{"id":"https://openalex.org/W7202207980","doi":"https://doi.org/10.3390/ijms27198858","title":"Nanoscale Analysis of SSB\u2013RecO Interplay in SSB Interaction with the Target","display_name":"Nanoscale Analysis of SSB\u2013RecO Interplay in SSB Interaction with the Target","publication_year":2026,"publication_date":"2026-10-04","ids":{"openalex":"https://openalex.org/W7202207980","doi":"https://doi.org/10.3390/ijms27198858","pmid":"https://pubmed.ncbi.nlm.nih.gov/42884100","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13665497"},"language":"en","primary_location":{"id":"doi:10.3390/ijms27198858","doi":"https://doi.org/10.3390/ijms27198858","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms27198858","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/ijms27198858","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016007071","display_name":"Shivkumar Sharma Irukuvajjula","orcid":"https://orcid.org/0000-0003-3901-6213","observed_orcids":["https://orcid.org/0000-0003-3901-6213"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shivkumar Sharma Irukuvajjula","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3901-6213","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067440169","display_name":"Shaun Filliaux","orcid":"https://orcid.org/0000-0003-0462-5203","observed_orcids":["https://orcid.org/0000-0003-0462-5203"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shaun Filliaux","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0462-5203","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5020066689","display_name":"Yuri L. Lyubchenko","orcid":"https://orcid.org/0000-0001-9721-8302","observed_orcids":["https://orcid.org/0000-0001-9721-8302"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yuri L. Lyubchenko","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9721-8302","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5020066689"],"corresponding_institution_ids":[],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.45739465,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"19","first_page":"8858","last_page":"8858"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-stranded-dna-binding-protein","display_name":"single-stranded DNA binding protein","score":0.9769999980926514},{"id":"https://openalex.org/keywords/reco","display_name":"RecO","score":0.8700000047683716},{"id":"https://openalex.org/keywords/reca","display_name":"RecA","score":0.9520000219345093},{"id":"https://openalex.org/keywords/homologous-recombination","display_name":"homologous recombination","score":0.8209999799728394},{"id":"https://openalex.org/keywords/single-stranded-dna","display_name":"single-stranded DNA","score":0.8240000009536743},{"id":"https://openalex.org/keywords/protein-displacement","display_name":"protein displacement","score":0.6380000114440918},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.8050000071525574},{"id":"https://openalex.org/keywords/genome-maintenance","display_name":"genome maintenance","score":0.7979999780654907}],"concepts":[{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.6129000186920166},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5533000230789185},{"id":"https://openalex.org/C45206210","wikidata":"https://www.wikidata.org/wiki/Q2415817","display_name":"Nanoscopic scale","level":2,"score":0.46720001101493835},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4650000035762787},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.44179999828338623},{"id":"https://openalex.org/C138944611","wikidata":"https://www.wikidata.org/wiki/Q1163287","display_name":"Clearance","level":2,"score":0.42179998755455017},{"id":"https://openalex.org/C2781448156","wikidata":"https://www.wikidata.org/wiki/Q1570182","display_name":"Coating","level":2,"score":0.4068000018596649},{"id":"https://openalex.org/C102744134","wikidata":"https://www.wikidata.org/wiki/Q22280388","display_name":"Homologous recombination","level":3,"score":0.39899998903274536},{"id":"https://openalex.org/C11804247","wikidata":"https://www.wikidata.org/wiki/Q896177","display_name":"Protein\u2013protein interaction","level":2,"score":0.38499999046325684},{"id":"https://openalex.org/C51639874","wikidata":"https://www.wikidata.org/wiki/Q167149","display_name":"Plasma protein binding","level":2,"score":0.3785000145435333},{"id":"https://openalex.org/C102951782","wikidata":"https://www.wikidata.org/wiki/Q49295","display_name":"Atomic force