{"id":"https://openalex.org/W7166314030","doi":"https://doi.org/10.1177/13872877261462930","title":"Relationship between new-onset falls and neuroimaging markers of Alzheimer's disease in the UK Biobank","display_name":"Relationship between new-onset falls and neuroimaging markers of Alzheimer's disease in the UK Biobank","publication_year":2026,"publication_date":"2026-06-27","ids":{"openalex":"https://openalex.org/W7166314030","doi":"https://doi.org/10.1177/13872877261462930","pmid":"https://pubmed.ncbi.nlm.nih.gov/42363808"},"language":"en","primary_location":{"id":"doi:10.1177/13872877261462930","doi":"https://doi.org/10.1177/13872877261462930","is_oa":false,"landing_page_url":"https://doi.org/10.1177/13872877261462930","pdf_url":null,"source":{"id":"https://openalex.org/S25155249","display_name":"Journal of Alzheimer s Disease","issn_l":"1387-2877","issn":["1387-2877","1875-8908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer\u2019s Disease","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036779861","display_name":"Jacob S. Shaw","orcid":"https://orcid.org/0000-0002-7906-9945","observed_orcids":["https://orcid.org/0000-0002-7906-9945"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jacob S. Shaw","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":"https://orcid.org/0000-0002-7906-9945","affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081384802","display_name":"Michael J. C. Bray","orcid":"https://orcid.org/0000-0003-4650-1313","observed_orcids":["https://orcid.org/0000-0003-4650-1313"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J.C. Bray","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":"https://orcid.org/0000-0003-4650-1313","affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070419330","display_name":"Haris Iqbal Sair","orcid":"https://orcid.org/0000-0002-5077-0471","observed_orcids":["https://orcid.org/0000-0002-5077-0471"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haris I. Sair","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089692710","display_name":"Licia Luna","orcid":"https://orcid.org/0000-0003-3539-4831","observed_orcids":["https://orcid.org/0000-0003-3539-4831"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Licia P. Luna","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046529874","display_name":"Katherine J. Hunzinger","orcid":"https://orcid.org/0000-0002-4599-8543","observed_orcids":["https://orcid.org/0000-0002-4599-8543"]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine J. Hunzinger","raw_affiliation_strings":["Department of Exercise Science, Thomas Jefferson University, Philadelphia, PA, USA","Jefferson Center for Injury Research and Prevention, Thomas Jefferson University, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Exercise Science, Thomas Jefferson University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I149251103"]},{"raw_affiliation_string":"Jefferson Center for Injury Research and Prevention, Thomas Jefferson University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I149251103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036440846","display_name":"Esther S. Oh","orcid":"https://orcid.org/0000-0002-9638-5763","observed_orcids":["https://orcid.org/0000-0002-9638-5763"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Esther S. Oh","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069682721","display_name":"Paul B. Rosenberg","orcid":"https://orcid.org/0000-0003-1106-4299","observed_orcids":["https://orcid.org/0000-0003-1106-4299"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul B. Rosenberg","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107272178","display_name":"Matthew E. Peters","orcid":"https://orcid.org/0000-0002-5668-4566","observed_orcids":["https://orcid.org/0000-0002-5668-4566"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew E. Peters","raw_affiliation_strings":["Johns Hopkins University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036779861"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.51073322,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"112","issue":"4","first_page":"1843","last_page":"1854"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10114","display_name":"Balance, Gait, and Falls Prevention","score":0.10360000282526016,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8690000176429749}],"concepts":[{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.7930999994277954},{"id":"https://openalex.org/C116567970","wikidata":"https://www.wikidata.org/wiki/Q864217","display_name":"Biobank","level":2,"score":0.6876000165939331},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6651999950408936},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.48649999499320984},{"id":"https://openalex.org/C2778373026","wikidata":"https://www.wikidata.org/wiki/Q4738819","display_name":"Alzheimer's Disease Neuroimaging Initiative","level":4,"score":0.48179998993873596},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.47920000553131104},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.4147000014781952},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39250001311302185},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.37540000677108765},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.35989999771118164},{"id":"https://openalex.org/C166735990","wikidata":"https://www.wikidata.org/wiki/Q1750812","display_name":"Human factors and ergonomics","level":3,"score":0.2867000102996826},{"id":"https://openalex.org/C187155963","wikidata":"https://www.wikidata.org/wiki/Q629029","display_name":"Occupational safety and health","level":2,"score":0.2854999899864197},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.28529998660087585},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.27950000762939453},{"id":"https://openalex.org/C526869908","wikidata":"https://www.wikidata.org/wiki/Q3298118","display_name":"Suicide prevention","level":3,"score":0.2775000035762787},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.2732999920845032},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.27219998836517334},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2702000141143799},{"id":"https://openalex.org/C2778426673","wikidata":"https://www.wikidata.org/wiki/Q326921","display_name":"Concussion","level":4,"score":0.2653999924659729},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.2635999917984009},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.2547999918460846}],"mesh":[{"descriptor_ui":"D000058","descriptor_name":"Accidental