{"id":"https://openalex.org/W7202268765","doi":"https://doi.org/10.1007/s44411-026-00812-x","title":"Evaluation of Maternal Serum Erythropoietin Levels and Their Relationship with Surgical Bleeding in Placenta Previa and Placenta Accreta Spectrum Cases","display_name":"Evaluation of Maternal Serum Erythropoietin Levels and Their Relationship with Surgical Bleeding in Placenta Previa and Placenta Accreta Spectrum Cases","publication_year":2026,"publication_date":"2026-08-12","ids":{"openalex":"https://openalex.org/W7202268765","doi":"https://doi.org/10.1007/s44411-026-00812-x"},"language":"en","primary_location":{"id":"doi:10.1007/s44411-026-00812-x","doi":"https://doi.org/10.1007/s44411-026-00812-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s44411-026-00812-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s44411-026-00812-x.pdf","source":{"id":"https://openalex.org/S2756093218","display_name":"Bratislavsk\u00e9 lek\u00e1rske listy/Bratislava medical journal","issn_l":"0006-9248","issn":["0006-9248","1336-0345"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bratislava Medical Journal","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7202268765"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s44411-026-00812-x.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120591087","display_name":"Gokce Omeroglu Kay\u0131kc\u0131","orcid":"https://orcid.org/0000-0002-1371-1587","observed_orcids":["https://orcid.org/0000-0002-1371-1587"]},"institutions":[{"id":"https://openalex.org/I162720556","display_name":"Karadeniz Technical University","ror":"https://ror.org/03z8fyr40","country_code":"TR","type":"education","lineage":["https://openalex.org/I162720556"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Gokce Omeroglu Kayikci","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey","institution_ids":["https://openalex.org/I162720556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018120903","display_name":"G\u00fclseren Din\u00e7","orcid":"https://orcid.org/0000-0001-6513-0656","observed_orcids":["https://orcid.org/0000-0001-6513-0656","https://orcid.org/0000-0003-3627-8269"]},"institutions":[{"id":"https://openalex.org/I162720556","display_name":"Karadeniz Technical University","ror":"https://ror.org/03z8fyr40","country_code":"TR","type":"education","lineage":["https://openalex.org/I162720556"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Gulseren Dinc","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey"],"raw_orcid":"https://orcid.org/0000-0001-6513-0656","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey","institution_ids":["https://openalex.org/I162720556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153568778","display_name":"Huseyin Yaman","orcid":"https://orcid.org/0000-0003-4440-3912","observed_orcids":["https://orcid.org/0000-0003-4440-3912"]},"institutions":[{"id":"https://openalex.org/I162720556","display_name":"Karadeniz Technical University","ror":"https://ror.org/03z8fyr40","country_code":"TR","type":"education","lineage":["https://openalex.org/I162720556"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Huseyin Yaman","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey","institution_ids":["https://openalex.org/I162720556"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014829606","display_name":"S. Ayan","orcid":"https://orcid.org/0000-0002-4441-2723","observed_orcids":["https://orcid.org/0000-0002-4441-2723"]},"institutions":[{"id":"https://openalex.org/I162720556","display_name":"Karadeniz Technical University","ror":"https://ror.org/03z8fyr40","country_code":"TR","type":"education","lineage":["https://openalex.org/I162720556"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Sumeyye Sura Ayan","raw_affiliation_strings":["Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey","institution_ids":["https://openalex.org/I162720556"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053375027","display_name":"S\u00fcleyman G\u00fcven","orcid":"https://orcid.org/0000-0003-4832-4525","observed_orcids":["https://orcid.org/0000-0003-4832-4525"]},"institutions":[{"id":"https://openalex.org/I162720556","display_name":"Karadeniz Technical University","ror":"https://ror.org/03z8fyr40","country_code":"TR","type":"education","lineage":["https://openalex.org/I162720556"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Suleyman