{"id":"https://openalex.org/W7170051849","doi":"https://doi.org/10.1016/j.ando.2026.102602","title":"Decision-making in primary hyperparathyroidism in older patients: Surgical or conservative management?","display_name":"Decision-making in primary hyperparathyroidism in older patients: Surgical or conservative management?","publication_year":2026,"publication_date":"2026-07-22","ids":{"openalex":"https://openalex.org/W7170051849","doi":"https://doi.org/10.1016/j.ando.2026.102602","pmid":"https://pubmed.ncbi.nlm.nih.gov/42486298"},"language":"en","primary_location":{"id":"doi:10.1016/j.ando.2026.102602","doi":"https://doi.org/10.1016/j.ando.2026.102602","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ando.2026.102602","pdf_url":"https://www.sciencedirect.com/science/article/pii/S000342662600123X/pdf","source":{"id":"https://openalex.org/S84414767","display_name":"Annales d Endocrinologie","issn_l":"0003-4266","issn":["0003-4266","2213-3941"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales d'Endocrinologie","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S000342662600123X/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107670262","display_name":"Nathana\u00ebl Bassas Letissier","orcid":"https://orcid.org/0009-0005-7618-690X","observed_orcids":["https://orcid.org/0009-0005-7618-690X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Nathana\u00ebl Bassas Letissier","raw_affiliation_strings":["Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Geriatric Department, University Hospital of Poitiers, Poitiers, France. Electronic address: nathanael.bassas@chu-poitiers.fr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Geriatric Department, University Hospital of Poitiers, Poitiers, France. Electronic address: nathanael.bassas@chu-poitiers.fr","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I32881790","https://openalex.org/I4210111187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066582314","display_name":"\u00c9velyne Liuu","orcid":"https://orcid.org/0000-0003-2758-5064","observed_orcids":["https://orcid.org/0000-0003-2758-5064","https://orcid.org/0000-0003-1817-2356"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Evelyne Liuu","raw_affiliation_strings":["Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Geriatric Department, University Hospital of Poitiers, Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Geriatric Department, University Hospital of Poitiers, Poitiers, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I32881790","https://openalex.org/I4210111187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042114542","display_name":"Gianluca Donatini","orcid":"https://orcid.org/0000-0002-6031-9115","observed_orcids":["https://orcid.org/0000-0002-6031-9115"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Gianluca Donatini","raw_affiliation_strings":["Inserm U1313-IRMETIST, General and Endocrine Surgery Department, University Hospital of Poitiers, Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U1313-IRMETIST, General and Endocrine Surgery Department, University Hospital of Poitiers, Poitiers, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210111187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076465066","display_name":"A. Miot","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aur\u00e9lie Miot","raw_affiliation_strings":["Department of Endocrinology, Diabetology & Nutrition, University Hospital of Poitiers, Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology & Nutrition, University Hospital of Poitiers, Poitiers, France","institution_ids":["https://openalex.org/I4210111187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035042782","display_name":"Sophie Deshayes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Deshayes","raw_affiliation_strings":["Department of Endocrinology, Diabetology & Nutrition, University Hospital of Poitiers, Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Diabetology & Nutrition, University Hospital of Poitiers, Poitiers, France","institution_ids":["https://openalex.org/I4210111187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109175948","display_name":"Marc Paccalin","orcid":"https://orcid.org/0009-0008-3451-3097","observed_orcids":["https://orcid.org/0009-0008-3451-3097","https://orcid.org/0000-0002-8660-8935"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marc Paccalin","raw_affiliation_strings":["Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Geriatric Department, University Hospital of Poitiers, Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Geriatric Department, University Hospital of Poitiers, Poitiers, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I32881790","https://openalex.org/I4210111187"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072018829","display_name":"H\u00e9l\u00e9na Mosbah","orcid":"https://orcid.org/0000-0001-7360-4209","observed_orcids":["https://orcid.org/0000-0001-7360-4209"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I32881790","display_name":"Universit\u00e9 de Poitiers","ror":"https://ror.org/04xhy8q59","country_code":"FR","type":"education","lineage":["https://openalex.org/I32881790"]},{"id":"https://openalex.org/I4210111187","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210111187"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Helena Mosbah","raw_affiliation_strings":["Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Department