{"id":"https://openalex.org/W7171287285","doi":"https://doi.org/10.1016/j.neubiorev.2026.106891","title":"Molecular and functional heterogeneity of hypothalamic preoptic neurons","display_name":"Molecular and functional heterogeneity of hypothalamic preoptic neurons","publication_year":2026,"publication_date":"2026-07-26","ids":{"openalex":"https://openalex.org/W7171287285","doi":"https://doi.org/10.1016/j.neubiorev.2026.106891","pmid":"https://pubmed.ncbi.nlm.nih.gov/42503402"},"language":"en","primary_location":{"id":"doi:10.1016/j.neubiorev.2026.106891","doi":"https://doi.org/10.1016/j.neubiorev.2026.106891","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2026.106891","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.neubiorev.2026.106891","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082859982","display_name":"Ilaria Carta","orcid":"https://orcid.org/0000-0003-1270-573X","observed_orcids":["https://orcid.org/0000-0003-1270-573X"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ilaria Carta","raw_affiliation_strings":["Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, United States","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077906120","display_name":"Tushar Arora","orcid":"https://orcid.org/0009-0005-6651-6995","observed_orcids":["https://orcid.org/0009-0005-6651-6995"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tushar Arora","raw_affiliation_strings":["Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, United States","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045006990","display_name":"Dhananjay Bambah-Mukku","orcid":"https://orcid.org/0000-0001-5822-6326","observed_orcids":["https://orcid.org/0000-0001-5822-6326"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dhananjay Bambah-Mukku","raw_affiliation_strings":["Department of Psychology, University of California San Diego, La Jolla, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of California San Diego, La Jolla, CA, United States","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017700240","display_name":"Anita E. Autry","orcid":"https://orcid.org/0000-0003-3933-1977","observed_orcids":["https://orcid.org/0000-0003-3933-1977"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Anita E. Autry","raw_affiliation_strings":["Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, United States; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, United States. Electronic address: anita.autry@einsteinmed.edu"],"raw_orcid":"https://orcid.org/0000-0003-3933-1977","affiliations":[{"raw_affiliation_string":"Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, United States; Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, United States. Electronic address: anita.autry@einsteinmed.edu","institution_ids":["https://openalex.org/I129975664"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5017700240"],"corresponding_institution_ids":["https://openalex.org/I129975664"],"apc_list":{"value":4860,"currency":"USD","value_usd":4860},"apc_paid":{"value":4860,"currency":"USD","value_usd":4860},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33484848,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"189","issue":null,"first_page":"106891","last_page":"106891"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.31369999051094055,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.31369999051094055,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.2224999964237213,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.13490000367164612,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preoptic-area","display_name":"preoptic area","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/neuronal-heterogeneity","display_name":"neuronal heterogeneity","score":0.8379999995231628},{"id":"https://openalex.org/keywords/neuronal-subpopulations","display_name":"neuronal subpopulations","score":0.9359999895095825},{"id":"https://openalex.org/keywords/homeostasis","display_name":"homeostasis","score":0.6349999904632568},{"id":"https://openalex.org/keywords/social-behavior","display_name":"social behavior","score":0.8560000061988831},{"id":"https://openalex.org/keywords/sleep-regulation","display_name":"sleep regulation","score":0.546999990940094},{"id":"https://openalex.org/keywords/thermoregulation","display_name":"thermoregulation","score":0.9399999976158142},{"id":"https://openalex.org/keywords/stress-response","display_name":"stress response","score":0.8159999847412109},{"id":"https://openalex.org/keywords/reproduction","display_name":"reproduction","score":0.6159999966621399},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6970000267028809},{"id":"https://openalex.org/keywords/hormone-regulation","display_name":"hormonal regulation","score":0.5329999923706055},{"id":"https://openalex.org/keywords/neural-circuits","display_name":"neural