{"id":"https://openalex.org/W7166350745","doi":"https://doi.org/10.7759/cureus.111618","title":"Hantavirus Disease: A Comprehensive Narrative Review of Epidemiology, Pathogenesis, Diagnosis, and Treatment","display_name":"Hantavirus Disease: A Comprehensive Narrative Review of Epidemiology, Pathogenesis, Diagnosis, and Treatment","publication_year":2026,"publication_date":"2026-06-27","ids":{"openalex":"https://openalex.org/W7166350745","doi":"https://doi.org/10.7759/cureus.111618","pmid":"https://pubmed.ncbi.nlm.nih.gov/42516450"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.111618","doi":"https://doi.org/10.7759/cureus.111618","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.111618","pdf_url":"https://www.cureus.com/articles/503676-hantavirus-disease-a-comprehensive-narrative-review-of-epidemiology-pathogenesis-diagnosis-and-treatment.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/503676-hantavirus-disease-a-comprehensive-narrative-review-of-epidemiology-pathogenesis-diagnosis-and-treatment.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035777260","display_name":"Anies Ahmed","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anies Ahmed","raw_affiliation_strings":["Department of Oral Medicine and Radiology, Himachal Institute of Dental Sciences, Paonta Sahib, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral Medicine and Radiology, Himachal Institute of Dental Sciences, Paonta Sahib, IND","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139464166","display_name":"Mariyam Indawala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mariyam Indawala","raw_affiliation_strings":["Department of Prosthodontics, Rutgers School of Dental Medicine, Houston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Rutgers School of Dental Medicine, Houston, USA","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138168925","display_name":"Suraiya Khan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suraiya Khan","raw_affiliation_strings":["Department of Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139499974","display_name":"Barun Kumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I887998513","display_name":"Bharati Vidyapeeth (Deemed to be University)","ror":"https://ror.org/0052mmx10","country_code":"IN","type":"education","lineage":["https://openalex.org/I887998513"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Barun Kumar","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND","institution_ids":["https://openalex.org/I887998513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026705945","display_name":"Sameer Chauhan","orcid":"https://orcid.org/0000-0002-2467-622X","observed_orcids":["https://orcid.org/0000-0002-2467-622X"]},"institutions":[{"id":"https://openalex.org/I4210111427","display_name":"KM Shah Dental College and Hospital","ror":"https://ror.org/01pfs6p94","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210111427"]},{"id":"https://openalex.org/I4210119093","display_name":"Suamandeep Vidyapeeth University","ror":"https://ror.org/02mpq1w39","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210119093"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sameer Chauhan","raw_affiliation_strings":["Department of Prosthodontics, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, IND","institution_ids":["https://openalex.org/I4210111427","https://openalex.org/I4210119093"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119366691","display_name":"Murali MR","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Murali M. R.","raw_affiliation_strings":["Department of Psychiatry, JSS Academy of Higher Education and Research, Mysuru, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, JSS Academy of Higher Education and Research, Mysuru, IND","institution_ids":["https://openalex.org/I126824641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049374275","display_name":"Vimal Satodiya","orcid":"https://orcid.org/0000-0002-2006-500X","observed_orcids":["https://orcid.org/0000-0002-2006-500X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vimal Satodiya","raw_affiliation_strings":["Department of Psychiatry, Inland Psychiatric Medical Group, Lancaster, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Inland Psychiatric Medical Group, Lancaster, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139472618","display_name":"Rahul V. C. Tiwari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387154200","display_name":"Sankalchand Patel