{"id":"https://openalex.org/W7168290989","doi":"https://doi.org/10.1016/j.jaip.2026.07.004","title":"Anaphylaxis Clinical Care Pathway: Incorporating Intranasal Epinephrine (Adrenaline)","display_name":"Anaphylaxis Clinical Care Pathway: Incorporating Intranasal Epinephrine (Adrenaline)","publication_year":2026,"publication_date":"2026-07-14","ids":{"openalex":"https://openalex.org/W7168290989","doi":"https://doi.org/10.1016/j.jaip.2026.07.004","pmid":"https://pubmed.ncbi.nlm.nih.gov/42447993","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13729804"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaip.2026.07.004","doi":"https://doi.org/10.1016/j.jaip.2026.07.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaip.2026.07.004","pdf_url":"https://www.jaci-inpractice.org/article/S2213-2198(26)00583-0/pdf","source":{"id":"https://openalex.org/S2754868259","display_name":"The Journal of Allergy and Clinical Immunology In Practice","issn_l":"2213-2198","issn":["2213-2198","2213-2201"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Allergy and Clinical Immunology: In Practice","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.jaci-inpractice.org/article/S2213-2198(26)00583-0/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077511496","display_name":"Timothy E. Dribin","orcid":"https://orcid.org/0000-0002-7483-1750","observed_orcids":["https://orcid.org/0000-0002-7483-1750"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Timothy E. Dribin","raw_affiliation_strings":["Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: Timothy.Dribin@cchmc.org"],"raw_orcid":"https://orcid.org/0000-0002-7483-1750","affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio. Electronic address: Timothy.Dribin@cchmc.org","institution_ids":["https://openalex.org/I1285204247","https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006103168","display_name":"Brad Sobolewski","orcid":"https://orcid.org/0000-0002-7664-0245","observed_orcids":["https://orcid.org/0000-0002-7664-0245"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brad Sobolewski","raw_affiliation_strings":["Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio","institution_ids":["https://openalex.org/I1285204247","https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016460678","display_name":"Ronna L. Campbell","orcid":"https://orcid.org/0000-0001-6305-6990","observed_orcids":["https://orcid.org/0000-0001-6305-6990"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronna L. Campbell","raw_affiliation_strings":["Department of Emergency Medicine, Mayo Clinic, Rochester, Minn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Mayo Clinic, Rochester, Minn","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101479548","display_name":"Paul Turner","orcid":"https://orcid.org/0000-0001-9862-5161","observed_orcids":["https://orcid.org/0000-0001-9862-5161"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul J. Turner","raw_affiliation_strings":["National Heart & Lung Institute, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Heart & Lung Institute, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072512653","display_name":"Lene H. Garvey","orcid":"https://orcid.org/0000-0002-7777-4501","observed_orcids":["https://orcid.org/0000-0002-7777-4501"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Lene H. Garvey","raw_affiliation_strings":["Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital-Herlev and Gentofte, Gentofte, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital-Herlev and Gentofte, Gentofte, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2802567020","https://openalex.org/I2802582725"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025095503","display_name":"Jasmeet Soar","orcid":"https://orcid.org/0000-0001-5970-6073","observed_orcids":["https://orcid.org/0000-0001-5970-6073"]},"institutions":[{"id":"https://openalex.org/I2801253297","display_name":"Southmead Hospital","ror":"https://ror.org/05d576879","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801253297","https://openalex.org/I4405276282"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jasmeet Soar","raw_affiliation_strings":["Southmead Hospital, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Southmead Hospital, Bristol, United Kingdom","institution_ids":["https://openalex.org/I2801253297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031674948","display_name":"Julie Wang","orcid":"https://orcid.org/0000-0002-8113-9092","observed_orcids":["https://orcid.org/0000-0002-8113-9092"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie Wang","raw_affiliation_strings":["Elliot and Roslyn Jaffe Food Allergy Institute, Kravis Children's Hospital, New York, NY; Serena and John Liew Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Elliot and Roslyn Jaffe Food Allergy Institute, Kravis Children's Hospital, New York, NY; Serena and John Liew Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110814637","display_name":"Marcus S Shaker","orcid":"https://orcid.org/0009-0009-1800-2577","observed_orcids":["https://orcid.org/0009-0009-1800-2577"]},"institutions":[{"id":"https://openalex.org/I1289422878","display_name":"Dartmouth\u2013Hitchcock Medical