{"id":"https://openalex.org/W7201860262","doi":"https://doi.org/10.1002/gcc.70157","title":"Chondroid Soft Tissue Tumors With FOS :: PABPN1 Fusion: A New Entity? About Two Cases","display_name":"Chondroid Soft Tissue Tumors With FOS :: PABPN1 Fusion: A New Entity? About Two Cases","publication_year":2026,"publication_date":"2026-08-01","ids":{"openalex":"https://openalex.org/W7201860262","doi":"https://doi.org/10.1002/gcc.70157","pmid":"https://pubmed.ncbi.nlm.nih.gov/42565647","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13449868"},"language":"en","primary_location":{"id":"doi:10.1002/gcc.70157","doi":"https://doi.org/10.1002/gcc.70157","is_oa":true,"landing_page_url":"https://doi.org/10.1002/gcc.70157","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/gcc.70157","source":{"id":"https://openalex.org/S200862508","display_name":"Genes Chromosomes and Cancer","issn_l":"1045-2257","issn":["1045-2257","1098-2264"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, Chromosomes and Cancer","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/gcc.70157","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003385491","display_name":"Jinane Kharmoum","orcid":"https://orcid.org/0009-0009-9661-6865","observed_orcids":["https://orcid.org/0009-0009-9661-6865"]},"institutions":[{"id":"https://openalex.org/I240042149","display_name":"Abdelmalek Essa\u00e2di University","ror":"https://ror.org/03c4shz64","country_code":"MA","type":"education","lineage":["https://openalex.org/I240042149"]},{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]}],"countries":["FR","MA"],"is_corresponding":true,"raw_author_name":"Jinane Kharmoum","raw_affiliation_strings":["Department of Biopathology Centre Leon Berard  Lyon France","Preclinical Basic Sciences Laboratory, Faculty of Medicine and Pharmacy of Tangiers Abdelmalek Essaadi University  Tetouan Morocco"],"raw_orcid":"https://orcid.org/0009-0009-9661-6865","affiliations":[{"raw_affiliation_string":"Department of Biopathology Centre Leon Berard  Lyon France","institution_ids":["https://openalex.org/I4210105738"]},{"raw_affiliation_string":"Preclinical Basic Sciences Laboratory, Faculty of Medicine and Pharmacy of Tangiers Abdelmalek Essaadi University  Tetouan Morocco","institution_ids":["https://openalex.org/I240042149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5145945746","display_name":"Alexendra Meurgey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]},{"id":"https://openalex.org/I4210125048","display_name":"Centre de Recherche en Canc\u00e9rologie de Lyon","ror":"https://ror.org/02mgw3155","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Alexendra Meurgey","raw_affiliation_strings":["Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","Department of Biopathology Centre Leon Berard  Lyon France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]},{"raw_affiliation_string":"Department of Biopathology Centre Leon Berard  Lyon France","institution_ids":["https://openalex.org/I4210105738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084291360","display_name":"Daniel Pissaloux","orcid":"https://orcid.org/0000-0003-1118-950X","observed_orcids":["https://orcid.org/0000-0003-1118-950X"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]},{"id":"https://openalex.org/I4210125048","display_name":"Centre de Recherche en Canc\u00e9rologie de Lyon","ror":"https://ror.org/02mgw3155","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel pissaloux","raw_affiliation_strings":["Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","Department of Biopathology Centre Leon Berard  Lyon France"],"raw_orcid":"https://orcid.org/0000-0003-1118-950X","affiliations":[{"raw_affiliation_string":"Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]},{"raw_affiliation_string":"Department of Biopathology Centre Leon Berard  Lyon France","institution_ids":["https://openalex.org/I4210105738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112559262","display_name":"S.A Chaib","orcid":"https://orcid.org/0009-0000-0640-5891","observed_orcids":["https://orcid.org/0009-0000-0640-5891"]},"institutions":[{"id":"https://openalex.org/I240042149","display_name":"Abdelmalek Essa\u00e2di University","ror":"https://ror.org/03c4shz64","country_code":"MA","type":"education","lineage":["https://openalex.org/I240042149"]},{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]}],"countries":["FR","MA"],"is_corresponding":false,"raw_author_name":"Sanae