{"id":"https://openalex.org/W7163744643","doi":"https://doi.org/10.1016/j.rmed.2026.108939","title":"The clinical efficacy of hydrogen combined with tetrandrine in the treatment of silicosis fibrosis: A randomized controlled intervention study","display_name":"The clinical efficacy of hydrogen combined with tetrandrine in the treatment of silicosis fibrosis: A randomized controlled intervention study","publication_year":2026,"publication_date":"2026-06-06","ids":{"openalex":"https://openalex.org/W7163744643","doi":"https://doi.org/10.1016/j.rmed.2026.108939","pmid":"https://pubmed.ncbi.nlm.nih.gov/42250702"},"language":"en","primary_location":{"id":"doi:10.1016/j.rmed.2026.108939","doi":"https://doi.org/10.1016/j.rmed.2026.108939","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.rmed.2026.108939","pdf_url":null,"source":{"id":"https://openalex.org/S71995303","display_name":"Respiratory Medicine","issn_l":"0954-6111","issn":["0954-6111","1532-3064"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5138046932","display_name":"Kang Xiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161716053","display_name":"China Pharmaceutical University","ror":"https://ror.org/01sfm2718","country_code":"CN","type":"education","lineage":["https://openalex.org/I161716053"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kang Xiao","raw_affiliation_strings":["School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211100, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211100, PR China","institution_ids":["https://openalex.org/I161716053"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yanping Sang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yanping Sang","raw_affiliation_strings":["Occupational Disease Department, Lai Zhou City Chronic Disease Prevention and Treatment Hospital, Laizhou City, Shandong Province, 261400, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Occupational Disease Department, Lai Zhou City Chronic Disease Prevention and Treatment Hospital, Laizhou City, Shandong Province, 261400, PR China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111343978","display_name":"Mao Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mao Cao","raw_affiliation_strings":["Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China","institution_ids":["https://openalex.org/I4210163399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000074603","display_name":"Yi Yang","orcid":"https://orcid.org/0000-0002-4091-8532","observed_orcids":["https://orcid.org/0000-0002-4091-8532","https://orcid.org/0000-0003-3703-2527","https://orcid.org/0000-0002-4225-5226","https://orcid.org/0000-0001-9467-0942","https://orcid.org/0000-0002-4310-1966","https://orcid.org/0000-0001-6180-676X","https://orcid.org/0000-0002-1438-9307","https://orcid.org/0000-0002-4040-2448","https://orcid.org/0000-0002-5662-4600","https://orcid.org/0000-0002-6287-1640","https://orcid.org/0000-0002-6636-8831","https://orcid.org/0000-0003-1015-8998","https://orcid.org/0000-0003-2089-186X","https://orcid.org/0000-0001-9386-5027","https://orcid.org/0000-0002-0754-935X","https://orcid.org/0000-0002-0947-3475","https://orcid.org/0000-0002-1364-8653","https://orcid.org/0000-0002-3144-8604","https://orcid.org/0000-0002-5276-4518","https://orcid.org/0000-0002-5598-6925","https://orcid.org/0000-0002-6134-6094","https://orcid.org/0000-0002-6972-8708","https://orcid.org/0000-0002-7825-0494","https://orcid.org/0000-0002-8209-2898","https://orcid.org/0000-0003-1048-7994","https://orcid.org/0000-0003-3964-2433","https://orcid.org/0000-0003-4431-2279","https://orcid.org/0000-0003-4674-4059","https://orcid.org/0009-0000-6572-6898","https://orcid.org/0009-0000-7907-9388","https://orcid.org/0009-0001-5752-0264","https://orcid.org/0009-0006-3953-305X","https://orcid.org/0009-0007-6119-6034","https://orcid.org/0009-0008-1843-5519","https://orcid.org/0000-0001-5065-2769","https://orcid.org/0000-0001-5604-5505","https://orcid.org/0000-0001-5988-1998","https://orcid.org/0000-0001-6051-4992","https://orcid.org/0000-0001-6489-286X","https://orcid.org/0000-0001-6682-6006","https://orcid.org/0000-0001-6772-5776","https://orcid.org/0000-0001-6868-5438","https://orcid.org/0000-0001-8495-6103","https://orcid.org/0000-0001-8623-0453","https://orcid.org/0000-0001-8687-4427","https://orcid.org/0000-0001-8785-2692","https://orcid.org/0000-0001-9807-6844","https://orcid.org/0000-0002-0005-7619","https://orcid.org/0000-0002-0130-9785","https://orcid.org/0000-0002-0491-8295","https://orcid.org/0000-0002-0815-2776","https://orcid.org/0000-0002-0864-9029","https://orcid.org/0000-0002-1488-4762","https://orcid.org/0000-0002-1490-6802","https://orcid.org/0000-0002-2135-5076","https://orcid.org/0000-0002-2971-7828","https://orcid.org/0000-0002-3362-7155","https://orcid.org/0000-0002-3530-3525","https://orcid.org/0000-0002-3537-1253","https://orcid.org/0000-0002-3860-8463","https://orcid.org/0000-0002-3872-5336","https://orcid.org/0000-0002-3931-4096","https://orcid.org/0000