{"id":"https://openalex.org/W7171964495","doi":"https://doi.org/10.1192/j.eurpsy.2026.12204","title":"Late-Onset Schizophrenia (\u2265 50 Years): A Retrospective Study of 30 Hospitalized Psychiatric Cases","display_name":"Late-Onset Schizophrenia (\u2265 50 Years): A Retrospective Study of 30 Hospitalized Psychiatric Cases","publication_year":2026,"publication_date":"2026-06-01","ids":{"openalex":"https://openalex.org/W7171964495","doi":"https://doi.org/10.1192/j.eurpsy.2026.12204"},"language":"en","primary_location":{"id":"doi:10.1192/j.eurpsy.2026.12204","doi":"https://doi.org/10.1192/j.eurpsy.2026.12204","is_oa":true,"landing_page_url":"https://doi.org/10.1192/j.eurpsy.2026.12204","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FAA0EF999D8B2477970181F8D0A7F501/S0924933826122044a.pdf/div-class-title-late-onset-schizophrenia-50-years-a-retrospective-study-of-30-hospitalized-psychiatric-cases-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FAA0EF999D8B2477970181F8D0A7F501/S0924933826122044a.pdf/div-class-title-late-onset-schizophrenia-50-years-a-retrospective-study-of-30-hospitalized-psychiatric-cases-div.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5144165385","display_name":"R. Rahoua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091090","display_name":"Centre Hospitalier Universitaire Mohammed VI","ror":"https://ror.org/009nscf91","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210091090"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"R. Rahoua","raw_affiliation_strings":["Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI","institution_ids":["https://openalex.org/I4210091090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144133381","display_name":"H. Zizi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091090","display_name":"Centre Hospitalier Universitaire Mohammed VI","ror":"https://ror.org/009nscf91","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210091090"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"H. Zizi","raw_affiliation_strings":["Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI","institution_ids":["https://openalex.org/I4210091090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022847810","display_name":"Mohammed Berghalout","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091090","display_name":"Centre Hospitalier Universitaire Mohammed VI","ror":"https://ror.org/009nscf91","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210091090"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"M. Berghalout","raw_affiliation_strings":["Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI","institution_ids":["https://openalex.org/I4210091090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133934207","display_name":"Prof. I. Adali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091090","display_name":"Centre Hospitalier Universitaire Mohammed VI","ror":"https://ror.org/009nscf91","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210091090"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"I. Adali","raw_affiliation_strings":["Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI","institution_ids":["https://openalex.org/I4210091090"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5144099491","display_name":"F. Manoudi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091090","display_name":"Centre Hospitalier Universitaire Mohammed VI","ror":"https://ror.org/009nscf91","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210091090"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"F. Manoudi","raw_affiliation_strings":["Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychiatry, Ibn Nafis Hospital \u2013 University Hospital Center Mohammed VI","institution_ids":["https://openalex.org/I4210091090"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5144165385"],"corresponding_institution_ids":["https://openalex.org/I4210091090"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":{"value":3300,"currency":"USD","value_usd":3300},"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"69","issue":"S1","first_page":"S933","last_page":"S933"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13397","display_name":"Hallucinations in medical conditions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/late-onset-schizophrenia","display_name":"late-onset