Chaib","raw_affiliation_strings":["Department of Biopathology Centre Leon Berard  Lyon France","Preclinical Basic Sciences Laboratory, Faculty of Medicine and Pharmacy of Tangiers Abdelmalek Essaadi University  Tetouan Morocco"],"raw_orcid":"https://orcid.org/0009-0000-0640-5891","affiliations":[{"raw_affiliation_string":"Department of Biopathology Centre Leon Berard  Lyon France","institution_ids":["https://openalex.org/I4210105738"]},{"raw_affiliation_string":"Preclinical Basic Sciences Laboratory, Faculty of Medicine and Pharmacy of Tangiers Abdelmalek Essaadi University  Tetouan Morocco","institution_ids":["https://openalex.org/I240042149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036634814","display_name":"Nicolas Macagno","orcid":"https://orcid.org/0000-0002-9882-2162","observed_orcids":["https://orcid.org/0000-0002-9882-2162"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]},{"id":"https://openalex.org/I4210162909","display_name":"H\u00f4pital de la Timone","ror":"https://ror.org/05jrr4320","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087487","https://openalex.org/I4210162909"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicolas Macagno","raw_affiliation_strings":["Department of Pathology and Neuropathology La Timone Hospital  Marseille France","INSERM MMG Aix Marseille University  Marseille France"],"raw_orcid":"https://orcid.org/0000-0002-9882-2162","affiliations":[{"raw_affiliation_string":"Department of Pathology and Neuropathology La Timone Hospital  Marseille France","institution_ids":["https://openalex.org/I4210162909"]},{"raw_affiliation_string":"INSERM MMG Aix Marseille University  Marseille France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I21491767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112690038","display_name":"Mariame Chra\u00efbi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I240042149","display_name":"Abdelmalek Essa\u00e2di University","ror":"https://ror.org/03c4shz64","country_code":"MA","type":"education","lineage":["https://openalex.org/I240042149"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mariame Chraibi","raw_affiliation_strings":["Preclinical Basic Sciences Laboratory, Faculty of Medicine and Pharmacy of Tangiers Abdelmalek Essaadi University  Tetouan Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Preclinical Basic Sciences Laboratory, Faculty of Medicine and Pharmacy of Tangiers Abdelmalek Essaadi University  Tetouan Morocco","institution_ids":["https://openalex.org/I240042149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062656683","display_name":"Franck Tirode","orcid":"https://orcid.org/0000-0003-4731-7817","observed_orcids":["https://orcid.org/0000-0003-4731-7817"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]},{"id":"https://openalex.org/I4210125048","display_name":"Centre de Recherche en Canc\u00e9rologie de Lyon","ror":"https://ror.org/02mgw3155","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Franck Tirode","raw_affiliation_strings":["Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France"],"raw_orcid":"https://orcid.org/0000-0003-4731-7817","affiliations":[{"raw_affiliation_string":"Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082141306","display_name":"Marie Karanian","orcid":"https://orcid.org/0000-0003-0434-636X","observed_orcids":["https://orcid.org/0000-0003-0434-636X"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210105738","display_name":"Centre L\u00e9on B\u00e9rard","ror":"https://ror.org/01cmnjq37","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210105738"]},{"id":"https://openalex.org/I4210125048","display_name":"Centre de Recherche en Canc\u00e9rologie de Lyon","ror":"https://ror.org/02mgw3155","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie Karanian","raw_affiliation_strings":["Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","Department of Biopathology Centre Leon Berard  Lyon France"],"raw_orcid":"https://orcid.org/0000-0003-0434-636X","affiliations":[{"raw_affiliation_string":"Centre de Recherche en Canc\u00e9rologie de Lyon, INSERM U1052 \u2010 CNRS UMR5286, Centre L\u00e9on B\u00e9rard Universit\u00e9 Lyon 1  Lyon France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210105738","https://openalex.org/I4210125048"]},{"raw_affiliation_string":"Department