{"id":"https://openalex.org/W7166326007","doi":"https://doi.org/10.1002/pfm2.70016","title":"Resveratrol: Advance on the Most Recent Research From 2021 to 2025","display_name":"Resveratrol: Advance on the Most Recent Research From 2021 to 2025","publication_year":2026,"publication_date":"2026-06-27","ids":{"openalex":"https://openalex.org/W7166326007","doi":"https://doi.org/10.1002/pfm2.70016"},"language":"en","primary_location":{"id":"doi:10.1002/pfm2.70016","doi":"https://doi.org/10.1002/pfm2.70016","is_oa":true,"landing_page_url":"https://doi.org/10.1002/pfm2.70016","pdf_url":null,"source":{"id":"https://openalex.org/S7407055876","display_name":"Phytochemicals in Food and Medicine","issn_l":"3068-7306","issn":["3068-7306"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytochemicals in Food and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1002/pfm2.70016","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084052396","display_name":"Quanyong Wu","orcid":"https://orcid.org/0009-0008-0597-9453","observed_orcids":["https://orcid.org/0009-0008-0597-9453"]},"institutions":[{"id":"https://openalex.org/I6289922","display_name":"Universidade de Vigo","ror":"https://ror.org/05rdf8595","country_code":"ES","type":"education","lineage":["https://openalex.org/I6289922"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Quanyong Wu","raw_affiliation_strings":["Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain"],"raw_orcid":"https://orcid.org/0009-0008-0597-9453","affiliations":[{"raw_affiliation_string":"Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain","institution_ids":["https://openalex.org/I6289922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111145235","display_name":"Boya Ouyang","orcid":"https://orcid.org/0009-0000-1996-0843","observed_orcids":["https://orcid.org/0009-0000-1996-0843"]},"institutions":[{"id":"https://openalex.org/I6289922","display_name":"Universidade de Vigo","ror":"https://ror.org/05rdf8595","country_code":"ES","type":"education","lineage":["https://openalex.org/I6289922"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Boya Ouyang","raw_affiliation_strings":["Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain"],"raw_orcid":"https://orcid.org/0009-0000-1996-0843","affiliations":[{"raw_affiliation_string":"Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain","institution_ids":["https://openalex.org/I6289922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070234214","display_name":"Yi Yuan","orcid":"https://orcid.org/0000-0003-0610-4575","observed_orcids":["https://orcid.org/0000-0003-0610-4575"]},"institutions":[{"id":"https://openalex.org/I80947539","display_name":"Fuzhou University","ror":"https://ror.org/011xvna82","country_code":"CN","type":"education","lineage":["https://openalex.org/I80947539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Yuan","raw_affiliation_strings":["College of Biological Science and Engineering Fuzhou University  Fuzhou China"],"raw_orcid":"https://orcid.org/0000-0003-0610-4575","affiliations":[{"raw_affiliation_string":"College of Biological Science and Engineering Fuzhou University  Fuzhou China","institution_ids":["https://openalex.org/I80947539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058196561","display_name":"Jes\u00fas Simal\u2010G\u00e1ndara","orcid":"https://orcid.org/0000-0001-9215-9737","observed_orcids":["https://orcid.org/0000-0001-9215-9737"]},"institutions":[{"id":"https://openalex.org/I6289922","display_name":"Universidade de Vigo","ror":"https://ror.org/05rdf8595","country_code":"ES","type":"education","lineage":["https://openalex.org/I6289922"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jesus Simal\u2010Gandara","raw_affiliation_strings":["Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain","institution_ids":["https://openalex.org/I6289922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024464372","display_name":"Hui Cao","orcid":"https://orcid.org/0000-0002-0584-4734","observed_orcids":["https://orcid.org/0000-0002-0584-4734"]},"institutions":[{"id":"https://openalex.org/I6289922","display_name":"Universidade de Vigo","ror":"https://ror.org/05rdf8595","country_code":"ES","type":"education","lineage":["https://openalex.org/I6289922"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Hui Cao","raw_affiliation_strings":["Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain"],"raw_orcid":"https://orcid.org/0000-0002-0584-4734","affiliations":[{"raw_affiliation_string":"Department of Analytical Chemistry and Food Science Nutrition and Bromatology Group Instituto de Agroecolox\u00eda e Alimentaci\u00f3n (IAA) Universidade de Vigo  Vigo Spain","institution_ids":["https://openalex.org/I6289922"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5024464372"],"corresponding_institution_ids":["https://openalex.org/I6289922"],"apc_list":null,"apc_paid":null,"fwci":3.9492,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.94154611,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"1","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/resveratrol","display_name":"resveratrol","score":1.0},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.9739999771118164},{"id":"https://openalex.org/keywords/natural-sources","display_name":"natural