{"id":"https://openalex.org/W7170192012","doi":"https://doi.org/10.1016/j.kint.2026.06.033","title":"A multicenter registry study of the CD38 antibody daratumumab for the treatment of microvascular inflammation following kidney transplantation","display_name":"A multicenter registry study of the CD38 antibody daratumumab for the treatment of microvascular inflammation following kidney transplantation","publication_year":2026,"publication_date":"2026-07-23","ids":{"openalex":"https://openalex.org/W7170192012","doi":"https://doi.org/10.1016/j.kint.2026.06.033","pmid":"https://pubmed.ncbi.nlm.nih.gov/42492852"},"language":"en","primary_location":{"id":"doi:10.1016/j.kint.2026.06.033","doi":"https://doi.org/10.1016/j.kint.2026.06.033","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.kint.2026.06.033","pdf_url":"https://www.kidney-international.org/article/S0085-2538(26)00604-6/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.kidney-international.org/article/S0085-2538(26)00604-6/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084040619","display_name":"Thomas Drasch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3129555431","display_name":"University Hospital Regensburg","ror":"https://ror.org/01226dv09","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3129555431"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Drasch","raw_affiliation_strings":["Department of Nephrology, University Hospital Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, University Hospital Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I3129555431"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065170887","display_name":"Katharina A. Mayer","orcid":"https://orcid.org/0000-0003-2495-790X","observed_orcids":["https://orcid.org/0000-0003-2495-790X"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Katharina A. Mayer","raw_affiliation_strings":["Department of Medicine III, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine III, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072421522","display_name":"Georg A. B\u00f6hmig","orcid":"https://orcid.org/0000-0002-7600-912X","observed_orcids":["https://orcid.org/0000-0002-7600-912X"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Georg A. B\u00f6hmig","raw_affiliation_strings":["Department of Medicine III, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine III, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025951294","display_name":"Aylin Akifova","orcid":"https://orcid.org/0009-0003-9227-8017","observed_orcids":["https://orcid.org/0009-0003-9227-8017"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Aylin Akifova","raw_affiliation_strings":["Department of Nephrology and Intensive Care, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0009-0003-9227-8017","affiliations":[{"raw_affiliation_string":"Department of Nephrology and Intensive Care, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091559393","display_name":"Fabian Halleck","orcid":"https://orcid.org/0000-0001-9449-2058","observed_orcids":["https://orcid.org/0000-0001-9449-2058"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Fabian Halleck","raw_affiliation_strings":["Department of Nephrology and Intensive Care, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Intensive Care, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060425510","display_name":"Klemens Budde","orcid":"https://orcid.org/0000-0002-7929-5942","observed_orcids":["https://orcid.org/0000-0002-7929-5942"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klemens Budde","raw_affiliation_strings":["Department of Nephrology and Intensive Care, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-7929-5942","affiliations":[{"raw_affiliation_string":"Department of Nephrology and Intensive Care, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024372872","display_name":"David Rohlfing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Rohlfing","raw_affiliation_strings":["Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086195155","display_name":"Christian Hinze","orcid":"https://orcid.org/0000-0003-2526-1621","observed_orcids":["https://orcid.org/0000-0003-2526-1621"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Hinze","raw_affiliation_strings":["Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022028971","display_name":"Malte Andreas Kluger","orcid":"https://orcid.org/0000-0001-8186-5679","observed_orcids":["https://orcid.org/0000-0001-8186-5679"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Malte Kluger","raw_affiliation_strings":["III. Department of Medicine and Hamburg Center for Kidney Health, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"III. Department of Medicine and Hamburg Center for Kidney Health, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004648123","display_name":"Florian Grahammer","orcid":"https://orcid.org/0000-0002-7851-754X","observed_orcids":["https://orcid.org/0000-0002-7851-754X"]},"institutions":[{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Florian