Guven","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, Trabzon, 61080, Turkey","institution_ids":["https://openalex.org/I162720556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5018120903"],"corresponding_institution_ids":["https://openalex.org/I162720556"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":{"value":3590,"currency":"USD","value_usd":3590},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11389","display_name":"Maternal and fetal healthcare","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11389","display_name":"Maternal and fetal healthcare","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":0.9330000281333923},{"id":"https://openalex.org/keywords/placenta-previa","display_name":"placenta previa","score":0.9829999804496765},{"id":"https://openalex.org/keywords/placenta-accreta-spectrum","display_name":"placenta accreta spectrum","score":1.0},{"id":"https://openalex.org/keywords/cesarean-section","display_name":"cesarean section","score":0.7730000019073486},{"id":"https://openalex.org/keywords/intraoperative-blood-loss","display_name":"intraoperative blood loss","score":0.8840000033378601},{"id":"https://openalex.org/keywords/surgical-bleeding","display_name":"surgical bleeding","score":0.703000009059906},{"id":"https://openalex.org/keywords/tissue-hypoxia","display_name":"tissue hypoxia","score":0.8809999823570251},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.75},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.5789999961853027},{"id":"https://openalex.org/keywords/blood-transfusion","display_name":"blood transfusion","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9314000010490417},{"id":"https://openalex.org/C2780081364","wikidata":"https://www.wikidata.org/wiki/Q1471410","display_name":"Placenta previa","level":5,"score":0.9275000095367432},{"id":"https://openalex.org/C2779116671","wikidata":"https://www.wikidata.org/wiki/Q517856","display_name":"Placenta accreta","level":5,"score":0.6499000191688538},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.583899974822998},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.506600022315979},{"id":"https://openalex.org/C2778534260","wikidata":"https://www.wikidata.org/wiki/Q218706","display_name":"Erythropoietin","level":2,"score":0.4729999899864197},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.46050000190734863},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.412200003862381},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3926999866962433},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.3490999937057495},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.323199987411499},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.3181000053882599},{"id":"https://openalex.org/C2909919656","wikidata":"https://www.wikidata.org/wiki/Q7200296","display_name":"Placenta Diseases","level":5,"score":0.3073999881744385},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.30469998717308044},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.2985999882221222},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.28700000047683716},{"id":"https://openalex.org/C3020128735","wikidata":"https://www.wikidata.org/wiki/Q228036","display_name":"Cesarean delivery","level":3,"score":0.2784999907016754}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s44411-026-00812-x","doi":"https://doi.org/10.1007/s44411-026-00812-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s44411-026-00812-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s44411-026-00812-x.pdf","source":{"id":"https://openalex.org/S2756093218","display_name":"Bratislavsk\u00e9 lek\u00e1rske listy/Bratislava medical journal","issn_l":"0006-9248","issn":["0006-9248","1336-0345"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bratislava Medical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1007/s44411-026-00812-x","doi":"https://doi.org/10.1007/s44411-026-00812-x","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s44411-026-00812-x","pdf_url":"https://link.springer.com/content/pdf/10.1007/s44411-026-00812-x.pdf","source":{"id":"https://openalex.org/S2756093218","display_name":"Bratislavsk\u00e9 lek\u00e1rske listy/Bratislava medical journal","issn_l":"0006-9248","issn":["0006-9248","1336-0345"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bratislava Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7202268765.pdf","grobid_xml":"https://content.openalex.org/works/W7202268765.