Center","ror":"https://ror.org/00d1dhh09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I107672454","https://openalex.org/I1289422878","https://openalex.org/I4390039337"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcus S. Shaker","raw_affiliation_strings":["Section of Allergy and Clinical Immunology, Dartmouth Hitchcock Medical Center, Lebanon, NH; Departments of Medicine and of Pediatrics, Dartmouth Geisel School of Medicine, Hanover, NH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Allergy and Clinical Immunology, Dartmouth Hitchcock Medical Center, Lebanon, NH; Departments of Medicine and of Pediatrics, Dartmouth Geisel School of Medicine, Hanover, NH","institution_ids":["https://openalex.org/I1289422878"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083900520","display_name":"Adam Tobias Fox","orcid":"https://orcid.org/0000-0002-3533-9798","observed_orcids":["https://orcid.org/0000-0002-3533-9798"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210144851","display_name":"Evelina London Children's Healthcare","ror":"https://ror.org/058pgtg13","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200166805","https://openalex.org/I4210144851"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Adam T. Fox","raw_affiliation_strings":["Department of Paediatric Allergy, Evelina London Children's Hospital & King's College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Allergy, Evelina London Children's Hospital & King's College, London, United Kingdom","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I4210144851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012199105","display_name":"Sarayna S. McGuire","orcid":"https://orcid.org/0000-0002-9086-1968","observed_orcids":["https://orcid.org/0000-0002-9086-1968"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarayna S. McGuire","raw_affiliation_strings":["Department of Emergency Medicine, Mayo Clinic, Rochester, Minn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Mayo Clinic, Rochester, Minn","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048277564","display_name":"Kenneth A. Michelson","orcid":"https://orcid.org/0000-0003-1763-7262","observed_orcids":["https://orcid.org/0000-0003-1763-7262"]},"institutions":[{"id":"https://openalex.org/I1294278766","display_name":"Lurie Children's Hospital","ror":"https://ror.org/03a6zw892","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294278766"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth A. Michelson","raw_affiliation_strings":["Division of Emergency Medicine, Ann & Robert Lurie Children's Hospital, Chicago, Ill"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Ann & Robert Lurie Children's Hospital, Chicago, Ill","institution_ids":["https://openalex.org/I1294278766"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001430191","display_name":"David Schnadower","orcid":"https://orcid.org/0000-0001-7379-7012","observed_orcids":["https://orcid.org/0000-0001-7379-7012"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Schnadower","raw_affiliation_strings":["Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio","institution_ids":["https://openalex.org/I1285204247","https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065281895","display_name":"Graham C. Roberts","orcid":"https://orcid.org/0000-0003-2252-1248","observed_orcids":["https://orcid.org/0000-0003-2252-1248"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I4210118229","display_name":"NIHR Southampton Biomedical Research Centre","ror":"https://ror.org/01qqpzg67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802965805","https://openalex.org/I4210118229","https://openalex.org/I43439940"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Graham Roberts","raw_affiliation_strings":["Faculty of Medicine, University of Southampton, David Hide Asthma and Allergy Centre, Southampton, United Kingdom; St Mary's Hospital, Isle of Wight, United Kingdom; NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Southampton, David Hide Asthma and Allergy Centre, Southampton, United Kingdom; St Mary's Hospital, Isle of Wight, United Kingdom; NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I4210118229","https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137752530","display_name":"Waleed Alqurashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]},{"id":"https://openalex.org/I2799330578","display_name":"Children's Hospital of Eastern Ontario","ror":"https://ror.org/05nsbhw27","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799330578"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Waleed Alqurashi","raw_affiliation_strings":["Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; Departments of Pediatrics and Emergency Medicine, Faculty of Medicine, University of Ottawa, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; Departments of Pediatrics and Emergency Medicine, Faculty of Medicine, University of Ottawa, Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada","institution_ids":["https://openalex.org/I153718931","https://openalex.org/I2799330578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077764333","display_name":"Moshe Ben\u2010Shoshan","orcid":"https://orcid.org/0000-0001-9083-1518","observed_orcids":["https://orcid.org/0000-0001-9083-1518"]},"institutions":[{"id":"https://openalex.org/I2799950917","display_name":"Montreal