{"id":"https://openalex.org/W7162965584","doi":null,"title":"Faktor Risiko Terjadinya Sindrom Lisis Tumor Pada Leukemia Limfoblastik Akut Anak","display_name":"Faktor Risiko Terjadinya Sindrom Lisis Tumor Pada Leukemia Limfoblastik Akut Anak","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W7162965584"},"language":"id","primary_location":{"id":"pmh:oai:repository.unair.ac.id:141614","doi":null,"is_oa":true,"landing_page_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","pdf_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","source":{"id":"https://openalex.org/S4306400777","display_name":"Universitas Airlangga Repository (Universitas Airlangga)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205133468","host_organization_name":"Universitas Airlangga","host_organization_lineage":["https://openalex.org/I205133468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079946750","display_name":"Audylia Hartono","orcid":"https://orcid.org/0009-0008-6978-1286","observed_orcids":["https://orcid.org/0009-0008-6978-1286"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"AUDYLIA HARTONO / 011828116303, -","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079946750"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12845","display_name":"Methemoglobinemia and Tumor Lysis Syndrome","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tumor-lysis-syndrome","display_name":"tumor lysis syndrome","score":0.9629999995231628},{"id":"https://openalex.org/keywords/acute-lymphoblastic-leukemia","display_name":"acute lymphoblastic leukemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/pediatric-leukemia","display_name":"pediatric leukemia","score":0.8169999718666077},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9879999756813049},{"id":"https://openalex.org/keywords/hyperuricemia","display_name":"hyperuricemia","score":0.6299999952316284},{"id":"https://openalex.org/keywords/hyperphosphatemia","display_name":"hyperphosphatemia","score":0.7910000085830688},{"id":"https://openalex.org/keywords/hyperkalemia","display_name":"hyperkalemia","score":0.8349999785423279},{"id":"https://openalex.org/keywords/hypercalcemia","display_name":"hypercalcemia","score":0.5609999895095825},{"id":"https://openalex.org/keywords/treatment-failure","display_name":"treatment failure","score":0.47600001096725464},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.5630000233650208},{"id":"https://openalex.org/keywords/acute-respiratory-failure","display_name":"acute respiratory failure","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8823000192642212},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.7876999974250793},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.32899999618530273},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22930000722408295},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.2240000069141388},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.21899999678134918},{"id":"https://openalex.org/C2776863199","wikidata":"https://www.wikidata.org/wiki/Q976388","display_name":"Acute leukemia","level":3,"score":0.21060000360012054},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.2004999965429306},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.19169999659061432},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.18690000474452972}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:repository.unair.ac.id:141614","doi":null,"is_oa":true,"landing_page_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","pdf_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","source":{"id":"https://openalex.org/S4306400777","display_name":"Universitas Airlangga Repository (Universitas Airlangga)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205133468","host_organization_name":"Universitas Airlangga","host_organization_lineage":["https://openalex.org/I205133468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"}],"best_oa_location":{"id":"pmh:oai:repository.unair.ac.id:141614","doi":null,"is_oa":true,"landing_page_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","pdf_url":"https://repository.unair.ac.id/141614/1/011828116303%20BAB%20I.pdf","source":{"id":"https://openalex.org/S4306400777","display_name":"Universitas Airlangga Repository (Universitas Airlangga)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205133468","host_organization_name":"Universitas Airlangga","host_organization_lineage":["https://openalex.org/I205133468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7162965584.pdf","grobid_xml":"https://content.openalex.org/works/W7162965584.