{"id":"https://openalex.org/W7162302012","doi":"https://doi.org/10.1016/j.xjse.2026.100131","title":"Outcomes, survival, mortality, and major adverse events in aortic valve replacement surgeries in Africa: A systematic review and meta-analysis","display_name":"Outcomes, survival, mortality, and major adverse events in aortic valve replacement surgeries in Africa: A systematic review and meta-analysis","publication_year":2026,"publication_date":"2026-05-25","ids":{"openalex":"https://openalex.org/W7162302012","doi":"https://doi.org/10.1016/j.xjse.2026.100131","pmid":"https://pubmed.ncbi.nlm.nih.gov/42857357","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13650436"},"language":"en","primary_location":{"id":"doi:10.1016/j.xjse.2026.100131","doi":"https://doi.org/10.1016/j.xjse.2026.100131","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xjse.2026.100131","pdf_url":null,"source":{"id":"https://openalex.org/S4404676284","display_name":"JTCVS structural and endovascular.","issn_l":"2950-6050","issn":["2950-6050"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JTCVS Structural and Endovascular","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.xjse.2026.100131","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5095384000","display_name":"Victory Bassey Effiom","orcid":"https://orcid.org/0000-0001-7963-7079","observed_orcids":["https://orcid.org/0000-0001-7963-7079"]},"institutions":[{"id":"https://openalex.org/I3970730","display_name":"University of Calabar","ror":"https://ror.org/05qderh61","country_code":"NG","type":"education","lineage":["https://openalex.org/I3970730"]}],"countries":["NG"],"is_corresponding":true,"raw_author_name":"Victory Bassey Effiom","raw_affiliation_strings":["Faculty of Clinical Sciences, University of Calabar, Calabar, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Clinical Sciences, University of Calabar, Calabar, Nigeria","institution_ids":["https://openalex.org/I3970730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092208383","display_name":"Victor Oluwafemi Femi\u2010Lawal","orcid":"https://orcid.org/0000-0003-2747-1681","observed_orcids":["https://orcid.org/0000-0003-2747-1681"]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Victor Oluwafemi Femi-Lawal","raw_affiliation_strings":["College of Medicine, University of Ibadan, Ibadan, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, University of Ibadan, Ibadan, Nigeria","institution_ids":["https://openalex.org/I181631907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009960932","display_name":"Atharv Oak","orcid":"https://orcid.org/0000-0003-1441-520X","observed_orcids":["https://orcid.org/0000-0003-1441-520X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Atharv Vivek Oak","raw_affiliation_strings":["Johns Hopkins School of Medicine, Baltimore, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins School of Medicine, Baltimore, Md","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134490823","display_name":"Oluwasegun Oyesola","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Oluwasegun John Oyesola","raw_affiliation_strings":["College of Medicine, University of Ibadan, Ibadan, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, University of Ibadan, Ibadan, Nigeria","institution_ids":["https://openalex.org/I181631907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108712014","display_name":"Fatma K. Ahmed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12859529","display_name":"University of Nairobi","ror":"https://ror.org/02y9nww90","country_code":"KE","type":"education","lineage":["https://openalex.org/I12859529"]}],"countries":["KE"],"is_corresponding":false,"raw_author_name":"Fatma Kamal Ahmed","raw_affiliation_strings":["Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Nairobi, Nairobi, Kenya","institution_ids":["https://openalex.org/I12859529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093958882","display_name":"Samuel G. J. Fodop","orcid":"https://orcid.org/0000-0001-5146-8795","observed_orcids":["https://orcid.org/0000-0001-5146-8795"]},"institutions":[{"id":"https://openalex.org/I251854046","display_name":"Catholic University of Cameroon","ror":"https://ror.org/00xq3k060","country_code":"CM","type":"education","lineage":["https://openalex.org/I251854046"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Samuel Ghislain Junior Fodop","raw_affiliation_strings":["School of Health and Medical Sciences, Catholic University of Cameroon, Bamenda, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Health and Medical Sciences, Catholic University of Cameroon, Bamenda, Cameroon","institution_ids":["https://openalex.org/I251854046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061115178","display_name":"Michael Anayo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Michael James Anayo","raw_affiliation_strings":["College of Medicine, University of Ibadan, Ibadan, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, University of Ibadan, Ibadan, Nigeria","institution_ids":["https://openalex.org/I181631907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115878248","display_name":"Achanga Bill-Smith