University","ror":"https://ror.org/037y7xs42","country_code":"IN","type":"education","lineage":["https://openalex.org/I4387154200"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rahul V. C. Tiwari","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, IND","institution_ids":["https://openalex.org/I4387154200"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5139493746","display_name":"Heena Tiwari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Heena Tiwari","raw_affiliation_strings":["Department of Blood Cell, Commisionerate of Health and Family Welfare, Government of Telangana, Hyderabad, IND"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Blood Cell, Commisionerate of Health and Family Welfare, Government of Telangana, Hyderabad, IND","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.41125541,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"18","issue":"6","first_page":"e111618","last_page":"e111618"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12492","display_name":"Zoonotic diseases and public health","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hantavirus-infection","display_name":"hantavirus infection","score":0.9620000123977661},{"id":"https://openalex.org/keywords/rodent-borne-zoonoses","display_name":"rodent-borne zoonoses","score":0.8270000219345093},{"id":"https://openalex.org/keywords/epidemiology","display_name":"epidemiology","score":0.7360000014305115},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.7609999775886536},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.8970000147819519},{"id":"https://openalex.org/keywords/treatment","display_name":"treatment","score":0.8870000243186951},{"id":"https://openalex.org/keywords/prevention","display_name":"prevention","score":0.9399999976158142},{"id":"https://openalex.org/keywords/rodent-reservoirs","display_name":"rodent reservoirs","score":0.9769999980926514},{"id":"https://openalex.org/keywords/human-exposure","display_name":"human exposure","score":0.6859999895095825},{"id":"https://openalex.org/keywords/disease-surveillance","display_name":"disease surveillance","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9075999855995178},{"id":"https://openalex.org/C3020000205","wikidata":"https://www.wikidata.org/wiki/Q2412849","display_name":"Narrative review","level":2,"score":0.7903000116348267},{"id":"https://openalex.org/C199033989","wikidata":"https://www.wikidata.org/wiki/Q1318295","display_name":"Narrative","level":2,"score":0.529699981212616},{"id":"https://openalex.org/C2775992772","wikidata":"https://www.wikidata.org/wiki/Q29001073","display_name":"Hantavirus","level":3,"score":0.491100013256073},{"id":"https://openalex.org/C2910208175","wikidata":"https://www.wikidata.org/wiki/Q29001073","display_name":"Hantavirus Infection","level":4,"score":0.3763999938964844},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.36809998750686646},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.35600000619888306},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.34119999408721924},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3409999907016754},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.33399999141693115},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.32010000944137573},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.2824000120162964},{"id":"https://openalex.org/C140608501","wikidata":"https://www.wikidata.org/wiki/Q7318358","display_name":"Review article","level":2,"score":0.2809999883174896},{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.27959999442100525},{"id":"https://openalex.org/C2909376813","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus Infections","level":5,"score":0.2535000145435333},{"id":"https://openalex.org/C160284661","wikidata":"https://www.wikidata.org/wiki/Q1555235","display_name":"Life review","level":3,"score":0.25130000710487366}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.111618","doi":"https://doi.org/10.7759/cureus.111618","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.111618","pdf_url":"https://www.cureus.com/articles/503676-hantavirus-disease-a-comprehensive-narrative-review-of-epidemiology-pathogenesis-diagnosis-and-treatment.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:42516450","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42516450","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13404921","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13404921/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13404921/pdf/cureus-0018-00000111618.