{"id":"https://openalex.org/W7166320262","doi":"https://doi.org/10.1016/j.coi.2026.102810","title":"Ocular sarcoidosis: from clinical signs to targeted interventions","display_name":"Ocular sarcoidosis: from clinical signs to targeted interventions","publication_year":2026,"publication_date":"2026-06-27","ids":{"openalex":"https://openalex.org/W7166320262","doi":"https://doi.org/10.1016/j.coi.2026.102810","pmid":"https://pubmed.ncbi.nlm.nih.gov/42364256"},"language":"en","primary_location":{"id":"doi:10.1016/j.coi.2026.102810","doi":"https://doi.org/10.1016/j.coi.2026.102810","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.coi.2026.102810","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.coi.2026.102810","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066895083","display_name":"Thomas El Jammal","orcid":"https://orcid.org/0000-0002-5085-8342","observed_orcids":["https://orcid.org/0000-0002-5085-8342"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210087293","display_name":"Institut de Biologie et de Chimie des Prot\u00e9ines","ror":"https://ror.org/0019x5d05","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210087293","https://openalex.org/I4210096427"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210156542","display_name":"Laboratoire de Biologie Tissulaire et d'Ing\u00e9nierie Th\u00e9rapeutique","ror":"https://ror.org/04fqvqs63","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210156542"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Thomas El Jammal","raw_affiliation_strings":["Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire de Biologie Tissulaire et Ing\u00e9nierie Th\u00e9rapeutique, UMR CNRS 5305, Institut de Biologie et de Chimie des Prot\u00e9ines, 7 passage du Vercors, Universit\u00e9 Claude Bernard Lyon 1, Lyon 69367, France. Electronic address: thomas.el-jammal@chu-lyon.fr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire de Biologie Tissulaire et Ing\u00e9nierie Th\u00e9rapeutique, UMR CNRS 5305, Institut de Biologie et de Chimie des Prot\u00e9ines, 7 passage du Vercors, Universit\u00e9 Claude Bernard Lyon 1, Lyon 69367, France. Electronic address: thomas.el-jammal@chu-lyon.fr","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I4210087293","https://openalex.org/I4210089315","https://openalex.org/I4210156542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055017832","display_name":"R. Jacquot","orcid":"https://orcid.org/0000-0002-6084-995X","observed_orcids":["https://orcid.org/0000-0002-6084-995X"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4387156042","display_name":"Research on healthcare performance","ror":"https://ror.org/02ncy5p18","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4387156042"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Robin Jacquot","raw_affiliation_strings":["Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire Research on Healthcare Performance (RESHAPE), INSERM U1290, University Claude Bernard Lyon 1, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire Research on Healthcare Performance (RESHAPE), INSERM U1290, University Claude Bernard Lyon 1, Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210089315","https://openalex.org/I4387156042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035470136","display_name":"St\u00e9phane Abramowicz","orcid":"https://orcid.org/0000-0002-4450-3211","observed_orcids":["https://orcid.org/0000-0002-4450-3211"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210106256","display_name":"University Hospital of Geneva","ror":"https://ror.org/01m1pv723","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210106256"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"St\u00e9phane Abramowicz","raw_affiliation_strings":["Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Division of Clinical Immunology and Allergy, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland; Division of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Division of Clinical Immunology and Allergy, Department of Medicine, Geneva University Hospitals, Geneva, Switzerland; Division of Ophthalmology, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229","https://openalex.org/I4210089315","https://openalex.org/I4210106256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031143082","display_name":"Laurent Kodjikian","orcid":"https://orcid.org/0000-0002-3908-6716","observed_orcids":["https://orcid.org/0000-0002-3908-6716","https://orcid.org/0000-0001-7568-269X"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210111246","display_name":"Mat\u00e9riaux Ing\u00e9nierie et