Grahammer","raw_affiliation_strings":["III. Department of Medicine and Hamburg Center for Kidney Health, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"III. Department of Medicine and Hamburg Center for Kidney Health, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001780636","display_name":"Jan Kowald","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125843","display_name":"University Hospital Leipzig","ror":"https://ror.org/028hv5492","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210125843"]},{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Kowald","raw_affiliation_strings":["Division of Nephrology, Department of Endocrinology, Nephrology, and Rheumatology, University of Leipzig Medical Center, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Department of Endocrinology, Nephrology, and Rheumatology, University of Leipzig Medical Center, Leipzig, Germany","institution_ids":["https://openalex.org/I4210125843","https://openalex.org/I926574661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007624991","display_name":"Sebastian Baatz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125843","display_name":"University Hospital Leipzig","ror":"https://ror.org/028hv5492","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210125843"]},{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sebastian Baatz","raw_affiliation_strings":["Division of Nephrology, Department of Endocrinology, Nephrology, and Rheumatology, University of Leipzig Medical Center, Leipzig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nephrology, Department of Endocrinology, Nephrology, and Rheumatology, University of Leipzig Medical Center, Leipzig, Germany","institution_ids":["https://openalex.org/I4210125843","https://openalex.org/I926574661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143476991","display_name":"Stefan Reuter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22465464","display_name":"University of M\u00fcnster","ror":"https://ror.org/00pd74e08","country_code":"DE","type":"education","lineage":["https://openalex.org/I22465464"]},{"id":"https://openalex.org/I4210103666","display_name":"University Hospital M\u00fcnster","ror":"https://ror.org/01856cw59","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210103666"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Reuter","raw_affiliation_strings":["Department of Internal Medicine D, Transplant Nephrology, University of Muenster, Muenster, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine D, Transplant Nephrology, University of Muenster, Muenster, Germany","institution_ids":["https://openalex.org/I22465464","https://openalex.org/I4210103666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000905393","display_name":"Stephan Kemmner","orcid":"https://orcid.org/0000-0002-1242-4914","observed_orcids":["https://orcid.org/0000-0002-1242-4914"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stephan Kemmner","raw_affiliation_strings":["Transplant Center, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany"],"raw_orcid":"https://orcid.org/0000-0002-1242-4914","affiliations":[{"raw_affiliation_string":"Transplant Center, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075622636","display_name":"Tobias Seibt","orcid":"https://orcid.org/0009-0006-0639-8867","observed_orcids":["https://orcid.org/0009-0006-0639-8867"]},"institutions":[{"id":"https://openalex.org/I3018771216","display_name":"LMU Klinikum","ror":"https://ror.org/02jet3w32","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tobias Seibt","raw_affiliation_strings":["Transplant Center, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Transplant Center, University Hospital Munich, Ludwig-Maximilians University, Munich, Germany","institution_ids":["https://openalex.org/I3018771216","https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035680262","display_name":"Mareen Pigorsch","orcid":"https://orcid.org/0000-0001-5616-7748","observed_orcids":["https://orcid.org/0000-0001-5616-7748"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mareen Pigorsch","raw_affiliation_strings":["Institute of Biometry and Clinical Epidemiology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biometry and Clinical Epidemiology, Charit\u00e9-Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071754471","display_name":"Julia Beck","orcid":"https://orcid.org/0000-0002-4143-1363","observed_orcids":["https://orcid.org/0000-0002-4143-1363","https://orcid.org/0009-0007-8556-1075"]},"institutions":[{"id":"https://openalex.org/I4387154063","display_name":"Nieders\u00e4chsische Staats- und Universit\u00e4tsbibliothek G\u00f6ttingen","ror":"https://ror.org/05745n787","country_code":"DE","type":"archive","lineage":["https://openalex.org/I4387154063","https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julia Beck","raw_affiliation_strings":["Chronix Biomedical GmbH, G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chronix Biomedical