{"id":"https://openalex.org/W7170087528","doi":"https://doi.org/10.1002/mco2.70589","title":"Precision Stereotactic Body Radiotherapy for Ultra\u2010Central NSCLC: Tailored Margins Reduce Toxicity Without Compromising Tumor Control","display_name":"Precision Stereotactic Body Radiotherapy for Ultra\u2010Central NSCLC: Tailored Margins Reduce Toxicity Without Compromising Tumor Control","publication_year":2026,"publication_date":"2026-07-22","ids":{"openalex":"https://openalex.org/W7170087528","doi":"https://doi.org/10.1002/mco2.70589","pmid":"https://pubmed.ncbi.nlm.nih.gov/42488704"},"language":"en","primary_location":{"id":"doi:10.1002/mco2.70589","doi":"https://doi.org/10.1002/mco2.70589","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mco2.70589","pdf_url":null,"source":{"id":"https://openalex.org/S4210236862","display_name":"MedComm","issn_l":"2688-2663","issn":["2688-2663"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedComm","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1002/mco2.70589","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5143459948","display_name":"Di Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Di Liu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143425443","display_name":"Shuangyan Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuangyan Yang","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023168652","display_name":"Yun Chen","orcid":"https://orcid.org/0009-0002-0047-6394","observed_orcids":["https://orcid.org/0009-0002-0047-6394"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Chen","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083694907","display_name":"Ming Liu","orcid":"https://orcid.org/0000-0001-9760-2806","observed_orcids":["https://orcid.org/0000-0001-9760-2806"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ming Liu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101849455","display_name":"Ruifeng Zhao","orcid":"https://orcid.org/0009-0005-9557-5556","observed_orcids":["https://orcid.org/0009-0005-9557-5556"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruifeng Zhao","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Minren Hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Minren Hu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bin Su","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Su","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024715295","display_name":"Qiongya Wu","orcid":"https://orcid.org/0000-0002-8304-0301","observed_orcids":["https://orcid.org/0000-0002-8304-0301"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"QiongYa Wu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111705402","display_name":"Hongyu Wu","orcid":"https://orcid.org/0000-0002-8193-4926","observed_orcids":["https://orcid.org/0000-0002-8193-4926"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongyu Wu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100387609","display_name":"Hui Liu","orcid":"https://orcid.org/0000-0002-7669-9386","observed_orcids":["https://orcid.org/0000-0002-7669-9386","https://orcid.org/0000-0002-7173-1420","https://orcid.org/0000-0003-2200-0063","https://orcid.org/0009-0007-8893-5124"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Liu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100648209","display_name":"Jinming Yu","orcid":"https://orcid.org/0000-0001-5933-9912","observed_orcids":["https://orcid.org/0000-0001-5933-9912"]},"institutions":[{"id":"https://openalex.org/I4210100830","display_name":"Shandong Tumor Hospital","ror":"https://ror.org/01413r497","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100830"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinming Yu","raw_affiliation_strings":["Department of Radiation Oncology Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences  Jinan China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences  Jinan China","institution_ids":["https://openalex.org/I4210100830","https://openalex.org/I4210163399"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102832973","display_name":"Yaping Xu","orcid":"https://orcid.org/0009-0002-9109-1958","observed_orcids":["https://orcid.org/0009-0002-9109-1958"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaping Xu","raw_affiliation_strings":["Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology Shanghai Pulmonary Hospital School of Medicine Tongji University  Shanghai China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.57359054,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"8","first_page":"e70589","last_page":"e70589"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.7813000082969666,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.7813000082969666,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.21570000052452087,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stereotactic-body-radiation-therapy","display_name":"stereotactic body radiotherapy","score":0.9779999852180481},{"id":"https://openalex.org/keywords/critical-structure-sparing","display_name":"critical structure sparing","score":0.3709999918937683},{"id":"https://openalex.org/keywords/treatment-related-toxicity","display_name":"treatment toxicity","score":0.5509999990463257},{"id":"https://openalex.org/keywords/local-control","display_name":"local control","score":0.671999990940094},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.9919999837875366},{"id":"https://openalex.org/keywords/internal-target-volume","display_name":"internal target volume","score":0.7139999866485596},{"id":"https://openalex.org/keywords/t-stage","display_name":"T stage","score":0.6050000190734863},{"id":"https://openalex.org/keywords/biologically-effective-dose","display_name":"biologically effective dose","score":0.7480000257492065}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9068999886512756},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5789999961853027},{"id":"https://openalex.org/C2992393070","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Stereotactic radiotherapy","level":4,"score":0.5515000224113464},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5297999978065491},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5250999927520752},{"id":"https://openalex.org/C2780387249","wikidata":"https://www.wikidata.org/wiki/Q973234","display_name":"Radiosurgery","level":3,"score":0.5027999877929688},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.4966000020503998},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.48489999771118164},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.48030000925064087},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.426800012588501},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3880999982357025},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.36739999055862427},{"id":"https://openalex.org/C2781047374","wikidata":"https://www.wikidata.org/wiki/Q2100012","display_name":"Pulmonary