Science","ror":"https://ror.org/01rnfhz46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210095849","https://openalex.org/I4210111246","https://openalex.org/I48430043"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laurent Kodjikian","raw_affiliation_strings":["Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire MATEIS, UMR-CNRS 5510, INSA, Universit\u00e9 Lyon 1, Villeurbanne 69100, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire MATEIS, UMR-CNRS 5510, INSA, Universit\u00e9 Lyon 1, Villeurbanne 69100, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I4210089315","https://openalex.org/I4210111246","https://openalex.org/I48430043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073953558","display_name":"Thibaud Mathis","orcid":"https://orcid.org/0000-0002-1418-1872","observed_orcids":["https://orcid.org/0000-0002-1418-1872"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210111246","display_name":"Mat\u00e9riaux Ing\u00e9nierie et Science","ror":"https://ror.org/01rnfhz46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210095849","https://openalex.org/I4210111246","https://openalex.org/I48430043"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Thibaud Mathis","raw_affiliation_strings":["Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire MATEIS, UMR-CNRS 5510, INSA, Universit\u00e9 Lyon 1, Villeurbanne 69100, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire MATEIS, UMR-CNRS 5510, INSA, Universit\u00e9 Lyon 1, Villeurbanne 69100, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I4210089315","https://openalex.org/I4210111246","https://openalex.org/I48430043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088552441","display_name":"Yasmine Serrar","orcid":"https://orcid.org/0000-0001-6593-4064","observed_orcids":["https://orcid.org/0000-0001-6593-4064"]},"institutions":[{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yasmine Serrar","raw_affiliation_strings":["Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France","institution_ids":["https://openalex.org/I4210089315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085953878","display_name":"Lucas S\u00e9journet","orcid":"https://orcid.org/0000-0003-4395-5918","observed_orcids":["https://orcid.org/0000-0003-4395-5918"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210111246","display_name":"Mat\u00e9riaux Ing\u00e9nierie et Science","ror":"https://ror.org/01rnfhz46","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210095849","https://openalex.org/I4210111246","https://openalex.org/I48430043"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lucas S\u00e9journet","raw_affiliation_strings":["Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire MATEIS, UMR-CNRS 5510, INSA, Universit\u00e9 Lyon 1, Villeurbanne 69100, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire MATEIS, UMR-CNRS 5510, INSA, Universit\u00e9 Lyon 1, Villeurbanne 69100, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I4210089315","https://openalex.org/I4210111246","https://openalex.org/I48430043"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053823490","display_name":"Pascal S\u00e8ve","orcid":"https://orcid.org/0000-0003-3070-3842","observed_orcids":["https://orcid.org/0000-0003-3070-3842"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210089315","display_name":"H\u00f4pital de la Croix-Rousse","ror":"https://ror.org/006evg656","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210089315","https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4387156042","display_name":"Research on healthcare performance","ror":"https://ror.org/02ncy5p18","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4387156042"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pascal S\u00e8ve","raw_affiliation_strings":["Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire Research on Healthcare Performance (RESHAPE), INSERM U1290, University Claude Bernard Lyon 1, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Department, H\u00f4pital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, Lyon 69004, France; Laboratoire Research on Healthcare Performance (RESHAPE), INSERM U1290, University Claude Bernard Lyon 1, Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I4210089315","https://openalex.org/I4387156042"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5066895083"],"corresponding_institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I4210087293","https://openalex.org/I4210089315","https://openalex.org/I4210156542"],"apc_list":{"value":4410,"currency":"USD","value_usd":4410},"apc_paid":{"value":4410,"currency":"USD","value_usd":4410},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35578712,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"101","issue":null,"first_page":"102810","last_page":"102810"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11571","display_name":"Sarcoidosis