{"id":"https://openalex.org/W7202069137","doi":"https://doi.org/10.14744/tjtes.2026.17258","title":"Effects of topical Turkish propolis on burn wound healing in an experimental burn model","display_name":"Effects of topical Turkish propolis on burn wound healing in an experimental burn model","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7202069137","doi":"https://doi.org/10.14744/tjtes.2026.17258","pmid":"https://pubmed.ncbi.nlm.nih.gov/42593031","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13478495"},"language":"en","primary_location":{"id":"doi:10.14744/tjtes.2026.17258","doi":"https://doi.org/10.14744/tjtes.2026.17258","is_oa":true,"landing_page_url":"https://doi.org/10.14744/tjtes.2026.17258","pdf_url":"https://jag.journalagent.com/z5/download_fulltext.asp?pdir=travma&plng=eng&un=UTD-17258","source":{"id":"https://openalex.org/S2754011711","display_name":"Turkish Journal of Trauma and Emergency Surgery","issn_l":"1300-6738","issn":["1300-6738","1306-696X","1307-7945"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","poland-40","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4324032569","host_organization_name":"Turkish Association of Trauma and Emergency Surgery","host_organization_lineage":["https://openalex.org/P4324032569"],"host_organization_lineage_names":["Turkish Association of Trauma and Emergency Surgery"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Journal of Trauma and Emergency Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://jag.journalagent.com/z5/download_fulltext.asp?pdir=travma&plng=eng&un=UTD-17258","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023364516","display_name":"Esra Ardahan Akg\u00fcl","orcid":"https://orcid.org/0000-0003-3124-5679","observed_orcids":["https://orcid.org/0000-0003-3124-5679"]},"institutions":[{"id":"https://openalex.org/I250383648","display_name":"Izmir K\u00e2tip \u00c7elebi University","ror":"https://ror.org/024nx4843","country_code":"TR","type":"education","lineage":["https://openalex.org/I250383648"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Esra Ardahan Akg\u00fcl","raw_affiliation_strings":["Department of Nursing, \u0130zmir Katip \u00c7elebi University, Faculty of Health Sciences, \u0130zmir-T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nursing, \u0130zmir Katip \u00c7elebi University, Faculty of Health Sciences, \u0130zmir-T\u00fcrkiye","institution_ids":["https://openalex.org/I250383648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023973806","display_name":"Figen Yard\u0131mc\u0131","orcid":"https://orcid.org/0000-0002-1550-985X","observed_orcids":["https://orcid.org/0000-0002-1550-985X"]},"institutions":[{"id":"https://openalex.org/I41641357","display_name":"Ege University","ror":"https://ror.org/02eaafc18","country_code":"TR","type":"education","lineage":["https://openalex.org/I41641357"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Figen Yard\u0131mc\u0131","raw_affiliation_strings":["Department of Pediatric Nursing, Ege University Faculty of Nursing, \u0130zmir-T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Nursing, Ege University Faculty of Nursing, \u0130zmir-T\u00fcrkiye","institution_ids":["https://openalex.org/I41641357"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057495844","display_name":"Derya Demir","orcid":"https://orcid.org/0000-0002-6333-8856","observed_orcids":["https://orcid.org/0000-0002-6333-8856"]},"institutions":[{"id":"https://openalex.org/I41641357","display_name":"Ege University","ror":"https://ror.org/02eaafc18","country_code":"TR","type":"education","lineage":["https://openalex.org/I41641357"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Derya Demir","raw_affiliation_strings":["Department of Medical Pathology, Ege University Faculty of Medicine, \u0130zmir-T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Pathology, Ege University Faculty of Medicine, \u0130zmir-T\u00fcrkiye","institution_ids":["https://openalex.org/I41641357"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084024719","display_name":"Fahri Emrah Soylu","orcid":"https://orcid.org/0000-0002-8405-5468","observed_orcids":["https://orcid.org/0000-0002-8405-5468"]},"institutions":[{"id":"https://openalex.org/I41641357","display_name":"Ege University","ror":"https://ror.org/02eaafc18","country_code":"TR","type":"education","lineage":["https://openalex.org/I41641357"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Fahri Emrah Soylu","raw_affiliation_strings":["Ege University, Laboratory Animals Application and Research Center \u0130zmir-T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ege