{"id":"https://openalex.org/W7202033223","doi":"https://doi.org/10.1016/j.fochx.2026.104298","title":"Comparative enzymatic hydrolysis of porcine tracheal cartilage generates ACE/DPP-IV-inhibitory and antioxidant peptides with enhanced bioactivity following simulated gastrointestinal digestion and molecular docking analysis","display_name":"Comparative enzymatic hydrolysis of porcine tracheal cartilage generates ACE/DPP-IV-inhibitory and antioxidant peptides with enhanced bioactivity following simulated gastrointestinal digestion and molecular docking analysis","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7202033223","doi":"https://doi.org/10.1016/j.fochx.2026.104298","pmid":"https://pubmed.ncbi.nlm.nih.gov/42643162","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13503080"},"language":"en","primary_location":{"id":"doi:10.1016/j.fochx.2026.104298","doi":"https://doi.org/10.1016/j.fochx.2026.104298","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.fochx.2026.104298","pdf_url":null,"source":{"id":"https://openalex.org/S4210189394","display_name":"Food Chemistry X","issn_l":"2590-1575","issn":["2590-1575"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry: X","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.fochx.2026.104298","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000541284","display_name":"Rayudika Aprilia Patindra Purba","orcid":"https://orcid.org/0000-0003-4672-1455","observed_orcids":["https://orcid.org/0000-0003-4672-1455"]},"institutions":[{"id":"https://openalex.org/I131868736","display_name":"Prince of Songkla University","ror":"https://ror.org/0575ycz84","country_code":"TH","type":"education","lineage":["https://openalex.org/I131868736"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Rayudika Aprilia Patindra Purba","raw_affiliation_strings":["Department of Agricultural Science and Technology, Faculty of Innovative Agriculture, Fisheries and Food, Prince of Songkla University, Surat Thani Campus, Surat Thani, 84000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Agricultural Science and Technology, Faculty of Innovative Agriculture, Fisheries and Food, Prince of Songkla University, Surat Thani Campus, Surat Thani, 84000, Thailand","institution_ids":["https://openalex.org/I131868736"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121594607","display_name":"Suchanya Sinsranoi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Suchanya Sinsranoi","raw_affiliation_strings":["Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","Research and Development Institute Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"Research and Development Institute Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088349705","display_name":"Phanthipha Laosam","orcid":"https://orcid.org/0000-0003-1684-338X","observed_orcids":["https://orcid.org/0000-0003-1684-338X"]},"institutions":[{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Phanthipha Laosam","raw_affiliation_strings":["Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","Research and Development Institute Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"Research and Development Institute Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121568242","display_name":"Phornpilat Senanok","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Phornpilat Senanok","raw_affiliation_strings":["Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094299833","display_name":"Pichitpon Luasiri","orcid":"https://orcid.org/0009-0007-2332-324X","observed_orcids":["https://orcid.org/0009-0007-2332-324X"]},"institutions":[{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Pichitpon Luasiri","raw_affiliation_strings":["Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032523109","display_name":"Pornphutthachat Sota","orcid":"https://orcid.org/0000-0002-7170-2056","observed_orcids":["https://orcid.org/0000-0002-7170-2056"]},"institutions":[{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Pornphutthachat Sota","raw_affiliation_strings":["School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117414168","display_name":"Nattapol Pongsamai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405278044","display_name":"Suranaree University of Technology Hospital","ror":"https://ror.org/04rhj5p56","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4405278044"]},{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Nattapol Pongsamai","raw_affiliation_strings":["Suranaree University of Technology Hospital, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Suranaree University of Technology