{"id":"https://openalex.org/W7202275175","doi":"https://doi.org/10.1177/1098612x261478796","title":"Prevalence and clinical relevance of hypocobalaminaemia and hypercobalaminaemia in cats","display_name":"Prevalence and clinical relevance of hypocobalaminaemia and hypercobalaminaemia in cats","publication_year":2026,"publication_date":"2026-08-11","ids":{"openalex":"https://openalex.org/W7202275175","doi":"https://doi.org/10.1177/1098612x261478796","pmid":"https://pubmed.ncbi.nlm.nih.gov/42581418"},"language":"en","primary_location":{"id":"doi:10.1177/1098612x261478796","doi":"https://doi.org/10.1177/1098612x261478796","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1098612x261478796","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1098612X261478796?download=true","source":{"id":"https://openalex.org/S7204592","display_name":"Journal of Feline Medicine and Surgery","issn_l":"1098-612X","issn":["1098-612X","1532-2750"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Feline Medicine and Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/1098612X261478796?download=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056891866","display_name":"Clara Mayo de las Casas","orcid":"https://orcid.org/0009-0007-4265-8248","observed_orcids":["https://orcid.org/0009-0007-4265-8248"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Clara Casas","raw_affiliation_strings":["Dovecote Veterinary Referrals, Castle Donington, Derby, UK","Pride Veterinary Referrals, Derby, UK"],"raw_orcid":"https://orcid.org/0009-0007-4265-8248","affiliations":[{"raw_affiliation_string":"Dovecote Veterinary Referrals, Castle Donington, Derby, UK","institution_ids":[]},{"raw_affiliation_string":"Pride Veterinary Referrals, Derby, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072938100","display_name":"Charlotte Dye","orcid":"https://orcid.org/0000-0001-7270-120X","observed_orcids":["https://orcid.org/0000-0001-7270-120X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charlotte Dye","raw_affiliation_strings":["Pride Veterinary Referrals, Derby, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pride Veterinary Referrals, Derby, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5056891866"],"corresponding_institution_ids":[],"apc_list":{"value":1800,"currency":"USD","value_usd":1800},"apc_paid":{"value":1800,"currency":"USD","value_usd":1800},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"11","first_page":"1098612X261478796","last_page":"1098612X261478796"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.6963000297546387,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.6963000297546387,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.2833999991416931,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-b12","display_name":"vitamin B12","score":0.8960000276565552},{"id":"https://openalex.org/keywords/cats","display_name":"cats","score":0.7760000228881836},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.7599999904632568},{"id":"https://openalex.org/keywords/age-related-decline","display_name":"age-related decline","score":0.5960000157356262},{"id":"https://openalex.org/keywords/body-weight","display_name":"body weight","score":0.9890000224113464},{"id":"https://openalex.org/keywords/body-condition-score","display_name":"body condition score","score":0.7350000143051147},{"id":"https://openalex.org/keywords/signalment","display_name":"signalment","score":0.5740000009536743},{"id":"https://openalex.org/keywords/disease-pathology","display_name":"disease pathology","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C2779904517","wikidata":"https://www.wikidata.org/wiki/Q5008900","display_name":"CATS","level":2,"score":0.897599995136261},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8640000224113464},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.6658999919891357},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5694000124931335},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48019999265670776},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4666999876499176},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.45680001378059387},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.41909998655319214},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.41370001435279846},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.37630000710487366},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.33899998664855957},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.3377000093460083},{"id":"https://openalex.org/C2776135927","wikidata":"https://www.wikidata.org/wiki/Q5242559","display_name":"Referral","level":2,"score":0.32499998807907104},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3066999912261963},{"id":"https://openalex.org/C529978579","wikidata":"https://www.wikidata.org/wiki/Q499500","display_name":"Clinical