Children's Hospital","ror":"https://ror.org/04wc5jk96","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799950917"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Moshe Ben-Shoshan","raw_affiliation_strings":["Division of Allergy, Immunology, and Dermatology, Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy, Immunology, and Dermatology, Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada","institution_ids":["https://openalex.org/I2799950917","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043565807","display_name":"David C. Brousseau","orcid":"https://orcid.org/0000-0001-7995-6504","observed_orcids":["https://orcid.org/0000-0001-7995-6504"]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David C. Brousseau","raw_affiliation_strings":["Department of Pediatrics, Nemours Children's Health, Wilmington, Del; Sidney Kimmel Medical College at Thomas Jefferson University, Wilmington, Del"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Nemours Children's Health, Wilmington, Del; Sidney Kimmel Medical College at Thomas Jefferson University, Wilmington, Del","institution_ids":["https://openalex.org/I149251103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123451276","display_name":"Dianne E. Campbell","orcid":"https://orcid.org/0000-0002-0907-6963","observed_orcids":["https://orcid.org/0000-0002-0907-6963"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dianne E. Campbell","raw_affiliation_strings":["The University of Sydney Medical School, the University of Sydney, Sydney, New South Wales, Australia; National Allergy Centre of Excellence (NACE), Parkville, Victoria, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Sydney Medical School, the University of Sydney, Sydney, New South Wales, Australia; National Allergy Centre of Excellence (NACE), Parkville, Victoria, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084298635","display_name":"Andrew T. Clark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802466933","display_name":"Cambridge University Hospitals NHS Foundation Trust","ror":"https://ror.org/04v54gj93","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802466933"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew T. Clark","raw_affiliation_strings":["Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I2802466933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074756493","display_name":"A. Deschildre","orcid":"https://orcid.org/0000-0003-2006-7221","observed_orcids":["https://orcid.org/0000-0003-2006-7221","https://orcid.org/0009-0003-6902-3868"]},"institutions":[{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I3018718406","display_name":"Centre Hospitalier Universitaire de Lille","ror":"https://ror.org/02ppyfa04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406"]},{"id":"https://openalex.org/I4210104040","display_name":"H\u00f4pital Jeanne de Flandre","ror":"https://ror.org/01e8kn913","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406","https://openalex.org/I4210104040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Antoine Deschildre","raw_affiliation_strings":["Univ. Lille, CHU de Lille, Lille, France; Service de Pneumologie et d'Allergologie P\u00e9diatrique, H\u00f4pital Jeanne de Flandre, CHU de Lille, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. Lille, CHU de Lille, Lille, France; Service de Pneumologie et d'Allergologie P\u00e9diatrique, H\u00f4pital Jeanne de Flandre, CHU de Lille, Lille, France","institution_ids":["https://openalex.org/I2279609970","https://openalex.org/I3018718406","https://openalex.org/I4210104040"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005851563","display_name":"Katie Frith","orcid":"https://orcid.org/0000-0002-7258-1348","observed_orcids":["https://orcid.org/0000-0002-7258-1348"]},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210125633","display_name":"Sydney Children's Hospital","ror":"https://ror.org/02tj04e91","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210125633","https://openalex.org/I4210149013"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Katie Frith","raw_affiliation_strings":["Department of Immunology, Sydney Children's Hospital, Randwick, New South Wales, Australia; School of Clinical Medicine, University of NSW, Sydney, New South Wales, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Sydney Children's Hospital, Randwick, New South Wales, Australia; School of Clinical Medicine, University of NSW, Sydney, New South Wales, Australia","institution_ids":["https://openalex.org/I31746571","https://openalex.org/I4210125633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016233332","display_name":"Mattia Giovannini","orcid":"https://orcid.org/0000-0001-9568-6882","observed_orcids":["https://orcid.org/0000-0001-9568-6882"]},"institutions":[{"id":"https://openalex.org/I4210113625","display_name":"Meyer Children's Hospital","ror":"https://ror.org/01n2xwm51","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210113625"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mattia Giovannini","raw_affiliation_strings":["Allergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy; Department of Health Sciences, University of Florence, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy; Department