toxicity","level":3,"score":0.35679998993873596},{"id":"https://openalex.org/C201645570","wikidata":"https://www.wikidata.org/wiki/Q830637","display_name":"Radiation treatment planning","level":3,"score":0.349700003862381},{"id":"https://openalex.org/C155806632","wikidata":"https://www.wikidata.org/wiki/Q5299253","display_name":"Dose fractionation","level":3,"score":0.33399999141693115},{"id":"https://openalex.org/C2776283816","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Survival rate","level":2,"score":0.3034999966621399},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3018999993801117},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.29030001163482666},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.28060001134872437},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.2644999921321869}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1002/mco2.70589","doi":"https://doi.org/10.1002/mco2.70589","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mco2.70589","pdf_url":null,"source":{"id":"https://openalex.org/S4210236862","display_name":"MedComm","issn_l":"2688-2663","issn":["2688-2663"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedComm","raw_type":"journal-article"},{"id":"pmid:42488704","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42488704","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedComm","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13390614","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13390614/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13390614/pdf/MCO2-7-e70589.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"MedComm (2020)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:cf275f1f49164d248a47c64149bbd306","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/cf275f1f49164d248a47c64149bbd306","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"MedComm, Vol 7, Iss 8, Pp n/a-n/a (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/mco2.70589","doi":"https://doi.org/10.1002/mco2.70589","is_oa":true,"landing_page_url":"https://doi.org/10.1002/mco2.70589","pdf_url":null,"source":{"id":"https://openalex.org/S4210236862","display_name":"MedComm","issn_l":"2688-2663","issn":["2688-2663"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedComm","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"No poverty","score":0.7137550711631775,"id":"https://metadata.un.org/sdg/1"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1057020180","display_name":null,"funder_award_id":"24Y12800301","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G5950735187","display_name":null,"funder_award_id":"21DZ2201900","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"}],"funders":[{"id":"https://openalex.org/F4320317014","display_name":"Bethune Charitable Foundation","ror":"https://ror.org/0430c7a41"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320329745","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W2115646671","https://openalex.org/W2134134167","https://openalex.org/W2136305525","https://openalex.org/W2159746573","https://openalex.org/W2164590869","https://openalex.org/W2309884927","https://openalex.org/W2558300230","https://openalex.org/W2885187755","https://openalex.org/W2926245852","https://openalex.org/W2981764820","https://openalex.org/W3041543177","https://openalex.org/W3049010969","https://openalex.org/W3098461746","https://openalex.org/W3143418719","https://openalex.org/W3160126603","https://openalex.org/W4281656035","https://openalex.org/W4307144647","https://openalex.org/W4379281123","https://openalex.org/W4381547499","https://openalex.org/W4382399859","https://openalex.org/W4383683073","https://openalex.org/W4384701841","https://openalex.org/W4385357787","https://openalex.org/W4388802691","https://openalex.org/W4398224000","https://openalex.org/W4402462708","https://openalex.org/W4402906185","https://openalex.org/W4402906413","https://openalex.org/W4402909585","https://openalex.org/W4403916266","https://openalex.org/W4410820347"],"related_works":[],"abstract_inverted_index":{"Stereotactic":[0],"body":[1],"radiation":[2],"therapy":[3],"(SBRT)":[4],"is":[5],"effective":[6,97],"for":[7],"early-stage":[8],"non-small":[9],"cell":[10],"lung":[11],"cancer":[12],"(NSCLC),":[13],"but":[14],"the":[15,109],"treatment":[16],"of":[17,73,87,91,106,144,151],"ultra-central":[18],"NSCLC":[19],"(UCNLC)":[20],"near":[21],"critical":[22],"structures":[23,55],"remains":[24],"challenging.":[25],"This":[26],"retrospective":[27],"study":[28],"analyzed":[29],"66":[30],"patients":[31,92],"with":[32,79,138,161],"stage":[33,176],"I-II":[34],"unresectable":[35],"UCNLC":[36,45,197],"who":[37],"underwent":[38],"SBRT":[39,77],"at":[40],"Shanghai":[41],"Pulmonary":[42],"Hospital":[43],"(2020-2023).":[44],"was":[46,114],"defined":[47],"by":[48],"planning":[49],"target":[50,67],"volumes":[51,68],"(PTVs)":[52],"abutting/overlapping":[53],"vital":[54],"(proximal":[56],"bronchial":[57],"tree,":[58],"esophagus,":[59],"heart,":[60],"great":[61],"vessels,":[62],"pulmonary":[63],"vessels)":[64],"or":[65],"internal":[66],"(ITVs)":[69],"within":[70],"1":[71],"cm":[72],"these":[74],"organs.":[75],"Tailored":[76],"plans":[78],"non-uniform":[80,184],"PTV":[81,185],"margins":[82],"were":[83,122,135,157],"used":[84],"in":[85,196],"45.5%":[86],"cases,":[88],"enabling":[89],"53.3%":[90],"to":[93],"receive":[94],"a":[95,103,183],"biologically":[96],"dose":[98],"\u2265":[99],"100":[100],"Gy.":[101],"With":[102],"median":[104,110],"follow-up":[105],"32.2":[107],"months,":[108],"progression-free":[111],"survival":[112,133],"(PFS)":[113],"42.9":[115],"months;":[116],"1-":[117,139],"and":[118,124,131,140,146,148,153,172,180],"3-year":[119,141],"PFS":[120,179],"rates":[121,143,150],"93.9%":[123],"68.8%,":[125],"respectively.":[126,155],"Median":[127],"local":[128],"control":[129],"(LC)":[130],"overall":[132],"(OS)":[134],"not":[136],"reached,":[137],"LC":[142,171],"98.5%":[145,152],"84.6%,":[147],"OS":[149],"88.7%,":[154],"Toxicities":[156],"predominantly":[158],"grade":[159,164],"1-2,":[160],"only":[162],"one":[163],"3":[165],"pneumonitis.":[166],"Larger":[167],"ITV":[168],"predicted":[169,178],"poorer":[170],"PFS,":[173],"whereas":[174],"T":[175],"independently":[177],"OS.":[181],"Therefore,":[182],"strategy":[186],"maintained":[187],"clinical":[188],"efficacy":[189],"without":[190],"compromising":[191],"safety,":[192],"supporting":[193],"its":[194],"application":[195],"management.":[198]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2026-07-23T00:00:00"}