GmbH, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4387154063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066521173","display_name":"Kirsten Bornemann-Kolatzki","orcid":"https://orcid.org/0009-0008-0440-5634","observed_orcids":["https://orcid.org/0009-0008-0440-5634"]},"institutions":[{"id":"https://openalex.org/I4387154063","display_name":"Nieders\u00e4chsische Staats- und Universit\u00e4tsbibliothek G\u00f6ttingen","ror":"https://ror.org/05745n787","country_code":"DE","type":"archive","lineage":["https://openalex.org/I4387154063","https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kirsten Bornemann-Kolatzki","raw_affiliation_strings":["Chronix Biomedical GmbH, G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chronix Biomedical GmbH, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4387154063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069783216","display_name":"Ekkehard Sch\u00fctz","orcid":"https://orcid.org/0000-0002-9639-4870","observed_orcids":["https://orcid.org/0000-0002-9639-4870"]},"institutions":[{"id":"https://openalex.org/I4405281304","display_name":"Insight Molecular Diagnostics, Inc (United States)","ror":"https://ror.org/045weg456","country_code":"US","type":"company","lineage":["https://openalex.org/I4405281304"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ekkehard Sch\u00fctz","raw_affiliation_strings":["Chronix Biomedical GmbH, G\u00f6ttingen, Germany; Insight Molecular Diagnostics, Nashville, Tennessee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chronix Biomedical GmbH, G\u00f6ttingen, Germany; Insight Molecular Diagnostics, Nashville, Tennessee, USA","institution_ids":["https://openalex.org/I4405281304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055085283","display_name":"Michael Oellerich","orcid":"https://orcid.org/0000-0002-9255-2261","observed_orcids":["https://orcid.org/0000-0002-9255-2261"]},"institutions":[{"id":"https://openalex.org/I4210116730","display_name":"Universit\u00e4tsmedizin G\u00f6ttingen","ror":"https://ror.org/021ft0n22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116730"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Oellerich","raw_affiliation_strings":["Department of Clinical Pharmacology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacology, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210116730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049091055","display_name":"Bernhard Banas","orcid":"https://orcid.org/0000-0003-2076-2195","observed_orcids":["https://orcid.org/0000-0003-2076-2195"]},"institutions":[{"id":"https://openalex.org/I3129555431","display_name":"University Hospital Regensburg","ror":"https://ror.org/01226dv09","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3129555431"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bernhard Banas","raw_affiliation_strings":["Department of Nephrology, University Hospital Regensburg, Regensburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, University Hospital Regensburg, Regensburg, Germany","institution_ids":["https://openalex.org/I3129555431"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021180492","display_name":"Daniel Zecher","orcid":"https://orcid.org/0000-0002-2123-0310","observed_orcids":["https://orcid.org/0000-0002-2123-0310"]},"institutions":[{"id":"https://openalex.org/I3129555431","display_name":"University Hospital Regensburg","ror":"https://ror.org/01226dv09","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I3129555431"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Daniel Zecher","raw_affiliation_strings":["Department of Nephrology, University Hospital Regensburg, Regensburg, Germany. Electronic address: daniel.zecher@ukr.de"],"raw_orcid":"https://orcid.org/0000-0002-2123-0310","affiliations":[{"raw_affiliation_string":"Department of Nephrology, University Hospital Regensburg, Regensburg, Germany. Electronic address: daniel.zecher@ukr.de","institution_ids":["https://openalex.org/I3129555431"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5021180492"],"corresponding_institution_ids":["https://openalex.org/I3129555431"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":19.4746,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.99419617,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"110","issue":"5","first_page":"1262","last_page":"1270"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/daratumumab","display_name":"daratumumab","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cd38","display_name":"CD38","score":0.7379999756813049},{"id":"https://openalex.org/keywords/microvascular-inflammation","display_name":"microvascular inflammation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.9959999918937683},{"id":"https://openalex.org/keywords/antibody-mediated-rejection","display_name":"antibody-mediated rejection","score":0.972000002861023},{"id":"https://openalex.org/keywords/donor-specific-antibodies","display_name":"donor-specific