{"id":"https://openalex.org/W7164011908","doi":"https://doi.org/10.1093/skinhd/vzag062","title":"ALADIN (Acne Lesion And Density INdex): a novel tool for automatic acne severity assessment","display_name":"ALADIN (Acne Lesion And Density INdex): a novel tool for automatic acne severity assessment","publication_year":2026,"publication_date":"2026-04-08","ids":{"openalex":"https://openalex.org/W7164011908","doi":"https://doi.org/10.1093/skinhd/vzag062","pmid":"https://pubmed.ncbi.nlm.nih.gov/42539975","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13425072"},"language":"en","primary_location":{"id":"doi:10.1093/skinhd/vzag062","doi":"https://doi.org/10.1093/skinhd/vzag062","is_oa":true,"landing_page_url":"https://doi.org/10.1093/skinhd/vzag062","pdf_url":null,"source":{"id":"https://openalex.org/S4210233137","display_name":"Skin Health and Disease","issn_l":"2690-442X","issn":["2690-442X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skin Health and Disease","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/skinhd/vzag062","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048242893","display_name":"Alfonso Medela","orcid":"https://orcid.org/0000-0001-5859-5439","observed_orcids":["https://orcid.org/0000-0001-5859-5439"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Alfonso Medela","raw_affiliation_strings":["Department of Medical Data Science, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Data Science, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078499486","display_name":"Alberto Sabater","orcid":"https://orcid.org/0000-0002-1156-8617","observed_orcids":["https://orcid.org/0000-0002-1156-8617"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alberto Sabater","raw_affiliation_strings":["Department of Medical Data Science, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Data Science, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030340322","display_name":"Ignacio Hern\u00e1ndez Montilla","orcid":"https://orcid.org/0000-0003-0356-6619","observed_orcids":["https://orcid.org/0000-0003-0356-6619"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ignacio Hern\u00e1ndez Montilla","raw_affiliation_strings":["Department of Medical Data Science, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Data Science, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039107242","display_name":"Taig Mac Carthy","orcid":"https://orcid.org/0000-0001-5583-5273","observed_orcids":["https://orcid.org/0000-0001-5583-5273"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Taig Mac Carthy","raw_affiliation_strings":["Department of Clinical Endpoint Innovation, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Endpoint Innovation, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052920775","display_name":"Andy Aguilar","orcid":"https://orcid.org/0000-0003-0618-6179","observed_orcids":["https://orcid.org/0000-0003-0618-6179"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andy Aguilar","raw_affiliation_strings":["Department of Clinical Endpoint Innovation, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Endpoint Innovation, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120960642","display_name":"Gerardo Fern\u00e1ndez","orcid":"https://orcid.org/0009-0006-9721-9974","observed_orcids":["https://orcid.org/0009-0006-9721-9974"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerardo Fern\u00e1ndez","raw_affiliation_strings":["Department of Medical Data Science, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Data Science, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043946186","display_name":"Antonio Martorell","orcid":"https://orcid.org/0000-0003-1378-1590","observed_orcids":["https://orcid.org/0000-0003-1378-1590"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antonio Martorell","raw_affiliation_strings":["Department of Clinical Endpoint Innovation, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Endpoint Innovation, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138286674","display_name":"Sofia Vera Carretero","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sofia Vera Carretero","raw_affiliation_strings":["Department of Medical Data Science, Legit.Health , Bilbao ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Data Science, Legit.Health , Bilbao ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012413293","display_name":"Constanza