circuits","score":0.6190000176429749},{"id":"https://openalex.org/keywords/internal-state","display_name":"internal state","score":0.6150000095367432},{"id":"https://openalex.org/keywords/sensory-integration","display_name":"sensory integration","score":0.5699999928474426},{"id":"https://openalex.org/keywords/behavioral-selection","display_name":"behavioral selection","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.5033000111579895},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5020999908447266},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45350000262260437},{"id":"https://openalex.org/C2776451244","wikidata":"https://www.wikidata.org/wiki/Q7240592","display_name":"Preoptic area","level":3,"score":0.3700000047683716},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36399999260902405},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.3531999886035919},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3458000123500824},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3255000114440918},{"id":"https://openalex.org/C2775969318","wikidata":"https://www.wikidata.org/wiki/Q192419","display_name":"Diencephalon","level":3,"score":0.29820001125335693},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.2896000146865845}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011301","descriptor_name":"Preoptic Area","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D011301","descriptor_name":"Preoptic Area","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011301","descriptor_name":"Preoptic Area","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012919","descriptor_name":"Social Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neubiorev.2026.106891","doi":"https://doi.org/10.1016/j.neubiorev.2026.106891","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2026.106891","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},{"id":"pmid:42503402","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42503402","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience and biobehavioral reviews","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.neubiorev.2026.106891","doi":"https://doi.org/10.1016/j.neubiorev.2026.106891","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neubiorev.2026.106891","pdf_url":null,"source":{"id":"https://openalex.org/S170052170","display_name":"Neuroscience & Biobehavioral Reviews","issn_l":"0149-7634","issn":["0149-7634","1873-7528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience & Biobehavioral Reviews","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306553","display_name":"Whitehall Foundation","ror":"https://ror.org/00her7k05"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":258,"referenced_works":["https://openalex.org/W571315330","https://openalex.org/W904287714","https://openalex.org/W1484414557","https://openalex.org/W1506453366","https://openalex.org/W1649056280","https://openalex.org/W1671897850","https://openalex.org/W1886714202","https://openalex.org/W1964028898","https://openalex.org/W1964782601","https://openalex.org/W1966770839","https://openalex.org/W1968458744","https://openalex.org/W1969955122","https://openalex.org/W1971359921","https://openalex.org/W1972128036","https://openalex.org/W1972744301","https://openalex.org/W1973634912","https://openalex.org/W1974869504","https://openalex.org/W1976314265","https://openalex.org/W1976862945","https://openalex.org/W1978736815","https://openalex.org/W1980567548","https://openalex.org/W1982413155","https://openalex.org/W1982682042","https://openalex.org/W1982804068","https://openalex.org/W1984879501","https://openalex.org/W1985656087","https://openalex.org/W1986629855","https://openalex.org/W1990095603","https://openalex.org/W1990370237","https://openalex.org/W1990849117","https://openalex.org/W1991847642","https://openalex.org/W1992041715","https://openalex.org/W1992174470","https://openalex.org/W1993786759","https://openalex.org/W1998286971","https://openalex.org/W2004697801","https://openalex.org/W2007536952","https://openalex.org/W2007985990","https://openalex.org/W2010330204","https://openalex.org/W2010908828","https://openalex.org/W2011785947","https://openalex.org/W2013830277","https://openalex.org/W2014287820","https://openalex.org/W2015299003","https://openalex.org/W2017147631","https://openalex.org/W2018739526","https://openalex.org/W2020358626","https://openalex.org/W2022711144","https://openalex.org/W2024364396","https://openalex.org/W2025253585","https://openalex.org/W2025566892","https://openalex.org/W2028777780","https://openalex.org/W2032640068","https://openalex.org/W2038008568","https://openalex.org/W2038219840","https://openalex.org/W2039073460","https://openalex.org/W2039254286","https://openalex.org/W2040020955","https://openalex.org/W2041037585","https://openalex.org/W2