antibodies","score":0.8270000219345093},{"id":"https://openalex.org/keywords/egfr","display_name":"EGFR","score":0.5929999947547913},{"id":"https://openalex.org/keywords/albuminuria","display_name":"albuminuria","score":0.9850000143051147},{"id":"https://openalex.org/keywords/donor-derived-cell-free-dna","display_name":"donor-derived cell-free DNA","score":0.9589999914169312},{"id":"https://openalex.org/keywords/graft-survival","display_name":"graft survival","score":0.7960000038146973},{"id":"https://openalex.org/keywords/monoclonal-antibody-therapy","display_name":"monoclonal antibody therapy","score":0.8109999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9409999847412109},{"id":"https://openalex.org/C2781119759","wikidata":"https://www.wikidata.org/wiki/Q5222113","display_name":"Daratumumab","level":4,"score":0.8901000022888184},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.6527000069618225},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5830000042915344},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5274999737739563},{"id":"https://openalex.org/C2776174234","wikidata":"https://www.wikidata.org/wiki/Q974792","display_name":"Albuminuria","level":3,"score":0.5127999782562256},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.492000013589859},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4749000072479248},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4514000117778778},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4478999972343445},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4244000017642975},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.41999998688697815},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.4196999967098236},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.3986000120639801},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3815000057220459},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.36579999327659607},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3181000053882599},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.31450000405311584},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.3116999864578247},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.296099990606308},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.29409998655319214},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.28279998898506165},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.27309998869895935},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.27250000834465027},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.27079999446868896},{"id":"https://openalex.org/C2779561371","wikidata":"https://www.wikidata.org/wiki/Q570197","display_name":"Proteinuria","level":3,"score":0.26739999651908875}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051997","descriptor_name":"ADP-ribosyl Cyclase 1","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D051997","descriptor_name":"ADP-ribosyl Cyclase 1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D064591","descriptor_name":"Allografts","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D064591","descriptor_name":"Allografts","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D064591","descriptor_name":"Allografts","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.kint.2026.06.033","doi":"https://doi.org/10.1016/j.kint.2026.06.033","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.kint.2026.06.033","pdf_url":"https://www.kidney-international.org/article/S0085-2538(26)00604-6/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},{"id":"pmid:42492852","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42492852","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney international","raw_type":"Journal Article"},{"id":"pmh:oai:epub.uni-regensburg.de:81031","doi":null,"is_oa":true,"landing_page_url":"http://orcid.org/0000-0003-2076-2195>","pdf_url":"https://epub.uni-regensburg.de/81031/1/1-s2.0-S0085253826006046-main.pdf","source":{"id":"https://openalex.org/S4306401229","display_name":"University of Regensburg Publication Server (University of Regensburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I60668342","host_organization_name":"University of Regensburg","host_organization_lineage":["https://openalex.org/I60668342"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:publications.goettingen-research-online.de:2/179209","doi":null,"is_oa":false,"landing_page_url":"https://resolver.sub.uni-goettingen.de/purl?gro-2/179209","pdf_url":null,"source":{"id":"https://openalex.org/S4306401634","display_name":"GoeScholar  The Publication Server of the Georg-August-Universit\u00e4t G\u00f6ttingen (Georg-August-Universit\u00e4t G\u00f6ttingen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210122495","host_organization_name":"Asklepios Klinik St. Georg","host_organization_lineage":["https://openalex.org/I4210122495"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.5283/epub.81031","doi":"https://doi.org/10.5283/epub.81031","is_oa":true,"landing_page_url":"https://doi.org/10.5283/epub.81031","pdf_url":null,"source":{"id":"https://openalex.org/S4306401229","display_name":"University of Regensburg Publication Server (University of Regensburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I60668342","host_organization_name":"University of Regensburg","host_organization_lineage":["https://openalex.org/I60668342"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1016/j.kint.2026.06.033","doi":"https://doi.org/10.1016/j.kint.2026.06.033","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.kint.2026.06.033","pdf_url":"https://www.kidney-international.org/article/S0085-2538(26)00604-6/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8523600697517395,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7170192012.pdf","grobid_xml":"https://content.openalex.org/works/W7170192012.