{"id":"https://openalex.org/W7172397699","doi":"https://doi.org/10.1158/0008-5472.33151451","title":"Supplementary Figure 3 from Armored Chimeric Antigen Receptor T-cell Therapy Targets Antigen-Heterogeneous Glioma","display_name":"Supplementary Figure 3 from Armored Chimeric Antigen Receptor T-cell Therapy Targets Antigen-Heterogeneous Glioma","publication_year":2026,"publication_date":"2026-08-04","ids":{"openalex":"https://openalex.org/W7172397699","doi":"https://doi.org/10.1158/0008-5472.33151451"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.33151451","doi":"https://doi.org/10.1158/0008-5472.33151451","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.33151451","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/0008-5472.33151451","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074578491","display_name":"Justin D. Clubb","orcid":"https://orcid.org/0000-0001-9819-6619","observed_orcids":["https://orcid.org/0000-0001-9819-6619"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Justin D. Clubb","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9819-6619","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073028791","display_name":"Ryan M. Shih","orcid":"https://orcid.org/0000-0002-3570-867X","observed_orcids":["https://orcid.org/0000-0002-3570-867X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ryan M. Shih","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3570-867X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068831937","display_name":"Torahito A. Gao","orcid":"https://orcid.org/0000-0003-4333-5305","observed_orcids":["https://orcid.org/0000-0003-4333-5305"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Torahito A. Gao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4333-5305","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055455964","display_name":"Amanda M. Shafer","orcid":"https://orcid.org/0000-0003-2931-1569","observed_orcids":["https://orcid.org/0000-0003-2931-1569","https://orcid.org/0009-0008-6959-1968"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amanda Shafer","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2931-1569","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116390883","display_name":"Shreya Vajragiri","orcid":"https://orcid.org/0009-0005-5825-7073","observed_orcids":["https://orcid.org/0009-0005-5825-7073"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shreya Vajragiri","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-5825-7073","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039096079","display_name":"Katrina Lam","orcid":"https://orcid.org/0009-0006-9537-177X","observed_orcids":["https://orcid.org/0009-0006-9537-177X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katrina Lam","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-9537-177X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079575713","display_name":"Sohan Talluri","orcid":"https://orcid.org/0000-0003-1140-1929","observed_orcids":["https://orcid.org/0000-0003-1140-1929"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sohan Talluri","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1140-1929","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5095380199","display_name":"Amber Bouren","orcid":"https://orcid.org/0009-0004-0385-3276","observed_orcids":["https://orcid.org/0009-0004-0385-3276"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amber Bouren","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0004-0385-3276","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010868067","display_name":"Christine E. Brown","orcid":"https://orcid.org/0000-0003-4915-8207","observed_orcids":["https://orcid.org/0000-0003-4915-8207"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christine E. Brown","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4915-8207","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066111159","display_name":"Pedro Ruivo","orcid":"https://orcid.org/0000-0002-5419-4790","observed_orcids":["https://orcid.org/0000-0002-5419-4790"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pedro Ruivo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5419-4790","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010449744","display_name":"Robert Michael Prins","orcid":"https://orcid.org/0000-0002-6282-6583","observed_orcids":["https://orcid.org/0000-0002-6282-6583"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert M. Prins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6282-6583","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100368795","display_name":"Han\u2010Chung Wu","orcid":"https://orcid.org/0000-0002-5185-1169","observed_orcids":["https://orcid.org/0000-0002-5185-1169"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Han-Chung Wu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5185-1169","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5078815820","display_name":"Yvonne Y. Chen","orcid":"https://orcid.org/0000-0002-5583-119X","observed_orcids":["https://orcid.org/0000-0002-5583-119X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yvonne Y. Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5583-119X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/armored-car-t-cells","display_name":"armored CAR-T cells","score":0.8820000290870667},{"id":"https://openalex.org/keywords/chimeric-antigen-receptor","display_name":"chimeric antigen receptor","score":0.8920000195503235},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.9190000295639038},{"id":"https://openalex.org/keywords/gene-delivery","display_name":"gene delivery","score":0.39500001072883606},{"id":"https://openalex.org/keywords/car-t-cell-engineering","display_name":"CAR-T cell engineering","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C3875195","wikidata":"https://www.wikidata.org/wiki/Q5099363","display_name":"Chimeric antigen receptor","level":4,"score":0.7067999839782715},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6026999950408936},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.5062999725341797},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3995000123977661},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.39469999074935913},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38429999351501465},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.3822000026702881},{"id":"https://openalex.org/C192328126","wikidata":"https://www.wikidata.org/wiki/Q4514647","display_name":"Schematic","level":2,"score":0.3472999930381775},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.34689998626708984},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3257000148296356},{"id":"https://openalex.org/C2908856526","wikidata":"https://www.wikidata.org/wiki/Q16252627","display_name":"Antibody therapy","level":4,"score":0.3089999854564667},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3037000000476837},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.27140000462532043},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.27070000767707825},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2702000141143799},{"id":"https://openalex.org/C82210918","wikidata":"https://www.wikidata.org/wiki/Q1560099","display_name":"Oncolytic virus","level":3,"score":0.2533000111579895}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/0008-5472.33151451","doi":"https://doi.org/10.1158/0008-5472.33151451","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.33151451","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.33151451","doi":"https://doi.org/10.1158/0008-5472.33151451","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.33151451","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3000952285","https://openalex.org/W7161829133","https://openalex.org/W7172407330","https://openalex.org/W2123481965","https://openalex.org/W2431026834","https://openalex.org/W4309018039","https://openalex.org/W4407866598","https://openalex.org/W2989331432","https://openalex.org/W4309017253","https://openalex.org/W4200392576"],"abstract_inverted_index":{"Fig.":[0],"S3.":[1],"Schematics":[2],"of":[3],"multi-cistronic":[4],"armored":[5],"CAR-T":[6],"cell":[7],"constructs.":[8]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-08-05T00:00:00"}