{"id":"https://openalex.org/W7163402687","doi":"https://doi.org/10.17605/osf.io/w6spm","title":"Microbiota intestinal e doen\u00e7as neurodegenerativas: uma revis\u00e3o de escopo sobre a rela\u00e7\u00e3o entre disbiose e neurodegenera\u00e7\u00e3o","display_name":"Microbiota intestinal e doen\u00e7as neurodegenerativas: uma revis\u00e3o de escopo sobre a rela\u00e7\u00e3o entre disbiose e neurodegenera\u00e7\u00e3o","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7163402687","doi":"https://doi.org/10.17605/osf.io/w6spm"},"language":"pt","primary_location":{"id":"doi:10.17605/osf.io/w6spm","doi":"https://doi.org/10.17605/osf.io/w6spm","is_oa":true,"landing_page_url":"https://doi.org/10.17605/osf.io/w6spm","pdf_url":null,"source":{"id":"https://openalex.org/S7407050956","display_name":"Open Science Framework","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2799848540","host_organization_name":"Center for Open Science","host_organization_lineage":["https://openalex.org/I2799848540"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"},"parent_works":[],"lineage":["https://openalex.org/W7163402687"],"child_works_count":0,"type":"study-registration","is_traditional":false,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.17605/osf.io/w6spm","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5137470582","display_name":"JULIA EUGENIO MARQUES","orcid":"https://orcid.org/0009-0002-0491-6174","observed_orcids":["https://orcid.org/0009-0002-0491-6174"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MARQUES, JULIA EUGENIO","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-0491-6174","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5018841137","display_name":"Heliara Maria Spina Canela","orcid":"https://orcid.org/0000-0002-4476-3777","observed_orcids":["https://orcid.org/0000-0002-4476-3777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Heliara Maria Spina Canela","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9070000052452087},{"id":"https://openalex.org/keywords/dysbiosis","display_name":"dysbiosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.9990000128746033},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8970000147819519},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/microbiota-modulation","display_name":"microbiota modulation","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5576000213623047},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.32350000739097595},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.2728999853134155},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2563999891281128},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.2556000053882599},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.23100000619888306},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.22939999401569366},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.19470000267028809},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.18950000405311584},{"id":"https://openalex.org/C2780423288","wikidata":"https://www.wikidata.org/wiki/Q7242440","display_name":"Prevotella","level":3,"score":0.16449999809265137}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.17605/osf.io/w6spm","doi":"https://doi.org/10.17605/osf.io/w6spm","is_oa":true,"landing_page_url":"https://doi.org/10.17605/osf.io/w6spm","pdf_url":null,"source":{"id":"https://openalex.org/S7407050956","display_name":"Open Science Framework","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2799848540","host_organization_name":"Center for Open Science","host_organization_lineage":["https://openalex.org/I2799848540"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"}],"best_oa_location":{"id":"doi:10.17605/osf.io/w6spm","doi":"https://doi.org/10.17605/osf.io/w6spm","is_oa":true,"landing_page_url":"https://doi.org/10.17605/osf.io/w6spm","pdf_url":null,"source":{"id":"https://openalex.org/S7407050956","display_name":"Open Science Framework","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2799848540","host_organization_name":"Center for Open Science","host_organization_lineage":["https://openalex.org/I2799848540"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"StudyRegistration"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9907000064849854}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4411334103","https://openalex.org/W4413379665","https://openalex.org/W3083035346","https://openalex.org/W7221555632","https://openalex.org/W4413922257","https://openalex.org/W4372122691","https://openalex.org/W4368341484","https://openalex.org/W7223051990","https://openalex.org/W4368362853","https://openalex.org/W4407087770"],"abstract_inverted_index":{"A":[0],"microbiota":[1,120,146],"intestinal":[2,77],"\u00e9":[3],"formada":[4],"por":[5,21,39],"microrganismos":[6],"essenciais":[7],"para":[8,136],"o":[9,88],"funcionamento":[10],"do":[11,41],"organismo.":[12],"Altera\u00e7\u00f5es":[13],"nessa":[14],"microbiota,":[15],"chamadas":[16],"de":[17,24,32,91,94,99,113],"disbiose,":[18],"podem":[19],"ocorrer":[20],"uma":[22,92],"s\u00e9rie":[23],"fatores":[25,82],"e":[26,37,56,78,84,104,110,123,134,139],"tem":[27,69],"sido":[28],"relacionadas":[29,142],"\u00e0":[30,119,143],"ocorr\u00eancia":[31],"doen\u00e7as":[33,79,124],"neurodegenerativas,":[34,80],"como":[35,70],"Alzheimer":[36],"Parkinson,":[38],"meio":[40],"eixo":[42],"intestino-c\u00e9rebro.":[43],"Entretanto,":[44],"ainda":[45],"n\u00e3o":[46],"se":[47,49,62],"estabeleceu":[48],"a":[50,73,128],"disbiose":[51,76,122],"est\u00e1":[52],"envolvida":[53],"na":[54,97],"fisiopatologia":[55],"desenvolvimento":[57],"das":[58],"condi\u00e7\u00f5es":[59],"neurodegenerativas":[60],"ou":[61],"seriam":[63],"marcadores":[64],"dessa":[65],"condi\u00e7\u00e3o.":[66],"Este":[67],"estudo":[68,100],"objetivo":[71],"analisar":[72],"rela\u00e7\u00e3o":[74],"entre":[75,102],"identificando":[81],"associados":[83],"lacunas":[85],"cient\u00edficas":[86],"sobre":[87,130],"tema.":[89],"Trata-se":[90],"revis\u00e3o":[93],"escopo,":[95],"baseada":[96],"busca":[98],"publicados":[101],"2020":[103],"2026":[105],"nas":[106],"bases":[107],"PubMed,":[108],"SciELO":[109],"no":[111],"banco":[112],"pr\u00e9-prints":[114],"MedRxiv,":[115],"utilizando":[116],"descritores":[117],"relacionados":[118],"intestinal,":[121],"neurodegenerativas.":[125],"Espera-se":[126],"ampliar":[127],"compreens\u00e3o":[129],"os":[131],"mecanismos":[132],"envolvidos":[133],"contribuir":[135],"futuras":[137],"pesquisas":[138],"estrat\u00e9gias":[140],"terap\u00eauticas":[141],"modula\u00e7\u00e3o":[144],"da":[145],"intestinal.":[147]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2026-06-04T00:00:00"}