{"id":"https://openalex.org/W7202045683","doi":"https://doi.org/10.4328/acam.22867","title":"Discrimination between spinal meningioma and schwannoma using MRI machine learning-based radiomics texture analysis","display_name":"Discrimination between spinal meningioma and schwannoma using MRI machine learning-based radiomics texture analysis","publication_year":2025,"publication_date":"2025-11-11","ids":{"openalex":"https://openalex.org/W7202045683","doi":"https://doi.org/10.4328/acam.22867"},"language":"en","primary_location":{"id":"doi:10.4328/acam.22867","doi":"https://doi.org/10.4328/acam.22867","is_oa":true,"landing_page_url":"https://doi.org/10.4328/acam.22867","pdf_url":"https://doi.org/10.4328/acam.22867","source":{"id":"https://openalex.org/S4210235416","display_name":"The Annals of Clinical and Analytical Medicine","issn_l":"2667-663X","issn":["2667-663X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Clinical and Analytical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4328/acam.22867","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040288576","display_name":"Yasin Celal G\u00fcne\u015f","orcid":"https://orcid.org/0000-0001-7631-854X","observed_orcids":["https://orcid.org/0000-0001-7631-854X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasin Celal G\u00fcne\u015f","raw_affiliation_strings":["Clinic of Radiology, K\u0131r\u0131kkale Y\u00fcksek \u0130htisas Hospital, K\u0131r\u0131kkale, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0001-7631-854X","affiliations":[{"raw_affiliation_string":"Clinic of Radiology, K\u0131r\u0131kkale Y\u00fcksek \u0130htisas Hospital, K\u0131r\u0131kkale, T\u00fcrkiye","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056914759","display_name":"Semra Duran","orcid":"https://orcid.org/0000-0003-0863-2443","observed_orcids":["https://orcid.org/0000-0003-0863-2443","https://orcid.org/0000-0003-2170-0914"]},"institutions":[{"id":"https://openalex.org/I4399598363","display_name":"Ankara Bilkent City Hospital","ror":"https://ror.org/033fqnp11","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4399598363"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Semra Duran","raw_affiliation_strings":["Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0003-2170-0914","affiliations":[{"raw_affiliation_string":"Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I4399598363"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060124173","display_name":"Karabek\u0131r Ercan","orcid":"https://orcid.org/0000-0002-4812-3371","observed_orcids":["https://orcid.org/0000-0002-4812-3371"]},"institutions":[{"id":"https://openalex.org/I4399598363","display_name":"Ankara Bilkent City Hospital","ror":"https://ror.org/033fqnp11","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4399598363"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Karabekir Ercan","raw_affiliation_strings":["Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0002-4812-3371","affiliations":[{"raw_affiliation_string":"Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I4399598363"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046913301","display_name":"Ebru \u00d6zt\u00fcrk","orcid":"https://orcid.org/0000-0001-9206-6856","observed_orcids":["https://orcid.org/0000-0001-9206-6856"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ebru \u00d6zt\u00fcrk","raw_affiliation_strings":["Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0001-9206-6856","affiliations":[{"raw_affiliation_string":"Department of Biostatistics, Faculty of Medicine, Hacettepe University, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022308500","display_name":"Pinar \u0130lhan Demir","orcid":"https://orcid.org/0000-0003-4020-1360","observed_orcids":["https://orcid.org/0000-0003-4020-1360"]},"institutions":[{"id":"https://openalex.org/I4399598363","display_name":"Ankara Bilkent City Hospital","ror":"https://ror.org/033fqnp11","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4399598363"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"P\u0131nar \u0130lhan Demir","raw_affiliation_strings":["Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0003-4020-1360","affiliations":[{"raw_affiliation_string":"Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I4399598363"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092173346","display_name":"G\u00fcls\u00fcm K\u00fcbra Bahad\u0131r","orcid":"https://orcid.org/0000-0003-1894-9372","observed_orcids":["https://orcid.org/0000-0003-1894-9372"]},"institutions":[{"id":"https://openalex.org/I4399598363","display_name":"Ankara Bilkent City