of Health Sciences, University of Florence, Florence, Italy","institution_ids":["https://openalex.org/I4210113625","https://openalex.org/I45084792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007028763","display_name":"Gideon Lack","orcid":"https://orcid.org/0000-0001-7350-4021","observed_orcids":["https://orcid.org/0000-0001-7350-4021"]},"institutions":[{"id":"https://openalex.org/I1324925910","display_name":"St Thomas' Hospital","ror":"https://ror.org/054gk2851","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1324925910","https://openalex.org/I200166805","https://openalex.org/I4210111135"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210144851","display_name":"Evelina London Children's Healthcare","ror":"https://ror.org/058pgtg13","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I200166805","https://openalex.org/I4210144851"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gideon Lack","raw_affiliation_strings":["Department of Women and Children's Health (Paediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Women and Children's Health (Paediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom","institution_ids":["https://openalex.org/I1324925910","https://openalex.org/I183935753","https://openalex.org/I4210144851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076448184","display_name":"Antonella Maria Muraro","orcid":"https://orcid.org/0000-0002-5026-5862","observed_orcids":["https://orcid.org/0000-0002-5026-5862"]},"institutions":[{"id":"https://openalex.org/I4210146744","display_name":"Azienda Ospedale - Universit\u00e0 Padova","ror":"https://ror.org/04bhk6583","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146744"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonella Muraro","raw_affiliation_strings":["Food Allergy Referral Centre, Padua University Hospital, Padua, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Food Allergy Referral Centre, Padua University Hospital, Padua, Italy","institution_ids":["https://openalex.org/I4210146744"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070704943","display_name":"Mark I. Neuman","orcid":"https://orcid.org/0000-0002-1988-3304","observed_orcids":["https://orcid.org/0000-0002-1988-3304","https://orcid.org/0009-0003-5043-7550"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark I. Neuman","raw_affiliation_strings":["Division of Emergency Medicine, Boston Children's Hospital, Boston, Mass"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Emergency Medicine, Boston Children's Hospital, Boston, Mass","institution_ids":["https://openalex.org/I1288882113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050542314","display_name":"Nandinee Patel","orcid":"https://orcid.org/0000-0002-4997-9411","observed_orcids":["https://orcid.org/0000-0002-4997-9411"]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nandinee Patel","raw_affiliation_strings":["National Heart & Lung Institute, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Heart & Lung Institute, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091121121","display_name":"Guillaume Pouessel","orcid":"https://orcid.org/0000-0003-4118-6385","observed_orcids":["https://orcid.org/0000-0003-4118-6385"]},"institutions":[{"id":"https://openalex.org/I2279609970","display_name":"Universit\u00e9 de Lille","ror":"https://ror.org/02kzqn938","country_code":"FR","type":"education","lineage":["https://openalex.org/I2279609970"]},{"id":"https://openalex.org/I3018718406","display_name":"Centre Hospitalier Universitaire de Lille","ror":"https://ror.org/02ppyfa04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406"]},{"id":"https://openalex.org/I4210087002","display_name":"Centre Hospitalier de Roubaix","ror":"https://ror.org/0014n6t23","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210087002"]},{"id":"https://openalex.org/I4210104040","display_name":"H\u00f4pital Jeanne de Flandre","ror":"https://ror.org/01e8kn913","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3018718406","https://openalex.org/I4210104040"]},{"id":"https://openalex.org/I4387155751","display_name":"Evaluation des technologies de sant\u00e9 et des pratiques m\u00e9dicales","ror":"https://ror.org/01qygwc68","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2279609970","https://openalex.org/I3018718406","https://openalex.org/I4387155751"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Guillaume Pouessel","raw_affiliation_strings":["Department of Pediatrics, Children's Hospital, CH Roubaix, Roubaix, France; Pediatric Pulmonology and Allergy Department, P\u00f4le Enfant, H\u00f4pital Jeanne de Flandre, CHU Lille, Lille, France; University of Lille, ULR 2694: METRICS, Lille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Children's Hospital, CH Roubaix, Roubaix, France; Pediatric Pulmonology and Allergy Department, P\u00f4le Enfant, H\u00f4pital Jeanne de Flandre, CHU Lille, Lille, France; University of Lille, ULR 2694: METRICS, Lille, France","institution_ids":["https://openalex.org/I2279609970","https://openalex.org/I3018718406","https://openalex.org/I4210087002","https://openalex.org/I4210104040","https://openalex.org/I4387155751"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039039906","display_name":"Kristina