and Beryllium Toxicity Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11571","display_name":"Sarcoidosis and Beryllium Toxicity Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11909","display_name":"Histiocytic Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ocular-sarcoidosis","display_name":"ocular sarcoidosis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/sarcoid-uveitis","display_name":"sarcoid uveitis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/panuveitis","display_name":"panuveitis","score":0.8109999895095825},{"id":"https://openalex.org/keywords/non-caseating-granulomas","display_name":"non-caseating granulomas","score":0.9210000038146973},{"id":"https://openalex.org/keywords/systemic-corticosteroids","display_name":"systemic corticosteroids","score":0.8159999847412109},{"id":"https://openalex.org/keywords/steroid-sparing-therapy","display_name":"steroid-sparing therapy","score":0.9819999933242798},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9549999833106995},{"id":"https://openalex.org/keywords/tnf-alpha-inhibitors","display_name":"TNF-alpha inhibitors","score":0.9940000176429749},{"id":"https://openalex.org/keywords/il-6-receptor-inhibitor","display_name":"IL-6 receptor inhibitor","score":0.9829999804496765},{"id":"https://openalex.org/keywords/jak-inhibitors","display_name":"JAK inhibitors","score":0.984000027179718},{"id":"https://openalex.org/keywords/mtor-inhibitors","display_name":"mTOR inhibitors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.5920000076293945},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7663000226020813},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5296000242233276},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.46230000257492065},{"id":"https://openalex.org/C3018875020","wikidata":"https://www.wikidata.org/wiki/Q1441305","display_name":"Signs and symptoms","level":2,"score":0.33489999175071716},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.304500013589859},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.28679999709129333},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2822999954223633},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.24969999492168427},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2362000048160553},{"id":"https://openalex.org/C2776890885","wikidata":"https://www.wikidata.org/wiki/Q1067560","display_name":"Vital signs","level":2,"score":0.21819999814033508}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005128","descriptor_name":"Eye Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005128","descriptor_name":"Eye Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D005128","descriptor_name":"Eye Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012507","descriptor_name":"Sarcoidosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012507","descriptor_name":"Sarcoidosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012507","descriptor_name":"Sarcoidosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D012507","descriptor_name":"Sarcoidosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014605","descriptor_name":"Uveitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014605","descriptor_name":"Uveitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014605","descriptor_name":"Uveitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.coi.2026.102810","doi":"https://doi.org/10.1016/j.coi.2026.102810","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.coi.2026.102810","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},{"id":"pmid:42364256","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42364256","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in immunology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05751878v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05751878","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Current Opinion in Immunology, 2026, 101, pp.102810. ⟨10.1016/j.coi.2026.102810⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.coi.2026.102810","doi":"https://doi.org/10.1016/j.coi.2026.102810","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.coi.2026.102810","pdf_url":null,"source":{"id":"https://openalex.org/S170047187","display_name":"Current Opinion in