{"id":"https://openalex.org/W7199169335","doi":null,"title":"Predittori di recidiva delle aritmie atriali post ablazione transcatetere in pazienti con cardiopatia congenita dell'adulto","display_name":"Predittori di recidiva delle aritmie atriali post ablazione transcatetere in pazienti con cardiopatia congenita dell'adulto","publication_year":2026,"publication_date":"2026-06-18","ids":{"openalex":"https://openalex.org/W7199169335"},"language":"it","primary_location":{"id":"pmh:oai:etd.adm.unipi.it:etd-05302026-142102","doi":null,"is_oa":true,"landing_page_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/","pdf_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/unrestricted/Tesi_Simi_Giulia.PdfA.pdf","source":{"id":"https://openalex.org/S4306401800","display_name":"Electronic Theses and Dissertations Repository (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/","raw_type":"text"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/unrestricted/Tesi_Simi_Giulia.PdfA.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057311887","display_name":"Giulia Simi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"SIMI, GIULIA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5057311887"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.6000999808311462,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.6000999808311462,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10300","display_name":"Congenital Heart Disease Studies","score":0.19859999418258667,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.16740000247955322,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arrhythmia-recurrence","display_name":"arrhythmia recurrence","score":0.9160000085830688},{"id":"https://openalex.org/keywords/radiofrequency-catheter-ablation","display_name":"radiofrequency catheter ablation","score":0.925000011920929},{"id":"https://openalex.org/keywords/adult-congenital-heart-disease","display_name":"adult congenital heart disease","score":0.968999981880188},{"id":"https://openalex.org/keywords/atrial-tachyarrhythmia","display_name":"atrial tachyarrhythmia","score":0.7710000276565552},{"id":"https://openalex.org/keywords/macroreentrant-atrial-tachycardia","display_name":"macroreentrant atrial tachycardia","score":0.9539999961853027},{"id":"https://openalex.org/keywords/atrioventricular-nodal-reentrant-tachycardia","display_name":"atrioventricular nodal reentrant tachycardia","score":0.8820000290870667},{"id":"https://openalex.org/keywords/atrioventricular-reentrant-tachycardia","display_name":"atrioventricular reentrant tachycardia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/focal-atrial-tachycardia","display_name":"focal atrial tachycardia","score":0.9309999942779541},{"id":"https://openalex.org/keywords/atrial-flutter","display_name":"atrial flutter","score":0.4830000102519989},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.7630000114440918},{"id":"https://openalex.org/keywords/predictors-of-recurrence","display_name":"predictors of recurrence","score":0.43299999833106995},{"id":"https://openalex.org/keywords/cardiac-magnetic-resonance","display_name":"cardiac magnetic resonance","score":0.6570000052452087},{"id":"https://openalex.org/keywords/cardiopulmonary-exercise-testing","display_name":"cardiopulmonary exercise testing","score":0.9169999957084656},{"id":"https://openalex.org/keywords/exercise-induced-arrhythmia","display_name":"exercise-induced arrhythmia","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9480999708175659},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.6646999716758728},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6096000075340271},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6047999858856201},{"id":"https://openalex.org/C2780813298","wikidata":"https://www.wikidata.org/wiki/Q2071287","display_name":"Percutaneous","level":2,"score":0.5088000297546387},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.48969998955726624},{"id":"https://openalex.org/C2776131983","wikidata":"https://www.wikidata.org/wiki/Q436572","display_name":"Catheter ablation","level":3,"score":0.48410001397132874},{"id":"https://openalex.org/C80093799","wikidata":"https://www.wikidata.org/wiki/Q366155","display_name":"Intracardiac