Rueter","orcid":"https://orcid.org/0009-0006-7043-7699","observed_orcids":["https://orcid.org/0009-0006-7043-7699"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2800419323","display_name":"Princess Margaret Hospital for Children","ror":"https://ror.org/04ec98z42","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800419323","https://openalex.org/I2800882159","https://openalex.org/I4387155440"]},{"id":"https://openalex.org/I4387155440","display_name":"Perth Children's Hospital","ror":"https://ror.org/015zx6n37","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4387155440"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Kristina Rueter","raw_affiliation_strings":["Departments of Immunology and Emergency Medicine, Perth Children's Hospital, Perth, Western Australia, Australia; UWA Medical School, Institute for Perioperative Excellence, The University of Western Australia, Perth, Western Australia, Australia; UWA Medical School, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Immunology and Emergency Medicine, Perth Children's Hospital, Perth, Western Australia, Australia; UWA Medical School, Institute for Perioperative Excellence, The University of Western Australia, Perth, Western Australia, Australia; UWA Medical School, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia, Australia","institution_ids":["https://openalex.org/I177877127","https://openalex.org/I2800419323","https://openalex.org/I4387155440"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112060072","display_name":"Nicholas Sargant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801868026","display_name":"Bristol Royal Hospital for Children","ror":"https://ror.org/01qgecw57","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801868026","https://openalex.org/I4405276282"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicholas Sargant","raw_affiliation_strings":["Departments of Paediatric Allergy and Children's Emergency Medicine, Bristol Royal Hospital for Children, Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Paediatric Allergy and Children's Emergency Medicine, Bristol Royal Hospital for Children, Bristol, United Kingdom","institution_ids":["https://openalex.org/I2801868026"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5140699234","display_name":"Peter Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Peter Smith","raw_affiliation_strings":["Clinical Medicine, Griffith University, Southport, Queensland, Australia; Queensland Allergy Services Private Practice, Southport, Queensland, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medicine, Griffith University, Southport, Queensland, Australia; Queensland Allergy Services Private Practice, Southport, Queensland, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048737172","display_name":"Susan Waserman","orcid":"https://orcid.org/0000-0002-2136-5995","observed_orcids":["https://orcid.org/0000-0002-2136-5995"]},"institutions":[{"id":"https://openalex.org/I59293822","display_name":"St. Joseph\u2019s Healthcare Hamilton","ror":"https://ror.org/009z39p97","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I59293822"]},{"id":"https://openalex.org/I76442945","display_name":"Hamilton Health Sciences","ror":"https://ror.org/02dqdxm48","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I76442945"]},{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Susan Waserman","raw_affiliation_strings":["Division of Clinical Immunology and Allergy, Hamilton Health Sciences, St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Immunology and Allergy, Hamilton Health Sciences, St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada","institution_ids":["https://openalex.org/I59293822","https://openalex.org/I76442945","https://openalex.org/I98251732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074602745","display_name":"Gary Wong","orcid":"https://orcid.org/0000-0001-5939-812X","observed_orcids":["https://orcid.org/0000-0001-5939-812X"]},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Gary Wing-Kin Wong","raw_affiliation_strings":["Department of Paediatrics, Chinese University of Hong Kong, Hong Kong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, Chinese University of Hong Kong, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048797041","display_name":"Margitta Worm","orcid":"https://orcid.org/0000-0002-3449-1245","observed_orcids":["https://orcid.org/0000-0002-3449-1245"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Margitta Worm","raw_affiliation_strings":["Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy and Immunology, Department of Dermatology, Venerology and Allergy, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015552885","display_name":"Hugh A. Sampson","orcid":"https://orcid.org/0000-0003-1613-8875","observed_orcids":["https://orcid.org/0000-0003-1613-8875"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hugh A. Sampson","raw_affiliation_strings":["Elliot and Roslyn Jaffe Food Allergy Institute, Kravis Children's Hospital, New York, NY; Serena and John Liew Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Elliot and Roslyn Jaffe Food Allergy Institute, Kravis Children's Hospital, New York, NY; Serena and John