of Endocrinology, Diabetology & Nutrition, University Hospital of Poitiers, Poitiers, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, Clinical Investigation Centre, CIC 1402 University of Poitiers, Poitiers, France; Department of Endocrinology, Diabetology & Nutrition, University Hospital of Poitiers, Poitiers, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I32881790","https://openalex.org/I4210111187"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5107670262"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I32881790","https://openalex.org/I4210111187"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":{"value":3390,"currency":"USD","value_usd":3390},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38290145,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"87","issue":"6","first_page":"102602","last_page":"102602"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.7231000065803528,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.7231000065803528,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.2621999979019165,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-hyperparathyroidism","display_name":"primary hyperparathyroidism","score":1.0},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9269999861717224},{"id":"https://openalex.org/keywords/parathyroidectomy","display_name":"parathyroidectomy","score":0.9070000052452087},{"id":"https://openalex.org/keywords/conservative-treatment","display_name":"conservative treatment","score":0.9229999780654907},{"id":"https://openalex.org/keywords/frailty","display_name":"frailty","score":0.722000002861023},{"id":"https://openalex.org/keywords/pre-frailty","display_name":"pre-frailty","score":0.9150000214576721},{"id":"https://openalex.org/keywords/comprehensive-geriatric-assessment","display_name":"comprehensive geriatric assessment","score":0.984000027179718},{"id":"https://openalex.org/keywords/surgical-decision-making","display_name":"surgical decision-making","score":0.5849999785423279},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.8659999966621399},{"id":"https://openalex.org/keywords/individualized-care","display_name":"individualized care","score":0.5899999737739563},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C2779053571","wikidata":"https://www.wikidata.org/wiki/Q2919083","display_name":"Primary hyperparathyroidism","level":2,"score":0.8733000159263611},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8723999857902527},{"id":"https://openalex.org/C2775945674","wikidata":"https://www.wikidata.org/wiki/Q1344835","display_name":"Hyperparathyroidism","level":2,"score":0.4844000041484833},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.43689998984336853},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.37529999017715454},{"id":"https://openalex.org/C2984752397","wikidata":"https://www.wikidata.org/wiki/Q3259956","display_name":"Primary care","level":2,"score":0.32510000467300415},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3244999945163727},{"id":"https://openalex.org/C2777645128","wikidata":"https://www.wikidata.org/wiki/Q7136153","display_name":"Parathyroidectomy","level":4,"score":0.2870999872684479},{"id":"https://openalex.org/C3019396726","wikidata":"https://www.wikidata.org/wiki/Q25104748","display_name":"Conservative treatment","level":2,"score":0.2870999872684479},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.27709999680519104}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ando.2026.102602","doi":"https://doi.org/10.1016/j.ando.2026.102602","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ando.2026.102602","pdf_url":"https://www.sciencedirect.com/science/article/pii/S000342662600123X/pdf","source":{"id":"https://openalex.org/S84414767","display_name":"Annales d Endocrinologie","issn_l":"0003-4266","issn":["0003-4266","2213-3941"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales d'Endocrinologie","raw_type":"journal-article"},{"id":"pmid:42486298","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42486298","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales d'endocrinologie","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05773714v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05773714","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Annales d'Endocrinologie = Annals of Endocrinology, 2026, pp.102602. &#x27E8;10.1016/j.ando.2026.102602&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.ando.2026.102602","doi":"https://doi.org/10.1016/j.ando.2026.102602","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ando.2026.102602","pdf_url":"https://www.sciencedirect.com/science/article/pii/S000342662600123X/pdf","source":{"id":"https://openalex.org/S84414767","display_name":"Annales d Endocrinologie","issn_l":"0003-4266","issn":["0003-4266","2213-3941"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annales d'Endocrinologie","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320331523","display_name":"Centre Hospitalier Universitaire de