microscopy","level":2,"score":0.37439998984336853},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.37139999866485596},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3578000068664551},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.34950000047683716},{"id":"https://openalex.org/C87716614","wikidata":"https://www.wikidata.org/wiki/Q845744","display_name":"Static electricity","level":2,"score":0.3321000039577484},{"id":"https://openalex.org/C119473381","wikidata":"https://www.wikidata.org/wiki/Q49298","display_name":"Force spectroscopy","level":3,"score":0.32600000500679016},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3183000087738037},{"id":"https://openalex.org/C2779179475","wikidata":"https://www.wikidata.org/wiki/Q3545649","display_name":"Decoy","level":3,"score":0.3138999938964844},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.31049999594688416},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.30390000343322754},{"id":"https://openalex.org/C156695909","wikidata":"https://www.wikidata.org/wiki/Q3373825","display_name":"Recombination","level":3,"score":0.2946999967098236},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.29120001196861267},{"id":"https://openalex.org/C174510640","wikidata":"https://www.wikidata.org/wiki/Q489618","display_name":"HEK 293 cells","level":3,"score":0.2856999933719635},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.28349998593330383},{"id":"https://openalex.org/C2781338088","wikidata":"https://www.wikidata.org/wiki/Q903495","display_name":"Residue (chemistry)","level":2,"score":0.27399998903274536},{"id":"https://openalex.org/C2107291","wikidata":"https://www.wikidata.org/wiki/Q14886885","display_name":"Mediator","level":2,"score":0.27230000495910645},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.26660001277923584},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.26409998536109924},{"id":"https://openalex.org/C111154242","wikidata":"https://www.wikidata.org/wiki/Q923545","display_name":"Spontaneous emission","level":3,"score":0.25690001249313354},{"id":"https://openalex.org/C2781285689","wikidata":"https://www.wikidata.org/wiki/Q21921428","display_name":"Crystal (programming language)","level":2,"score":0.2533999979496002},{"id":"https://openalex.org/C2781204021","wikidata":"https://www.wikidata.org/wiki/Q6497091","display_name":"Lattice (music)","level":2,"score":0.2517000138759613}],"mesh":[{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004277","descriptor_name":"DNA, Single-Stranded","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004277","descriptor_name":"DNA, Single-Stranded","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018625","descriptor_name":"Microscopy, Atomic Force","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/ijms27198858","doi":"https://doi.org/10.3390/ijms27198858","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms27198858","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"doi:10.20944/preprints202608.0663.v1","doi":"https://doi.org/10.20944/preprints202608.0663.v1","is_oa":true,"landing_page_url":"https://doi.org/10.20944/preprints202608.0663.v1","pdf_url":null,"source":{"id":"https://openalex.org/S6309402219","display_name":"Preprints.org","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:13665497","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13665497/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13665497/pdf/ijms-27-08858.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmid:42884100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42884100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:digitalcommons.unmc.edu:cop_pharmsci_articles-1058","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.unmc.edu/cop_pharmsci_articles/55","pdf_url":"https://digitalcommons.unmc.edu/context/cop_pharmsci_articles/article/1058/viewcontent/2026_Lyubchenko_IJMS.pdf","source":{"id":"https://openalex.org/S7407097584","display_name":"DigitalCommons@UNMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I59130452","host_organization_name":"University of Nebraska Medical Center","host_organization_lineage":["https://openalex.org/I59130452"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal Articles: Pharmaceutical Sciences","raw_type":"text"}],"best_oa_location":{"id":"doi:10.3390/ijms27198858","doi":"https://doi.org/10.3390/ijms27198858","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms27198858","pdf_url":null,"source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000862453","display_name":"Insight into the mechanism of action of the SSB interactome","funder_award_id":"R01GM144414","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7202207980.pdf","grobid_xml":"https://content.openalex.org/works/W7202207980.