injection","level":2,"score":0.3986000120639801},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.3937000036239624},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.3718000054359436},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.3596999943256378},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.359499990940094},{"id":"https://openalex.org/C2776661526","wikidata":"https://www.wikidata.org/wiki/Q1361515","display_name":"Heart block","level":3,"score":0.33570000529289246},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3294999897480011},{"id":"https://openalex.org/C3018349756","wikidata":"https://www.wikidata.org/wiki/Q436572","display_name":"Radiofrequency catheter ablation","level":4,"score":0.326200008392334},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.296099990606308},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.29409998655319214},{"id":"https://openalex.org/C2776008845","wikidata":"https://www.wikidata.org/wiki/Q5038325","display_name":"Cardiac magnetic resonance imaging","level":3,"score":0.29179999232292175},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.2865000069141388},{"id":"https://openalex.org/C2777377203","wikidata":"https://www.wikidata.org/wiki/Q1809554","display_name":"Radiofrequency ablation","level":3,"score":0.27950000762939453},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.26159998774528503},{"id":"https://openalex.org/C2777093960","wikidata":"https://www.wikidata.org/wiki/Q594446","display_name":"Implantable cardioverter-defibrillator","level":2,"score":0.2606000006198883},{"id":"https://openalex.org/C2781267111","wikidata":"https://www.wikidata.org/wiki/Q652297","display_name":"Catheter","level":2,"score":0.25929999351501465},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2524999976158142}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:etd.adm.unipi.it:etd-05302026-142102","doi":null,"is_oa":true,"landing_page_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/","pdf_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/unrestricted/Tesi_Simi_Giulia.PdfA.pdf","source":{"id":"https://openalex.org/S4306401800","display_name":"Electronic Theses and Dissertations Repository (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:etd.adm.unipi.it:etd-05302026-142102","doi":null,"is_oa":true,"landing_page_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/","pdf_url":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/unrestricted/Tesi_Simi_Giulia.PdfA.pdf","source":{"id":"https://openalex.org/S4306401800","display_name":"Electronic Theses and Dissertations Repository (University of Pisa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I108290504","host_organization_name":"University of Pisa","host_organization_lineage":["https://openalex.org/I108290504"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://etd.adm.unipi.it/theses/available/etd-05302026-142102/","raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7199169335.pdf","grobid_xml":"https://content.openalex.org/works/W7199169335.grobid-xml"},"referenced_works_count":99,"referenced_works":["https://openalex.org/W44429629","https://openalex.org/W1652793678","https://openalex.org/W1672480111","https://openalex.org/W1786923028","https://openalex.org/W1850125129","https://openalex.org/W1926910606","https://openalex.org/W1968733770","https://openalex.org/W1994766630","https://openalex.org/W1995076163","https://openalex.org/W2061341959","https://openalex.org/W2067789291","https://openalex.org/W2075290555","https://openalex.org/W2083156242","https://openalex.org/W2086113600","https://openalex.org/W2095913721","https://openalex.org/W2107432762","https://openalex.org/W2115669561","https://openalex.org/W2120288035","https://openalex.org/W2141449330","https://openalex.org/W2166024847","https://openalex.org/W2166457346","https://openalex.org/W2167465286","https://openalex.org/W2170448649","https://openalex.org/W2170674246","https://openalex.org/W2171562935","https://openalex.org/W2183371114","https://openalex.org/W2216624238","https://openalex.org/W2285404792","https://openalex.org/W2324544907","https://openalex.org/W2402487074","https://openalex.org/W2408609101","https://openalex.org/W2427094903","https://openalex.org/W2546955765","https://openalex.org/W2595040062","https://openalex.org/W2601051244","https://openalex.org/W2609619995","https://openalex.org/W2617245041","https://openalex.org/W2630458705","https://openalex.org/W2744522626","https://openalex.org/W2745308627","https://openalex.org/W2759050434","https://openalex.org/W2790433953","https://openalex.org/W2807169357","https