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1910196207","https://openalex.org/W1933030459","https://openalex.org/W2022989210","https://openalex.org/W2034531626","https://openalex.org/W2045298552","https://openalex.org/W2058141781","https://openalex.org/W2073755020","https://openalex.org/W2078511758","https://openalex.org/W2082739679","https://openalex.org/W2092247900","https://openalex.org/W2099924208","https://openalex.org/W2110788486","https://openalex.org/W2139934338","https://openalex.org/W2156155600","https://openalex.org/W2159904075","https://openalex.org/W2296909678","https://openalex.org/W2461496653","https://openalex.org/W2766813744","https://openalex.org/W2791097462","https://openalex.org/W3047383690","https://openalex.org/W3126543351","https://openalex.org/W3209198273","https://openalex.org/W4214843556","https://openalex.org/W4285025118","https://openalex.org/W4318705679","https://openalex.org/W4319014625","https://openalex.org/W4389521535","https://openalex.org/W4415491073"],"related_works":["https://openalex.org/W7125638143","https://openalex.org/W2530917784","https://openalex.org/W2013499394","https://openalex.org/W2892881043","https://openalex.org/W4416844010","https://openalex.org/W2048872246","https://openalex.org/W7163205725","https://openalex.org/W4405010440","https://openalex.org/W7167806137","https://openalex.org/W4412371722"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"The":[2],"aim":[3],"of":[4,41,48,123,246],"this":[5,42],"study":[6,58],"was":[7,118],"to":[8,16,37],"examine":[9],"maternal":[10],"serum":[11,107,135],"erythropoietin":[12],"(EPO)":[13],"levels,":[14],"known":[15],"be":[17,235],"associated":[18],"with":[19,28],"tissue":[20,248],"hypoxia":[21,249],"and":[22,31,36,73,92,129,156,191,201,225,250],"angiogenesis,":[23],"in":[24,44,112,143,152,161,170,176,197,205,252],"pregnant":[25,61],"women":[26,62],"diagnosed":[27],"placenta":[29,32,81,145,172,199],"previa":[30,82,146,173,200],"accreta":[33],"spectrum":[34],"(PAS),":[35],"evaluate":[38],"the":[39,46,121,144,153,162,171,177,198,206,244,253],"role":[40],"biomarker":[43],"predicting":[45],"amount":[47],"surgical":[49],"bleeding":[50],"during":[51],"cesarean":[52,65,104],"section.":[53],"Method":[54],"This":[55],"prospective":[56],"case-control":[57],"included":[59],"100":[60],"who":[63],"underwent":[64],"delivery":[66],"at":[67],"a":[68,93,238],"tertiary":[69],"center":[70],"between":[71,221],"2022":[72],"2024.":[74],"Participants":[75],"were":[76,110,138,167,194],"divided":[77],"into":[78],"three":[79],"groups:":[80],"(":[83,88,96,180,209,228],"n":[84,89,97],"=":[85,90,98],"35),":[86],"PAS":[87,154,202],"14),":[91],"control":[94,163,178,207],"group":[95,174,179,208],"51)":[99],"scheduled":[100],"for":[101],"uncomplicated":[102],"elective":[103],"delivery.":[105],"Preoperative":[106],"EPO":[108,136,165,223,233],"levels":[109,137,166,224],"measured":[111],"all":[113],"cases.":[114],"Intraoperative":[115],"blood":[116],"loss":[117],"assessed":[119],"using":[120],"number":[122],"sponges/compresses":[124],"used,":[125],"suction":[126],"canister":[127,189],"volume,":[128],"transfusion":[130],"requirements.":[131],"Results":[132],"Mean":[133],"preoperative":[134,222],"32.6":[139],"\u00b1":[140,149,158],"27.2":[141],"U/L":[142,151,160],"group,":[147,155],"31.6":[148],"35.4":[150],"22.8":[157],"18.4":[159],"group.":[164],"significantly":[168,195],"higher":[169,196],"than":[175,204],"p":[181,210,229],"<":[182,211],"0.05).":[183,231],"As":[184],"expected,":[185],"bleeding-related":[186,226],"parameters":[187],"(suction":[188],"volume":[190],"sponge":[192],"count)":[193],"groups":[203],"0.001).":[212],"However,":[213],"correlation":[214],"analyses":[215],"revealed":[216],"no":[217],"statistically":[218],"significant":[219],"association":[220],"markers":[227],">":[230],"Conclusion":[232],"may":[234],"used":[236],"as":[237],"complementary":[239],"biological":[240],"marker":[241],"that":[242],"reflects":[243],"severity":[245],"underlying":[247],"hypervascularization":[251],"pathological":[254],"placenta.":[255]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-08-13T00:00:00"}