{"id":"https://openalex.org/W7166201246","doi":"https://doi.org/10.7554/elife.107855.3.sa2","title":"Author response: Deciphering interferon functions in avian influenza using receptor knockout models in the natural host","display_name":"Author response: Deciphering interferon functions in avian influenza using receptor knockout models in the natural host","publication_year":2026,"publication_date":"2026-06-26","ids":{"openalex":"https://openalex.org/W7166201246","doi":"https://doi.org/10.7554/elife.107855.3.sa2"},"language":"en","primary_location":{"id":"doi:10.7554/elife.107855.3.sa2","doi":"https://doi.org/10.7554/elife.107855.3.sa2","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.107855.3.sa2","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"volume":null,"type":"peer-review","is_traditional":false,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.107855.3.sa2","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087561163","display_name":"Mohanned Naif Alhussien","orcid":"https://orcid.org/0000-0002-3833-9953","observed_orcids":["https://orcid.org/0000-0002-3833-9953"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mohanned Naif Alhussien","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137580548","display_name":"Hanna-Kaisa Vikkula","orcid":"https://orcid.org/0009-0000-3208-1886","observed_orcids":["https://orcid.org/0009-0000-3208-1886"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hanna Kaisa Vikkula","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004929258","display_name":"Romina Klinger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Romina Klinger","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036665486","display_name":"Christian Zenner","orcid":"https://orcid.org/0000-0003-4035-8456","observed_orcids":["https://orcid.org/0000-0003-4035-8456"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Zenner","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102932164","display_name":"Simon P. Fr\u00fch","orcid":"https://orcid.org/0000-0002-4757-8315","observed_orcids":["https://orcid.org/0000-0002-4757-8315"]},"institutions":[{"id":"https://openalex.org/I8204097","display_name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","ror":"https://ror.org/05591te55","country_code":"DE","type":"education","lineage":["https://openalex.org/I8204097"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Simon P Frueh","raw_affiliation_strings":["Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","institution_ids":["https://openalex.org/I8204097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117367243","display_name":"Rashi Negi","orcid":"https://orcid.org/0009-0006-4918-3647","observed_orcids":["https://orcid.org/0009-0006-4918-3647"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rashi Negi","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057915994","display_name":"Theresa von Heyl","orcid":"https://orcid.org/0000-0001-9936-5752","observed_orcids":["https://orcid.org/0000-0001-9936-5752"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Theresa von Heyl","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114312894","display_name":"Sabrina Schleibinger","orcid":"https://orcid.org/0009-0002-1264-4113","observed_orcids":["https://orcid.org/0009-0002-1264-4113"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sabrina Schleibinger","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133356494","display_name":"Milena Brunner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Milena Brunner","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084908954","display_name":"T.V.L. Berghof","orcid":"https://orcid.org/0000-0003-4879-6784","observed_orcids":["https://orcid.org/0000-0003-4879-6784"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tom VL Berghof","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137583513","display_name":"Leora Avolio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Leora Avolio","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5137555426","display_name":"Arne Reich","orcid":"https://orcid.org/0009-0008-8598-0488","observed_orcids":["https://orcid.org/0009-0008-8598-0488"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Arne Reich","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110676886","display_name":"Benjamin Schade","orcid":"https://orcid.org/0009-0007-6725-6130","observed_orcids":["https://orcid.org/0009-0007-6725-6130"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Benjamin Schade","raw_affiliation_strings":["Bavarian Animal Health Service"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bavarian Animal Health Service","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117367242","display_name":"Bassel A Abukhadra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189991","display_name":"University of Veterinary Medicine Hannover, Foundation","ror":"https://ror.org/015qjqf64","country_code":"DE","type":"education","lineage":["https://openalex.org/I189991"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Bassel Aboukhadra","raw_affiliation_strings":["University of Veterinary Medicine Hannover, Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Veterinary Medicine Hannover, Foundation","institution_ids":["https://openalex.org/I189991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084056885","display_name":"Silke