041413194","https://openalex.org/W2042324625","https://openalex.org/W2042924718","https://openalex.org/W2043054827","https://openalex.org/W2046672795","https://openalex.org/W2048601373","https://openalex.org/W2051981831","https://openalex.org/W2055917442","https://openalex.org/W2056741515","https://openalex.org/W2058432642","https://openalex.org/W2065118621","https://openalex.org/W2065727564","https://openalex.org/W2066029501","https://openalex.org/W2067767450","https://openalex.org/W2068152455","https://openalex.org/W2069949257","https://openalex.org/W2070407705","https://openalex.org/W2071256705","https://openalex.org/W2078288264","https://openalex.org/W2079336703","https://openalex.org/W2083595422","https://openalex.org/W2085318506","https://openalex.org/W2085483223","https://openalex.org/W2087453951","https://openalex.org/W2087944653","https://openalex.org/W2089231471","https://openalex.org/W2090983810","https://openalex.org/W2091462804","https://openalex.org/W2092577147","https://openalex.org/W2093880793","https://openalex.org/W2094109313","https://openalex.org/W2095323303","https://openalex.org/W2100232545","https://openalex.org/W2101642644","https://openalex.org/W2103209071","https://openalex.org/W2106505481","https://openalex.org/W2107897069","https://openalex.org/W2111824942","https://openalex.org/W2113091115","https://openalex.org/W2113836851","https://openalex.org/W2114052187","https://openalex.org/W2115044649","https://openalex.org/W2117818413","https://openalex.org/W2119279206","https://openalex.org/W2120119174","https://openalex.org/W2121311726","https://openalex.org/W2121986949","https://openalex.org/W2129890422","https://openalex.org/W2133552377","https://openalex.org/W2133834231","https://openalex.org/W2134405522","https://openalex.org/W2137155095","https://openalex.org/W2139371826","https://openalex.org/W2141060229","https://openalex.org/W2141688632","https://openalex.org/W2142686356","https://openalex.org/W2143506157","https://openalex.org/W2144040522","https://openalex.org/W2145865543","https://openalex.org/W2147466683","https://openalex.org/W2149592559","https://openalex.org/W2151573530","https://openalex.org/W2152209894","https://openalex.org/W2153981339","https://openalex.org/W2158795213","https://openalex.org/W2160133414","https://openalex.org/W2166691127","https://openalex.org/W2167495346","https://openalex.org/W2174431287","https://openalex.org/W2203475976","https://openalex.org/W2239555274","https://openalex.org/W2271190373","https://openalex.org/W2277559114","https://openalex.org/W2293357082","https://openalex.org/W2346066638","https://openalex.org/W2407372765","https://openalex.org/W2420321916","https://openalex.org/W2465721599","https://openalex.org/W2508375110","https://openalex.org/W2520969273","https://openalex.org/W2562584872","https://openalex.org/W2569381116","https://openalex.org/W2571308267","https://openalex.org/W2581977955","https://openalex.org/W2583012620","https://openalex.org/W2602954002","https://openalex.org/W2604269555","https://openalex.org/W2605514622","https://openalex.org/W2605705881","https://openalex.org/W2607245472","https://openalex.org/W2616271045","https://openalex.org/W2626314076","https://openalex.org/W2742540197","https://openalex.org/W2744176737","https://openalex.org/W2754841759","https://openalex.org/W2756432299","https://openalex.org/W2778169119","https://openalex.org/W2781006862","https://openalex.org/W2782533187","https://openalex.org/W2783929557","https://openalex.org/W2790719087","https://openalex.org/W2791285983","https://openalex.org/W2793800590","https://openalex.org/W2796159550","https://openalex.org/W2797465087","https://openalex.org/W2799544587","https://openalex.org/W2804191277","https://openalex.org/W2804776018","https://openalex.org/W2878561547","https://openalex.org/W2889500679","https://openalex.org/W2895180682","https://openalex.org/W2896871853","https://openalex.org/W2899100267","https://openalex.org/W2899224111","https://openalex.org/W2900853462","https://openalex.org/W2904971976","https://openalex.org/W2921413914","https://openalex.org/W2921478661","https://openalex.org/W2937121116","https://openalex.org/W2944442047","https://openalex.org/W2944566833","https://openalex.org/W2947979545","https://openalex.org/W2949309859","https://openalex.org/W2961231996","https://openalex.org/W2969891108","https://openalex.org/W2974674466","https://openalex.org/W2976269181","https://openalex.org/W2989148135","https://openalex.org/W2999877258","https://openalex.org/W3008627778","https://openalex.org/W3010510189","https://openalex.org/W3011727833","https://openalex.org/W3015290785","https://openalex.org/W3015370623","https://openalex.org/W3015968258","https://openalex.org/W3034267508","https://openalex.org/W3035239080","https://openalex.org/W3040415912","https://openalex.org/W3045118514","https