Hospital, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I4405278044","https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026854542","display_name":"Saranya Suwanangul","orcid":"https://orcid.org/0000-0003-4096-3285","observed_orcids":["https://orcid.org/0000-0003-4096-3285"]},"institutions":[{"id":"https://openalex.org/I190734841","display_name":"Maejo University","ror":"https://ror.org/03c7s1f64","country_code":"TH","type":"education","lineage":["https://openalex.org/I190734841"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Saranya Suwanangul","raw_affiliation_strings":["Program in Food Science and Technology, Faculty of Engineering and Agro-industry, Maejo University, Chiang Mai 50290, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program in Food Science and Technology, Faculty of Engineering and Agro-industry, Maejo University, Chiang Mai 50290, Thailand","institution_ids":["https://openalex.org/I190734841"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029933434","display_name":"Jukkrapong Pinyo","orcid":"https://orcid.org/0000-0001-8483-3138","observed_orcids":["https://orcid.org/0000-0001-8483-3138"]},"institutions":[{"id":"https://openalex.org/I198105771","display_name":"Kasetsart University","ror":"https://ror.org/05gzceg21","country_code":"TH","type":"education","lineage":["https://openalex.org/I198105771"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Jukkrapong Pinyo","raw_affiliation_strings":["Faculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom 73140, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom 73140, Thailand","institution_ids":["https://openalex.org/I198105771"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023686422","display_name":"Sasikan Katemala","orcid":"https://orcid.org/0000-0003-3187-474X","observed_orcids":["https://orcid.org/0000-0003-3187-474X"]},"institutions":[{"id":"https://openalex.org/I198105771","display_name":"Kasetsart University","ror":"https://ror.org/05gzceg21","country_code":"TH","type":"education","lineage":["https://openalex.org/I198105771"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sasikan Katemala","raw_affiliation_strings":["Faculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom 73140, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Agriculture at Kamphaeng Saen, Kasetsart University, Kamphaeng Saen Campus, Nakhon Pathom 73140, Thailand","institution_ids":["https://openalex.org/I198105771"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100504310","display_name":"Saruttiwong Boonkong","orcid":"https://orcid.org/0009-0004-2079-7034","observed_orcids":["https://orcid.org/0009-0004-2079-7034"]},"institutions":[{"id":"https://openalex.org/I4210150485","display_name":"Loei Rajabhat University","ror":"https://ror.org/04p9hvh53","country_code":"TH","type":"education","lineage":["https://openalex.org/I4210150485"]},{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Saruttiwong Boonkong","raw_affiliation_strings":["Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","Program in Animal Science, Faculty of Science and Technology, Loei Rajabhat University, Loei 42000, Thailand","School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"Program in Animal Science, Faculty of Science and Technology, Loei Rajabhat University, Loei 42000, Thailand","institution_ids":["https://openalex.org/I4210150485"]},{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000616411","display_name":"Kamonpan Sanachai","orcid":"https://orcid.org/0000-0003-2605-5360","observed_orcids":["https://orcid.org/0000-0003-2605-5360"]},"institutions":[{"id":"https://openalex.org/I179193067","display_name":"Khon Kaen University","ror":"https://ror.org/03cq4gr50","country_code":"TH","type":"education","lineage":["https://openalex.org/I179193067"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Kamonpan Sanachai","raw_affiliation_strings":["Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand","institution_ids":["https://openalex.org/I179193067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065196814","display_name":"Papungkorn Sangsawad","orcid":"https://orcid.org/0000-0003-2420-8634","observed_orcids":["https://orcid.org/0000-0003-2420-8634"]},"institutions":[{"id":"https://openalex.org/I82475049","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78","country_code":"TH","type":"education","lineage":["https://openalex.org/I82475049"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Papungkorn Sangsawad","raw_affiliation_strings":["Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Postharvest Technology and Innovation in Animal Unit, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]},{"raw_affiliation_string":"School of Animal Technology and