Immunology","issn_l":"0952-7915","issn":["0952-7915","1879-0372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W1529921068","https://openalex.org/W1974205417","https://openalex.org/W1977272171","https://openalex.org/W1980453791","https://openalex.org/W2026163009","https://openalex.org/W2026792729","https://openalex.org/W2058660748","https://openalex.org/W2070945215","https://openalex.org/W2072813510","https://openalex.org/W2099430274","https://openalex.org/W2116724316","https://openalex.org/W2117666935","https://openalex.org/W2128031818","https://openalex.org/W2482104393","https://openalex.org/W2573501158","https://openalex.org/W2785012303","https://openalex.org/W2807891442","https://openalex.org/W2890801659","https://openalex.org/W2893181848","https://openalex.org/W2894090142","https://openalex.org/W2898515820","https://openalex.org/W2905741745","https://openalex.org/W2915848150","https://openalex.org/W2944591918","https://openalex.org/W2957768228","https://openalex.org/W3004709581","https://openalex.org/W3015330439","https://openalex.org/W3016804057","https://openalex.org/W3035843449","https://openalex.org/W3080322413","https://openalex.org/W3086518636","https://openalex.org/W3094335520","https://openalex.org/W3109133775","https://openalex.org/W3139118194","https://openalex.org/W3150500703","https://openalex.org/W3154116690","https://openalex.org/W3154635602","https://openalex.org/W3166756865","https://openalex.org/W3207644989","https://openalex.org/W3214460730","https://openalex.org/W3215604854","https://openalex.org/W4200017235","https://openalex.org/W4211032738","https://openalex.org/W4211096509","https://openalex.org/W4252705376","https://openalex.org/W4281563192","https://openalex.org/W4283209145","https://openalex.org/W4286699768","https://openalex.org/W4319461499","https://openalex.org/W4367598752","https://openalex.org/W4367846653","https://openalex.org/W4384923764","https://openalex.org/W4386407559","https://openalex.org/W4386817509","https://openalex.org/W4389044270","https://openalex.org/W4389301911","https://openalex.org/W4391090432","https://openalex.org/W4391722939","https://openalex.org/W4400338861","https://openalex.org/W4400698751","https://openalex.org/W4400774704","https://openalex.org/W4403155368","https://openalex.org/W4404402895","https://openalex.org/W4409148327","https://openalex.org/W4409449620","https://openalex.org/W4411090543","https://openalex.org/W4413044132","https://openalex.org/W4414673737","https://openalex.org/W4415059107","https://openalex.org/W4415760750","https://openalex.org/W4416021053","https://openalex.org/W4416167009","https://openalex.org/W4416977061"],"related_works":[],"abstract_inverted_index":{"Ocular":[0],"sarcoidosis":[1,7],"is":[2,99],"a":[3,42],"frequent":[4],"manifestation":[5],"of":[6,44,59,85,91,96,125],"and":[8,17,36,48,56,66,78,117,127,141],"may":[9,22],"occur":[10],"most":[11],"commonly":[12],"affecting":[13],"adults":[14],"between":[15],"30":[16],"60":[18],"years":[19],"old.":[20],"Uveitis":[21],"be":[23],"anterior,":[24],"intermediate,":[25,76],"posterior,":[26,77],"or":[27,72,104],"present":[28],"as":[29,110],"panuveitis,":[30],"with":[31],"marked":[32],"heterogeneity":[33],"in":[34,70,101,144],"severity":[35],"clinical":[37],"course.":[38],"Diagnosis":[39],"relies":[40],"on":[41,123],"combination":[43],"compatible":[45],"ocular":[46],"findings":[47],"systemic":[49,82,92],"investigations,":[50],"including":[51],"serum":[52],"biomarkers,":[53],"thoracic":[54],"imaging,":[55],"histological":[57],"evidence":[58],"noncaseating":[60],"granulomas":[61],"while":[62],"carefully":[63],"excluding":[64],"infectious":[65],"neoplastic":[67],"mimickers,":[68],"particularly":[69],"atypical":[71],"corticosteroid-resistant":[73],"cases.":[74],"Bilateral,":[75],"panuveitis":[79],"often":[80],"require":[81],"corticosteroids.":[83],"Because":[84],"the":[86],"unfavorable":[87],"long-term":[88],"safety":[89],"profile":[90],"corticosteroids,":[93],"early":[94],"introduction":[95],"steroid-sparing":[97],"therapy":[98],"recommended":[100],"chronic,":[102],"severe,":[103],"recurrent":[105],"disease.":[106],"Emerging":[107],"therapies":[108],"such":[109],"interleukin-6":[111],"receptor":[112],"antagonists,":[113],"Janus":[114],"kinase":[115],"inhibitors,":[116],"mTOR":[118],"inhibitors":[119,129],"represent":[120],"promising":[121],"options":[122],"top":[124],"methotrexate":[126],"TNF":[128],"for":[130],"refractory":[131],"sarcoid":[132],"uveitis,":[133],"although":[134],"their":[135],"use":[136],"requires":[137],"careful":[138],"risk-benefit":[139],"assessment":[140],"further":[142],"validation":[143],"controlled":[145],"trials.":[146]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2026-06-28T00:00:00"}