University, Laboratory Animals Application and Research Center \u0130zmir-T\u00fcrkiye","institution_ids":["https://openalex.org/I41641357"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023364516"],"corresponding_institution_ids":["https://openalex.org/I250383648"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.55536485,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"8","first_page":"895","last_page":"907"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/propolis","display_name":"propolis","score":0.7559999823570251},{"id":"https://openalex.org/keywords/burn-wound-healing","display_name":"burn wound healing","score":0.8640000224113464},{"id":"https://openalex.org/keywords/partial-thickness-burns","display_name":"second-degree burns","score":0.8190000057220459},{"id":"https://openalex.org/keywords/topical-wound-treatment","display_name":"topical wound treatment","score":0.6349999904632568},{"id":"https://openalex.org/keywords/silver-sulfadiazine","display_name":"silver sulfadiazine","score":0.9390000104904175},{"id":"https://openalex.org/keywords/nitrofurazone","display_name":"nitrofurazone","score":1.0},{"id":"https://openalex.org/keywords/collagen-deposition","display_name":"collagen deposition","score":0.7160000205039978},{"id":"https://openalex.org/keywords/fibroblast-proliferation","display_name":"fibroblast proliferation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/fibrosis","display_name":"fibrosis","score":0.9390000104904175},{"id":"https://openalex.org/keywords/mononuclear-cell-infiltration","display_name":"mononuclear cell infiltration","score":0.9330000281333923},{"id":"https://openalex.org/keywords/rat-burn-model","display_name":"rat burn model","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C2780488879","wikidata":"https://www.wikidata.org/wiki/Q184398","display_name":"Propolis","level":2,"score":0.727400004863739},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7222999930381775},{"id":"https://openalex.org/C3019879682","wikidata":"https://www.wikidata.org/wiki/Q170518","display_name":"Burn wound","level":3,"score":0.4880000054836273},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.4616999924182892},{"id":"https://openalex.org/C2781121862","wikidata":"https://www.wikidata.org/wiki/Q256","display_name":"Turkish","level":2,"score":0.41609999537467957},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3050000071525574},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.30169999599456787},{"id":"https://openalex.org/C2993242423","wikidata":"https://www.wikidata.org/wiki/Q170518","display_name":"Burn injury","level":2,"score":0.24789999425411224},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.219200000166893},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.2076999992132187}],"mesh":[{"descriptor_ui":"D000287","descriptor_name":"Administration, Topical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000891","descriptor_name":"Anti-Infective Agents, Local","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000891","descriptor_name":"Anti-Infective Agents, Local","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009583","descriptor_name":"Nitrofurazone","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D009583","descriptor_name":"Nitrofurazone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009583","descriptor_name":"Nitrofurazone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011429","descriptor_name":"Propolis","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D011429","descriptor_name":"Propolis","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011429","descriptor_name":"Propolis","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012837","descriptor_name":"Silver Sulfadiazine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D012837","descriptor_name":"Silver Sulfadiazine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012837","descriptor_name":"Silver Sulfadiazine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D014421","descriptor_name":"Turkey","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.14744/tjtes.2026.17258","doi":"https://doi.org/10.14744/tjtes.2026.17258","is_oa":true,"landing_page_url":"https://doi.org/10.14744/tjtes.2026.17258","pdf_url":"https://jag.journalagent.com/z5/download_fulltext.asp?pdir=travma&plng=eng&un=UTD-17258","source":{"id":"https://openalex.org/S2754011711","display_name":"Turkish Journal of Trauma and Emergency Surgery","issn_l":"1300-6738","issn":["1300-6738","1306-696X","1307-7945"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","poland-40","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4324032569","host_organization_name":"Turkish Association of Trauma and Emergency Surgery","host_organization_lineage":["https://openalex.org/P4324032569"],"host_organization_lineage_names":["Turkish Association of Trauma and Emergency Surgery"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Journal of Trauma and Emergency Surgery","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13478495","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13478495/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13478495/pdf/TJTES-32-895.