://openalex.org/W3047498213","https://openalex.org/W3048557181","https://openalex.org/W3081158448","https://openalex.org/W3084193054","https://openalex.org/W3090594618","https://openalex.org/W3107278778","https://openalex.org/W3111532421","https://openalex.org/W3134179477","https://openalex.org/W3134952963","https://openalex.org/W3157401921","https://openalex.org/W3158048929","https://openalex.org/W3164080991","https://openalex.org/W3164324796","https://openalex.org/W3164813931","https://openalex.org/W3186804668","https://openalex.org/W3187695507","https://openalex.org/W3193574244","https://openalex.org/W3194092591","https://openalex.org/W3211098576","https://openalex.org/W4210714907","https://openalex.org/W4210872137","https://openalex.org/W4220705209","https://openalex.org/W4226023200","https://openalex.org/W4282945568","https://openalex.org/W4286717226","https://openalex.org/W4288046971","https://openalex.org/W4288707715","https://openalex.org/W4289637660","https://openalex.org/W4292566870","https://openalex.org/W4297259467","https://openalex.org/W4306812424","https://openalex.org/W4308343127","https://openalex.org/W4310940458","https://openalex.org/W4313557898","https://openalex.org/W4324360607","https://openalex.org/W4362737472","https://openalex.org/W4367301625","https://openalex.org/W4385549504","https://openalex.org/W4386001020","https://openalex.org/W4387253649","https://openalex.org/W4387392263","https://openalex.org/W4387951756","https://openalex.org/W4389670555","https://openalex.org/W4390032226","https://openalex.org/W4399592323","https://openalex.org/W4399803241","https://openalex.org/W4399986444","https://openalex.org/W4401574109","https://openalex.org/W4401611147","https://openalex.org/W4401882275","https://openalex.org/W4403096276","https://openalex.org/W4406500412","https://openalex.org/W4407960760","https://openalex.org/W4409349488","https://openalex.org/W4410019961","https://openalex.org/W4410568054","https://openalex.org/W4412737305","https://openalex.org/W4413078937","https://openalex.org/W4415437596","https://openalex.org/W4417179970"],"related_works":["https://openalex.org/W3151347086","https://openalex.org/W4409004422","https://openalex.org/W3175362279","https://openalex.org/W4408019671","https://openalex.org/W4408217872","https://openalex.org/W2616271045","https://openalex.org/W2899100267","https://openalex.org/W2583012620","https://openalex.org/W3159813695","https://openalex.org/W2435054000"],"abstract_inverted_index":{"The":[0,29],"preoptic":[1],"area":[2],"of":[3,23,71,95,106,121,152,173,189],"the":[4,21,24,27,69,78,90,93,109,118,131,167,174],"hypothalamus":[5],"(POA)":[6],"has":[7,103],"been":[8],"long":[9],"known":[10],"for":[11,20,68,200],"its":[12,177],"involvement":[13],"in":[14,50,53,83,108],"brain":[15],"functions":[16,65,136],"that":[17],"are":[18,66,74,81],"critical":[19],"survival":[22],"individual":[25],"and":[26,41,52,62,80,86,100,115,137,144,156,170,192,195],"species.":[28],"POA":[30,79,110,132,153,175],"regulates":[31],"essentially":[32],"all":[33],"homeostatic":[34,135],"functions:":[35],"sleep,":[36],"temperature,":[37],"stress":[38],"responses,":[39],"fluid":[40],"nutrient":[42],"balance.":[43],"Additionally,":[44],"it":[45],"plays":[46],"a":[47,84,197],"prominent":[48],"role":[49],"reproduction":[51],"social":[54,138],"behaviors":[55],"including":[56],"sexual":[57],"behavior,":[58],"parenting,":[59],"affiliative":[60],"behaviors,":[61],"aggression.":[63],"These":[64],"fundamental":[67],"fitness":[70],"animal":[72],"species,":[73],"heavily":[75],"controlled":[76],"by":[77],"regulated":[82],"sex-specific":[85],"hormone-dependent":[87],"manner.":[88],"In":[89],"past":[91,145],"decade,":[92],"use":[94],"modern":[96],"genetic":[97],"approaches,":[98],"biosensors,":[99],"circuit":[101,168],"mapping,":[102],"identified":[104],"subpopulations":[105],"neurons":[107],"based":[111],"on":[112],"molecular":[113,171],"profile":[114],"connectivity.":[116],"Uncovering":[117],"functional":[119,158],"roles":[120],"these":[122,181],"diverse":[123],"neuronal":[124,154],"populations":[125],"is":[126],"key":[127,134,198],"to":[128,147],"elucidating":[129],"how":[130,166,180],"controls":[133],"behaviors.":[139],"Here,":[140],"we":[141,164],"review":[142],"new":[143],"studies":[146],"offer":[148],"an":[149,187],"updated":[150],"description":[151],"sub-divisions":[155],"their":[157],"relevance.":[159],"By":[160],"synthesizing":[161],"this":[162,184],"knowledge,":[163],"discuss":[165],"anatomy":[169],"heterogeneity":[172],"inform":[176],"function,":[178],"particularly":[179],"features":[182],"shape":[183],"region":[185],"as":[186,196],"integrator":[188],"sensory":[190],"cues":[191],"internal":[193],"state,":[194],"filter":[199],"behavioral":[201],"selection.":[202]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-07-27T00:00:00"}