-0002-3968-7992","https://orcid.org/0000-0002-4186-3799","https://orcid.org/0000-0002-4495-0636","https://orcid.org/0000-0002-4573-9437","https://orcid.org/0000-0002-5070-4511","https://orcid.org/0000-0002-5241-5203","https://orcid.org/0000-0002-6278-4061","https://orcid.org/0000-0002-6489-4459","https://orcid.org/0000-0002-6561-9109","https://orcid.org/0000-0002-7132-5860","https://orcid.org/0000-0002-7378-8260","https://orcid.org/0000-0002-7540-892X","https://orcid.org/0000-0002-7669-768X","https://orcid.org/0000-0002-7680-1731","https://orcid.org/0000-0002-8071-629X","https://orcid.org/0000-0002-9266-8600","https://orcid.org/0000-0002-9477-2313","https://orcid.org/0000-0002-9609-6865","https://orcid.org/0000-0002-9799-3293","https://orcid.org/0000-0002-9831-8783","https://orcid.org/0000-0003-0566-4802","https://orcid.org/0000-0003-0633-8355","https://orcid.org/0000-0003-1033-8737","https://orcid.org/0000-0003-1995-7219","https://orcid.org/0000-0003-2266-6682","https://orcid.org/0000-0003-3526-560X","https://orcid.org/0000-0003-3689-6964","https://orcid.org/0000-0003-4250-3805","https://orcid.org/0000-0003-4271-3554","https://orcid.org/0009-0000-0235-1371","https://orcid.org/0009-0000-2097-9373","https://orcid.org/0009-0000-2610-7680","https://orcid.org/0009-0000-3730-6861","https://orcid.org/0009-0000-4637-4639","https://orcid.org/0009-0000-5296-5523","https://orcid.org/0009-0000-6509-5694","https://orcid.org/0009-0000-7131-1832","https://orcid.org/0009-0000-8564-9228","https://orcid.org/0009-0001-0338-8528","https://orcid.org/0009-0001-0383-126X","https://orcid.org/0009-0001-0703-8445","https://orcid.org/0009-0001-1212-3660","https://orcid.org/0009-0001-2852-6608","https://orcid.org/0009-0001-3206-6667","https://orcid.org/0009-0001-4443-0243","https://orcid.org/0009-0001-6723-4456","https://orcid.org/0009-0001-7156-743X","https://orcid.org/0009-0001-8004-8703","https://orcid.org/0009-0002-0806-4087","https://orcid.org/0009-0002-1771-3763","https://orcid.org/0009-0002-2959-4095","https://orcid.org/0009-0002-3110-8594","https://orcid.org/0009-0002-3999-0569","https://orcid.org/0009-0002-4946-5813","https://orcid.org/0009-0002-5125-5014","https://orcid.org/0009-0002-6785-8485","https://orcid.org/0009-0002-7667-6632","https://orcid.org/0009-0002-7856-1804","https://orcid.org/0009-0002-9567-1263","https://orcid.org/0009-0003-0192-6112","https://orcid.org/0009-0003-1350-7767","https://orcid.org/0009-0003-2133-4691","https://orcid.org/0009-0003-3358-4495","https://orcid.org/0009-0003-3395-2059","https://orcid.org/0009-0003-4252-2288","https://orcid.org/0009-0003-5606-5954","https://orcid.org/0009-0003-6026-0226","https://orcid.org/0009-0003-6306-9611","https://orcid.org/0009-0003-7714-0060","https://orcid.org/0009-0003-9738-4484","https://orcid.org/0009-0004-0953-5631","https://orcid.org/0009-0004-2597-460X","https://orcid.org/0009-0004-3989-5507","https://orcid.org/0009-0004-4464-6396","https://orcid.org/0009-0004-6178-6294","https://orcid.org/0009-0004-6249-7152","https://orcid.org/0009-0004-6732-8104","https://orcid.org/0009-0004-7233-8227","https://orcid.org/0009-0005-1496-9183","https://orcid.org/0009-0005-2539-6851","https://orcid.org/0009-0005-3453-9842","https://orcid.org/0009-0005-4380-9808","https://orcid.org/0009-0005-4913-5904","https://orcid.org/0009-0005-4922-8502","https://orcid.org/0009-0005-6609-3371","https://orcid.org/0009-0005-7123-9056","https://orcid.org/0009-0006-0540-4938","https://orcid.org/0009-0006-1342-3020","https://orcid.org/0009-0006-1836-0823","https://orcid.org/0009-0006-5733-8258","https://orcid.org/0009-0006-7931-8661","https://orcid.org/0009-0006-9458-9267","https://orcid.org/0009-0006-9629-7639","https://orcid.org/0009-0007-0195-0816","https://orcid.org/0009-0007-1120-2045","https://orcid.org/0009-0007-1342-272X","https://orcid.org/0009-0007-3011-530X","https://orcid.org/0009-0007-3259-798X","https://orcid.org/0009-0007-5621-8219","https://orcid.org/0009-0007-5894-4724","https://orcid.org/0009-0007-6270-7086","https://orcid.org/0009-0007-9873-799X","https://orcid.org/0009-0008-1257-9933","https://orcid.org/0009-0008-2210-3664","https://orcid.org/0009-0008-2458-4932","https://orcid.org/0009-0008-3637-7922","https://orcid.org/0009-0008-3789-3136","https://orcid.org/0009-0008-4576-9477","https://orcid.org/0009-0008-4640-5333","https://orcid.org/0009-0008-9069-1162","https://orcid.org/0009-0008-9817-1612","https://orcid.org/0009-0009-0547-0873","https://orcid.org/0009-0009-0688-5966","https://orcid.org/0009-0009-1012-801X","https://orcid.org/0009-0009-1925-9518","https://orcid.org/0009-0009-2931-9246","https://orcid.org/0009-0009-3980-9564","https://orcid.org/0009-0009-4389-583X","https://orcid.org/0009-0009-6469-9053","https://orcid.org/0009-0009-6668-2554","https://orcid.org/0009-0009-6915-6912","https://orcid.org/0009-0009-8140-7710","https://orcid.org/0009-0009-9094-6046"]},"institutions":[{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Yang","raw_affiliation_strings":["Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China","institution_ids":["https://openalex.org/I4210163399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019120280","display_name":"Mengjie Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengjie