{"id":"https://openalex.org/W7166136388","doi":"https://doi.org/10.7189/jogh.16.04095","title":"Habitual physical activity and sarcopenia: a systematic review and meta-analysis of prospective cohort studies","display_name":"Habitual physical activity and sarcopenia: a systematic review and meta-analysis of prospective cohort studies","publication_year":2026,"publication_date":"2026-06-26","ids":{"openalex":"https://openalex.org/W7166136388","doi":"https://doi.org/10.7189/jogh.16.04095","pmid":"https://pubmed.ncbi.nlm.nih.gov/42359826"},"language":"en","primary_location":{"id":"doi:10.7189/jogh.16.04095","doi":"https://doi.org/10.7189/jogh.16.04095","is_oa":true,"landing_page_url":"https://doi.org/10.7189/jogh.16.04095","pdf_url":"https://jogh.org/wp-content/uploads/2026/06/jogh-16-04095n.pdf","source":{"id":"https://openalex.org/S2736978234","display_name":"Journal of Global Health","issn_l":"2047-2978","issn":["2047-2978","2047-2986"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311848","host_organization_name":"Edinburgh University Global Health Society","host_organization_lineage":["https://openalex.org/P4310311848"],"host_organization_lineage_names":["Edinburgh University Global Health Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Global Health","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jogh.org/wp-content/uploads/2026/06/jogh-16-04095n.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Dacheng Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dacheng Dai","raw_affiliation_strings":["Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052165206","display_name":"Fangfang Xie","orcid":"https://orcid.org/0000-0003-2668-460X","observed_orcids":["https://orcid.org/0000-0003-2668-460X"]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fangfang Xie","raw_affiliation_strings":["School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China","Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]},{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128504273","display_name":"Jiahe Cui","orcid":"https://orcid.org/0009-0006-1649-9012","observed_orcids":["https://orcid.org/0009-0006-1649-9012"]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiahe Cui","raw_affiliation_strings":["Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Siyu Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siyu Wang","raw_affiliation_strings":["Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012150267","display_name":"Junhao Cai","orcid":"https://orcid.org/0009-0004-0206-7011","observed_orcids":["https://orcid.org/0009-0004-0206-7011"]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junhao Cai","raw_affiliation_strings":["Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064479122","display_name":"G Q Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guimao Wang","raw_affiliation_strings":["Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012371721","display_name":"Fei Yao","orcid":"https://orcid.org/0000-0002-7446-2019","observed_orcids":["https://orcid.org/0000-0002-7446-2019"]},"institutions":[{"id":"https://openalex.org/I4210098460","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210098460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fei Yao","raw_affiliation_strings":["School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China","Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]},{"raw_affiliation_string":"Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210098460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210098460"],"apc_list":{"value":1200,"currency":"USD","value_usd":1200},"apc_paid":{"value":1200,"currency":"USD","value_usd":1200},"fwci":1.8487,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.86229996,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"16","issue":null,"first_page":"04095","last_page":"04095"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/habitual-physical-activity","display_name":"physical activity behavior","score":0.9890000224113464},{"id":"https://openalex.org/keywords/sarcopenia","display_name":"sarcopenia","score":1.0},{"id":"https://openalex.org/keywords/skeletal-muscle-protein-synthesis","display_name":"skeletal muscle protein synthesis","score":0.7310000061988831},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.9850000143051147},{"id":"https://openalex.org/keywords/physical-activity-guidelines-compliance","display_name":"physical activity guidelines