Liew Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY","institution_ids":["https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":9,"institutions_distinct_count":45,"corresponding_author_ids":["https://openalex.org/A5077511496"],"corresponding_institution_ids":["https://openalex.org/I1285204247","https://openalex.org/I63135867"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":{"value":4000,"currency":"USD","value_usd":4000},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.26570048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"10","first_page":"2254","last_page":"2261"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anaphylaxis","display_name":"anaphylaxis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/care-pathways","display_name":"care pathways","score":0.8539999723434448},{"id":"https://openalex.org/keywords/intramuscular-epinephrine","display_name":"intramuscular epinephrine","score":0.9660000205039978},{"id":"https://openalex.org/keywords/epinephrine-infusion","display_name":"epinephrine infusion","score":0.9160000085830688},{"id":"https://openalex.org/keywords/anaphylactic-shock","display_name":"anaphylactic shock","score":0.8479999899864197},{"id":"https://openalex.org/keywords/airway-management","display_name":"airway management","score":0.8059999942779541},{"id":"https://openalex.org/keywords/allergen-elimination","display_name":"allergen removal","score":0.6349999904632568},{"id":"https://openalex.org/keywords/patient-positioning","display_name":"patient positioning","score":0.574999988079071},{"id":"https://openalex.org/keywords/positive-pressure-ventilation","display_name":"positive pressure ventilation","score":0.6949999928474426},{"id":"https://openalex.org/keywords/intravenous-fluid-resuscitation","display_name":"intravenous fluid resuscitation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/refractory-anaphylaxis","display_name":"refractory anaphylaxis","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9839000105857849},{"id":"https://openalex.org/C2775859304","wikidata":"https://www.wikidata.org/wiki/Q132621","display_name":"Epinephrine","level":2,"score":0.7129999995231628},{"id":"https://openalex.org/C2775933838","wikidata":"https://www.wikidata.org/wiki/Q168800","display_name":"Anaphylaxis","level":3,"score":0.659500002861023},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5145000219345093},{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.49070000648498535},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.49000000953674316},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4007999897003174},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3041999936103821},{"id":"https://openalex.org/C2989236134","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Patient care","level":2,"score":0.28290000557899475},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2797999978065491}],"mesh":[{"descriptor_ui":"D000281","descriptor_name":"Administration, Intranasal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000707","descriptor_name":"Anaphylaxis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000707","descriptor_name":"Anaphylaxis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D004837","descriptor_name":"Epinephrine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007273","descriptor_name":"Injections, Intramuscular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jaip.2026.07.004","doi":"https://doi.org/10.1016/j.jaip.2026.07.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaip.2026.07.004","pdf_url":"https://www.jaci-inpractice.org/article/S2213-2198(26)00583-0/pdf","source":{"id":"https://openalex.org/S2754868259","display_name":"The Journal of Allergy and Clinical Immunology In Practice","issn_l":"2213-2198","issn":["2213-2198","2213-2201"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Allergy and Clinical Immunology: In Practice","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13729804","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13729804/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13729804/pdf/nihms-2217402.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Allergy Clin Immunol Pract","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire/4813980d-c56c-432c-a593-0c68d8fe00c5","doi":null,"is_oa":true,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/4813980d-c56c-432c-a593-0c68d8fe00c5","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/review"},{"id":"pmid:42447993","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42447993","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of allergy and clinical immunology. In practice","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.jaip.2026.07.004","doi":"https://doi.org/10.1016/j.jaip.2026.07.