Cheng","raw_affiliation_strings":["Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China","institution_ids":["https://openalex.org/I4210163399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115597813","display_name":"Jiazi Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiazi Ma","raw_affiliation_strings":["Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China","institution_ids":["https://openalex.org/I4210163399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100420061","display_name":"Siqi Wang","orcid":"https://orcid.org/0000-0001-6136-2492","observed_orcids":["https://orcid.org/0000-0001-6136-2492","https://orcid.org/0009-0006-0430-5540","https://orcid.org/0009-0007-0277-3268","https://orcid.org/0000-0002-8594-3766"]},"institutions":[{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siqi Wang","raw_affiliation_strings":["Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China","institution_ids":["https://openalex.org/I4210163399"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138067312","display_name":"Xinyue Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyue Li","raw_affiliation_strings":["School of Public Health, Jilin University, Changchun City, Jilin Province, 130021, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, Jilin University, Changchun City, Jilin Province, 130021, PR China","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054294994","display_name":"\u4e01\u9009\u80dc","orcid":"https://orcid.org/0009-0007-4746-8291","observed_orcids":["https://orcid.org/0009-0007-4746-8291"]},"institutions":[{"id":"https://openalex.org/I161716053","display_name":"China Pharmaceutical University","ror":"https://ror.org/01sfm2718","country_code":"CN","type":"education","lineage":["https://openalex.org/I161716053"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xuansheng Ding","raw_affiliation_strings":["School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211100, PR China. Electronic address: dinhsdxuansheng@outlook.com"],"raw_orcid":"https://orcid.org/0009-0007-4746-8291","affiliations":[{"raw_affiliation_string":"School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu Province, 211100, PR China. Electronic address: dinhsdxuansheng@outlook.com","institution_ids":["https://openalex.org/I161716053"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5126816857","display_name":"Z J Du","orcid":"https://orcid.org/0000-0001-7422-6035","observed_orcids":["https://orcid.org/0000-0001-7422-6035"]},"institutions":[{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongjun Du","raw_affiliation_strings":["Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China; Department of Occupational Disease, Harbin Second Hospital, Harbin City, Heilongjiang Province, 150026, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan City, Shandong Province, 250062, PR China; Department of Occupational Disease, Harbin Second Hospital, Harbin City, Heilongjiang Province, 150026, PR China","institution_ids":["https://openalex.org/I4210163399"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5054294994"],"corresponding_institution_ids":["https://openalex.org/I161716053"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.40526368,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"260","issue":null,"first_page":"108939","last_page":"108939"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13775","display_name":"Hydrogen's biological and therapeutic effects","score":0.8184000253677368,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13775","display_name":"Hydrogen's biological and therapeutic effects","score":0.8184000253677368,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.11110000312328339,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.035599999129772186,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silicosis","display_name":"silicosis","score":0.9160000085830688},{"id":"https://openalex.org/keywords/hydrogen-inhalation","display_name":"hydrogen inhalation","score":0.7620000243186951},{"id":"https://openalex.org/keywords/tetrandrine","display_name":"tetrandrine","score":0.996999979019165},{"id":"https://openalex.org/keywords/pulmonary-fibrosis","display_name":"pulmonary fibrosis","score":0.8610000014305115},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.9300000071525574},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8550000190734863},{"id":"https://openalex.org/keywords/diffusing-capacity-for-carbon-monoxide","display_name":"diffusing capacity for carbon monoxide","score":0.9279999732971191},{"id":"https://openalex.org/keywords/lung-function","display_name":"lung