{"id":"https://openalex.org/W7166108649","doi":"https://doi.org/10.48048/tis.2026.13458","title":"Evaluation of Anti-Ulcerogenic Effect of Castanopsis costata Extract Against Experimental Gastric Ulcer in Rats","display_name":"Evaluation of Anti-Ulcerogenic Effect of Castanopsis costata Extract Against Experimental Gastric Ulcer in Rats","publication_year":2026,"publication_date":"2026-04-30","ids":{"openalex":"https://openalex.org/W7166108649","doi":"https://doi.org/10.48048/tis.2026.13458"},"language":"en","primary_location":{"id":"doi:10.48048/tis.2026.13458","doi":"https://doi.org/10.48048/tis.2026.13458","is_oa":true,"landing_page_url":"https://doi.org/10.48048/tis.2026.13458","pdf_url":"https://tis.wu.ac.th/index.php/tis/article/download/13458/2334","source":{"id":"https://openalex.org/S4210171953","display_name":"Trends in Sciences","issn_l":"2774-0226","issn":["2774-0226"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310319383","host_organization_name":"Walailak University","host_organization_lineage":["https://openalex.org/P4310319383"],"host_organization_lineage_names":["Walailak University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://tis.wu.ac.th/index.php/tis/article/download/13458/2334","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008953256","display_name":"Maulana Yusuf Alkandahri","orcid":"https://orcid.org/0000-0003-3402-4265","observed_orcids":["https://orcid.org/0000-0003-3402-4265"]},"institutions":[{"id":"https://openalex.org/I4405255078","display_name":"Universitas Buana Perjuangan Karawang","ror":"https://ror.org/02khkrx67","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405255078"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Maulana Yusuf Alkandahri","raw_affiliation_strings":["Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia","institution_ids":["https://openalex.org/I4405255078"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078818362","display_name":"Asman Sadino","orcid":"https://orcid.org/0000-0002-2289-9729","observed_orcids":["https://orcid.org/0000-0002-2289-9729"]},"institutions":[{"id":"https://openalex.org/I4210121505","display_name":"Universitas Garut","ror":"https://ror.org/02pa24904","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210121505"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Asman Sadino","raw_affiliation_strings":["Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Garut, Garut, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Garut, Garut, Indonesia","institution_ids":["https://openalex.org/I4210121505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113079648","display_name":"Wilda Fhitriany Usman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108557","display_name":"Sultan Agung Islamic University","ror":"https://ror.org/015hejj83","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210108557"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Wilda Fhitriany Usman","raw_affiliation_strings":["Pharmacist Professional Education Study Program, Faculty of Pharmacy, Universitas Islam Sultan Agung, Semarang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacist Professional Education Study Program, Faculty of Pharmacy, Universitas Islam Sultan Agung, Semarang, Indonesia","institution_ids":["https://openalex.org/I4210108557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074010272","display_name":"Zulpakor Oktoba","orcid":"https://orcid.org/0000-0001-5478-8751","observed_orcids":["https://orcid.org/0000-0001-5478-8751"]},"institutions":[{"id":"https://openalex.org/I12833781","display_name":"Lampung University","ror":"https://ror.org/05wtz9f44","country_code":"ID","type":"education","lineage":["https://openalex.org/I12833781"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Zulpakor Oktoba","raw_affiliation_strings":["Department of Pharmacy, Faculty of Medicine, Universitas Lampung, Bandar Lampung, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Faculty of Medicine, Universitas Lampung, Bandar Lampung, Indonesia","institution_ids":["https://openalex.org/I12833781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016717654","display_name":"Aprilya Sri Rachmayanti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aprilya Sri Rachmayanti","raw_affiliation_strings":["Pharmacist Professional Education Study Program, Institut Kesehatan Mitra Bunda, Batam, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacist Professional Education Study Program, Institut Kesehatan Mitra Bunda, Batam, Indonesia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045147019","display_name":"Rastria Meilanda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rastria Meilanda","raw_affiliation_strings":["Department of Pharmacy, Institut Kesehatan Mitra Bunda, Batam, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Institut Kesehatan Mitra Bunda, Batam, Indonesia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003704457","display_name":"Ermi Abriyani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405255078","display_name":"Universitas Buana Perjuangan Karawang","ror":"https://ror.org/02khkrx67","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405255078"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Ermi Abriyani","raw_affiliation_strings":["Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia","institution_ids":["https://openalex.org/I4405255078"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079063559","display_name":"Dani