sources","score":0.6850000023841858},{"id":"https://openalex.org/keywords/physicochemical-stability","display_name":"physicochemical stability","score":0.8700000047683716},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8420000076293945},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.902999997138977},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8149999976158142},{"id":"https://openalex.org/keywords/mitochondrial-function","display_name":"mitochondrial function","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cell-fate-regulation","display_name":"cell fate regulation","score":0.925000011920929},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9980000257492065},{"id":"https://openalex.org/keywords/multi-target-mechanism","display_name":"multi-target mechanism","score":0.6240000128746033},{"id":"https://openalex.org/keywords/drug-delivery-systems","display_name":"drug delivery systems","score":0.7870000004768372},{"id":"https://openalex.org/keywords/clinical-efficacy-and-safety","display_name":"clinical efficacy and safety","score":0.7239999771118164},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.984000027179718},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.9769999980926514},{"id":"https://openalex.org/keywords/food-and-nutrition","display_name":"food and nutrition","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C2776816829","wikidata":"https://www.wikidata.org/wiki/Q407329","display_name":"Resveratrol","level":2,"score":0.8472999930381775},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4410000145435333},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.39980000257492065},{"id":"https://openalex.org/C3020442560","wikidata":"https://www.wikidata.org/wiki/Q4971815","display_name":"Broad spectrum","level":2,"score":0.38429999351501465},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.34769999980926514},{"id":"https://openalex.org/C2991874392","wikidata":"https://www.wikidata.org/wiki/Q1124842","display_name":"Metabolic stability","level":3,"score":0.34619998931884766},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3368000090122223},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33329999446868896},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.32519999146461487},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.32429999113082886},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2946000099182129},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.29269999265670776},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2786000072956085},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.2766000032424927},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.2750999927520752},{"id":"https://openalex.org/C2987857752","wikidata":"https://www.wikidata.org/wiki/Q12147","display_name":"Human health","level":2,"score":0.27140000462532043},{"id":"https://openalex.org/C2986762682","wikidata":"https://www.wikidata.org/wiki/Q964754","display_name":"Basic research","level":2,"score":0.25690001249313354},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2542000114917755},{"id":"https://openalex.org/C3018449070","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signalling pathways","level":3,"score":0.2529999911785126}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/pfm2.70016","doi":"https://doi.org/10.1002/pfm2.70016","is_oa":true,"landing_page_url":"https://doi.org/10.1002/pfm2.70016","pdf_url":null,"source":{"id":"https://openalex.org/S7407055876","display_name":"Phytochemicals in Food and Medicine","issn_l":"3068-7306","issn":["3068-7306"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytochemicals in Food and Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/pfm2.70016","doi":"https://doi.org/10.1002/pfm2.70016","is_oa":true,"landing_page_url":"https://doi.org/10.1002/pfm2.70016","pdf_url":null,"source":{"id":"https://openalex.org/S7407055876","display_name":"Phytochemicals in Food and Medicine","issn_l":"3068-7306","issn":["3068-7306"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytochemicals in Food and Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","score":0.5509597063064575,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W2964918358","https://openalex.org/W2989648004","https://openalex.org/W3093276449","https://openalex.org/W3095952034","https://openalex.org/W3107927697","https://openalex.org/W3109970951","https://openalex.org/W3118981383","https://openalex.org/W3119253981","https://openalex.org/W3123841197","https://openalex.org/W3159190166","https://openalex.org/W3169797653","https://openalex.org/W3185728462","https://openalex.org/W3191533909","https://openalex.org/W3200750256","https://openalex.org/W3207035717","https://openalex.org/W4214555023","https://openalex.org/W4214580903","https://openalex.org/W4220913803","https://openalex.org/W4221002432","https://openalex.org/W4280593409","https://openalex.org/W4290839687","https://openalex.org/W4294