pathology","level":2,"score":0.3057999908924103},{"id":"https://openalex.org/C2776376844","wikidata":"https://www.wikidata.org/wiki/Q886518","display_name":"Complete blood count","level":2,"score":0.28130000829696655},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.2766000032424927},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.27559998631477356},{"id":"https://openalex.org/C2778143274","wikidata":"https://www.wikidata.org/wiki/Q1626599","display_name":"Reference range","level":2,"score":0.2689000070095062},{"id":"https://openalex.org/C2992264114","wikidata":"https://www.wikidata.org/wiki/Q1394551","display_name":"Clinical disease","level":3,"score":0.2547999918460846},{"id":"https://openalex.org/C527108885","wikidata":"https://www.wikidata.org/wiki/Q835153","display_name":"Physical examination","level":2,"score":0.25189998745918274},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.2500999867916107}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002371","descriptor_name":"Cat Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002371","descriptor_name":"Cat Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014805","descriptor_name":"Vitamin B 12","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014806","descriptor_name":"Vitamin B 12 Deficiency","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014806","descriptor_name":"Vitamin B 12 Deficiency","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D014806","descriptor_name":"Vitamin B 12 Deficiency","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1177/1098612x261478796","doi":"https://doi.org/10.1177/1098612x261478796","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1098612x261478796","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1098612X261478796?download=true","source":{"id":"https://openalex.org/S7204592","display_name":"Journal of Feline Medicine and Surgery","issn_l":"1098-612X","issn":["1098-612X","1532-2750"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Feline Medicine and Surgery","raw_type":"journal-article"},{"id":"pmid:42581418","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42581418","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of feline medicine and surgery","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:5fa6b309fcc64c5490942c748b28b74c","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/5fa6b309fcc64c5490942c748b28b74c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Feline Medicine and Surgery, Vol 28 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/1098612x261478796","doi":"https://doi.org/10.1177/1098612x261478796","is_oa":true,"landing_page_url":"https://doi.org/10.1177/1098612x261478796","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/1098612X261478796?download=true","source":{"id":"https://openalex.org/S7204592","display_name":"Journal of Feline Medicine and Surgery","issn_l":"1098-612X","issn":["1098-612X","1532-2750"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","jufo-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Feline Medicine and Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7202275175.pdf","grobid_xml":"https://content.openalex.org/works/W7202275175.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W201027736","https://openalex.org/W975418452","https://openalex.org/W1534651612","https://openalex.org/W1648713263","https://openalex.org/W1998624519","https://openalex.org/W2025620465","https://openalex.org/W2027849963","https://openalex.org/W2034928770","https://openalex.org/W2035056895","https://openalex.org/W2036970834","https://openalex.org/W2046472030","https://openalex.org/W2061689435","https://openalex.org/W2073393662","https://openalex.org/W2085264076","https://openalex.org/W2091911441","https://openalex.org/W2097799141","https://openalex.org/W2099777949","https://openalex.org/W2118117686","https://openalex.org/W2121586719","https://openalex.org/W2128280931","https://openalex.org/W2130190421","https://openalex.org/