Poitiers","ror":"https://ror.org/029s6hd13"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7170051849.pdf","grobid_xml":"https://content.openalex.org/works/W7170051849.grobid-xml"},"referenced_works_count":72,"referenced_works":["https://openalex.org/W1560437014","https://openalex.org/W1984554726","https://openalex.org/W1988850211","https://openalex.org/W1990912565","https://openalex.org/W2002265699","https://openalex.org/W2006318999","https://openalex.org/W2018713883","https://openalex.org/W2040390208","https://openalex.org/W2049127413","https://openalex.org/W2064584518","https://openalex.org/W2068316317","https://openalex.org/W2092946945","https://openalex.org/W2106561198","https://openalex.org/W2118546075","https://openalex.org/W2127370358","https://openalex.org/W2128529067","https://openalex.org/W2135468807","https://openalex.org/W2144102059","https://openalex.org/W2147094012","https://openalex.org/W2147725349","https://openalex.org/W2160303411","https://openalex.org/W2163338538","https://openalex.org/W2164059021","https://openalex.org/W2164186760","https://openalex.org/W2167333057","https://openalex.org/W2171660098","https://openalex.org/W2620557862","https://openalex.org/W2724859405","https://openalex.org/W2778990341","https://openalex.org/W2799409156","https://openalex.org/W2801800363","https://openalex.org/W2804827832","https://openalex.org/W2892237371","https://openalex.org/W2977841311","https://openalex.org/W2978713192","https://openalex.org/W2998079109","https://openalex.org/W3007611798","https://openalex.org/W3012759446","https://openalex.org/W3039992069","https://openalex.org/W3075871984","https://openalex.org/W3114275853","https://openalex.org/W3119678388","https://openalex.org/W3120336848","https://openalex.org/W3126928814","https://openalex.org/W3136349883","https://openalex.org/W3181484454","https://openalex.org/W3201064129","https://openalex.org/W3205860251","https://openalex.org/W3211349717","https://openalex.org/W3216724161","https://openalex.org/W4206066694","https://openalex.org/W4211092031","https://openalex.org/W4211221406","https://openalex.org/W4280582677","https://openalex.org/W4281766696","https://openalex.org/W4289517894","https://openalex.org/W4292316624","https://openalex.org/W4292362404","https://openalex.org/W4293421387","https://openalex.org/W4308314167","https://openalex.org/W4319039382","https://openalex.org/W4362658193","https://openalex.org/W4387258852","https://openalex.org/W4388784060","https://openalex.org/W4389091789","https://openalex.org/W4396587101","https://openalex.org/W4406364850","https://openalex.org/W4406364890","https://openalex.org/W4406364922","https://openalex.org/W4406364931","https://openalex.org/W4406364967","https://openalex.org/W4406365986"],"related_works":["https://openalex.org/W1984554726","https://openalex.org/W4387258852","https://openalex.org/W3016408329","https://openalex.org/W4220858454","https://openalex.org/W2728022968","https://openalex.org/W2982159102","https://openalex.org/W4309491477","https://openalex.org/W3120336848","https://openalex.org/W2065485957","https://openalex.org/W4385563223"],"abstract_inverted_index":{"Primary":[0],"hyperparathyroidism":[1],"(PHPT)":[2],"is":[3,23,47,96],"a":[4,81,134,138],"frequent":[5],"endocrine":[6,116],"disorder,":[7],"with":[8,11,31],"prevalence":[9],"increasing":[10],"age,":[12],"affecting":[13],"approximately":[14],"1.5%":[15],"of":[16,29,101,159,182],"adults":[17],"aged":[18],"over":[19,104],"65.":[20],"While":[21],"management":[22],"well":[24],"codified":[25],"before":[26],"the":[27,49,72,99,108,160,177,189,200],"age":[28],"50,":[30],"surgery":[32,46],"being":[33],"preferred,":[34],"recommendations":[35],"for":[36,84],"older":[37,126,185],"individuals":[38],"are":[39,80,149],"less":[40],"clear.":[41],"In":[42,147],"this":[43,66],"population,":[44],"however,":[45,95],"still":[48],"only":[50],"curative":[51],"option,":[52],"and":[53,60,76,118,167,179,193],"several":[54],"studies":[55],"demonstrated":[56],"improvement":[57],"in":[58,184],"cognitive":[59],"neuropsychiatric":[61],"symptoms,":[62],"following":[63],"parathyroidectomy.":[64],"However,":[65],"indication":[67],"must":[68],"be":[69],"weighed":[70],"against":[71],"patient's":[73,109,161],"co-morbidities,":[74],"frailty":[75],"wishes.":[77],"Drug-based":[78],"alternatives":[79],"valid":[82],"option":[83],"patients":[85],"unable":[86],"or":[87],"unwilling":[88],"to":[89,97,165,198],"undergo":[90],"surgery.":[91],"The":[92,172],"fundamental":[93],"question,":[94],"evaluate":[98],"suitability":[100],"one":[102],"treatment":[103],"another,":[105],"depending":[106],"on":[107],"phenotype.":[110],"A":[111,124],"transdisciplinary":[112],"approach":[113],"involving":[114],"endocrinologists,":[115],"surgeons":[117],"geriatricians":[119],"can":[120,157],"ensure":[121],"personalized":[122],"care.":[123],"robust":[125],"patient":[127,140],"may":[128],"benefit":[129,142],"from":[130,144],"surgery,":[131,166],"just":[132],"like":[133],"younger":[135],"patient,":[136],"whereas":[137],"frail":[139],"would":[141],"more":[143],"conservative":[145],"management.":[146],"what":[148],"known":[150],"as":[151],"\"pre-frail\"":[152],"patients,":[153],"comprehensive":[154],"geriatric":[155,196],"assessment":[156],"optimize":[158],"general":[162],"condition":[163],"prior":[164],"help":[168],"anticipate":[169],"postoperative":[170],"complications.":[171],"present":[173],"article":[174],"firstly":[175],"describes":[176],"clinical":[178],"biological":[180],"specificities":[181],"PHPT":[183],"adults,":[186],"secondly":[187],"compares":[188],"therapeutic":[190,201],"strategies":[191],"available,":[192],"thirdly":[194],"identifies":[195],"markers":[197],"guide":[199],"decision.":[202]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-07-23T00:00:00"}