compliance","score":0.828000009059906},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6489999890327454},{"id":"https://openalex.org/keywords/reverse-causality","display_name":"reverse causality","score":0.6209999918937683}],"concepts":[{"id":"https://openalex.org/C2776214593","wikidata":"https://www.wikidata.org/wiki/Q1787939","display_name":"Sarcopenia","level":2,"score":0.7839999794960022},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7784000039100647},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.7084000110626221},{"id":"https://openalex.org/C3020255362","wikidata":"https://www.wikidata.org/wiki/Q747883","display_name":"Physical activity","level":2,"score":0.6290000081062317},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5619000196456909},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.5340999960899353},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4399000108242035},{"id":"https://openalex.org/C2988918651","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Muscle strength","level":2,"score":0.39750000834465027},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.39419999718666077},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3919999897480011},{"id":"https://openalex.org/C3019887659","wikidata":"https://www.wikidata.org/wiki/Q191089","display_name":"Older people","level":2,"score":0.3336000144481659},{"id":"https://openalex.org/C2992343062","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Muscle mass","level":2,"score":0.2989000082015991},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.29739999771118164},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.29109999537467957},{"id":"https://openalex.org/C3017819807","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Healthy aging","level":2,"score":0.2856000065803528},{"id":"https://openalex.org/C192091488","wikidata":"https://www.wikidata.org/wiki/Q3048982","display_name":"Cohort effect","level":3,"score":0.28279998898506165},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.28029999136924744},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.26260000467300415}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D055948","descriptor_name":"Sarcopenia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.7189/jogh.16.04095","doi":"https://doi.org/10.7189/jogh.16.04095","is_oa":true,"landing_page_url":"https://doi.org/10.7189/jogh.16.04095","pdf_url":"https://jogh.org/wp-content/uploads/2026/06/jogh-16-04095n.pdf","source":{"id":"https://openalex.org/S2736978234","display_name":"Journal of Global Health","issn_l":"2047-2978","issn":["2047-2978","2047-2986"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311848","host_organization_name":"Edinburgh University Global Health Society","host_organization_lineage":["https://openalex.org/P4310311848"],"host_organization_lineage_names":["Edinburgh University Global Health Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Global Health","raw_type":"journal-article"},{"id":"pmid:42359826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42359826","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of global health","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13307538","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13307538/pdf/jogh-16-04095.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Glob Health","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7189/jogh.16.04095","doi":"https://doi.org/10.7189/jogh.16.04095","is_oa":true,"landing_page_url":"https://doi.org/10.7189/jogh.16.04095","pdf_url":"https://jogh.org/wp-content/uploads/2026/06/jogh-16-04095n.pdf","source":{"id":"https://openalex.org/S2736978234","display_name":"Journal of Global Health","issn_l":"2047-2978","issn":["2047-2978","2047-2986"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311848","host_organization_name":"Edinburgh University Global Health Society","host_organization_lineage":["https://openalex.org/P4310311848"],"host_organization_lineage_names":["Edinburgh University Global Health Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Global Health","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5710927844047546}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320326704","display_name":"Shanghai University of Traditional Chinese Medicine","ror":"https://ror.org/00z27jk27"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7166136388.pdf","grobid_xml":"https://content.openalex.org/works/W7166136388.