307923","https://openalex.org/W4295129446","https://openalex.org/W4296046266","https://openalex.org/W4296588544","https://openalex.org/W4306154904","https://openalex.org/W4306160713","https://openalex.org/W4308150223","https://openalex.org/W4308507339","https://openalex.org/W4310177373","https://openalex.org/W4315865598","https://openalex.org/W4318682934","https://openalex.org/W4321597991","https://openalex.org/W4322617466","https://openalex.org/W4324045067","https://openalex.org/W4366747914","https://openalex.org/W4382398681","https://openalex.org/W4385278033","https://openalex.org/W4385362402","https://openalex.org/W4389143138","https://openalex.org/W4389616653","https://openalex.org/W4389885012","https://openalex.org/W4390672306","https://openalex.org/W4391404516","https://openalex.org/W4392295683","https://openalex.org/W4392923424","https://openalex.org/W4393229425","https://openalex.org/W4393932006","https://openalex.org/W4397291931","https://openalex.org/W4399694757","https://openalex.org/W4399808104","https://openalex.org/W4400942852","https://openalex.org/W4401235792","https://openalex.org/W4401380424","https://openalex.org/W4402341267","https://openalex.org/W4403240808","https://openalex.org/W4404061849","https://openalex.org/W4404321435","https://openalex.org/W4404477003","https://openalex.org/W4405172978","https://openalex.org/W4405888639","https://openalex.org/W4406150409","https://openalex.org/W4406483952","https://openalex.org/W4406624968","https://openalex.org/W4406961668","https://openalex.org/W4407548009","https://openalex.org/W4407745966","https://openalex.org/W4408151788","https://openalex.org/W4409128189","https://openalex.org/W4409658247","https://openalex.org/W4411238140","https://openalex.org/W4411361727","https://openalex.org/W4411882652","https://openalex.org/W4412424399","https://openalex.org/W4412583714","https://openalex.org/W4412739203","https://openalex.org/W4416597916","https://openalex.org/W4417105154"],"related_works":[],"abstract_inverted_index":{"ABSTRACT":[0],"Resveratrol":[1],"is":[2],"a":[3,119],"naturally":[4],"occurring":[5],"polyphenolic":[6],"compound":[7],"widely":[8],"distributed":[9],"in":[10,43,127,160,220],"diverse":[11],"plant":[12],"sources":[13],"and":[14,27,61,77,98,108,130,141,151,157,165,190,198,209,216,222],"has":[15,37],"attracted":[16],"sustained":[17],"scientific":[18],"interest":[19],"due":[20],"to":[21,51,113,137,174,205],"its":[22,47,155],"antioxidant,":[23],"anti\u2010inflammatory,":[24],"metabolic":[25,109,161],"regulatory,":[26],"anti\u2010aging":[28],"properties.":[29],"Over":[30],"the":[31,44,62,81,101,114,182,213],"past":[32],"5":[33],"years,":[34],"resveratrol":[35,71,139,219],"research":[36],"progressed":[38],"substantially,":[39],"with":[40,100],"notable":[41],"advances":[42],"identification":[45],"of":[46,57,64,83,87,91,95,118,122,154,193,218],"natural":[48,183],"sources,":[49,184],"strategies":[50],"improve":[52],"physicochemical":[53],"stability,":[54,185],"deeper":[55],"elucidation":[56],"underlying":[58],"biological":[59,186],"mechanisms,":[60],"accumulation":[63],"clinical":[65,188],"evidence.":[66],"Emerging":[67],"studies":[68,170],"indicate":[69],"that":[70],"exerts":[72],"pleiotropic":[73],"effects":[74],"through":[75,104],"multi\u2010target":[76],"multi\u2010pathway":[78],"actions,":[79],"including":[80],"modulation":[82],"oxidative":[84],"stress,":[85],"attenuation":[86],"inflammatory":[88],"responses,":[89],"preservation":[90],"mitochondrial":[92],"function,":[93],"regulation":[94],"cell":[96],"fate,":[97],"interaction":[99],"gut":[102],"microbiota":[103],"shaping":[105],"microbial":[106],"composition":[107],"activity,":[110],"thereby":[111],"contributing":[112],"prevention":[115],"or":[116],"amelioration":[117],"broad":[120],"spectrum":[121],"diseases.":[123],"Meanwhile,":[124],"recent":[125],"developments":[126],"delivery":[128],"systems":[129],"formulation":[131],"technologies":[132],"have":[133,147],"provided":[134],"encouraging":[135],"approaches":[136],"enhance":[138],"stability":[140],"systemic":[142],"exposure.":[143],"Clinical":[144],"investigations":[145],"conducted":[146],"yielded":[148],"more":[149],"cautious":[150],"nuanced":[152],"evaluations":[153],"efficacy":[156],"safety,":[158],"particularly":[159],"disorders,":[162],"cardiovascular":[163],"diseases,":[164],"neurodegenerative":[166],"conditions.":[167],"Based":[168],"on":[169,181],"published":[171],"from":[172],"2021":[173],"2025,":[175],"this":[176],"review":[177],"summarizes":[178],"current":[179],"knowledge":[180],"activities,":[187],"progress,":[189],"safety":[191],"considerations":[192],"resveratrol.":[194],"Furthermore,":[195],"existing":[196],"challenges":[197],"future":[199],"perspectives":[200],"are":[201],"critically":[202],"discussed,":[203],"aiming":[204],"provide":[206],"an":[207],"updated":[208],"comprehensive":[210],"reference":[211],"for":[212],"rational":[214],"development":[215],"application":[217],"food":[221],"nutrition":[223],"sciences.":[224]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-09-23T05:00:35.095934","created_date":"2026-06-28T00:00:00"}