Falls","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D000058","descriptor_name":"Accidental Falls","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D000097849","descriptor_name":"UK Biobank","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000097849","descriptor_name":"UK Biobank","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018070","descriptor_name":"Biological Specimen Banks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018070","descriptor_name":"Biological Specimen Banks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059906","descriptor_name":"Neuroimaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059906","descriptor_name":"Neuroimaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1177/13872877261462930","doi":"https://doi.org/10.1177/13872877261462930","is_oa":false,"landing_page_url":"https://doi.org/10.1177/13872877261462930","pdf_url":null,"source":{"id":"https://openalex.org/S25155249","display_name":"Journal of Alzheimer s Disease","issn_l":"1387-2877","issn":["1387-2877","1875-8908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer\u2019s Disease","raw_type":"journal-article"},{"id":"pmid:42363808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42363808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer's disease : JAD","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/4","display_name":"Quality education","score":0.4071967303752899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1495970686","display_name":null,"funder_award_id":"AGR01054771","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4106001577","display_name":null,"funder_award_id":"AGR01050515","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6015799054","display_name":null,"funder_award_id":"AGR01046543","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G7985714943","display_name":null,"funder_award_id":"AGR01071522","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1626921703","https://openalex.org/W1967082239","https://openalex.org/W1969311340","https://openalex.org/W1983825610","https://openalex.org/W1997764341","https://openalex.org/W2024287605","https://openalex.org/W2046458826","https://openalex.org/W2060689305","https://openalex.org/W2066360313","https://openalex.org/W2074205939","https://openalex.org/W2082704080","https://openalex.org/W2096242580","https://openalex.org/W2110065044","https://openalex.org/W2112586140","https://openalex.org/W2145328419","https://openalex.org/W2159861873","https://openalex.org/W2195457766","https://openalex.org/W2252502539","https://openalex.org/W2291289645","https://openalex.org/W2471406153","https://openalex.org/W2769568841","https://openalex.org/W2788507110","https://openalex.org/W2884402885","https://openalex.org/W2894224341","https://openalex.org/W2917160072","https://openalex.org/W2947590464","https://openalex.org/W3016980863","https://openalex.org/W3045563919","https://openalex.org/W3045995317","https://openalex.org/W3097891538","https://openalex.org/W3183431821","https://openalex.org/W3196953909","https://openalex.org/W3206251168","https://openalex.org/W4210468844","https://openalex.org/W4281717669","https://openalex.org/W4292471401","https://openalex.org/W4308369609","https://openalex.org/W4322757582","https://openalex.org/W4362705667","https://openalex.org/W4377012437","https://openalex.org/W4384828049","https://openalex.org/W4386625349","https://openalex.org/W4396560090","https://openalex.org/W4399707968","https://openalex.org/W4399917596","https://openalex.org/W4400103454","https://openalex.org/W4402617464","https://openalex.org/W4402983648","https://openalex.org/W4406687197","https://openalex.org/W4408522206","https://openalex.org/W4408922066","https://openalex.org/W4410105049","https://openalex.org/W4410787397","https://openalex.org/W4411230028","https://openalex.org/W4411795650"],"related_works":[],"abstract_inverted_index":{"BackgroundWhile":[0],"Alzheimer's":[1],"disease":[2],"(AD)":[3],"is":[4,18,224],"a":[5,19,203],"known":[6],"risk":[7],"factor":[8],"for":[9,189],"falls,":[10,116,126],"the":[11,63,78,103,134,140,158],"association":[12],"between":[13,33,53,201],"falls":[14,35,55,88,94,100,136,145,160,211,216],"and":[15,39,41,56,82,143,166],"incident":[16],"AD":[17,245],"growing":[20],"area":[21],"of":[22,26,44,59,73,80,87,151,180,205,210,235],"study.ObjectiveThe":[23],"primary":[24],"aim":[25,48],"this":[27],"analysis":[28,114],"was":[29,49,67,174],"to":[30,50,107,131,244],"examine":[31],"associations":[32,52],"new-onset":[34,54,215],"in":[36,112,133,139,157],"older":[37,76,206],"adults":[38,207],"neuroimaging":[40,57,81],"plasma":[42,178],"biomarkers":[43],"AD.":[45],"A":[46],"secondary":[47,243],"evaluate":[51],"markers":[58],"motor":[60],"dysfunction.MethodsData":[61],"from":[62],"UK":[64],"Biobank":[65],"study":[66,90,213],"utilized.":[68],"Participants":[69],"were":[70,110,217],"70":[71],"years":[72],"age":[74],"or":[75,171],"at":[77,89,212],"date":[79],"had":[83,147,162],"no":[84],"reported":[85],"history":[86,101,209],"enrollment.":[91],"To":[92],"determine":[93],"status,":[95],"participants":[96],"self-reported":[97],"data":[98],"on":[99],"within":[102],"last":[104],"year":[105],"prior":[106],"neuroimaging.Results15,447":[108],"individuals":[109,132,138,156],"included":[111],"our":[113],"(No":[115],"N":[117,122,127],"=":[118,123,128],"12,522;":[119],"One":[120,141,170],"fall,":[121],"2,199,":[124],"Multiple":[125,144,159],"726).":[129],"Compared":[130],"No":[135],"group,":[137],"fall":[142,173],"group":[146,161],"significantly":[148,163,200],"higher":[149,177],"volumes":[150],"white":[152,236],"matter":[153,237],"hyperintensities,":[154,238],"while":[155],"lower":[164],"left":[165],"right":[167],"hippocampal":[168,221],"volumes.":[169],"more":[172],"associated":[175,218,225],"with":[176,219,226],"levels":[179],"pTau181,":[181],"which":[182,223,239],"did":[183,197],"not":[184,198],"remain":[185],"significant":[186],"after":[187],"adjusting":[188],"multiple":[190],"comparisons.":[191],"Plasma":[192],"amyloid-\u03b2":[193],"42/amyloid-\u03b2":[194],"40":[195],"ratio":[196],"differ":[199],"groups.ConclusionsIn":[202],"sample":[204],"without":[208],"enrollment,":[214],"decreased":[220],"volumes,":[222],"prodromal":[227],"AD,":[228],"as":[229,231],"well":[230],"an":[232],"increased":[233],"volume":[234],"may":[240],"also":[241],"emerge":[242],"pathology.":[246]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-06-28T00:00:00"}