Innovation, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand","institution_ids":["https://openalex.org/I82475049"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5065196814"],"corresponding_institution_ids":["https://openalex.org/I82475049"],"apc_list":{"value":2330,"currency":"USD","value_usd":2330},"apc_paid":{"value":2330,"currency":"USD","value_usd":2330},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":null,"first_page":"104298","last_page":"104298"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13551","display_name":"Biochemical effects in animals","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enzymatic-hydrolysis","display_name":"enzymatic hydrolysis","score":0.925000011920929},{"id":"https://openalex.org/keywords/bioactive-peptides","display_name":"bioactive peptides","score":0.7049999833106995},{"id":"https://openalex.org/keywords/ace-inhibitory-peptides","display_name":"ACE inhibitory peptides","score":0.8289999961853027},{"id":"https://openalex.org/keywords/dpp-iv-inhibitory-peptides","display_name":"DPP-IV inhibitory peptides","score":0.9990000128746033},{"id":"https://openalex.org/keywords/antioxidant-peptides","display_name":"antioxidant peptides","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-ii-collagen","display_name":"type II collagen","score":0.6620000004768372},{"id":"https://openalex.org/keywords/neutrase","display_name":"Neutrase","score":0.6259999871253967},{"id":"https://openalex.org/keywords/papain","display_name":"papain","score":0.9919999837875366},{"id":"https://openalex.org/keywords/gastrointestinal-digestion","display_name":"gastrointestinal digestion","score":0.6050000190734863},{"id":"https://openalex.org/keywords/peptide-stability","display_name":"peptide stability","score":0.5849999785423279},{"id":"https://openalex.org/keywords/zinc-coordination","display_name":"zinc coordination","score":0.5649999976158142},{"id":"https://openalex.org/keywords/peptide-bioactivity","display_name":"peptide bioactivity","score":0.3479999899864197}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7461000084877014},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5692999958992004},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5577999949455261},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.49079999327659607},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.49059998989105225},{"id":"https://openalex.org/C53270655","wikidata":"https://www.wikidata.org/wiki/Q5381536","display_name":"Enzymatic hydrolysis","level":3,"score":0.42649999260902405},{"id":"https://openalex.org/C2781357212","wikidata":"https://www.wikidata.org/wiki/Q5275608","display_name":"Digestion (alchemy)","level":2,"score":0.4050000011920929},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.37040001153945923},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.361299991607666},{"id":"https://openalex.org/C2910669755","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide mapping","level":4,"score":0.2662000060081482},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.25049999356269836}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.fochx.2026.104298","doi":"https://doi.org/10.1016/j.fochx.2026.104298","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.fochx.2026.104298","pdf_url":null,"source":{"id":"https://openalex.org/S4210189394","display_name":"Food Chemistry X","issn_l":"2590-1575","issn":["2590-1575"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry: X","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13503080","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13503080/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13503080/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chem X","raw_type":"Text"},{"id":"pmid:42643162","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42643162","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food chemistry: X","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:833ca3e27070443a954e1531b85e0c79","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/833ca3e27070443a954e1531b85e0c79","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Food Chemistry: X, Vol 38, Iss , Pp 104298- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.fochx.2026.104298","doi":"https://doi.org/10.1016/j.fochx.2026.104298","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.fochx.2026.104298","pdf_url":null,"source":{"id":"https://openalex.org/S4210189394","display_name":"Food Chemistry X","issn_l":"2590-1575","issn":["2590-1575"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl","poland-40"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Chemistry: