{"id":"https://openalex.org/W7166324619","doi":"https://doi.org/10.1111/cea.70383","title":"Determinants of Total and Inhaled Allergen\u2010Specific Immunoglobulin E in the Middle\u2010Aged and Elderly Population","display_name":"Determinants of Total and Inhaled Allergen\u2010Specific Immunoglobulin E in the Middle\u2010Aged and Elderly Population","publication_year":2026,"publication_date":"2026-06-27","ids":{"openalex":"https://openalex.org/W7166324619","doi":"https://doi.org/10.1111/cea.70383","pmid":"https://pubmed.ncbi.nlm.nih.gov/42363805"},"language":"en","primary_location":{"id":"doi:10.1111/cea.70383","doi":"https://doi.org/10.1111/cea.70383","is_oa":true,"landing_page_url":"https://doi.org/10.1111/cea.70383","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Experimental Allergy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1111/cea.70383","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5093641712","display_name":"Meryem Al Fatly","orcid":"https://orcid.org/0009-0002-1287-7777","observed_orcids":["https://orcid.org/0009-0002-1287-7777"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M. Al Fatly","raw_affiliation_strings":["Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","Division of Endocrinology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":"https://orcid.org/0009-0002-1287-7777","affiliations":[{"raw_affiliation_string":"Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Division of Endocrinology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686","https://openalex.org/I913958620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060672277","display_name":"S. Leonard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"S. Leonard","raw_affiliation_strings":["Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","Division of Allergy & Clinical Immunology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Division of Allergy & Clinical Immunology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686","https://openalex.org/I913958620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125478306","display_name":"Paul van Daele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P.L.A. van Daele","raw_affiliation_strings":["Division of Allergy & Clinical Immunology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Allergy & Clinical Immunology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686","https://openalex.org/I913958620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136260222","display_name":"Ginger Helleman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"G. Helleman","raw_affiliation_strings":["Department of Immunology, Laboratory Medical Immunology Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Laboratory Medical Immunology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139507505","display_name":"E. Torabi\u2010Azhandeh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"E. Torabi\u2010Azhandeh","raw_affiliation_strings":["Department of Immunology, Laboratory Medical Immunology Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Laboratory Medical Immunology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076311551","display_name":"Lies Lahousse","orcid":"https://orcid.org/0000-0002-3494-4363","observed_orcids":["https://orcid.org/0000-0002-3494-4363"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE","NL"],"is_corresponding":false,"raw_author_name":"L. Lahousse","raw_affiliation_strings":["Department of Bioanalysis Ghent University  Ghent Belgium","Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioanalysis Ghent University  Ghent Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054720495","display_name":"Sharon Veenbergen","orcid":"https://orcid.org/0009-0009-9114-2998","observed_orcids":["https://orcid.org/0009-0009-9114-2998"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"S. Veenbergen","raw_affiliation_strings":["Department of Immunology, Laboratory Medical Immunology Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Laboratory Medical Immunology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5139510761","display_name":"L. Chaker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]},{"id":"https://openalex.org/I913958620","display_name":"Erasmus University Rotterdam","ror":"https://ror.org/057w15z03","country_code":"NL","type":"education","lineage":["https://openalex.org/I913958620"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"L. Chaker","raw_affiliation_strings":["Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","Division of Endocrinology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Division of Endocrinology, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands","institution_ids":["https://openalex.org/I2801952686","https://openalex.org/I913958620"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4760,"currency":"USD","value_usd":4760},"apc_paid":{"value":4760,"currency":"USD","value_usd":4760},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.50251256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"56","issue":"10","first_page":"1240","last_page":"1242"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.8866999745368958,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.8866999745368958,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.10809999704360962,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/total-serum-ige","display_name":"total IgE","score":0.8569999933242798},{"id":"https://openalex.org/keywords/specific-ige","display_name":"specific IgE","score":0.8989999890327454},{"id":"https://openalex.org/keywords/aeroallergens","display_name":"aeroallergens","score":0.8949999809265137},{"id":"https://openalex.org/keywords/middle-aged-and-older-adults","display_name":"middle-aged and older adults","score":0.7940000295639038},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.7509999871253967},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8100000023841858},{"id":"https://openalex.org/keywords/topical-corticosteroids","display_name":"topical corticosteroids","score":0.9350000023841858},{"id":"https://openalex.org/keywords/inhaled-corticosteroids","display_name":"inhaled corticosteroids","score":1.0},{"id":"https://openalex.org/keywords/seasonal-variation","display_name":"seasonal variation","score":0.7310000061988831},{"id":"https://openalex.org/keywords/age-and-sex-differences","display_name":"age and sex differences","score":0.8180000185966492}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8339999914169312},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.6711000204086304},{"id":"https://openalex.org/C2991922776","wikidata":"https://www.wikidata.org/wiki/Q210420","display_name":"Inhaled corticosteroids","level":3,"score":0.6601999998092651},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.583299994468689},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.4643999934196472},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4609000086784363},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.45879998803138733},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4512999951839447},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.4472000002861023},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.38679999113082886},{"id":"https://openalex.org/C2910900810","wikidata":"https://www.wikidata.org/wiki/Q5941165","display_name":"Respiratory Hypersensitivity","level":3,"score":0.3458999991416931},{"id":"https://openalex.org/C2776804153","wikidata":"https://www.wikidata.org/wiki/Q210420","display_name":"Corticosteroid","level":2,"score":0.3208000063896179},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3073999881744385},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.2736999988555908},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.27129998803138733},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2615000009536743}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1111/cea.70383","doi":"https://doi.org/10.1111/cea.70383","is_oa":true,"landing_page_url":"https://doi.org/10.1111/cea.70383","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Experimental Allergy","raw_type":"journal-article"},{"id":"pmid:42363805","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42363805","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology","raw_type":"Journal Article"},{"id":"pmh:oai:pure.eur.nl:openaire/35f7ef95-26da-441b-bb57-b1d65be2bb38","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/35f7ef95-26da-441b-bb57-b1d65be2bb38","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Al Fatly, M, Leonard, S, van Daele, P L A, Helleman, G, Torabi-Azhandeh, E, Lahousse, L, Veenbergen, S & Chaker, L 2026, 'Determinants of Total and Inhaled Allergen-Specific Immunoglobulin E in the Middle-Aged and Elderly Population', Clinical and Experimental Allergy. https://doi.org/10.1111/cea.70383","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pubmedcentral.nih.gov:13630501","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13630501/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13630501/pdf/CEA-56-1240.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clin Exp Allergy","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1111/cea.70383","doi":"https://doi.org/10.1111/cea.70383","is_oa":true,"landing_page_url":"https://doi.org/10.1111/cea.70383","pdf_url":null,"source":{"id":"https://openalex.org/S17239246","display_name":"Clinical & Experimental Allergy","issn_l":"0954-7894","issn":["0954-7894","1365-2222"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical & Experimental Allergy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7790337204933167}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1486068373","https://openalex.org/W2327710371","https://openalex.org/W2766195635","https://openalex.org/W2804686820","https://openalex.org/W4403289297","https://openalex.org/W7119044854"],"related_works":[],"abstract_inverted_index":{"Summary":[0],"Determinants":[1,16],"of":[2,17],"total":[3],"IgE":[4,20],"were":[5,21],"age,":[6,22],"sex,":[7,23],"smoking,":[8,24],"BMI,":[9],"topical":[10,25],"and":[11,14,26,29],"inhaled":[12,18,27],"corticosteroids":[13,28],"season.":[15,30],"antigen\u2010specific":[19]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-06-28T00:00:00"}