{"id":"https://openalex.org/W7165572931","doi":"https://doi.org/10.26434/chemrxiv.15005011/v1","title":"A Structural Model for Mononuclear Fe(II) Alkyl Persulfide Intermediates and its Sulfide Release Chemistry","display_name":"A Structural Model for Mononuclear Fe(II) Alkyl Persulfide Intermediates and its Sulfide Release Chemistry","publication_year":2026,"publication_date":"2026-06-22","ids":{"openalex":"https://openalex.org/W7165572931","doi":"https://doi.org/10.26434/chemrxiv.15005011/v1"},"language":"en","primary_location":{"id":"doi:10.26434/chemrxiv.15005011/v1","doi":"https://doi.org/10.26434/chemrxiv.15005011/v1","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv.15005011/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.26434/chemrxiv.15005011/v1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5139086259","display_name":"Keyan Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Keyan Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103119538","display_name":"Lev N. Zakharov","orcid":"https://orcid.org/0000-0003-3340-4645","observed_orcids":["https://orcid.org/0000-0003-3340-4645"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lev N. Zakharov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5085114228","display_name":"Michael D. Pluth","orcid":"https://orcid.org/0000-0003-3604-653X","observed_orcids":["https://orcid.org/0000-0003-3604-653X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael D. Pluth","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3604-653X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11626","display_name":"Metalloenzymes and iron-sulfur proteins","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/2105","display_name":"Renewable Energy, Sustainability and the Environment"},"field":{"id":"https://openalex.org/fields/21","display_name":"Energy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11626","display_name":"Metalloenzymes and iron-sulfur proteins","score":0.9286999702453613,"subfield":{"id":"https://openalex.org/subfields/2105","display_name":"Renewable Energy, Sustainability and the Environment"},"field":{"id":"https://openalex.org/fields/21","display_name":"Energy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10092","display_name":"Organometallic Complex Synthesis and Catalysis","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12557","display_name":"Inorganic Chemistry and Materials","score":0.010499999858438969,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iron-sulfur-cluster-assembly","display_name":"iron-sulfur cluster assembly","score":0.8289999961853027},{"id":"https://openalex.org/keywords/thiol-reduction","display_name":"thiol reduction","score":0.5400000214576721},{"id":"https://openalex.org/keywords/sulfide-metabolism","display_name":"sulfide metabolism","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8475000262260437},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.8093000054359436},{"id":"https://openalex.org/C40869318","wikidata":"https://www.wikidata.org/wiki/Q899050","display_name":"Synthon","level":2,"score":0.7685999870300293},{"id":"https://openalex.org/C2776910235","wikidata":"https://www.wikidata.org/wiki/Q18574","display_name":"Reactivity (psychology)","level":3,"score":0.6585000157356262},{"id":"https://openalex.org/C201194858","wikidata":"https://www.wikidata.org/wiki/Q898238","display_name":"Steric effects","level":2,"score":0.6481999754905701},{"id":"https://openalex.org/C2780596425","wikidata":"https://www.wikidata.org/wiki/Q221205","display_name":"Sulfide","level":2,"score":0.595300018787384},{"id":"https://openalex.org/C518881349","wikidata":"https://www.wikidata.org/wiki/Q682","display_name":"Sulfur","level":2,"score":0.43299999833106995},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.37400001287460327},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3720000088214874},{"id":"https://openalex.org/C2781324293","wikidata":"https://www.wikidata.org/wiki/Q220410","display_name":"Thiol","level":2,"score":0.34779998660087585},{"id":"https://openalex.org/C2777852564","wikidata":"https://www.wikidata.org/wiki/Q312085","display_name":"Iron\u2013sulfur cluster","level":3,"score":0.3407999873161316},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.313400000333786},{"id":"https://openalex.org/C114373084","wikidata":"https://www.wikidata.org/wiki/Q273499","display_name":"Chemical synthesis","level":3,"score":0.2678999900817871},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.2678000032901764},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.2563999891281128}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.26434/chemrxiv.15005011/v1","doi":"https://doi.org/10.26434/chemrxiv.15005011/v1","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv.15005011/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.26434/chemrxiv.15005011/v1","doi":"https://doi.org/10.26434/chemrxiv.15005011/v1","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv.15005011/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4400955933","https://openalex.org/W116612505","https://openalex.org/W7135015411","https://openalex.org/W2059919689","https://openalex.org/W2007135766","https://openalex.org/W2952261490","https://openalex.org/W2039165392","https://openalex.org/W2899426777","https://openalex.org/W4280489225","https://openalex.org/W2806217374"],"abstract_inverted_index":{"The":[0],"interactions":[1],"between":[2],"persulfides":[3,43],"(RSS":[4],"\u2013":[5],")":[6],"and":[7,14,22,37,50,62,93],"mononuclear":[8,39,68],"Fe":[9,40,69,103,129],"II":[10,41,70,104,130],"centers":[11],"pervade":[12],"biology":[13],"play":[15],"central":[16],"roles":[17],"in":[18,134],"both":[19],"sulfide":[20,121],"metabolism":[21],"the":[23,51,59,65,101,125],"assembly":[24,137],"of":[25,54,64,84,100],"ubiquitous":[26],"iron":[27],"sulfur":[28],"(Fe\u2013S)":[29],"clusters.":[30],"Despite":[31],"this":[32],"prevalence,":[33],"efforts":[34],"to":[35,120,124],"understand":[36],"characterize":[38],"alkyl":[42,71,90,131],"are":[44],"hampered":[45],"by":[46,80,107],"their":[47],"general":[48],"instability":[49],"synthetic":[52,67],"inaccessibility":[53],"persulfide":[55,72,91,132],"synthons.":[56],"We":[57],"report":[58],"synthesis,":[60],"characterization,":[61],"reactivity":[63,126],"first":[66],"species":[73],"with":[74],"a":[75,82,85,94,109],"biologically":[76],"relevant":[77],"coordination":[78],"environment":[79],"using":[81],"combination":[83],"sterically":[86,95],"hindered":[87],"contact-ion":[88],"stabilized":[89],"synthon":[92],"encumbered":[96],"FeII":[97],"precursor.":[98],"Reduction":[99],"isolated":[102],"-SSR":[105],"complex":[106],"either":[108],"thiol":[110],"(DTT)":[111],"or":[112],"outer":[113],"sphere":[114],"(Cp*":[115],"2":[116],"Co)":[117],"reductants":[118],"leads":[119],"release":[122],"akin":[123],"proposed":[127],"for":[128],"intermediates":[133],"Fe\u2013S":[135],"cluster":[136],"enzymes.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-06-23T00:00:00"}