X","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4660619869","display_name":null,"funder_award_id":"12-02","funder_id":"https://openalex.org/F4320322574","funder_display_name":"Suranaree University of Technology"}],"funders":[{"id":"https://openalex.org/F4320322574","display_name":"Suranaree University of Technology","ror":"https://ror.org/05sgb8g78"},{"id":"https://openalex.org/F4320322692","display_name":"Prince of Songkla University","ror":"https://ror.org/0575ycz84"},{"id":"https://openalex.org/F4320329659","display_name":"Thailand Science Research and Innovation","ror":"https://ror.org/000025p04"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7202033223.pdf","grobid_xml":"https://content.openalex.org/works/W7202033223.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1971399433","https://openalex.org/W1989806335","https://openalex.org/W1998836648","https://openalex.org/W2005457909","https://openalex.org/W2028981036","https://openalex.org/W2044797131","https://openalex.org/W2081739151","https://openalex.org/W2160446463","https://openalex.org/W2168526937","https://openalex.org/W2263626787","https://openalex.org/W2511352978","https://openalex.org/W2562792957","https://openalex.org/W2782235836","https://openalex.org/W2793245154","https://openalex.org/W2920925854","https://openalex.org/W2924180394","https://openalex.org/W3091955990","https://openalex.org/W4224871221","https://openalex.org/W4312195502","https://openalex.org/W4384522273","https://openalex.org/W4385479377","https://openalex.org/W4390921219","https://openalex.org/W4399721943","https://openalex.org/W4401217543","https://openalex.org/W4401484224","https://openalex.org/W4402555017","https://openalex.org/W4404500262","https://openalex.org/W4404545143","https://openalex.org/W4405088449","https://openalex.org/W4406199930","https://openalex.org/W4406214263","https://openalex.org/W4406227562","https://openalex.org/W4407553595","https://openalex.org/W4409329807","https://openalex.org/W4410380507","https://openalex.org/W4410876651","https://openalex.org/W4413827191","https://openalex.org/W4414148674","https://openalex.org/W4415552422","https://openalex.org/W4416866220","https://openalex.org/W4417312865","https://openalex.org/W7101417735","https://openalex.org/W7117552877","https://openalex.org/W7130081762","https://openalex.org/W7138041001"],"related_works":["https://openalex.org/W2969932167","https://openalex.org/W4399403688","https://openalex.org/W3005253242","https://openalex.org/W2782235836","https://openalex.org/W2316144885","https://openalex.org/W2112988960","https://openalex.org/W2562792957","https://openalex.org/W2038678674","https://openalex.org/W7168168972","https://openalex.org/W2010781353"],"abstract_inverted_index":{"Porcine":[0],"tracheal":[1,130],"cartilage,":[2],"an":[3],"underutilized":[4],"Type":[5],"II":[6],"collagen-rich":[7],"by-product,":[8],"was":[9],"systematically":[10],"evaluated":[11],"as":[12,64,76,88,132],"a":[13,133],"source":[14,135],"of":[15,136],"angiotensin":[16],"I-converting":[17],"enzyme":[18],"(ACE)":[19],"inhibitory,":[20,24],"dipeptidyl":[21],"peptidase-IV":[22],"(DPP-IV)":[23],"and":[25,37,86,105,111,121],"antioxidant":[26,38,91,122],"peptides.":[27,39,141],"Neutrase":[28],"at":[29],"4":[30],"h":[31],"outperformed":[32],"Papain":[33],"in":[34,46],"generating":[35],"ACE-inhibitory":[36],"The":[40],"<3":[41],"kDa":[42],"ultrafiltration":[43],"fraction,":[44],"enriched":[45],"small":[47],"hydrophobic":[48],"peptides,":[49],"exhibited":[50],"the":[51,65,77,89],"highest":[52],"bioactivities.":[53],"LC-MS/MS":[54],"identified":[55],"eight":[56],"sequences":[57],"(870\u20131565":[58],"Da).":[59],"Chemical":[60],"synthesis":[61],"confirmed":[62],"LGLGADMFHR":[63,99],"most":[66],"potent":[67],"ACE":[68,119],"inhibitor":[69,80],"(IC":[70,81],"50":[71,82],"=":[72,83],"0.52":[73],"mM),":[74,85],"QGLPGPGAVAEYT":[75],"lead":[78],"DPP-IV":[79,125],"1.84":[84],"LGFGADRAGPQ":[87],"strongest":[90],"(5.64":[92],"mM":[93],"Trolox":[94],"equivalents).":[95],"Molecular":[96],"docking":[97],"revealed":[98],"binding":[100],"through":[101],"Zn":[102],"2+":[103],"coordination":[104],"hydrogen":[106],"bonds":[107],"with":[108],"Cys352,":[109],"Glu376,":[110],"Asp453.":[112],"Standardised":[113],"INFOGEST":[114],"gastrointestinal":[115],"digestion":[116],"progressively":[117],"enhanced":[118],"inhibition":[120,126],"activities":[123],"while":[124],"declined,":[127],"establishing":[128],"porcine":[129],"cartilage":[131],"viable":[134],"gastrointestinally":[137],"stable":[138],"cardiovascular":[139],"bioactive":[140]},"counts_by_year":[],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2026-08-10T00:00:00"}