Sujana","orcid":"https://orcid.org/0000-0003-0562-7008","observed_orcids":["https://orcid.org/0000-0003-0562-7008"]},"institutions":[{"id":"https://openalex.org/I4405276663","display_name":"Institut Kesehatan Karsa Husada Garut","ror":"https://ror.org/05vax4920","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405276663"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Dani Sujana","raw_affiliation_strings":["Diploma Program of Pharmacy, Karsa Husada Garut College of Health Sciences, Garut, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diploma Program of Pharmacy, Karsa Husada Garut College of Health Sciences, Garut, Indonesia","institution_ids":["https://openalex.org/I4405276663"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094278693","display_name":"Andi Nurzakiah Amal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405255078","display_name":"Universitas Buana Perjuangan Karawang","ror":"https://ror.org/02khkrx67","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405255078"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Andi Nurzakiah Amal","raw_affiliation_strings":["Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia","institution_ids":["https://openalex.org/I4405255078"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5093525658","display_name":"Sigit Roma Rezki Harahap","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405255078","display_name":"Universitas Buana Perjuangan Karawang","ror":"https://ror.org/02khkrx67","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405255078"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Sigit Roma Rezki Harahap","raw_affiliation_strings":["Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, Indonesia","institution_ids":["https://openalex.org/I4405255078"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"10","first_page":"13458","last_page":"13458"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.8291000127792358,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.8291000127792358,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.06360000371932983,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.03370000049471855,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiulcer-activity","display_name":"antiulcer activity","score":0.8600000143051147},{"id":"https://openalex.org/keywords/gastric-ulcer","display_name":"gastric ulcer","score":0.9869999885559082},{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":0.9340000152587891},{"id":"https://openalex.org/keywords/ethanol-induced-gastric-lesions","display_name":"ethanol-induced gastric injury","score":0.7480000257492065},{"id":"https://openalex.org/keywords/ethanolic-plant-extract","display_name":"ethanolic plant extract","score":0.9179999828338623},{"id":"https://openalex.org/keywords/anti-inflammatory-cytokines","display_name":"anti-inflammatory cytokines","score":0.7620000243186951},{"id":"https://openalex.org/keywords/prostaglandin-e2","display_name":"prostaglandin E2","score":0.9259999990463257},{"id":"https://openalex.org/keywords/gastric-mucosal-injury","display_name":"gastric mucosal injury","score":0.6759999990463257},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"traditional medicine","score":0.6309999823570251}],"concepts":[{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6628999710083008},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.5992000102996826},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5228999853134155},{"id":"https://openalex.org/C160492267","wikidata":"https://www.wikidata.org/wiki/Q319616","display_name":"Pharmacognosy","level":4,"score":0.5001999735832214},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4440999925136566},{"id":"https://openalex.org/C2779969877","wikidata":"https://www.wikidata.org/wiki/Q861699","display_name":"Phytotherapy","level":3,"score":0.4122999906539917},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4117000102996826},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37560001015663147},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3617999851703644},{"id":"https://openalex.org/C2781443798","wikidata":"https://www.wikidata.org/wiki/Q383249","display_name":"Gastric mucosa","level":3,"score":0.3398999869823456},{"id":"https://openalex.org/C2781380062","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Folk medicine","level":2,"score":0.33799999952316284},{"id":"https://openalex.org/C2777504413","wikidata":"https://www.wikidata.org/wiki/Q846270","display_name":"Gastric acid","level":3,"score":0.32010000944137573},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.31349998712539673},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.3122999966144562},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.3059999942779541},{"id":"https://openalex.org/C57992300","wikidata":"https://www.wikidata.org/wiki/Q2066956","display_name":"Potency","level":3,"score":0.29490000009536743},{"id":"https://openalex.org/C2779137044","wikidata":"https://www.wikidata.org/wiki/Q7577827","display_name":"Spirillaceae","level":4,"score":0.2946999967098236},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.29440000653266907},{"id":"https://openalex.org/C3019114686","wikidata":"https://www.wikidata.org/wiki/Q3089676","display_name":"Rat model","level":2,"score":0.28040000796318054},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.2797999978065491},{"id":"https://openalex.org/C2780073392","wikidata":"https://www.wikidata.org/wiki/Q7878798","display_name":"Ulcer