Anyinkeng","orcid":"https://orcid.org/0000-0003-1963-6909","observed_orcids":["https://orcid.org/0000-0003-1963-6909"]},"institutions":[{"id":"https://openalex.org/I251854046","display_name":"Catholic University of Cameroon","ror":"https://ror.org/00xq3k060","country_code":"CM","type":"education","lineage":["https://openalex.org/I251854046"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Achanga Bill-Smith Anyinkeng","raw_affiliation_strings":["School of Health and Medical Sciences, Catholic University of Cameroon, Bamenda, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Health and Medical Sciences, Catholic University of Cameroon, Bamenda, Cameroon","institution_ids":["https://openalex.org/I251854046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121186322","display_name":"Jonas Paul Ibekwe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Jonas Paul Ibekwe","raw_affiliation_strings":["College of Medicine, University of Ibadan, Ibadan, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, University of Ibadan, Ibadan, Nigeria","institution_ids":["https://openalex.org/I181631907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119737026","display_name":"Kolawole Olalekan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181631907","display_name":"University of Ibadan","ror":"https://ror.org/03wx2rr30","country_code":"NG","type":"education","lineage":["https://openalex.org/I181631907"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Kolawole Victor Olalekan","raw_affiliation_strings":["College of Medicine, University of Ibadan, Ibadan, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Medicine, University of Ibadan, Ibadan, Nigeria","institution_ids":["https://openalex.org/I181631907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012599916","display_name":"Samuel Girma","orcid":"https://orcid.org/0000-0002-0630-4553","observed_orcids":["https://orcid.org/0000-0002-0630-4553"]},"institutions":[{"id":"https://openalex.org/I4537092","display_name":"Addis Ababa University","ror":"https://ror.org/038b8e254","country_code":"ET","type":"education","lineage":["https://openalex.org/I4537092"]}],"countries":["ET"],"is_corresponding":false,"raw_author_name":"Samuel Mesfin Girma","raw_affiliation_strings":["School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia","institution_ids":["https://openalex.org/I4537092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106801956","display_name":"Daniel Brabi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I254651091","display_name":"University of Health and Allied Sciences","ror":"https://ror.org/054tfvs49","country_code":"GH","type":"education","lineage":["https://openalex.org/I254651091"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Daniel Brabi","raw_affiliation_strings":["School of Medicine, University of Health and Allied Sciences, Ho, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, University of Health and Allied Sciences, Ho, Ghana","institution_ids":["https://openalex.org/I254651091"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078067868","display_name":"Ahmet K\u0131l\u0131\u00e7","orcid":"https://orcid.org/0000-0002-2365-3093","observed_orcids":["https://orcid.org/0000-0002-2365-3093"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ahmet Kilic","raw_affiliation_strings":["Division of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiac Surgery, Department of Surgery, Johns Hopkins Hospital, Baltimore, Md","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5095384000"],"corresponding_institution_ids":["https://openalex.org/I3970730"],"apc_list":{"value":2500,"currency":"USD","value_usd":2500},"apc_paid":{"value":2500,"currency":"USD","value_usd":2500},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.2364928,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":null,"first_page":"100131","last_page":"100131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aortic-valve-replacement","display_name":"aortic valve replacement","score":0.9990000128746033},{"id":"https://openalex.org/keywords/surgical-outcomes","display_name":"surgical outcomes","score":0.9179999828338623},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.7839999794960022},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.9940000176429749},{"id":"https://openalex.org/keywords/major-adverse-events","display_name":"major adverse events","score":0.996999979019165},{"id":"https://openalex.org/keywords/africa","display_name":"Africa","score":0.7009999752044678},{"id":"https://openalex.org/keywords/sub-saharan-africa","display_name":"sub-Saharan Africa","score":0.5080000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.857200026512146},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6394000053405762},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.59170001745224},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.453000009059906},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.44429999589920044},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.43950000405311584},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43299999833106995},{"id":"https://openalex.org/C2780026749","wikidata":"https://www.wikidata.org/wiki/Q7912830","display_name":"Valve