Hospital","ror":"https://ror.org/033fqnp11","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4399598363"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"G\u00fcls\u00fcm K\u00fcbra Bahad\u0131r","raw_affiliation_strings":["Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0003-1894-9372","affiliations":[{"raw_affiliation_string":"Department of Radiology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I4399598363"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036736916","display_name":"\u00d6zge Ba\u015faran Aydo\u011fdu","orcid":"https://orcid.org/0000-0002-2554-929X","observed_orcids":["https://orcid.org/0000-0002-2554-929X"]},"institutions":[{"id":"https://openalex.org/I4399598363","display_name":"Ankara Bilkent City Hospital","ror":"https://ror.org/033fqnp11","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4399598363"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"\u00d6zge Ba\u015faran Aydo\u011fdu","raw_affiliation_strings":["Department of Pathology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye"],"raw_orcid":"https://orcid.org/0000-0002-2554-929X","affiliations":[{"raw_affiliation_string":"Department of Pathology, Ankara Bilkent City Hospital, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I4399598363"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.53410475,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"8","first_page":"793","last_page":"798"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spinal-meningioma","display_name":"spinal meningioma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/schwannoma","display_name":"schwannoma","score":0.9399999976158142},{"id":"https://openalex.org/keywords/radiomics","display_name":"radiomics","score":0.7699999809265137},{"id":"https://openalex.org/keywords/texture-analysis","display_name":"texture analysis","score":0.9110000133514404},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.7829999923706055},{"id":"https://openalex.org/keywords/tumor-differentiation","display_name":"tumor differentiation","score":0.5609999895095825},{"id":"https://openalex.org/keywords/dural-tail-sign","display_name":"dural tail sign","score":0.8600000143051147},{"id":"https://openalex.org/keywords/spinal-cord-compression","display_name":"spinal cord compression","score":0.972000002861023},{"id":"https://openalex.org/keywords/preoperative-diagnosis","display_name":"preoperative diagnosis","score":0.796999990940094},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"support vector machine","score":0.8980000019073486}],"concepts":[{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.8495000004768372},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7652999758720398},{"id":"https://openalex.org/C2781447767","wikidata":"https://www.wikidata.org/wiki/Q369148","display_name":"Schwannoma","level":2,"score":0.65420001745224},{"id":"https://openalex.org/C2779160599","wikidata":"https://www.wikidata.org/wiki/Q369157","display_name":"Meningioma","level":2,"score":0.6330999732017517},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5379999876022339},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.4271000027656555},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.4099000096321106},{"id":"https://openalex.org/C3020132585","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic accuracy","level":2,"score":0.4004000127315521},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.39719998836517334},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3707999885082245},{"id":"https://openalex.org/C2778934081","wikidata":"https://www.wikidata.org/wiki/Q1981345","display_name":"Neuroma","level":2,"score":0.35030001401901245},{"id":"https://openalex.org/C2776507482","wikidata":"https://www.wikidata.org/wiki/Q7577474","display_name":"Spinal cord tumor","level":3,"score":0.30630001425743103},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.2651999890804291},{"id":"https://openalex.org/C71472368","wikidata":"https://www.wikidata.org/wiki/Q676880","display_name":"Text mining","level":2,"score":0.25200000405311584},{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.251800000667572}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.4328/acam.22867","doi":"https://doi.org/10.4328/acam.22867","is_oa":true,"landing_page_url":"https://doi.org/10.4328/acam.22867","pdf_url":"https://doi.org/10.4328/acam.22867","source":{"id":"https://openalex.org/S4210235416","display_name":"The Annals of Clinical and Analytical Medicine","issn_l":"2667-663X","issn":["2667-663X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Clinical and Analytical Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.4328/acam.22867","doi":"https://doi.org/10.4328/acam.22867","is_oa":true,"landing_page_url":"https://doi.org/10.4328/acam.22867","pdf_url":"https://doi.org/10.4328/acam.22867","source":{"id":"https://openalex.org/S4210235416","display_name":"The Annals of Clinical and Analytical Medicine","issn_l":"2667-663X","issn":["2667-663X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Clinical and Analytical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7202045683.pdf","grobid_xml":"https://content.openalex.org/works/W7202045683.