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2576796672","https://openalex.org/W3000005753","https://openalex.org/W131960319","https://openalex.org/W3114848751","https://openalex.org/W2571892666","https://openalex.org/W6981714819","https://openalex.org/W3011111904","https://openalex.org/W2785645432","https://openalex.org/W2197475141","https://openalex.org/W2570344245"],"abstract_inverted_index":{"Latar":[0],"Belakang:":[1],"Saat":[2],"ini":[3,113],"dengan":[4,9,27,35,124,167,172,199,208],"kemajuan":[5],"ilmu":[6],"kedokteran,":[7],"pasien":[8,26,42,206,219,225,232],"LLA":[10,28,43],"memiliki":[11],"prognosis":[12],"yang":[13,19,50,91,133,158,212,220,289],"baik,":[14],"dan":[15,24,52,66,139,165,170,230],"angka":[16,22],"kegagalan":[17],"terapi":[18,40],"rendah.":[20],"Namun,":[21],"kematian":[23],"morbiditas":[25],"di":[29,36],"Indonesia":[30],"masih":[31,77],"lebih":[32,80],"tinggi":[33],"dibandingkan":[34],"negara":[37],"maju.":[38],"Kegagalan":[39],"pada":[41,153,252,280,309,319],"salah":[44,55],"satunya":[45,56],"disebabkan":[46],"oleh":[47],"timbulnya":[48],"komplikasi":[49],"berat":[51],"mengancam":[53],"nyawa,":[54],"sindrom":[57,68,88,108,135,142,227,235,277,306,332,337],"lisis":[58,69,89,109,136,143,228,236,278,307,333,338],"tumor.":[59,110,237,334],"Keterlambatan":[60],"klinisi":[61],"dalam":[62,106,161],"mengenali":[63],"faktor":[64,85,151,183,274,303,329],"risiko":[65,86,152,275,304,330],"mendiagnosis":[67],"tumor":[70,90,137,144,229,279,308],"dapat":[71,92,221],"berakibat":[72],"fatal.":[73],"Oleh":[74],"karena":[75],"itu,":[76],"diperlukan":[78],"penelitian":[79],"lanjut":[81],"untuk":[82,102],"mengetahui":[83],"berbagai":[84],"terjadinya":[87,276,305,331],"dicegah":[93],"sedini":[94],"mungkin":[95],"agar":[96],"tidak":[97,140,233,300],"terjadi":[98],"keterlambatan":[99],"tatalaksana":[100,107],"profilaksis":[101],"mencegah":[103],"luaran":[104],"buruk":[105],"Metode:":[111],"Penelitian":[112],"merupakan":[114,182],"studi":[115],"case":[116],"control":[117],"retrospektif":[118,149],"dari":[119,186],"data":[120,163,218],"rekam":[121],"medik":[122],"anak":[123,207],"leukemia":[125,209,281,310,340],"limfoblastik":[126,210,282,311,341],"akut.":[127],"Protokol":[128],"Leukemia":[129],"Limfoblastik":[130],"Akut":[131],"2018":[132],"mengalami":[134,141,226,234],"(kasus)":[138],"(kontrol).":[145],"Penelusuran":[146],"dilakukan":[147],"secara":[148,271,326],"terhadap":[150],"kedua":[154],"kelompok":[155],"tersebut.":[156],"Data":[157],"terkumpul":[159],"disajikan":[160],"bentuk":[162],"deskriptif":[164],"dianalisis":[166],"analisis":[168],"univariat":[169],"multivariat":[171],"regresi":[173],"logistik.":[174],"Nilai":[175],"p<0,05":[176],"dinyatakan":[177],"signifikan":[178,272,301,327],"yaitu":[179],"variabel":[180,187,197,200,241],"bebas":[181,198],"prediktif":[184],"independen":[185],"terikat.":[188,201],"Odd":[189],"Ratio":[190],"(OR)":[191],"menyatakan":[192],"besarnya":[193],"pengaruh":[194],"(kekuatan":[195],"hubungan)":[196],"Hasil:":[202],"Terdapat":[203],"total":[204],"97":[205],"akut":[211,283,312],"memenuhi":[213],"kriteria":[214],"inklusi,":[215],"sebanyak":[216],"81":[217],"dianalisis,":[222],"diantaranya":[223],"27":[224],"54":[231],"Pada":[238],"uji":[239],"statistika,":[240],"infiltrasi":[242,315],"organ":[243],"(p":[244,255,265],"0.007,":[245],"OR":[246,257,267],"6.15":[247],"(95%CI":[248,259,269],"1.64-22.96)),":[249],"jumlah":[250,317],"leukosit":[251,318],"awal":[253,320],"terdiagnosis":[254],"0.043,":[256],"11.84":[258],"1.08-129.59)),":[260],"serta":[261,295,322],"penurunan":[262,323],"fungsi":[263,324],"ginjal":[264],"0.005,":[266],"28.48":[268],"2.74-295.57))":[270],"menjadi":[273,328],"anak.":[284,313],"Sedangkan":[285],"jenis":[286],"protokol":[287],"kemoterapi":[288,343],"dijalani":[290],"pasien,":[291],"adanya":[292],"massa":[293],"mediastinum,":[294],"peningkatan":[296],"kadar":[297],"asam":[298],"urat":[299],"sebagai":[302],"Kesimpulan:":[314],"organ,":[316],"terdiagnosis,":[321],"ginjal,":[325],"Kata":[335],"Kunci:":[336],"tumor,":[339],"akut,":[342],"induksi":[344]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-06-01T00:00:00"}