schizophrenia","score":1.0},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.8679999709129333},{"id":"https://openalex.org/keywords/persecutory-delusions","display_name":"persecutory delusions","score":0.800000011920929},{"id":"https://openalex.org/keywords/auditory-hallucinations","display_name":"auditory hallucinations","score":0.9990000128746033},{"id":"https://openalex.org/keywords/atypical-antipsychotics","display_name":"atypical antipsychotics","score":0.871999979019165},{"id":"https://openalex.org/keywords/risperidone","display_name":"risperidone","score":0.996999979019165},{"id":"https://openalex.org/keywords/antipsychotic-side-effects","display_name":"antipsychotic adverse effects","score":0.9850000143051147},{"id":"https://openalex.org/keywords/negative-symptoms","display_name":"negative symptoms","score":0.7490000128746033},{"id":"https://openalex.org/keywords/clinical-course","display_name":"clinical course","score":0.546999990940094},{"id":"https://openalex.org/keywords/hospitalization","display_name":"hospitalization","score":0.46000000834465027}],"concepts":[{"id":"https://openalex.org/C2780057945","wikidata":"https://www.wikidata.org/wiki/Q412443","display_name":"Risperidone","level":3,"score":0.8331999778747559},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.708899974822998},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.6574000120162964},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6179999709129333},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5440000295639038},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.5342000126838684},{"id":"https://openalex.org/C2776601460","wikidata":"https://www.wikidata.org/wiki/Q721073","display_name":"Delusional disorder","level":3,"score":0.5252000093460083},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.49869999289512634},{"id":"https://openalex.org/C2779043874","wikidata":"https://www.wikidata.org/wiki/Q189643","display_name":"Delusion","level":2,"score":0.47589999437332153},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4632999897003174},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.41260001063346863},{"id":"https://openalex.org/C2781204524","wikidata":"https://www.wikidata.org/wiki/Q2802443","display_name":"Diagnosis of schizophrenia","level":3,"score":0.3910999894142151},{"id":"https://openalex.org/C2778697850","wikidata":"https://www.wikidata.org/wiki/Q210999","display_name":"Psychiatric hospital","level":2,"score":0.3783000111579895},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.3763999938964844},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33889999985694885},{"id":"https://openalex.org/C2777767895","wikidata":"https://www.wikidata.org/wiki/Q4691924","display_name":"Age of onset","level":3,"score":0.3179999887943268},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.3070000112056732},{"id":"https://openalex.org/C2776921671","wikidata":"https://www.wikidata.org/wiki/Q758295","display_name":"Atypical antipsychotic","level":4,"score":0.2867000102996826},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.27630001306533813},{"id":"https://openalex.org/C123273963","wikidata":"https://www.wikidata.org/wiki/Q624758","display_name":"Psychopathology","level":2,"score":0.259799987077713}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1192/j.eurpsy.2026.12204","doi":"https://doi.org/10.1192/j.eurpsy.2026.12204","is_oa":true,"landing_page_url":"https://doi.org/10.1192/j.eurpsy.2026.12204","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FAA0EF999D8B2477970181F8D0A7F501/S0924933826122044a.pdf/div-class-title-late-onset-schizophrenia-50-years-a-retrospective-study-of-30-hospitalized-psychiatric-cases-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13444740","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13444740/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13444740/pdf/S0924933826122044a.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur Psychiatry","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1192/j.eurpsy.2026.12204","doi":"https://doi.org/10.1192/j.eurpsy.2026.12204","is_oa":true,"landing_page_url":"https://doi.org/10.1192/j.eurpsy.2026.12204","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FAA0EF999D8B2477970181F8D0A7F501/S0924933826122044a.pdf/div-class-title-late-onset-schizophrenia-50-years-a-retrospective-study-of-30-hospitalized-psychiatric-cases-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7171964495.pdf","grobid_xml":"https://content.openalex.org/works/W7171964495.