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaip.2026.07.004","pdf_url":"https://www.jaci-inpractice.org/article/S2213-2198(26)00583-0/pdf","source":{"id":"https://openalex.org/S2754868259","display_name":"The Journal of Allergy and Clinical Immunology In Practice","issn_l":"2213-2198","issn":["2213-2198","2213-2201"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Allergy and Clinical Immunology: In Practice","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7340064226","display_name":"Improving Anaphylaxis Outcomes Through Personalized Care Strategies","funder_award_id":"1k23ai175525-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"},{"id":"https://openalex.org/F4320309075","display_name":"Food Allergy Research and Education","ror":"https://ror.org/03m2gb193"},{"id":"https://openalex.org/F4320310645","display_name":"European Respiratory Society","ror":"https://ror.org/00c8n3h65"},{"id":"https://openalex.org/F4320316412","display_name":"Aimmune Therapeutics","ror":"https://ror.org/00rrpnq66"},{"id":"https://openalex.org/F4320318316","display_name":"Celltrion","ror":"https://ror.org/05k84m754"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332175","display_name":"Health Resources and Services Administration","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"},{"id":"https://openalex.org/F4320336039","display_name":"NIHR Imperial Biomedical Research Centre","ror":"https://ror.org/01kmhx639"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7168290989.pdf","grobid_xml":"https://content.openalex.org/works/W7168290989.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1980004849","https://openalex.org/W2023036251","https://openalex.org/W2042424714","https://openalex.org/W2078546971","https://openalex.org/W2144439776","https://openalex.org/W2312722217","https://openalex.org/W2753013352","https://openalex.org/W2761854305","https://openalex.org/W2776010711","https://openalex.org/W2941409072","https://openalex.org/W2945279588","https://openalex.org/W2971224628","https://openalex.org/W2981204147","https://openalex.org/W2984998382","https://openalex.org/W2988392384","https://openalex.org/W2991634674","https://openalex.org/W3001375137","https://openalex.org/W3035053625","https://openalex.org/W3045103472","https://openalex.org/W3080913254","https://openalex.org/W3156096159","https://openalex.org/W3159075974","https://openalex.org/W3192696519","https://openalex.org/W3213759565","https://openalex.org/W4213090801","https://openalex.org/W4376113384","https://openalex.org/W4389861936","https://openalex.org/W4399654503","https://openalex.org/W4404660287","https://openalex.org/W4405663769","https://openalex.org/W4406853027","https://openalex.org/W4408667145","https://openalex.org/W4411167156","https://openalex.org/W4412106258","https://openalex.org/W4416569338","https://openalex.org/W4417289413","https://openalex.org/W7128952326","https://openalex.org/W7134230731","https://openalex.org/W7134258553","https://openalex.org/W7140227370","https://openalex.org/W7163652033"],"related_works":["https://openalex.org/W172337497","https://openalex.org/W2883511950","https://openalex.org/W4382752715","https://openalex.org/W3016158526","https://openalex.org/W4412202400","https://openalex.org/W4247742682","https://openalex.org/W2083976531","https://openalex.org/W2615116167","https://openalex.org/W2336686930","https://openalex.org/W1527137732"],"abstract_inverted_index":{"Health":[0],"care":[1],"providers":[2],"across":[3],"settings":[4,168],"must":[5],"be":[6,94,142,176,190],"trained":[7],"to":[8,36,56,123,193,197],"manage":[9],"anaphylaxis":[10,148],"by":[11],"(1)":[12],"removing":[13],"the":[14,22,34,124,158,164,187],"offending":[15],"allergen":[16],"if":[17,28],"still":[18],"present;":[19],"(2)":[20],"positioning":[21],"patient":[23,35,188],"with":[24,39,146,182],"legs":[25,40],"elevated,":[26],"and":[27,42,62,67,81,155,186],"respiratory":[29],"distress":[30],"is":[31],"present,":[32],"allow":[33],"sit":[37],"upright":[38],"extended":[41],"elevated;":[43],"(3)":[44],"immediately":[45],"administering":[46],"epinephrine":[47,92,120,139,154,170,174],"(adrenaline)":[48],"intramuscularly":[49],"(IM)":[50],"or":[51,77,87,118,121,161],"intranasally":[52],"(IN)":[53],"every":[54,96,178],"5":[55,97,179],"15":[57],"minutes":[58,98],"for":[59,109,144],"persistent":[60,147],"anaphylaxis;":[61],"(4)":[63],"optimizing":[64],"airway,":[65],"breathing,":[66],"cardiovascular":[68],"(ABC)":[69],"resuscitation.":[70,84],"This":[71],"may":[72,115],"include":[73],"supplemental":[74],"oxygen,":[75],"noninvasive":[76],"invasive":[78],"positive-pressure":[79],"ventilation,":[80],"intravenous":[82,106,138],"fluid":[83,107],"For":[85],"life-threatening":[86],"refractory":[88],"presentations,":[89],"(5)":[90],"IM/IN":[91,153,173],"should":[93,141,175,189],"administered":[95,177],"while":[99],"addressing":[100],"ABC":[101,184],"derangements;":[102],"this":[103],"includes":[104],"aggressive":[105],"resuscitation":[108],"patients":[110,145],"in":[111],"anaphylactic":[112],"shock.":[113],"Providers":[114],"continue":[116],"IM":[117],"IN":[119],"switch":[122],"other,":[125],"as":[126],"both":[127],"routes":[128],"are":[129],"considered":[130],"equally":[131],"efficacious":[132],"based":[133],"on":[134],"pharmacokinetic":[135],"data.":[136],"An":[137],"infusion":[140],"prepared":[143],"after":[149,157],"2":[150],"doses":[151],"of":[152],"initiated":[156],"third":[159],"dose,":[160],"earlier":[162],"at":[163],"provider's":[165],"discretion.":[166],"In":[167],"without":[169],"infusions,":[171],"repeat":[172],"minutes,":[180],"along":[181],"other":[183],"interventions,":[185],"transferred":[191],"quickly":[192],"a":[194],"setting":[195],"equipped":[196],"provide":[198],"advanced":[199],"resuscitative":[200],"care.":[201]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-07-15T00:00:00"}