W2136908804","https://openalex.org/W2138410233","https://openalex.org/W2156083383","https://openalex.org/W2165639949","https://openalex.org/W2168155849","https://openalex.org/W2469743998","https://openalex.org/W2599346687","https://openalex.org/W2738206265","https://openalex.org/W2791504486","https://openalex.org/W2803902579","https://openalex.org/W2903890698","https://openalex.org/W2994580096","https://openalex.org/W3087035427","https://openalex.org/W3109464951","https://openalex.org/W3162536984","https://openalex.org/W4233115441","https://openalex.org/W4367182969","https://openalex.org/W4384023312","https://openalex.org/W4400942858","https://openalex.org/W4404229883","https://openalex.org/W4412393983","https://openalex.org/W7214985619"],"related_works":["https://openalex.org/W4412393983","https://openalex.org/W7067050451","https://openalex.org/W1648713263","https://openalex.org/W2091551301","https://openalex.org/W2085264076","https://openalex.org/W4233115441","https://openalex.org/W2034928770","https://openalex.org/W2099777949","https://openalex.org/W4367182969","https://openalex.org/W3087035427"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1,135],"aim":[2],"of":[3,12,19,63,71,93,105,262,308],"the":[4,10,99,148],"present":[5],"study":[6],"was":[7,50,77,138,176,188,204,223,287],"to":[8,26,40,80],"investigate":[9],"prevalence":[11],"hypo-":[13],"and":[14,25,31,91,116,131,141,165,186,197,216,228,239,267,272,285,298,311],"hypercobalaminaemia":[15,299],"in":[16,178,206,212,259,290,302],"a":[17,41,47,189,217,305],"cohort":[18,261],"cats":[20,38,57,107,179,207,291,303],"with":[21,29,264,282,292,304],"diverse":[22],"disease":[23,32,94,314],"pathologies":[24],"assess":[27],"associations":[28,233,315],"signalment":[30],"characteristics.":[33],"METHODS:":[34],"Residual":[35],"blood":[36,59],"from":[37,98],"presented":[39],"large":[42],"veterinary":[43],"referral":[44],"hospital":[45],"during":[46],"24-month":[48],"period":[49],"used":[51],"for":[52,68],"serum":[53,155,170,173,198,201,229,237,274],"B12":[54,75,174,202,230,238,255,279],"quantification.":[55],"All":[56],"requiring":[58],"collection":[60],"as":[61,96],"part":[62],"diagnostic":[64],"investigations":[65],"were":[66,108,126,133,234,257,300,316],"eligible":[67],"inclusion":[69],"regardless":[70],"clinical":[72,100,309],"presentation.":[73],"Serum":[74,277],"concentration":[76,175,203,280],"assessed":[78],"according":[79],"signalment,":[81],"body":[82,84,89,143,226,242,246,293],"weight,":[83],"condition":[85,243],"score,":[86,244],"primary":[87],"affected":[88,245],"system":[90,247],"type":[92],"pathology":[95,249],"derived":[97],"notes.":[101],"RESULTS:":[102],"A":[103],"total":[104],"229":[106,149],"enrolled:":[109],"128":[110],"male":[111],"(119":[112],"neutered,":[113,120],"9":[114],"entire)":[115],"101":[117],"female":[118],"(88":[119],"13":[121],"entire).":[122],"Of":[123,147],"these,":[124],"176":[125],"domestic":[127],"shorthair":[128],"or":[129,248],"longhair,":[130],"53":[132],"purebred.":[134],"median":[136,142],"age":[137,196],"9.9":[139],"years":[140,182],"weight":[144,227],"4.1":[145],"kg.":[146,296],"cats,":[150,263],"80":[151],"(34.9%)":[152],"had":[153,159,163,168],"high":[154,271],"B12,":[156],"86":[157],"(37.6%)":[158],"normal,":[160],"18":[161],"(7.9%)":[162],"borderline":[164],"45":[166],"(19.7%)":[167],"low":[169,273],"B12.":[171,199],"Median":[172,200],"higher":[177],"aged":[180],"<8.0":[181],"than":[183,211],"\u2a7e8.0":[184],"years,":[185],"there":[187],"weak":[190,218],"but":[191,219],"significant":[192,220],"negative":[193],"correlation":[194,222],"between":[195,225,236],"lower":[205],"weighing":[208],"<3.0":[209,295],"kg":[210],"those":[213],"\u2a7e3.0":[214],"kg,":[215],"positive":[221],"found":[224,235],"concentration.":[231],"No":[232],"sex,":[240],"breed,":[241],"type.":[250],"CONCLUSIONS":[251],"AND":[252],"RELEVANCE:":[253],"Vitamin":[254],"aberrations":[256],"common":[258],"this":[260],"approximately":[265],"one-third":[266],"one-fifth":[268],"having":[269],"abnormally":[270],"concentrations,":[275],"respectively.":[276],"vitamin":[278],"declined":[281],"advancing":[283],"age,":[284],"hypocobalaminaemia":[286],"more":[288],"prevalent":[289],"weights":[294],"Hypo-":[297],"documented":[301],"wide":[306],"variety":[307],"presentations,":[310],"no":[312],"specific":[313],"elucidated.":[317]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-08-13T00:00:00"}