Balboni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101151","display_name":"Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n","ror":"https://ror.org/01435q086","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210101151","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Constanza Balboni","raw_affiliation_strings":["Department of Dermatology, DermoMedic Center, Hospital Universitario Fundaci\u00f3n de Alcorc\u00f3n , Madrid ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, DermoMedic Center, Hospital Universitario Fundaci\u00f3n de Alcorc\u00f3n , Madrid ,","institution_ids":["https://openalex.org/I4210101151"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032301482","display_name":"Javier Mart\u00edn\u2010Alcalde","orcid":"https://orcid.org/0000-0002-9574-5421","observed_orcids":["https://orcid.org/0000-0002-9574-5421"]},"institutions":[{"id":"https://openalex.org/I4210101151","display_name":"Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n","ror":"https://ror.org/01435q086","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210101151","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Mart\u00edn Alcalde","raw_affiliation_strings":["Department of Dermatology, DermoMedic Center, Hospital Universitario Fundaci\u00f3n de Alcorc\u00f3n , Madrid ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, DermoMedic Center, Hospital Universitario Fundaci\u00f3n de Alcorc\u00f3n , Madrid ,","institution_ids":["https://openalex.org/I4210101151"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061121020","display_name":"Jos\u00e9 Luis Ram\u00edrez-Bellver","orcid":"https://orcid.org/0000-0001-7954-9335","observed_orcids":["https://orcid.org/0000-0001-7954-9335"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jose Luis Ram\u00edrez Bellver","raw_affiliation_strings":["Dermatology Department, Instituto M\u00e9dico Ricart , Madrid ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dermatology Department, Instituto M\u00e9dico Ricart , Madrid ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004797265","display_name":"Alejandro Mart\u00edn-Gorgojo","orcid":"https://orcid.org/0000-0002-0589-5718","observed_orcids":["https://orcid.org/0000-0002-0589-5718"]},"institutions":[{"id":"https://openalex.org/I4210139293","display_name":"Comunidad de Madrid","ror":"https://ror.org/040scgh75","country_code":"ES","type":"government","lineage":["https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alejandro Martin-Gorgojo","raw_affiliation_strings":["STI/Dermatology Department, Madrid City Council , Madrid ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"STI/Dermatology Department, Madrid City Council , Madrid ,","institution_ids":["https://openalex.org/I4210139293"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138265653","display_name":"Pedro Rodriguez Jim\u00e9nez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130498","display_name":"Hospital Universitario de La Princesa","ror":"https://ror.org/03cg5md32","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210130498","https://openalex.org/I4210139293"]},{"id":"https://openalex.org/I4210150844","display_name":"Hospital Ruber Internacional","ror":"https://ror.org/04abjq359","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210150844"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pedro Rodriguez Jim\u00e9nez","raw_affiliation_strings":["Department of Dermatology, Hospital Universitario de la Princesa, Hospital Ruber Internacional , Madrid ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Hospital Universitario de la Princesa, Hospital Ruber Internacional , Madrid ,","institution_ids":["https://openalex.org/I4210130498","https://openalex.org/I4210150844"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5130248417","display_name":"Jos\u00e9 Luis L\u00f3pez Estebaranz","orcid":"https://orcid.org/0000-0002-8816-1989","observed_orcids":["https://orcid.org/0000-0002-8816-1989"]},"institutions":[{"id":"https://openalex.org/I4210101151","display_name":"Hospital Universitario Fundaci\u00f3n Alcorc\u00f3n","ror":"https://ror.org/01435q086","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210101151","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jose Luis L\u00f3pez Estebaranz","raw_affiliation_strings":["Department of Dermatology, DermoMedic Center, Hospital Universitario Fundaci\u00f3n de Alcorc\u00f3n , Madrid ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, DermoMedic Center, Hospital Universitario Fundaci\u00f3n de Alcorc\u00f3n , Madrid ,","institution_ids":["https://openalex.org/I4210101151"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5048242893"],"corresponding_institution_ids":[],"apc_list":{"value":1969,"currency":"GBP","value_usd":2597},"apc_paid":{"value":1969,"currency":"GBP","value_usd":2597},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36532661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"4","first_page":"503","last_page":"510"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11553","display_name":"Acne and Rosacea Treatments and Effects","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11553","display_name":"Acne and Rosacea Treatments and Effects","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11448","display_name":"Face recognition and analysis","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acne-severity-assessment","display_name":"acne severity assessment","score":0.890999972820282},{"id":"https://openalex.org/keywords/aladin","display_name":"ALADIN","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lesion-detection","display_name":"lesion detection","score":0.5419999957084656},{"id":"https://openalex.org/keywords/investigator-s-global-assessment","display_name":"Investigator's Global Assessment","score":0.8550000190734863},{"id":"https://openalex.org/keywords/global-acne-grading-system","display_name":"Global Acne Grading System","score":0.9940000176429749},{"id":"https://openalex.org/keywords/facial-image-analysis","display_name":"facial image analysis","score":0.6340000033378601},{"id":"https://openalex.org/keywords/observer-variability","display_name":"observer variability","score":0.7039999961853027},{"id":"https://openalex.org/keywords/medical-device-software","display_name":"medical device software","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C2777673923","wikidata":"https://www.wikidata.org/wiki/Q79928","display_name":"Acne","level":2,"score":0.8248999714851379},{"id":"https://openalex.org/C2777286243","wikidata":"https://www.wikidata.org/wiki/Q5591926","display_name":"Grading (engineering)","level":2,"score":0.7110999822616577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6277999877929688},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.6110000014305115},{"id":"https://openalex.org/C188087704","wikidata":"https://www.wikidata.org/wiki/Q369577","display_name":"Standardization","level":2,"score":0.4456000030040741},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.36169999837875366},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35659998655319214},{"id":"https://openalex.org/C3020132585","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic accuracy","level":2,"score":0.34220001101493835},{"id":"https://openalex.org/C2984588014","wikidata":"https://www.wikidata.org/wiki/Q730675","display_name":"Quantitative assessment","level":2,"score":0.3328999876976013},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3131999969482422},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.30379998683929443},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2892000079154968},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.25380000472068787}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/skinhd/vzag062","doi":"https://doi.org/10.1093/skinhd/vzag062","is_oa":true,"landing_page_url":"https://doi.org/10.1093/skinhd/vzag062","pdf_url":null,"source":{"id":"https://openalex.org/S4210233137","display_name":"Skin Health and Disease","issn_l":"2690-442X","issn":["2690-442X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skin Health and Disease","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13425072","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13425072/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13425072/pdf/vzag062.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skin Health Dis","raw_type":"Text"},{"id":"pmid:42539975","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42539975","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skin health and disease","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/skinhd/vzag062","doi":"https://doi.org/10.1093/skinhd/vzag062","is_oa":true,"landing_page_url":"https://doi.org/10.1093/skinhd/vzag062","pdf_url":null,"source":{"id":"https://openalex.org/S4210233137","display_name":"Skin Health and Disease","issn_l":"2690-442X","issn":["2690-442X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skin Health and Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321043","display_name":"Centro