index","level":4,"score":0.26440000534057617},{"id":"https://openalex.org/C3018233652","wikidata":"https://www.wikidata.org/wiki/Q101965","display_name":"Experimental research","level":2,"score":0.25519999861717224}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.48048/tis.2026.13458","doi":"https://doi.org/10.48048/tis.2026.13458","is_oa":true,"landing_page_url":"https://doi.org/10.48048/tis.2026.13458","pdf_url":"https://tis.wu.ac.th/index.php/tis/article/download/13458/2334","source":{"id":"https://openalex.org/S4210171953","display_name":"Trends in Sciences","issn_l":"2774-0226","issn":["2774-0226"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310319383","host_organization_name":"Walailak University","host_organization_lineage":["https://openalex.org/P4310319383"],"host_organization_lineage_names":["Walailak University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.48048/tis.2026.13458","doi":"https://doi.org/10.48048/tis.2026.13458","is_oa":true,"landing_page_url":"https://doi.org/10.48048/tis.2026.13458","pdf_url":"https://tis.wu.ac.th/index.php/tis/article/download/13458/2334","source":{"id":"https://openalex.org/S4210171953","display_name":"Trends in Sciences","issn_l":"2774-0226","issn":["2774-0226"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310319383","host_organization_name":"Walailak University","host_organization_lineage":["https://openalex.org/P4310319383"],"host_organization_lineage_names":["Walailak University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320327880","display_name":"Lembaga Penelitian dan Pengabdian Kepada Masyarakat","ror":null},{"id":"https://openalex.org/F4320336199","display_name":"Direktorat Riset dan Pengabdian Masyarakat","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7166108649.pdf","grobid_xml":"https://content.openalex.org/works/W7166108649.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2183949312","https://openalex.org/W7220038150","https://openalex.org/W4400046062","https://openalex.org/W2252862774","https://openalex.org/W4401549330","https://openalex.org/W7097586211","https://openalex.org/W2051662184","https://openalex.org/W4408886585","https://openalex.org/W2993438310","https://openalex.org/W4386269215"],"abstract_inverted_index":{"Gastrointestinal":[0],"diseases,":[1],"such":[2],"as":[3,110,112,125,127],"gastric":[4,118,166,244,252],"ulcer":[5,245],"(GU),":[6],"are":[7,25],"caused":[8],"by":[9,69,193],"damage":[10],"to":[11,56,116,135,152,225],"the":[12,41,89,137,154,169,179,195],"GM,":[13],"alcohol":[14],"consumption,":[15],"NSAIDs":[16],"(specifically":[17],"ketorolac),":[18],"and":[19,79,97,105,108,149,174,186,189,202,212,231,250,271],"Helicobacter":[20],"pylori.":[21],"Currently,":[22],"several":[23],"plants":[24],"effective":[26],"in":[27,62,88,147,150,184,187,209,246,269,272],"treating":[28],"GU,":[29],"including":[30],"Castanopsis":[31,219,237,262],"costata.":[32],"Until":[33],"now,":[34],"there":[35],"has":[36],"been":[37],"no":[38],"report":[39],"regarding":[40],"antiulcerogenic":[42,58,207],"effects":[43,138,208],"of":[44,47,60,66,121,130,139,156,171,181,197,236,261],"ethanolic":[45,234,259],"extract":[46,235,260],"C.":[48],"costata":[49,220,238,263],"(EECc)":[50],"reported.":[51],"Therefore,":[52],"this":[53,102],"research":[54],"aimed":[55],"test":[57],"potential":[59],"EECc":[61,94,164,205],"3":[63],"rat":[64,216],"models":[65],"GU":[67,215],"induced":[68],"ethanol":[70],"(EtOH)":[71],"1":[72],"mL":[73],"orally,":[74],"ketorolac":[75],"(30":[76],"mg/kg":[77,99],"orally),":[78],"H.":[80,157,182,213],"pylori":[81,143,158,183,267],"(1.0\u00d7109":[82],"CFU":[83],"intragastrically).":[84],"Each":[85],"treatment":[86],"group":[87],"experimental":[90,243],"model":[91],"was":[92,145],"given":[93],"50,":[95],"100,":[96],"200":[98],"orally.":[100],"In":[101],"context,":[103],"GpH":[104],"GV,":[106],"FA":[107],"TA,":[109],"well":[111,126],"UI,":[113],"were":[114,132],"measured":[115],"assess":[117,153],"function.":[119],"Measurements":[120],"inflammatory":[122],"cytokines":[123],"levels,":[124],"histopathological":[128],"examination":[129],"tissue,":[131],"carried":[133],"out":[134],"determine":[136],"organ":[140],"damage.":[141],"Anti-H.":[142],"activity":[144,241,268],"tested":[146],"vitro":[148,185,270],"vivo":[151],"inhibition":[155],"growth.":[159],"The":[160,233,254],"results":[161],"showed":[162],"that":[163,258],"improved":[165,190],"function,":[167],"reduced":[168],"levels":[170],"TNF-\u03b1,":[172],"IL-1\u03b2,":[173],"IL-6,":[175],"increased":[176],"PGE2,":[177],"inhibited":[178],"growth":[180],"vivo,":[188],"tissue":[191],"architecture":[192],"reducing":[194],"severity":[196],"GM":[198],"injury,":[199],"leukocyte":[200],"infiltration,":[201],"bleeding.":[203],"Moreover,":[204],"had":[206],"EtOH-,":[210],"ketorolac-,":[211],"pylori-induced":[214,251],"models.":[217],"HIGHLIGHTS":[218],"is":[221],"a":[222],"traditional":[223],"medicine":[224],"treat":[226],"fever,":[227],"various":[228],"digestive":[229],"disorders,":[230],"analgesic.":[232],"exhibited":[239],"anti-ulcerogenic":[240],"against":[242],"rats":[247],"(ethanol-induced,":[248],"ketorolac-induced,":[249],"ulcer).":[253],"study":[255],"also":[256],"demonstrated":[257],"exhibits":[264],"significant":[265],"anti-":[266],"vivo.":[273],"GRAPHICAL":[274],"ABSTRACT":[275]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-06-27T00:00:00"}