://openalex.org/W2850726970","https://openalex.org/W2886640324","https://openalex.org/W2901940932","https://openalex.org/W2901954321","https://openalex.org/W2911503861","https://openalex.org/W2918094628","https://openalex.org/W2942807636","https://openalex.org/W2953494408","https://openalex.org/W2955076039","https://openalex.org/W2980662162","https://openalex.org/W2981361985","https://openalex.org/W2998198440","https://openalex.org/W3002652237","https://openalex.org/W3032908438","https://openalex.org/W3035409924","https://openalex.org/W3082168186","https://openalex.org/W3087161218","https://openalex.org/W3111509417","https://openalex.org/W3121059217","https://openalex.org/W3156973490","https://openalex.org/W3190351271","https://openalex.org/W3193077165","https://openalex.org/W3195876153","https://openalex.org/W4210570701","https://openalex.org/W4220691971","https://openalex.org/W4236429281","https://openalex.org/W4283649743","https://openalex.org/W4283718439","https://openalex.org/W4283810652","https://openalex.org/W4293217384","https://openalex.org/W4293217392","https://openalex.org/W4306320460","https://openalex.org/W4310112817","https://openalex.org/W4321793485","https://openalex.org/W4328051744","https://openalex.org/W4365514322","https://openalex.org/W4367320217","https://openalex.org/W4375866227","https://openalex.org/W4382600568","https://openalex.org/W4382602732","https://openalex.org/W4385186970","https://openalex.org/W4385644664","https://openalex.org/W4386413166","https://openalex.org/W4390756772","https://openalex.org/W4393146885","https://openalex.org/W4394873258","https://openalex.org/W4399295557","https://openalex.org/W4400359666","https://openalex.org/W4402206023","https://openalex.org/W4403808134","https://openalex.org/W4404193870","https://openalex.org/W4410453536","https://openalex.org/W4410546196","https://openalex.org/W4414862386","https://openalex.org/W7119488862","https://openalex.org/W7126184467"],"related_works":["https://openalex.org/W7165890732","https://openalex.org/W3164493341","https://openalex.org/W2911503861","https://openalex.org/W7223559293","https://openalex.org/W2792061085","https://openalex.org/W2901954321","https://openalex.org/W2095883232","https://openalex.org/W4321793485","https://openalex.org/W2715188587","https://openalex.org/W1994766630"],"abstract_inverted_index":{"Introduction":[0],"-":[1,106,248,504],"Congenital":[2,36],"heart":[3,25,54,278,560,569],"disease":[4,26,279],"represents":[5],"the":[6,31,51,64,80,91,108,125,165,169,172,178,182,190,219,232,243,262,286,296,345,363,368,389,392,403,416,451,458,508,513,527,536,545,554,558,589,592,601,608],"most":[7,287],"common":[8],"congenital":[9,24,277],"defect.":[10],"Thanks":[11],"to":[12,44,78,341,492,603],"advances":[13],"in":[14,102,128,171,308,315,322,331,348,484,520,533,563,612],"medicine":[15],"and":[16,57,82,99,122,130,140,143,154,181,318,379,402,436,473,595,607],"cardiac":[17,149,236,530],"surgery,":[18],"over":[19],"90%":[20],"of":[21,33,46,53,85,93,110,145,168,174,177,184,186,210,221,234,253,265,274,283,333,357,380,391,424,453,462,507,516,529,538,549,557,574,591,610],"patients":[22,113,195,256,324,338,347,369,485,522,564],"with":[23,35,90,196,257,281,370,420,486,494,600],"now":[27],"reach":[28],"adulthood,":[29],"entering":[30],"cohort":[32],"Adults":[34],"Heart":[37],"Disease":[38],"(ACHD).":[39],"Atrial":[40],"arrhythmias,":[41],"affecting":[42],"up":[43],"50%":[45],"ACHD":[47,103,255,521],"patients,":[48,300],"significantly":[49,418,480],"increase":[50],"risk":[52,423],"failure":[55],"(HF)":[56],"mortality.":[58],"Radiofrequency":[59],"catheter":[60],"ablation":[61,179,519],"(RFCA)":[62],"is":[63,523],"first-line":[65],"therapy,":[66],"but":[67],"its":[68],"long-term":[69,191,514],"efficacy":[70,192,204,515],"remains":[71],"variable.":[72],"The":[73,202,249,505,571],"present":[74,509],"study":[75,250,510],"therefore":[76,582],"aims":[77],"identify":[79],"clinical":[81,98,139,605],"instrumental":[83,141],"predictors":[84],"arrhythmic":[86,222,371,406],"recurrence":[87,209,223,425],"after":[88,362],"RFCA,":[89],"goal":[92],"achieving":[94],"a":[95,258,271,376,385,421,479,487],"more":[96],"personalized":[97,597],"therapeutic":[100,598],"management":[101],"patients.":[104],"Methods":[105],"In":[107],"context":[109],"this":[111,613],"study,":[112],"who":[114],"underwent":[115,136,148,375,384],"RFCA":[116,365],"for":[117,584],"atrial":[118,211,292,305,319