of Biopathology Centre Leon Berard  Lyon France","institution_ids":["https://openalex.org/I4210105738"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5003385491"],"corresponding_institution_ids":["https://openalex.org/I240042149","https://openalex.org/I4210105738"],"apc_list":{"value":4810,"currency":"USD","value_usd":4810},"apc_paid":{"value":4810,"currency":"USD","value_usd":4810},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.54213338,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"65","issue":"8","first_page":"e70157","last_page":"e70157"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.7196999788284302,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.7196999788284302,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.24369999766349792,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11991","display_name":"Soft tissue tumor case studies","score":0.014000000432133675,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-fusion","display_name":"gene fusion","score":0.6079999804496765},{"id":"https://openalex.org/keywords/synovial-chondromatosis","display_name":"synovial chondromatosis","score":0.8610000014305115},{"id":"https://openalex.org/keywords/rna-sequencing","display_name":"RNA sequencing","score":0.4410000145435333},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.8240000009536743},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.7129999995231628},{"id":"https://openalex.org/keywords/mesenchymal-tumors","display_name":"mesenchymal tumors","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7038000226020813},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6340000033378601},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.5149000287055969},{"id":"https://openalex.org/C136948725","wikidata":"https://www.wikidata.org/wiki/Q1458306","display_name":"Soft tissue","level":2,"score":0.5055999755859375},{"id":"https://openalex.org/C111829193","wikidata":"https://www.wikidata.org/wiki/Q1108970","display_name":"Fusion gene","level":3,"score":0.49390000104904175},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.46070000529289246},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.350600004196167},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.3366999924182892},{"id":"https://openalex.org/C2992511266","wikidata":"https://www.wikidata.org/wiki/Q1093098","display_name":"Gene rearrangement","level":3,"score":0.3305000066757202},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.33000001311302185},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.28929999470710754},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.26499998569488525},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2581000030040741}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012983","descriptor_name":"Soft Tissue Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012983","descriptor_name":"Soft Tissue Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015514","descriptor_name":"Oncogene Proteins, Fusion","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016760","descriptor_name":"Proto-Oncogene Proteins c-fos","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/gcc.70157","doi":"https://doi.org/10.1002/gcc.70157","is_oa":true,"landing_page_url":"https://doi.org/10.1002/gcc.70157","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/gcc.70157","source":{"id":"https://openalex.org/S200862508","display_name":"Genes Chromosomes and Cancer","issn_l":"1045-2257","issn":["1045-2257","1098-2264"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, Chromosomes and Cancer","raw_type":"journal-article"},{"id":"pmid:42565647","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42565647","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, chromosomes & cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13449868","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13449868/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes Chromosomes Cancer","raw_type":"Text"},{"id":"pmh:oai:HAL:hal-05721913v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-05721913","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genes, Chromosomes & Cancer, 2026, 65 (8), pp.e70157. ⟨10.1002/gcc.70157⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1002/gcc.70157","doi":"https://doi.org/10.1002/gcc.70157","is_oa":true,"landing_page_url":"https://doi.org/10.1002/gcc.70157","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/gcc.70157","source":{"id":"https://openalex.org/S200862508","display_name":"Genes