{"id":"https://openalex.org/W7165017369","doi":"https://doi.org/10.1158/1541-7786.32708449","title":"Supplementary Figure 3 from Hepatitis B Virus X Protein Represses Expression of Tumor Suppressor PTPN18 in Hepatocellular Carcinoma","display_name":"Supplementary Figure 3 from Hepatitis B Virus X Protein Represses Expression of Tumor Suppressor PTPN18 in Hepatocellular Carcinoma","publication_year":2026,"publication_date":"2026-06-17","ids":{"openalex":"https://openalex.org/W7165017369","doi":"https://doi.org/10.1158/1541-7786.32708449"},"language":"en","primary_location":{"id":"doi:10.1158/1541-7786.32708449","doi":"https://doi.org/10.1158/1541-7786.32708449","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.32708449","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1541-7786.32708449","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082929705","display_name":"Zhenyu Zhou","orcid":"https://orcid.org/0000-0002-7934-4425","observed_orcids":["https://orcid.org/0000-0002-7934-4425"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhenyu Zhou","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7934-4425","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102929724","display_name":"Wei Yu","orcid":"https://orcid.org/0009-0005-8308-4231","observed_orcids":["https://orcid.org/0009-0005-8308-4231"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wei Yu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-8308-4231","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087967008","display_name":"Huoming Li","orcid":"https://orcid.org/0009-0007-0799-4043","observed_orcids":["https://orcid.org/0009-0007-0799-4043"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huoming Li","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-0799-4043","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064798052","display_name":"Juanyi Shi","orcid":"https://orcid.org/0009-0005-3967-0129","observed_orcids":["https://orcid.org/0009-0005-3967-0129"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juanyi Shi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-3967-0129","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044423636","display_name":"Shiyu Meng","orcid":"https://orcid.org/0009-0002-1670-3651","observed_orcids":["https://orcid.org/0009-0002-1670-3651"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shiyu Meng","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-1670-3651","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064314208","display_name":"Yongcong Yan","orcid":"https://orcid.org/0000-0002-7269-764X","observed_orcids":["https://orcid.org/0000-0002-7269-764X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yongcong Yan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7269-764X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019351540","display_name":"Ruibin Chen","orcid":"https://orcid.org/0009-0006-8983-5929","observed_orcids":["https://orcid.org/0009-0006-8983-5929"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ruibin Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-8983-5929","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079610982","display_name":"Haohan Liu","orcid":"https://orcid.org/0009-0001-9425-7119","observed_orcids":["https://orcid.org/0009-0001-9425-7119"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Haohan Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0001-9425-7119","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055288714","display_name":"Jie Wang","orcid":"https://orcid.org/0009-0000-4407-3461","observed_orcids":["https://orcid.org/0009-0000-4407-3461"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0000-4407-3461","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102999714","display_name":"Jian Sun","orcid":"https://orcid.org/0000-0001-5138-2289","observed_orcids":["https://orcid.org/0000-0001-5138-2289"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jian Sun","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5138-2289","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101619890","display_name":"Zhiyu Xiao","orcid":"https://orcid.org/0000-0002-2964-1552","observed_orcids":["https://orcid.org/0000-0002-2964-1552"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhiyu Xiao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2964-1552","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065697371","display_name":"Jianlong Zhang","orcid":"https://orcid.org/0000-0002-2288-7138","observed_orcids":["https://orcid.org/0000-0002-2288-7138"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jianlong Zhang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2288-7138","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.8842999935150146,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.8842999935150146,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.035599999129772186,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatitis-b-virus-x-protein","display_name":"hepatitis B virus X protein","score":0.8799999952316284},{"id":"https://openalex.org/keywords/tumor-suppressor-genes","display_name":"tumor suppressor","score":0.828000009059906},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hcclm3-cells","display_name":"HCCLM3 cells","score":0.746999979019165},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.670199990272522},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.6388000249862671},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6015999913215637},{"id":"https://openalex.org/C2780593183","wikidata":"https://www.wikidata.org/wiki/Q6844","display_name":"Hepatitis B virus","level":3,"score":0.5289999842643738},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.49939998984336853},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.49079999327659607},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.46540001034736633},{"id":"https://openalex.org/C2778264664","wikidata":"https://www.wikidata.org/wiki/Q422445","display_name":"Tumor suppressor gene","level":4,"score":0.4196000099182129},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3407000005245209},{"id":"https://openalex.org/C2780617729","wikidata":"https://www.wikidata.org/wiki/Q1356878","display_name":"Hepadnaviridae","level":4,"score":0.2809999883174896},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2786000072956085},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.2757999897003174},{"id":"https://openalex.org/C2777382497","wikidata":"https://www.wikidata.org/wiki/Q6853","display_name":"Hepatitis B","level":2,"score":0.2736999988555908},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.2678000032901764}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1541-7786.32708449","doi":"https://doi.org/10.1158/1541-7786.32708449","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.32708449","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/32708449","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Figure_3_from_Hepatitis_B_Virus_X_Protein_Represses_Expression_of_Tumor_Suppressor_PTPN18_in_Hepatocellular_Carcinoma/32708449","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1541-7786.32708449","doi":"https://doi.org/10.1158/1541-7786.32708449","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.32708449","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4398776686","https://openalex.org/W4402233658","https://openalex.org/W3091820625","https://openalex.org/W3141348285","https://openalex.org/W3088302881","https://openalex.org/W2294341854","https://openalex.org/W2337529533","https://openalex.org/W2991128656","https://openalex.org/W1841699403","https://openalex.org/W2365231899"],"abstract_inverted_index":{"PTPN18":[0],"overexpression":[1],"promotes":[2],"HCCLM3":[3],"migration":[4],"and":[5],"proliferation.":[6]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-06-18T00:00:00"}