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1847471344","https://openalex.org/W1971299878","https://openalex.org/W1987823791","https://openalex.org/W1991681137","https://openalex.org/W1995381409","https://openalex.org/W2033234733","https://openalex.org/W2064945988","https://openalex.org/W2082840583","https://openalex.org/W2084254617","https://openalex.org/W2085481573","https://openalex.org/W2137944397","https://openalex.org/W2157769075","https://openalex.org/W2407511756","https://openalex.org/W2429359053","https://openalex.org/W2611701272","https://openalex.org/W2616778070","https://openalex.org/W2897513125","https://openalex.org/W2898510867","https://openalex.org/W2900726805","https://openalex.org/W2941075934","https://openalex.org/W3047131348","https://openalex.org/W3108106255","https://openalex.org/W3138073779","https://openalex.org/W3150099370","https://openalex.org/W3191864380","https://openalex.org/W3216479690","https://openalex.org/W3216722244","https://openalex.org/W4200392975","https://openalex.org/W4211144975","https://openalex.org/W4220921480","https://openalex.org/W4323923461","https://openalex.org/W4379473214","https://openalex.org/W4395085321","https://openalex.org/W4401010500","https://openalex.org/W4408849366","https://openalex.org/W4410845873","https://openalex.org/W4413326218","https://openalex.org/W4414418007"],"related_works":[],"abstract_inverted_index":{"Background:":[0],"Habitual":[1],"physical":[2,83],"activity":[3,84],"(HPA)":[4],"has":[5],"been":[6],"associated":[7,148,191,221],"with":[8,126,149,182,192,222],"a":[9,28,37,123,150,193,223,230],"lower":[10,152,224],"risk":[11,153,195,225],"of":[12,67,145,154,217,226],"sarcopenia":[13,155],"by":[14,111,177,180],"enhancing":[15],"skeletal":[16],"muscle":[17],"protein":[18],"synthesis":[19],"and":[20,40,48,62,69,86,91,99,117,179],"suppressing":[21],"systemic":[22],"inflammation.":[23],"However,":[24,234],"the":[25,44,54,70,80,104,127,158,236,250],"evidence":[26],"for":[27,75,256],"long-term":[29],"protective":[30,169,232],"association":[31,45,170],"remains":[32],"inconclusive.":[33],"Therefore,":[34],"we":[35],"conducted":[36],"systematic":[38],"review":[39],"meta-analysis":[41,133],"to":[42,60,157,197,214,248],"quantify":[43],"between":[46,82],"HPA":[47,146,188,199,218],"sarcopenia.":[49,87],"Methods:":[50],"We":[51,88],"searched":[52],"PubMed,":[53],"Cochrane":[55],"Library,":[56],"EMBASE,":[57],"Cumulative":[58],"Index":[59],"Nursing":[61],"Allied":[63],"Health":[64],"Literature,":[65],"Web":[66],"Science,":[68],"China":[71],"National":[72],"Knowledge":[73],"Infrastructure":[74],"prospective":[76,136,244],"cohort":[77,137],"studies":[78,138,245],"on":[79],"relationship":[81],"(PA)":[85],"selected":[89],"English":[90],"Chinese-language":[92],"literature":[93],"published":[94],"before":[95],"6":[96],"October":[97],"2025,":[98],"assessed":[100],"study":[101],"quality":[102],"using":[103,122],"Newcastle-Ottawa":[105],"Scale.":[106],"Data":[107],"were":[108,147],"statistically":[109],"synthesised":[110],"calculating":[112],"pooled":[113],"relative":[114],"risks":[115],"(RRs)":[116],"95%":[118,164,204],"confidence":[119],"intervals":[120],"(CIs)":[121],"random-effects":[124],"model":[125],"generic":[128],"inverse-variance":[129],"method.":[130],"Results:":[131],"This":[132,168],"included":[134],"nine":[135],"involving":[139],"21":[140],"265":[141],"participants.":[142],"High":[143],"levels":[144,160,200,216],"significantly":[151],"compared":[156,196],"low":[159,198],"(RR":[161,201],"=":[162,166,202,206],"0.55;":[163],"CI":[165,205],"0.44-0.67).":[167],"remained":[171],"consistent":[172],"in":[173,239],"subgroup":[174],"analyses":[175],"stratified":[176],"gender":[178],"compliance":[181],"international":[183],"PA":[184,240,252],"guidelines.":[185],"Furthermore,":[186],"moderate":[187,213],"was":[189],"also":[190],"reduced":[194],"0.73;":[203],"0.50-0.96).":[207],"Conclusions:":[208],"Our":[209],"analysis":[210],"indicates":[211],"that":[212],"high":[215],"are":[219,246],"independently":[220],"sarcopenia,":[227],"serving":[228],"as":[229],"significant":[231],"factor.":[233],"given":[235],"methodological":[237],"heterogeneity":[238],"measurement,":[241],"further":[242],"high-quality":[243],"needed":[247],"clarify":[249],"optimal":[251],"dose":[253],"while":[254],"accounting":[255],"potential":[257],"reverse":[258],"causality.":[259],"Registration:":[260],"PROSPERO:":[261],"CRD420251162529.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2026-06-27T00:00:00"}