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W38956248","https://openalex.org/W1031578623","https://openalex.org/W1509078442","https://openalex.org/W1520909561","https://openalex.org/W1806123628","https://openalex.org/W1893642377","https://openalex.org/W1968810666","https://openalex.org/W1971178460","https://openalex.org/W1972379164","https://openalex.org/W1989108993","https://openalex.org/W2002333699","https://openalex.org/W2005548481","https://openalex.org/W2024922257","https://openalex.org/W2025223303","https://openalex.org/W2044016235","https://openalex.org/W2048092465","https://openalex.org/W2048727149","https://openalex.org/W2051864856","https://openalex.org/W2061713612","https://openalex.org/W2070461581","https://openalex.org/W2073534733","https://openalex.org/W2075442976","https://openalex.org/W2079230093","https://openalex.org/W2084530022","https://openalex.org/W2087174347","https://openalex.org/W2110730225","https://openalex.org/W2127979283","https://openalex.org/W2128923895","https://openalex.org/W2129719466","https://openalex.org/W2131737890","https://openalex.org/W2149870666","https://openalex.org/W2153436893","https://openalex.org/W2165932788","https://openalex.org/W2415270688","https://openalex.org/W2574055941","https://openalex.org/W2577399050","https://openalex.org/W2580692595","https://openalex.org/W2962311094","https://openalex.org/W3016488325","https://openalex.org/W3148042916","https://openalex.org/W4211195658","https://openalex.org/W4234188399","https://openalex.org/W4321377998","https://openalex.org/W4324018024","https://openalex.org/W4398172278","https://openalex.org/W4405926655","https://openalex.org/W4411097490","https://openalex.org/W4416535916"],"related_works":["https://openalex.org/W2087174347","https://openalex.org/W2189332315","https://openalex.org/W2025223303","https://openalex.org/W2334565024","https://openalex.org/W2043141017","https://openalex.org/W7164896633","https://openalex.org/W2283386156","https://openalex.org/W125305046","https://openalex.org/W2075442976","https://openalex.org/W1520909561"],"abstract_inverted_index":{"Single-stranded":[0],"DNA-binding":[1],"protein":[2,28],"(SSB)":[3],"coats":[4],"single-stranded":[5],"DNA":[6],"(ssDNA)":[7],"and":[8],"recruits":[9],"downstream":[10],"factors,":[11],"yet":[12],"this":[13,50],"same":[14],"coating":[15],"must":[16],"be":[17],"cleared":[18],"for":[19],"SSB-interacting":[20],"proteins":[21],"to":[22,36,48,90],"bind.":[23],"RecA":[24],"is":[25,46,154],"a":[26,42,82,106,129,133,169],"central":[27],"in":[29],"homologous":[30],"recombination,":[31],"which":[32],"requires":[33],"SSB-free":[34],"ssDNA":[35,84],"load":[37],"during":[38,175],"the":[39,62,97,110,157],"process.":[40],"RecO,":[41],"recombination":[43],"mediator":[44],"protein,":[45],"thought":[47],"regulate":[49],"handoff,":[51],"but":[52,126],"it":[53],"has":[54],"not":[55],"been":[56],"shown":[57],"directly":[58],"that":[59,74,119,138,150],"RecO":[60,75,124],"drives":[61],"release":[63],"of":[64,100,112],"full-length,":[65],"ssDNA-bound":[66],"SSB.":[67],"Using":[68],"atomic":[69],"force":[70],"microscopy,":[71],"we":[72],"show":[73,118],"actively":[76],"displaces":[77],"full-length":[78],"wild-type":[79],"SSB":[80,101,113,152,173],"from":[81,88],"defined":[83],"substrate,":[85],"reducing":[86],"occupancy":[87],"67%":[89],"29%.":[91],"Displacement":[92],"efficiency":[93],"decreases":[94],"after":[95,104],"deleting":[96],"C-terminal":[98],"tip":[99],"(\u0394C8)":[102],"or":[103],"adding":[105],"single":[107],"alanine":[108],"at":[109],"C-terminus":[111],"(A179).":[114],"Molecular":[115],"dynamics":[116],"simulations":[117],"A179":[120],"retains":[121],"its":[122],"native":[123],"contact":[125],"additionally":[127],"engages":[128],"non-native":[130],"surface,":[131],"producing":[132],"specific,":[134],"over-engaged":[135],"complex,":[136],"suggesting":[137],"these":[139,147],"interprotein":[140],"interactions":[141],"may":[142],"affect":[143],"SSB-ssDNA":[144],"contacts.":[145],"Together,":[146],"findings":[148],"suggest":[149],"RecO-driven":[151],"clearance":[153],"governed":[155],"by":[156,162],"protein\u2013protein":[158],"interface":[159],"rather":[160],"than":[161],"ssDNA-binding":[163],"affinity":[164],"alone,":[165],"thereby":[166],"acting":[167],"as":[168],"checkpoint":[170],"against":[171],"indiscriminate":[172],"removal":[174],"genome":[176],"maintenance.":[177]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-08-12T00:00:00"}