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7095822895","https://openalex.org/W1983608699","https://openalex.org/W2411150477","https://openalex.org/W2034429604","https://openalex.org/W2401594140","https://openalex.org/W2945684701","https://openalex.org/W1996978648","https://openalex.org/W4390601537","https://openalex.org/W2385474213","https://openalex.org/W3045761267"],"abstract_inverted_index":{"Introduction":[0],"Late-onset":[1,232,274],"schizophrenia":[2,123,233],"(\u2265":[3],"50":[4],"years)":[5],"is":[6,49,84,234,255],"a":[7,39,85,120,156,204,211,243],"clinical":[8,40,55,238],"entity":[9,254],"that":[10],"remains":[11],"relatively":[12],"under-studied.":[13],"It":[14],"has":[15],"drawn":[16],"the":[17,44,69,98,129,150,171,181,267],"attention":[18],"of":[19,46,75,101,122,131,149,166,187,196,200,221,229,252,286],"many":[20],"researchers":[21],"who":[22],"have":[23],"attempted":[24],"to":[25,207,257,262,266],"clarify":[26],"its":[27,53],"definition":[28],"and":[29,57,72,94,116,136,240,261,279],"characteristics.":[30],"While":[31],"most":[32,172,182],"authors":[33],"agree":[34],"on":[35],"defining":[36],"it":[37],"as":[38],"presentation":[41],"beginning":[42],"after":[43,128],"age":[45,130,148],"40,":[47],"there":[48],"still":[50],"disagreement":[51],"regarding":[52],"specific":[54,237],"features":[56,239],"progression.(Yasuda":[58],"M":[59],"et":[60,272],"al.Late-onset":[61],"schizophrenia;":[62],"2013":[63],"Apr;":[64],"71(4):707-11)":[65],"Objectives":[66],"To":[67],"describe":[68],"clinical,":[70],"therapeutic,":[71,135],"evolutionary":[73],"characteristics":[74],"elderly":[76],"patients":[77,91,151,201],"hospitalized":[78,96],"for":[79,213],"late-onset":[80],"schizophrenia.":[81],"Methods":[82],"This":[83],"descriptive":[86],"retrospective":[87],"study":[88],"involving":[89],"30":[90],"aged":[92],"60":[93],"over,":[95],"in":[97,111,164,193,219,227],"psychiatry":[99],"department":[100],"Ibn":[102],"Nafis":[103],"Hospital":[104,107],"\u2013":[105],"University":[106],"Center":[108],"Mohammed":[109],"VI":[110],"Marrakech,":[112],"between":[113],"January":[114],"2024":[115],"July":[117],"2025,":[118],"with":[119,155,210],"diagnosis":[121],"whose":[124],"first":[125],"symptoms":[126,190],"appeared":[127],"50.":[132],"Clinical,":[133],"sociodemographic,":[134],"outcome-":[137],"related":[138],"data":[139],"were":[140,170,180,191,225],"collected":[141],"from":[142],"medical":[143],"records.":[144],"Results":[145],"The":[146,160,198],"average":[147],"was":[152,162,217],"62":[153],"years,":[154],"female":[157],"predominance":[158],"(59%).":[159],"onset":[161],"insidious":[163],"48.7%":[165],"cases.":[167,222,230],"Persecutory":[168],"delusions":[169],"frequently":[173],"reported":[174],"themes":[175],"(74.3%),":[176],"while":[177],"auditory":[178],"hallucinations":[179],"common":[183],"delusional":[184],"mechanism":[185],"(81.2%":[186],"cases).":[188],"Negative":[189],"observed":[192],"only":[194],"13%":[195],"patients.":[197],"majority":[199],"(86%)":[202],"showed":[203],"good":[205],"response":[206],"antipsychotic":[208],"treatment,":[209],"preference":[212],"atypical":[214],"antipsychotics.":[215],"Risperidone":[216],"prescribed":[218],"48.3%":[220],"Adverse":[223],"effects":[224],"noted":[226],"23.7%":[228],"Conclusions":[231],"characterized":[235],"by":[236],"often":[241],"follows":[242],"more":[244],"stable":[245],"course":[246],"than":[247],"early-onset":[248],"forms.":[249],"Better":[250],"recognition":[251],"this":[253],"essential":[256],"avoid":[258],"diagnostic":[259],"delays":[260],"tailor":[263],"therapeutic":[264],"strategies":[265],"aging":[268],"population.(Wynn":[269],"Owen":[270],"PA":[271],"al.":[273],"schizophrenia:":[275],"epidemiology,":[276],"diagnosis,":[277],"management":[278],"outcomes.":[280],"Drugs":[281],"Aging.":[282],"1999":[283],"Aug;15(2):81-9).":[284],"Disclosure":[285],"Interest":[287],"None":[288],"Declared":[289]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-08-01T00:00:00"}