function","score":0.9160000085830688},{"id":"https://openalex.org/keywords/dyspnea","display_name":"dyspnea","score":0.8759999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9711999893188477},{"id":"https://openalex.org/C2779934757","wikidata":"https://www.wikidata.org/wiki/Q7706612","display_name":"Tetrandrine","level":2,"score":0.7271000146865845},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5961999893188477},{"id":"https://openalex.org/C2777811718","wikidata":"https://www.wikidata.org/wiki/Q653318","display_name":"Silicosis","level":2,"score":0.5825999975204468},{"id":"https://openalex.org/C165637977","wikidata":"https://www.wikidata.org/wiki/Q11067835","display_name":"Diffusing capacity","level":4,"score":0.5013999938964844},{"id":"https://openalex.org/C2776999253","wikidata":"https://www.wikidata.org/wiki/Q1304270","display_name":"Combination therapy","level":2,"score":0.4702000021934509},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.46380001306533813},{"id":"https://openalex.org/C2780333948","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Spirometry","level":3,"score":0.42100000381469727},{"id":"https://openalex.org/C2776954882","wikidata":"https://www.wikidata.org/wiki/Q840343","display_name":"Inhalation","level":2,"score":0.41830000281333923},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.3790999948978424},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.3224000036716461},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.31529998779296875},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.31459999084472656},{"id":"https://openalex.org/C55520419","wikidata":"https://www.wikidata.org/wiki/Q660995","display_name":"Vital capacity","level":5,"score":0.31220000982284546},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.3077000081539154},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.2987000048160553},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.27810001373291016},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2732999920845032},{"id":"https://openalex.org/C102652120","wikidata":"https://www.wikidata.org/wiki/Q2419430","display_name":"Therapeutic effect","level":2,"score":0.2728999853134155},{"id":"https://openalex.org/C2777543607","wikidata":"https://www.wikidata.org/wiki/Q1153419","display_name":"Interstitial lung disease","level":3,"score":0.26829999685287476},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.2581000030040741},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.25459998846054077}],"mesh":[{"descriptor_ui":"D000280","descriptor_name":"Administration, Inhalation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006859","descriptor_name":"Hydrogen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006859","descriptor_name":"Hydrogen","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012129","descriptor_name":"Respiratory Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012829","descriptor_name":"Silicosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012829","descriptor_name":"Silicosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044182","descriptor_name":"Benzylisoquinolines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D044182","descriptor_name":"Benzylisoquinolines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.rmed.2026.108939","doi":"https://doi.org/10.1016/j.rmed.2026.108939","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.rmed.2026.108939","pdf_url":null,"source":{"id":"https://openalex.org/S71995303","display_name":"Respiratory Medicine","issn_l":"0954-6111","issn":["0954-6111","1532-3064"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory Medicine","raw_type":"journal-article"},{"id":"pmid:42250702","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42250702","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Respiratory medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W2005312855","https://openalex.org/W2005369618","https://openalex.org/W2068173118","https://openalex.org/W2096411361","https://openalex.org/W2157968241","https://openalex.org/W2173131152","https://openalex.org/W2583406037","https://openalex.org/W2590602992","https://openalex.org/W2591079195","https://openalex.org/W2909196928","https://openalex.org/W3048609107","https://openalex.org/W3084663868","https://openalex.org/W3115762959","https://openalex.org/W3161718576","https://openalex.org/W3207669271","https://openalex.org/W4295008801","https://openalex.org/W4321242142","https://openalex.org/W4385707288","https://openalex.org/W4389056287","https://openalex.org/W4389513540","https://openalex.org/W4400150433","https://openalex.org/W4400677467","https://openalex.org/W4412522395"],"related_works":["https://openalex.org/W2971234639","https://openalex.org/W2412111333","https://openalex.org/W3034978468","https://openalex.org/W7118166185","https://openalex.org/W2372883480","https://openalex.org/W2999616705","https://openalex.org/W3030728207","https://openalex.org/W3035175684","https://openalex.org/W4321241672","https://openalex.org/W4412522395"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2026-06-07T00:00:00"}