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W1968094833","https://openalex.org/W2129422323","https://openalex.org/W2131708234","https://openalex.org/W2147833661","https://openalex.org/W2408658425","https://openalex.org/W2518238226","https://openalex.org/W2763624287","https://openalex.org/W2773812249","https://openalex.org/W2830360589","https://openalex.org/W2892130773","https://openalex.org/W2944291759","https://openalex.org/W2985704054","https://openalex.org/W3014873726","https://openalex.org/W3116975117","https://openalex.org/W3156100932","https://openalex.org/W3159050830","https://openalex.org/W4200321812","https://openalex.org/W4383102080","https://openalex.org/W4383559753","https://openalex.org/W4390237000","https://openalex.org/W4394683786","https://openalex.org/W4399012950","https://openalex.org/W4399275959","https://openalex.org/W4400770203","https://openalex.org/W4401224648","https://openalex.org/W4401479606","https://openalex.org/W4401498826","https://openalex.org/W4403441617","https://openalex.org/W4403710762","https://openalex.org/W4405397797","https://openalex.org/W4409320396","https://openalex.org/W4409952312","https://openalex.org/W4410418435","https://openalex.org/W4410841652","https://openalex.org/W4416688140","https://openalex.org/W7119794908","https://openalex.org/W7133928496"],"related_works":["https://openalex.org/W7165378200","https://openalex.org/W7165393769","https://openalex.org/W7203889980","https://openalex.org/W4412459732","https://openalex.org/W7165371259","https://openalex.org/W3014873726","https://openalex.org/W4411192006","https://openalex.org/W7165376728","https://openalex.org/W4397040445","https://openalex.org/W7171155403"],"abstract_inverted_index":{"Introduction":[0],"Microvascular":[1],"inflammation":[2],"(MVI)":[3],"on":[4,46,177,193],"kidney":[5,14,49,205],"biopsy":[6],"is":[7],"associated":[8],"with":[9,89,210],"reduced":[10],"graft":[11,38,162],"survival":[12],"following":[13,123],"transplantation":[15,105],"(KT).":[16],"CD38-":[17],"targeting":[18],"regimens,":[19],"including":[20],"the":[21,141,145,175,182],"monoclonal":[22],"antibody":[23,90],"daratumumab,":[24],"have":[25],"recently":[26],"emerged":[27],"as":[28],"a":[29,118],"promising":[30],"therapeutic":[31],"strategy":[32],"to":[33,68,144,149],"counteract":[34],"MVI":[35,109,148],"and":[36,56,69,94,99,106,167,186],"stabilize":[37],"function.":[39],"Methods":[40],"Here,":[41],"we":[42],"retrospectively":[43],"collected":[44],"data":[45,198],"eGFR,":[47],"albuminuria,":[48],"allograft":[50],"pathology,":[51],"donor":[52],"specific":[53],"antibodies":[54],"(DSA)":[55],"donor-derived":[57],"cell-free":[58],"DNA":[59],"(dd-cfDNA)":[60],"levels":[61,169],"from":[62,135],"70":[63],"KT":[64,208],"patients":[65,87,96,159],"both":[66],"prior":[67,143],"after":[70,155],"initiation":[71],"of":[72,85,108,120,125,133,147,184,201],"daratumumab":[73,202],"treatment.":[74],"Safety":[75],"signals":[76],"were":[77],"also":[78],"documented.":[79],"Results":[80],"The":[81],"study":[82],"cohort":[83],"consisted":[84],"59":[86],"diagnosed":[88],"mediated":[91],"rejection":[92],"(AMR)":[93],"11":[95],"showing":[97],"DSA-":[98],"C4d-negative":[100],"MVI.":[101,126,211],"Median":[102,165],"time":[103],"between":[104],"diagnosis":[107,124,146],"was":[110,115,179],"36":[111],"months.":[112],"Daratumumab":[113],"treatment":[114,187],"initiated":[116],"at":[117],"median":[119],"1.6":[121],"months":[122],"A":[127],"mixed":[128],"linear":[129],"model":[130],"showed":[131],"stabilization":[132],"eGFR":[134],"-1.6":[136],"ml/min/1.73m":[137,152],"2":[138,153],"/month":[139,154],"in":[140,203,207],"year":[142],"+0.3":[150],"83":[151],"starting":[156],"daratumumab.":[157],"Six":[158],"lost":[160],"their":[161],"during":[163,172],"follow-up.":[164],"albuminuria":[166],"dd-cfDNA":[168],"decreased":[170],"early":[171],"treatment,":[173],"whereas":[174],"effect":[176],"DSA":[178],"heterogeneous.":[180],"Both":[181],"number":[183],"doses":[185],"duration":[188],"had":[189],"no":[190],"measurable":[191],"impact":[192],"outcome.":[194],"Conclusions":[195],"Our":[196],"preliminary":[197],"suggests":[199],"efficacy":[200],"stabilizing":[204],"function":[206],"recipients":[209]},"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-07-24T00:00:00"}