{"id":"https://openalex.org/W7165534412","doi":"https://doi.org/10.1002/slct.73628","title":"Rapid and Highly Efficient Synthesis of O,O \u2010Dialkyl\u2010 N,N \u2010dialkylphosphoramidates From O,O \u2010Dialkylphosphites Using Iodine as a Catalyst via Atherton\u2013Todd Reaction","display_name":"Rapid and Highly Efficient Synthesis of O,O \u2010Dialkyl\u2010 N,N \u2010dialkylphosphoramidates From O,O \u2010Dialkylphosphites Using Iodine as a Catalyst via Atherton\u2013Todd Reaction","publication_year":2026,"publication_date":"2026-06-01","ids":{"openalex":"https://openalex.org/W7165534412","doi":"https://doi.org/10.1002/slct.73628"},"language":"en","primary_location":{"id":"doi:10.1002/slct.73628","doi":"https://doi.org/10.1002/slct.73628","is_oa":false,"landing_page_url":"https://doi.org/10.1002/slct.73628","pdf_url":null,"source":{"id":"https://openalex.org/S4210221416","display_name":"ChemistrySelect","issn_l":"2365-6549","issn":["2365-6549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemistrySelect","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5129409850","display_name":"Prince Malik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prince Malik","raw_affiliation_strings":["VERTOX Laboratory Defence Research and Development Establishment  Gwalior India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VERTOX Laboratory Defence Research and Development Establishment  Gwalior India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133765835","display_name":"Ajeet Kumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ajeet Kumar","raw_affiliation_strings":["VERTOX Laboratory Defence Research and Development Establishment  Gwalior India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VERTOX Laboratory Defence Research and Development Establishment  Gwalior India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067216752","display_name":"Meehir Palit","orcid":"https://orcid.org/0000-0003-0648-239X","observed_orcids":["https://orcid.org/0000-0003-0648-239X"]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Meehir Palit","raw_affiliation_strings":["VERTOX Laboratory Defence Research and Development Establishment  Gwalior India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VERTOX Laboratory Defence Research and Development Establishment  Gwalior India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008462857","display_name":"Ajay Kumar Purohit","orcid":"https://orcid.org/0000-0002-0771-4095","observed_orcids":["https://orcid.org/0000-0002-0771-4095"]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Ajay Kumar Purohit","raw_affiliation_strings":["VERTOX Laboratory Defence Research and Development Establishment  Gwalior India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VERTOX Laboratory Defence Research and Development Establishment  Gwalior India","institution_ids":["https://openalex.org/I2800900741"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5008462857"],"corresponding_institution_ids":["https://openalex.org/I2800900741"],"apc_list":{"value":3880,"currency":"USD","value_usd":3880},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35163042,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"24","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13239","display_name":"Phosphorus compounds and reactions","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12191","display_name":"Chemical Reaction Mechanisms","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atherton-todd-reaction","display_name":"Atherton-Todd reaction","score":0.8059999942779541},{"id":"https://openalex.org/keywords/molecular-iodine-catalysis","display_name":"iodine catalysis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/organophosphorus-synthesis","display_name":"organophosphorus synthesis","score":0.8270000219345093},{"id":"https://openalex.org/keywords/cesium-carbonate-base","display_name":"cesium carbonate base","score":0.718999981880188},{"id":"https://openalex.org/keywords/one-pot-synthesis","display_name":"one-pot synthesis","score":0.9440000057220459},{"id":"https://openalex.org/keywords/reference-materials","display_name":"reference materials","score":0.5809999704360962}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6187999844551086},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.5813999772071838},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.5573999881744385},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5386999845504761},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5248000025749207},{"id":"https://openalex.org/C539932907","wikidata":"https://www.wikidata.org/wiki/Q1103","display_name":"Iodine","level":2,"score":0.5153999924659729},{"id":"https://openalex.org/C2776130705","wikidata":"https://www.wikidata.org/wiki/Q143289","display_name":"Tabun","level":5,"score":0.5095999836921692},{"id":"https://openalex.org/C2778706303","wikidata":"https://www.wikidata.org/wiki/Q2612896","display_name":"Nerve agent","level":4,"score":0.5016999840736389},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.40869998931884766},{"id":"https://openalex.org/C114373084","wikidata":"https://www.wikidata.org/wiki/Q273499","display_name":"Chemical synthesis","level":3,"score":0.3910999894142151},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3707999885082245},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.328900009393692},{"id":"https://openalex.org/C88347474","wikidata":"https://www.wikidata.org/wiki/Q909003","display_name":"Fine chemical","level":3,"score":0.3239000141620636},{"id":"https://openalex.org/C2910751650","wikidata":"https://www.wikidata.org/wiki/Q3639228","display_name":"Chemical