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.111618","doi":"https://doi.org/10.7759/cureus.111618","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.111618","pdf_url":"https://www.cureus.com/articles/503676-hantavirus-disease-a-comprehensive-narrative-review-of-epidemiology-pathogenesis-diagnosis-and-treatment.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8056568503379822}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7166350745.pdf","grobid_xml":"https://content.openalex.org/works/W7166350745.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W153649742","https://openalex.org/W1964740697","https://openalex.org/W1964776939","https://openalex.org/W1973052078","https://openalex.org/W2014586445","https://openalex.org/W2032564975","https://openalex.org/W2035778384","https://openalex.org/W2051597633","https://openalex.org/W2071396814","https://openalex.org/W2073262010","https://openalex.org/W2081212401","https://openalex.org/W2093727433","https://openalex.org/W2094905665","https://openalex.org/W2099325304","https://openalex.org/W2118588423","https://openalex.org/W2128230863","https://openalex.org/W2147968234","https://openalex.org/W2156242168","https://openalex.org/W2167422966","https://openalex.org/W2167942532","https://openalex.org/W2169552340","https://openalex.org/W2317338049","https://openalex.org/W2916004120","https://openalex.org/W2969406159","https://openalex.org/W2996815891","https://openalex.org/W3003165035","https://openalex.org/W3009705500","https://openalex.org/W3047054214","https://openalex.org/W3097480285","https://openalex.org/W3099422781","https://openalex.org/W3154063485","https://openalex.org/W3209144952","https://openalex.org/W4220871616","https://openalex.org/W4221116864","https://openalex.org/W4303184366","https://openalex.org/W4321373545","https://openalex.org/W4385665285","https://openalex.org/W4390034513","https://openalex.org/W4410215656","https://openalex.org/W4414608484"],"related_works":[],"abstract_inverted_index":{"Hantavirus":[0],"infection":[1,162],"is":[2,14],"a":[3,17],"rodent-borne":[4],"zoonotic":[5],"disease":[6,13,119,126,186],"of":[7,20,30,58,76,100,125],"considerable":[8],"public":[9,166],"health":[10,35,167],"importance.":[11],"The":[12],"associated":[15],"with":[16],"wide":[18],"spectrum":[19],"clinical":[21,52,85,128],"manifestations":[22],"and":[23,36,56,78,89,93,114,121,134,156,178,188],"continues":[24,148],"to":[25,95,149],"attract":[26],"increasing":[27],"attention":[28],"because":[29],"its":[31,37],"impact":[32],"on":[33],"human":[34,115],"evolving":[38],"epidemiological":[39],"patterns.":[40],"This":[41,103],"narrative":[42,104],"review":[43,105],"summarizes":[44],"current":[45],"knowledge":[46],"regarding":[47],"the":[48,101,107],"epidemiology,":[49],"virology,":[50],"pathogenesis,":[51,127],"features,":[53],"diagnosis,":[54,175],"management,":[55],"prevention":[57],"hantavirus":[59,161],"infection.":[60],"A":[61],"comprehensive":[62],"literature":[63],"search":[64],"was":[65],"conducted":[66],"using":[67],"major":[68],"electronic":[69],"databases,":[70],"including":[71],"PubMed/MEDLINE,":[72],"Scopus,":[73],"Embase,":[74],"Web":[75],"Science,":[77],"Google":[79],"Scholar.":[80],"Relevant":[81],"peer-reviewed":[82],"articles,":[83],"reviews,":[84],"studies,":[86],"surveillance":[87],"reports,":[88],"guidelines":[90],"were":[91],"evaluated":[92],"synthesized":[94],"provide":[96],"an":[97,164],"updated":[98],"overview":[99],"subject.":[102],"discusses":[106],"interactions":[108],"among":[109],"environmental":[110],"factors,":[111],"rodent":[112],"reservoirs,":[113],"exposure":[116],"that":[117],"influence":[118],"occurrence":[120],"transmission.":[122],"Key":[123],"aspects":[124],"presentation,":[129],"diagnostic":[130,152],"approaches,":[131],"therapeutic":[132,154],"considerations,":[133],"preventive":[135,157,180],"measures":[136],"are":[137,182],"summarized.":[138],"Current":[139],"management":[140],"strategies":[141,181],"remain":[142],"largely":[143],"supportive,":[144],"while":[145],"ongoing":[146],"research":[147],"explore":[150],"novel":[151],"tools,":[153],"options,":[155],"interventions.":[158],"In":[159],"conclusion,":[160],"remains":[163],"important":[165],"concern.":[168],"Continued":[169],"efforts":[170],"toward":[171],"improved":[172,189],"surveillance,":[173],"timely":[174],"enhanced":[176],"research,":[177],"effective":[179],"essential":[183],"for":[184],"better":[185],"control":[187],"patient":[190],"outcomes.":[191]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-06-28T00:00:00"}