para el Desarrollo Tecnol\u00f3gico Industrial","ror":"https://ror.org/0124x7055"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W34446656","https://openalex.org/W1595159159","https://openalex.org/W1971883262","https://openalex.org/W1985243166","https://openalex.org/W3003257820","https://openalex.org/W3014713696","https://openalex.org/W3035041022","https://openalex.org/W3088445321","https://openalex.org/W4242549290","https://openalex.org/W4327575282","https://openalex.org/W4380208012"],"related_works":["https://openalex.org/W4411732562","https://openalex.org/W2969525510","https://openalex.org/W4403089499","https://openalex.org/W6980030002","https://openalex.org/W2977323083","https://openalex.org/W4387403350","https://openalex.org/W4406120202","https://openalex.org/W4386040715","https://openalex.org/W4376114679","https://openalex.org/W4403218022"],"abstract_inverted_index":{"Background:":[0],"Acne":[1,134,161],"affects":[2],"approximately":[3],"80%":[4],"of":[5,9,26,116,123,181,186,233],"adolescents":[6],"worldwide,":[7],"regardless":[8],"age,":[10],"sex":[11],"or":[12],"ethnicity.":[13],"Effective":[14],"treatment":[15],"depends":[16],"on":[17],"timely":[18],"and":[19,33,38,62,96,118,132,156,170,190,195,202,206,218,253,268,275],"accurate":[20],"severity":[21,48,99,251],"assessment.":[22],"However,":[23,257],"the":[24,72,178],"lack":[25],"methodological":[27],"standardization":[28],"results":[29,127],"in":[30,248,258],"high":[31],"inter-":[32],"intraobserver":[34],"variability.":[35],"A":[36],"standardized":[37],"explainable":[39],"grading":[40,162],"tool":[41,56],"is":[42,85],"needed":[43],"to":[44,67,93],"support":[45],"consistent":[46,216],"acne":[47,98,117,250],"evaluation.":[49],"Objectives:":[50],"To":[51],"develop":[52],"an":[53],"artificial":[54],"intelligence-driven":[55],"that":[57],"quantifies":[58],"inflammatory":[59],"lesion":[60],"count":[61],"density":[63],"from":[64],"facial":[65],"images":[66],"calculate":[68],"scores":[69],"aligned":[70,175],"with":[71,112,146,177,222,266,278],"Investigator":[73],"Global":[74,133],"Assessment":[75],"(IGA)":[76],"scale.":[77],"Methods:":[78],"ALADIN":[79,103,129,147,214],"(Acne":[80],"Lesion":[81,144],"And":[82],"Density":[83],"INdex)":[84],"designed":[86],"as":[87],"a":[88,109,120,228,240],"simple":[89],"mathematical":[90],"model":[91],"able":[92],"deliver":[94],"reproducible":[95],"interpretable":[97],"scores.":[100,212],"We":[101],"validated":[102],"retrospectively":[104],"using":[105,150],"two":[106],"datasets:":[107],"(i)":[108],"public":[110,196],"dataset":[111,122],"predominantly":[113],"severe":[114],"cases":[115],"(ii)":[119],"private":[121],"mild-to-moderate":[124],"cases.":[125],"Validation":[126],"evaluated":[128,149],"against":[130],"IGA":[131,200],"Grading":[135],"System":[136],"(GAGS)":[137],"scores,":[138,201],"annotated":[139],"by":[140],"expert":[141],"dermatologists.":[142],"Results:":[143],"detection":[145],"was":[148,164],"precision,":[151],"recall,":[152],"mean":[153,157],"average":[154],"precision":[155],"absolute":[158],"error":[159],"(MAE).":[160],"performance":[163,174,217],"assessed":[165],"via":[166],"Pearson/Spearman":[167],"correlations,":[168],"MAE":[169],"Cohen's":[171],"kappa.":[172],"ALADIN's":[173],"well":[176],"interobserver":[179],"correlation":[180],"dermatologists,":[182],"achieving":[183],"Pearson":[184],"correlations":[185],"0.58":[187],"vs.":[188,192,204,208],"0.56":[189],"0.65":[191,193],"(private":[194],"datasets,":[197],"respectively)":[198],"for":[199,210],"0.32":[203],"0.44":[205,209],"0.43":[207],"GAGS":[211],"Conclusions:":[213],"demonstrates":[215],"excellent":[219],"interpretability.":[220],"Compared":[221],"manual":[223],"scoring":[224],"systems,":[225],"it":[226,244],"provides":[227],"streamlined,":[229],"data-driven":[230],"alternative":[231],"capable":[232],"minimizing":[234],"observer":[235],"bias.":[236],"When":[237],"integrated":[238],"into":[239],"medical":[241],"device":[242],"software,":[243],"can":[245],"further":[246],"aid":[247],"standardizing":[249],"assessment":[252],"enhance":[254],"patient":[255],"monitoring.":[256],"this":[259],"study,":[260],"analyses":[261],"were":[262],"predominately":[263],"carried":[264],"out":[265],"White":[267],"Asian":[269],"patients.":[270],"Future":[271],"work":[272],"will":[273],"validate":[274],"ensure":[276],"robustness":[277],"darker":[279],"skin":[280],"tones.":[281]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-06-10T00:00:00"}