Warfare Agents","level":2,"score":0.31380000710487366},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.298799991607666},{"id":"https://openalex.org/C2991944050","wikidata":"https://www.wikidata.org/wiki/Q36534","display_name":"Reaction conditions","level":3,"score":0.28769999742507935},{"id":"https://openalex.org/C2776371256","wikidata":"https://www.wikidata.org/wiki/Q12370","display_name":"Salt (chemistry)","level":2,"score":0.28209999203681946},{"id":"https://openalex.org/C21880701","wikidata":"https://www.wikidata.org/wiki/Q2144042","display_name":"Process engineering","level":1,"score":0.26649999618530273},{"id":"https://openalex.org/C181886296","wikidata":"https://www.wikidata.org/wiki/Q903188","display_name":"Hydrogenolysis","level":3,"score":0.2574999928474426}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/slct.73628","doi":"https://doi.org/10.1002/slct.73628","is_oa":false,"landing_page_url":"https://doi.org/10.1002/slct.73628","pdf_url":null,"source":{"id":"https://openalex.org/S4210221416","display_name":"ChemistrySelect","issn_l":"2365-6549","issn":["2365-6549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemistrySelect","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W1968041420","https://openalex.org/W1981759797","https://openalex.org/W1985860963","https://openalex.org/W1995980076","https://openalex.org/W1996695698","https://openalex.org/W2007487132","https://openalex.org/W2008541712","https://openalex.org/W2028093584","https://openalex.org/W2028549532","https://openalex.org/W2029896069","https://openalex.org/W2038203130","https://openalex.org/W2092975717","https://openalex.org/W2116813348","https://openalex.org/W2129669628","https://openalex.org/W2131448320","https://openalex.org/W2143181858","https://openalex.org/W2145983349","https://openalex.org/W2157479369","https://openalex.org/W2165145085","https://openalex.org/W2272172892","https://openalex.org/W2332235088","https://openalex.org/W2335283609","https://openalex.org/W2463295065","https://openalex.org/W2469683089","https://openalex.org/W2606556915","https://openalex.org/W2800308219","https://openalex.org/W2871071696","https://openalex.org/W3023915741","https://openalex.org/W3048916138","https://openalex.org/W4212938704","https://openalex.org/W4246090912","https://openalex.org/W4308545203","https://openalex.org/W4309807652","https://openalex.org/W4390755459","https://openalex.org/W4396760568","https://openalex.org/W4406468441","https://openalex.org/W4409729087","https://openalex.org/W4410618201","https://openalex.org/W7118193261","https://openalex.org/W7134269758","https://openalex.org/W7136773146","https://openalex.org/W7138854965"],"related_works":[],"abstract_inverted_index":{"ABSTRACT":[0],"Phosphoramidates":[1],"constitute":[2],"a":[3,89,132,146,192],"fundamental":[4],"class":[5],"of":[6,43,49,65,100,179],"organophosphorus":[7,200],"compounds,":[8,185],"defined":[9],"by":[10],"their":[11,24],"distinctive":[12],"phosphorus\u2500nitrogen":[13],"(P\u2500N)":[14],"bond":[15],"and":[16,34,84,92,161,166,175,195,202],"highly":[17],"tunable":[18],"chemical":[19],"properties.":[20],"These":[21],"features":[22],"fortify":[23],"broad":[25],"utility":[26],"across":[27,171],"diverse":[28,173],"domains,":[29],"including":[30],"medicinal":[31],"chemistry,":[32],"agrochemicals,":[33],"advanced":[35],"materials.":[36],"Notably,":[37],"O,O":[38,101],"\u2010dialkyl\u2010":[39,102],"N,N":[40,103],"\u2010dialkylphosphoramidates":[41,104],"are":[42,57],"particular":[44],"significance":[45],"in":[46,121,145],"the":[47,66,73,98],"context":[48],"Chemical":[50],"Weapons":[51],"Convention":[52],"(CWC)":[53],"verification,":[54],"where":[55],"they":[56],"classified":[58],"under":[59],"Schedule":[60],"2.B.06":[61],"as":[62,117,131],"degradation":[63],"products":[64],"nerve":[67],"agent":[68],"Tabun":[69,187],"(GA).":[70],"To":[71],"address":[72],"limitations":[74],"associated":[75],"with":[76,123],"conventional":[77],"synthetic":[78,156],"routes\u2014often":[79],"reliant":[80],"on":[81],"toxic":[82],"reagents":[83],"harsh":[85],"reaction":[86],"conditions\u2014we":[87],"report":[88],"rapid,":[90],"efficient,":[91,194],"operationally":[93,196],"simple":[94,197],"one\u2010pot":[95],"protocol":[96],"for":[97,182,199],"synthesis":[99,201],"via":[105],"an":[106,118],"iodine\u2010catalyzed":[107],"Atherton\u2013Todd":[108],"reaction.":[109],"This":[110,154],"methodology":[111],"utilizes":[112],"inexpensive":[113],"iodine":[114],"(10":[115],"mol%)":[116],"efficient":[119],"catalyst":[120],"combination":[122],"cesium":[124],"carbonate":[125],"(Cs":[126],"2":[127],"CO":[128],"3":[129],")":[130],"base,":[133],"delivering":[134],"excellent":[135],"yields":[136],"(88%\u201395%)":[137],"within":[138],"just":[139],"20":[140],"min":[141],"at":[142],"ambient":[143],"temperature":[144],"CCl":[147],"4":[148],"/hexane":[149],"(1:4,":[150],"v/v)":[151],"solvent":[152],"system.":[153],"developed":[155],"method":[157],"eliminates":[158],"specialized":[159],"instrumentation":[160],"chromatographic":[162],"purification,":[163],"enhancing":[164],"practicality":[165],"scalability.":[167],"It":[168],"is":[169],"robust":[170],"10":[172],"derivatives":[174],"enables":[176],"reliable":[177],"preparation":[178],"reference":[180],"standards":[181],"identifying":[183],"CWC\u2010relevant":[184],"particularly":[186],"markers.":[188],"Overall,":[189],"it":[190],"offers":[191],"cost\u2010effective,":[193],"alternative":[198],"CWC":[203],"verification.":[204]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2026-06-23T00:00:00"}