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1789547851","https://openalex.org/W1968406433","https://openalex.org/W1983183612","https://openalex.org/W2972165905","https://openalex.org/W2992085171","https://openalex.org/W3029385710","https://openalex.org/W3034035069","https://openalex.org/W3204030525","https://openalex.org/W4223892213","https://openalex.org/W4251609090","https://openalex.org/W4292528167","https://openalex.org/W4293661044","https://openalex.org/W4368342591","https://openalex.org/W4389939099","https://openalex.org/W4396955460"],"related_works":["https://openalex.org/W4396955460","https://openalex.org/W7203901910","https://openalex.org/W4395001753","https://openalex.org/W7168022793","https://openalex.org/W4404591551","https://openalex.org/W3198250778","https://openalex.org/W7162305756","https://openalex.org/W2912122972","https://openalex.org/W4410487701","https://openalex.org/W3029385710"],"abstract_inverted_index":{"Aim":[0],"To":[1],"identify":[2],"radiomics":[3,95,161,247,261],"parameters":[4],"that":[5],"distinguish":[6],"spinal":[7,25,52,151,256],"meningiomas":[8,257],"from":[9,75,258],"schwannomas":[10],"and":[11,30,59,79,90,97,150,195,217,241,278],"evaluate":[12],"machine":[13],"learning":[14],"models":[15,87],"using":[16,65,92],"MRI":[17,38,250],"data.":[18],"Methods":[19],"Patients":[20],"with":[21,107,230,248],"histopathologic":[22],"diagnoses":[23],"of":[24,130,185,189,193,198,207,211,215,220,233,236,239,243],"meningioma":[26,112],"(n":[27,32],"=":[28,33,116,127,142,148],"25)":[29],"schwannoma":[31],"26)":[34],"who":[35],"underwent":[36],"pre-surgical":[37],"were":[39,63,73,88,173],"enrolled.":[40],"Semantic":[41],"features,":[42,96],"including":[43],"tumor":[44,124],"location,":[45],"longest":[46,123],"diameter,":[47],"foraminal":[48],"extension,":[49],"cystic":[50,139],"changes,":[51],"cord":[53,152],"compression,":[54],"enhancement":[55],"patterns,":[56],"dural":[57,132],"tail,":[58],"ginkgo":[60,144],"leaf":[61,145],"signs,":[62],"assessed":[64],"a":[66,131,191,196,213,218,263],"single":[67],"3.0":[68],"T":[69],"scanner.":[70],"Radiomics":[71],"features":[72],"extracted":[74,160],"T1-weighted,":[76],"T2-weighted,":[77],"STIR,":[78],"post-gadolinium":[80],"T1-weighted":[81],"images.":[82],"Support":[83],"Vector":[84],"Machine":[85],"(SVM)":[86],"trained":[89],"validated":[91],"conventional":[93,249],"MRI,":[94],"their":[98],"combination.":[99],"Results":[100],"A":[101],"significant":[102,119],"gender":[103],"difference":[104],"was":[105],"found,":[106],"more":[108],"females":[109],"in":[110,254],"the":[111,122,158,227],"group":[113],"(84%,":[114],"P":[115],".039).":[117],"Other":[118],"factors":[120],"included":[121],"dimension":[125],"(P":[126,135,141,147,154],".03),":[128],"presence":[129],"tail":[133],"sign":[134,146],"<":[136,155],".001),":[137],"intratumoral":[138],"changes":[140],".003),":[143],".01),":[149],"compression":[153],".001).":[156],"Of":[157],"444":[159],"parameters,":[162],"186":[163],"demonstrated":[164,226],"good":[165],"reproducibility":[166],"(ICC":[167],"\u2265":[168],"0.75).":[169],"Among":[170],"these,":[171],"49":[172],"retained":[174],"for":[175,267],"model":[176],"construction.":[177],"Model":[178,200,222],"1":[179],"(conventional":[180],"MRI)":[181],"achieved":[182,204],"an":[183,187,205,209,231],"AUC":[184,206,232],"0.902,":[186],"accuracy":[188,210,235,253],"0.882,":[190],"sensitivity":[192,214,238],"0.884,":[194],"specificity":[197,219,242],"0.880.":[199],"2":[201],"(radiomics":[202],"features)":[203,225],"0.909,":[208],"0.843,":[212],"0.961,":[216],"0.720.":[221],"3":[223],"(combined":[224],"highest":[228],"performance":[229],"0.997,":[234],"0.960,":[237],"1.000,":[240],"0.920.":[244],"Conclusion":[245],"Combining":[246],"improves":[251],"diagnostic":[252],"differentiating":[255],"schwannomas,":[259],"supporting":[260],"as":[262],"valuable":[264],"non-invasive":[265],"tool":[266],"preoperative":[268],"diagnosis.":[269],"Multicenter":[270],"studies":[271],"are":[272],"needed":[273],"to":[274],"validate":[275],"these":[276],"findings":[277],"expand":[279],"clinical":[280],"applications.":[281]},"counts_by_year":[],"updated_date":"2026-10-26T11:51:55.731654","created_date":"2026-08-10T00:00:00"}