,358,438,455,496,517,540,576],"arrhythmias":[119,212,359],"between":[120],"2007":[121],"2025":[123],"at":[124,218,231,242,261],"Fondazione":[126],"Monasterio":[127],"Pisa":[129],"Massa":[131],"were":[132,200,295,339,360,399],"retrospectively":[133],"enrolled.":[134],"Patients":[135],"standard":[137],"baseline":[138,225],"evaluations,":[142],"some":[144],"them":[146],"also":[147,467],"magnetic":[150],"resonance":[151],"(CMR)":[152],"imaging":[153,580],"cardiopulmonary":[155],"exercise":[156],"testing":[157],"(CPET).":[158],"Acute":[159,326],"procedural":[160,198,327,350],"success":[161,199,328,351],"was":[162,206,216,329,352,409,457,466],"defined":[163],"as":[164,285,544],"intraprocedural":[166],"termination":[167],"arrhythmia,":[170],"presence":[173,452,537],"bidirectional":[175],"block":[176],"lines":[180],"absence":[183],"inducibility":[185],"sustained":[187],"tachyarrhythmias.":[188],"For":[189],"analysis,":[193,415],"only":[194,459,546],"acute":[197],"considered.":[201],"primary":[203],"endpoint":[205],"freedom":[207,404],"from":[208,405],"during":[213],"follow-up.":[214,342],"Follow-up":[215],"censored":[217],"detection":[220],"on":[224,344],"ECG":[226],"or":[227,238,241],"24-hour":[228],"Holter":[229],"monitoring,":[230],"time":[233,483],"any":[235],"surgical":[237],"percutaneous":[239],"intervention,":[240,594],"last":[244],"available":[245],"visit.":[246],"Results":[247],"population,":[251],"consisting":[252],"79":[254],"mean":[259],"age":[260],"first":[263,364],"EPS":[264],"46.03":[266],"\u00b1":[267],"15.97":[268],"years,":[269],"showed":[270,478],"clear":[272],"prevalence":[273],"moderate":[275],"complexity":[276],"(74.68%),":[280],"Tetralogy":[282],"Fallot":[284],"frequent":[288],"diagnosis":[289],"(60.76%).":[290],"Macroreentrant":[291],"tachycardias":[293,313],"(MRAT)":[294],"predominant":[297],"form":[298],"(56":[299],"70.8%),":[301],"followed":[302],"by":[303,443,469,526,535,567],"focal":[304],"tachycardia":[306],"(FAT)":[307],"10":[309],"(12.7%),":[310],"atrioventricular":[311],"reentrant":[312],"(AVNRT/AVRT)":[314],"7":[316],"(8.9%),":[317],"fibrillation":[320],"(AF)":[321],"6":[323],"(7.6%).":[325],"achieved":[330],"83.5%":[332],"cases":[334],"(66":[335],"patients);":[336],"3":[337],"lost":[340],"Focusing":[343],"63":[346,396],"whom":[349],"achieved,":[353],"35":[354],"(55.6%)":[355],"recurrences":[356],"documented":[361],"procedure.":[366],"Among":[367],"recurrence,":[372],"21":[373],"(60%)":[374],"redo":[377],"ablation,":[378],"these,":[381],"4":[382],"(11.4%)":[383],"second":[386],"one.":[387],"At":[388],"end":[390],"follow-up":[393],"(which":[394],"included":[395],"patients),":[397],"there":[398],"16":[400],"recurrences,":[401],"events":[407],"rate":[408],"74.6%.":[410],"On":[411,447],"univariate":[412,470],"logistic":[413,449],"regression":[414],"factors":[417],"associated":[419],"higher":[422],"were:":[426],"female":[427],"sex":[428],"(OR":[429,434,445],"3.7),":[430],"left":[431,437,454,489,539,559,575],"ventricular":[432],"dysfunction":[433],"2.71),":[435],"dilation":[439,456,577],"(>40":[440],"ml/m2)":[441],"assessed":[442],"CMR":[444],"9.12).":[446],"multivariate":[448],"regression,":[450],"independent":[460,547],"predictor":[461,548],"recurrence.":[463,550],"This":[464,551],"association":[465],"confirmed":[468],"Cox":[471],"analysis":[472],"Kaplan-Meier":[474],"survival":[475],"curves,":[476],"which":[477,542],"shorter":[481],"recurrence-free":[482],"dilated":[488],"atrium":[490],"compared":[491],"those":[493],"normal":[495],"dimensions":[497],"(log-rank":[498],"10.351;":[499],"p":[500],"=":[501],"0.001).":[502],"Conclusions":[503],"results":[506],"indicate":[511],"that":[512],"arrhythmia":[518],"primarily":[524],"influenced":[525],"degree":[528],"remodeling":[531],"and,":[532],"particular,":[534],"dilation,":[541],"emerges":[543],"finding":[552],"highlights":[553],"crucial":[555],"role":[556],"sections":[561],"even":[562],"predominantly":[565],"affected":[566],"right":[568],"conditions.":[570],"early":[572],"identification":[573],"through":[578],"advanced":[579],"could":[581],"allow":[583],"better":[585],"prognostic":[586],"stratification,":[587],"guide":[588],"timing":[590],"ablative":[593],"favor":[596],"strategies,":[599],"potential":[602],"improve":[604],"outcomes":[606],"quality":[609],"life":[611],"complex":[614],"patient":[615],"population.":[616]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-08-07T00:00:00"}