https://openalex.org/W3013192738","https://openalex.org/W3044869207","https://openalex.org/W3127488895","https://openalex.org/W3160346726","https://openalex.org/W3172822442","https://openalex.org/W3177482428","https://openalex.org/W3194324507","https://openalex.org/W3213793954","https://openalex.org/W4200005740","https://openalex.org/W4223444347","https://openalex.org/W4242539340","https://openalex.org/W4282596311","https://openalex.org/W4285730790","https://openalex.org/W4311738435","https://openalex.org/W4312112356","https://openalex.org/W4321598379","https://openalex.org/W4389767151","https://openalex.org/W4391034626","https://openalex.org/W4392794088","https://openalex.org/W4393981596","https://openalex.org/W4394777482","https://openalex.org/W4402233498","https://openalex.org/W4402499174","https://openalex.org/W4403059472","https://openalex.org/W4404920421","https://openalex.org/W4408022496","https://openalex.org/W4408675786","https://openalex.org/W4408916561","https://openalex.org/W4410495264","https://openalex.org/W4411136806","https://openalex.org/W4411926984"],"related_works":["https://openalex.org/W4414382186","https://openalex.org/W3183818975","https://openalex.org/W4408675786","https://openalex.org/W4296525643","https://openalex.org/W7030313751","https://openalex.org/W2969712227","https://openalex.org/W4402825011","https://openalex.org/W2903402785","https://openalex.org/W4399732786","https://openalex.org/W4251328156"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2026-08-14T00:00:00"}