Rautenschlein","orcid":"https://orcid.org/0000-0002-8177-3755","observed_orcids":["https://orcid.org/0000-0002-8177-3755"]},"institutions":[{"id":"https://openalex.org/I189991","display_name":"University of Veterinary Medicine Hannover, Foundation","ror":"https://ror.org/015qjqf64","country_code":"DE","type":"education","lineage":["https://openalex.org/I189991"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Silke Rautenschlein","raw_affiliation_strings":["University of Veterinary Medicine Hannover, Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Veterinary Medicine Hannover, Foundation","institution_ids":["https://openalex.org/I189991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000897448","display_name":"Rudolf Preisinger","orcid":"https://orcid.org/0000-0002-4873-0462","observed_orcids":["https://orcid.org/0000-0002-4873-0462"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rudolf Preisinger","raw_affiliation_strings":["EW GROUP GmbH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EW GROUP GmbH","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067953447","display_name":"Hicham Sid","orcid":"https://orcid.org/0000-0002-5608-8166","observed_orcids":["https://orcid.org/0000-0002-5608-8166"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hicham Sid","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078276798","display_name":"Benjamin Schusser","orcid":"https://orcid.org/0000-0002-9990-1890","observed_orcids":["https://orcid.org/0000-0002-9990-1890"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Benjamin Schusser","raw_affiliation_strings":["Technical University of Munich"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technical University of Munich","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.021700000390410423,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interferon","display_name":"interferon","score":0.9430000185966492},{"id":"https://openalex.org/keywords/avian-influenza","display_name":"avian influenza","score":0.9860000014305115},{"id":"https://openalex.org/keywords/natural-hosts","display_name":"natural hosts","score":0.7670000195503235},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.4819999933242798},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.4390000104904175}],"concepts":[{"id":"https://openalex.org/C2776178377","wikidata":"https://www.wikidata.org/wiki/Q188269","display_name":"Interferon","level":2,"score":0.7142999768257141},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6777999997138977},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6061999797821045},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.5774000287055969},{"id":"https://openalex.org/C519248777","wikidata":"https://www.wikidata.org/wiki/Q160122","display_name":"Influenza A virus subtype H5N1","level":3,"score":0.5575000047683716},{"id":"https://openalex.org/C2776954689","wikidata":"https://www.wikidata.org/wiki/Q21100537","display_name":"RIG-I","level":4,"score":0.5188000202178955},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.5073999762535095},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.43160000443458557},{"id":"https://openalex.org/C2776608160","wikidata":"https://www.wikidata.org/wiki/Q4785462","display_name":"Natural (archaeology)","level":2,"score":0.3978999853134155},{"id":"https://openalex.org/C3019819676","wikidata":"https://www.wikidata.org/wiki/Q43987","display_name":"Highly pathogenic","level":4,"score":0.3682999908924103},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3653999865055084},{"id":"https://openalex.org/C77957584","wikidata":"https://www.wikidata.org/wiki/Q1133550","display_name":"Gene knockout","level":3,"score":0.3260999917984009},{"id":"https://openalex.org/C2778278966","wikidata":"https://www.wikidata.org/wiki/Q6046488","display_name":"Interferon type I","level":3,"score":0.30230000615119934},{"id":"https://openalex.org/C82988372","wikidata":"https://www.wikidata.org/wiki/Q5628866","display_name":"H5N1 genetic structure","level":5,"score":0.2775999903678894},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.27649998664855957},{"id":"https://openalex.org/C2777546802","wikidata":"https://www.wikidata.org/wiki/Q834390","display_name":"Influenza A virus","level":3,"score":0.2630000114440918},{"id":"https://openalex.org/C134474686","wikidata":"https://www.wikidata.org/wiki/Q21111069","display_name":"MDA5","level":5,"score":0.25589999556541443},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.2549999952316284}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7554/elife.107855.3.sa2","doi":"https://doi.org/10.7554/elife.107855.3.sa2","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.107855.3.sa2","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"}],"best_oa_location":{"id":"doi:10.7554/elife.107855.3.sa2","doi":"https://doi.org/10.7554/elife.107855.3.sa2","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.107855.3.sa2","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7163010560","https://openalex.org/W4414152615","https://openalex.org/W4414089711","https://openalex.org/W7171043066","https://openalex.org/W4299826780","https://openalex.org/W2971706738","https://openalex.org/W4206336984","https://openalex.org/W7213250303","https://openalex.org/W2039651729","https://openalex.org/W4394894468"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-06-27T00:00:00"}