Chromosomes and Cancer","issn_l":"1045-2257","issn":["1045-2257","1098-2264"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genes, Chromosomes and Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7201860262.pdf","grobid_xml":"https://content.openalex.org/works/W7201860262.grobid-xml"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W1775510683","https://openalex.org/W2000246857","https://openalex.org/W2008432341","https://openalex.org/W2052653618","https://openalex.org/W2118680832","https://openalex.org/W2955064419","https://openalex.org/W2980082240","https://openalex.org/W3006671071","https://openalex.org/W3127921804","https://openalex.org/W3136258228","https://openalex.org/W4210374156","https://openalex.org/W4210681710","https://openalex.org/W4213283526","https://openalex.org/W4284975272","https://openalex.org/W4288066698","https://openalex.org/W4323316540","https://openalex.org/W4385655358","https://openalex.org/W4386251100","https://openalex.org/W4399195053","https://openalex.org/W4399605243","https://openalex.org/W4401800480","https://openalex.org/W4413202680","https://openalex.org/W7116665298"],"related_works":["https://openalex.org/W2955064419","https://openalex.org/W3136258228","https://openalex.org/W4400736137","https://openalex.org/W4406291269","https://openalex.org/W4408800977","https://openalex.org/W7169497797","https://openalex.org/W4391652468","https://openalex.org/W4312114492","https://openalex.org/W4386251100","https://openalex.org/W7172443094"],"abstract_inverted_index":{"Soft":[0],"tissue":[1],"tumors":[2,37,60,157],"with":[3,10,49,93],"chondroid":[4,25,36,124,159,184,198],"matrix":[5],"represent":[6,218],"a":[7,39,177,219],"heterogeneous":[8],"group":[9],"persistent":[11],"diagnostic":[12,221],"challenges.":[13],"Advances":[14],"in":[15,23,55,83,110,155,194,200],"molecular":[16,180],"diagnostics":[17],"have":[18],"identified":[19,103],"recurrent":[20],"gene":[21,140],"fusions":[22],"several":[24],"neoplasms,":[26],"predominantly":[27],"involving":[28],"FN1.":[29],"Here,":[30],"we":[31],"report":[32],"two":[33],"cases":[34,66,118],"of":[35,129,134,152,167,182,191,197,215],"harboring":[38],"novel":[40],"FOS::PABPN1":[41,107,162],"fusion.":[42],"The":[43,161,212],"patients":[44],"were":[45,61,79],"young":[46],"and":[47,63,69,91,99,122,172,175],"presented":[48,67],"small,":[50],"deep,":[51],"peri-osseous":[52],"nodules":[53],"located":[54],"the":[56,59,117,127,135,149,165,189,195],"extremities.":[57],"Histologically,":[58],"well-circumscribed":[62],"lobulated.":[64],"Both":[65],"fibro-cartilaginous":[68],"spindle":[70],"cell":[71],"areas.":[72],"No":[73],"cytonuclear":[74],"atypia,":[75],"mitoses,":[76],"or":[77,208,210],"necrosis":[78],"observed.":[80,143],"Immunohistochemistry":[81],"(performed":[82],"Case":[84],"2)":[85],"revealed":[86],"positivity":[87],"for":[88,95],"S100,":[89],"CD34,":[90],"FOS,":[92],"negativity":[94],"MDM2,":[96],"HMGA2,":[97],"PLAG1,":[98],"desmin.":[100],"RNA":[101,192],"sequencing":[102,193],"an":[104],"identical":[105],"in-frame":[106],"fusion":[108,163],"transcript":[109],"both":[111],"tumors.":[112,185],"Unsupervised":[113],"transcriptomic":[114],"clustering":[115],"positioned":[116],"near":[119],"synovial":[120],"chondromatoses":[121],"other":[123],"lesions,":[125],"despite":[126],"absence":[128],"FN1":[130],"rearrangements.":[131],"Massive":[132],"overexpression":[133],"WIF1":[136,216],"(Wnt":[137],"Inhibitory":[138],"Factor1)":[139],"was":[141],"also":[142],"To":[144],"our":[145],"knowledge,":[146],"this":[147],"is":[148],"first":[150],"description":[151],"FOS":[153],"rearrangement":[154,204],"mesenchymal":[156],"exhibiting":[158],"differentiation.":[160],"expands":[164],"spectrum":[166],"FOS-altered":[168],"neoplasms":[169,199],"beyond":[170],"osteoblastic":[171],"vascular":[173],"lesions":[174],"defines":[176],"potential":[178,220],"new":[179],"subset":[181],"benign":[183],"These":[186],"findings":[187],"highlight":[188],"utility":[190],"diagnosis":[196],"order":[201],"to":[202],"identify":[203],"(of":[205],"FN1,":[206],"THBS1":[207],"FOS)":[209],"IDH1/2.":[211],"consistent":[213],"upregulation":[214],"may":[217],"biomarker.":[222]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-08-08T00:00:00"}