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ulus Travma Acil Cerrahi Derg","raw_type":"Text"},{"id":"pmid:42593031","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42593031","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.14744/tjtes.2026.17258","doi":"https://doi.org/10.14744/tjtes.2026.17258","is_oa":true,"landing_page_url":"https://doi.org/10.14744/tjtes.2026.17258","pdf_url":"https://jag.journalagent.com/z5/download_fulltext.asp?pdir=travma&plng=eng&un=UTD-17258","source":{"id":"https://openalex.org/S2754011711","display_name":"Turkish Journal of Trauma and Emergency Surgery","issn_l":"1300-6738","issn":["1300-6738","1306-696X","1307-7945"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","poland-40","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4324032569","host_organization_name":"Turkish Association of Trauma and Emergency Surgery","host_organization_lineage":["https://openalex.org/P4324032569"],"host_organization_lineage_names":["Turkish Association of Trauma and Emergency Surgery"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Journal of Trauma and Emergency Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7202069137.pdf","grobid_xml":"https://content.openalex.org/works/W7202069137.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7216898898","https://openalex.org/W2737046341","https://openalex.org/W4406162112","https://openalex.org/W2890892691","https://openalex.org/W4417082297","https://openalex.org/W7124430612","https://openalex.org/W2301297141","https://openalex.org/W3168774986","https://openalex.org/W2106704635","https://openalex.org/W2395581958"],"abstract_inverted_index":{"BACKGROUND:":[0],"Burns":[1],"are":[2],"a":[3],"leading":[4],"cause":[5,28],"of":[6,29,41,173,187],"accident-related":[7],"mortality,":[8],"following":[9],"motor":[10],"vehicle":[11,157],"accidents":[12],"and":[13,27,37,52,87,106,111,140,144,146,149,155,179],"drowning.":[14],"Burn":[15],"wound":[16,59,107,119,134,198],"healing":[17,60],"is":[18],"influenced":[19],"by":[20],"several":[21],"factors,":[22],"including":[23],"the":[24,30,39,118,153,168],"degree,":[25],"depth,":[26],"burn.":[31],"This":[32],"study":[33],"aimed":[34],"to":[35,75,190,196],"compare":[36],"evaluate":[38],"effects":[40],"1%":[42],"silver":[43,79],"sulfadiazine,":[44,80],"0.2%":[45],"nitrofurazone,":[46,81],"propolis":[47,55,82,130,156,189],"vehicle,":[48,83],"10%":[49,84],"water-soluble":[50,54,85,89,129,188],"propolis,":[51,86],"15%":[53,88,128],"on":[56,103,136,162],"partial-thickness":[57],"burn":[58,96,191],"using":[61],"histopathological":[62,122],"assessment.":[63],"METHODS:":[64],"In":[65],"this":[66],"randomized":[67],"controlled":[68],"experimental":[69],"study,":[70],"rats":[71,194],"were":[72,93,101,109,115],"randomly":[73],"assigned":[74],"six":[76],"groups:":[77],"control,":[78],"propolis.":[90],"The":[91,185],"animals":[92],"anesthetized":[94],"before":[95],"induction.":[97],"Four":[98],"contact":[99],"burns":[100],"created":[102],"each":[104],"rat,":[105],"areas":[108,135],"measured":[110],"recorded.":[112],"Tissue":[113],"samples":[114],"collected":[116],"from":[117],"sites":[120],"for":[121],"examination.":[123],"RESULTS:":[124],"Rats":[125],"treated":[126],"with":[127,152],"had":[131],"significantly":[132],"smaller":[133],"days":[137],"7":[138],"(p=0.019":[139],"p=0.047),":[141],"14":[142,164],"(p=0.01":[143],"p=0.033),":[145],"21":[147],"(p=0.00":[148],"p=0.040)":[150],"compared":[151],"control":[154],"groups,":[158],"respectively.":[159],"Histopathological":[160],"evaluation":[161],"day":[163],"revealed":[165],"differences":[166],"favoring":[167],"propolis-treated":[169],"groups":[170],"in":[171,193],"terms":[172],"fibroblast":[174],"proliferation,":[175],"collagen":[176],"deposition,":[177],"fibrosis,":[178],"mononuclear":[180],"cell":[181],"infiltration":[182],"(p=0.017).":[183],"CONCLUSION:":[184],"application":[186],"wounds":[192],"appears":[195],"promote":[197],"healing.":[199]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-08-10T00:00:00"}