replacement","level":3,"score":0.4194999933242798},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.30469998717308044},{"id":"https://openalex.org/C2778715743","wikidata":"https://www.wikidata.org/wiki/Q181802","display_name":"Prosthesis","level":2,"score":0.2994999885559082},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C2779662365","wikidata":"https://www.wikidata.org/wiki/Q5416694","display_name":"Event (particle physics)","level":2,"score":0.2624000012874603},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.2605000138282776},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.25130000710487366}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1016/j.xjse.2026.100131","doi":"https://doi.org/10.1016/j.xjse.2026.100131","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xjse.2026.100131","pdf_url":null,"source":{"id":"https://openalex.org/S4404676284","display_name":"JTCVS structural and endovascular.","issn_l":"2950-6050","issn":["2950-6050"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JTCVS Structural and Endovascular","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13650436","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13650436/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13650436/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JTCVS Struct Endovasc","raw_type":"Text"},{"id":"pmid:42857357","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42857357","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JTCVS structural and endovascular","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:84440551b2d04a0da626322ce8849fb3","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/84440551b2d04a0da626322ce8849fb3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JTCVS Structural and Endovascular, Vol 11, Iss , Pp 100131- (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.xjse.2026.100131","doi":"https://doi.org/10.1016/j.xjse.2026.100131","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xjse.2026.100131","pdf_url":null,"source":{"id":"https://openalex.org/S4404676284","display_name":"JTCVS structural and endovascular.","issn_l":"2950-6050","issn":["2950-6050"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JTCVS Structural and Endovascular","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1882986778","https://openalex.org/W1982324383","https://openalex.org/W2000363524","https://openalex.org/W2061768484","https://openalex.org/W2144119781","https://openalex.org/W2149609916","https://openalex.org/W2177563904","https://openalex.org/W2272852096","https://openalex.org/W2473336843","https://openalex.org/W2586118148","https://openalex.org/W2735485141","https://openalex.org/W2743573657","https://openalex.org/W2745876251","https://openalex.org/W2765788408","https://openalex.org/W2796036502","https://openalex.org/W2807867256","https://openalex.org/W2884557850","https://openalex.org/W2930844345","https://openalex.org/W2955650504","https://openalex.org/W3015894395","https://openalex.org/W3016242052","https://openalex.org/W3093606518","https://openalex.org/W3118615836","https://openalex.org/W3173196666","https://openalex.org/W3182905236","https://openalex.org/W3185071566","https://openalex.org/W4206346449","https://openalex.org/W4225163320","https://openalex.org/W4239414585","https://openalex.org/W4285410769","https://openalex.org/W4293206916","https://openalex.org/W4312018392","https://openalex.org/W4382176418","https://openalex.org/W4387711213","https://openalex.org/W4391744346","https://openalex.org/W4406072022","https://openalex.org/W4407846336"],"related_works":["https://openalex.org/W7155551924","https://openalex.org/W4408287330","https://openalex.org/W4389850959","https://openalex.org/W2884557850","https://openalex.org/W6946261169","https://openalex.org/W7015039256","https://openalex.org/W2473204270","https://openalex.org/W4387950137","https://openalex.org/W2115282741","https://openalex.org/W2115712323"],"abstract_inverted_index":{"Objectives:":[0],"Aortic":[1,153],"valve":[2,12,84,94,171],"replacement":[3,85],"(AVR)":[4],"is":[5],"the":[6,101,109,245],"definitive":[7],"treatment":[8],"for":[9,43,57],"severe":[10],"aortic":[11,83,93,170],"disease,":[13],"yet":[14],"outcome":[15],"data":[16],"from":[17,143],"Africa":[18,224],"remain":[19],"scarce.":[20],"This":[21],"systematic":[22],"review":[23],"and":[24,29,46,53,72,91,108,118,156,168,195,212,217,228,252],"meta-analysis":[25],"assessed":[26,99],"survival,":[27,114],"mortality,":[28,115],"major":[30],"adverse":[31],"events":[32],"after":[33],"AVR":[34,60,80,221],"across":[35,133],"Africa.":[36],"Methods:":[37],"Adhering":[38],"to":[39],"Preferred":[40],"Reporting":[41],"Items":[42],"Systematic":[44],"reviews":[45],"Meta-Analyses":[47],"guidelines,":[48],"we":[49],"searched":[50],"PubMed,":[51],"Embase,":[52],"Web":[54],"of":[55,104,215],"Science":[56],"studies":[58,126,129,141],"reporting":[59],"outcomes":[61,222],"in":[62,223],"African":[63,135],"populations,":[64],"covering":[65],"randomized":[66],"trials,":[67],"cohort":[68],"studies,":[69],"case":[70,73],"series,":[71],"reports.":[74],"Subgroup":[75],"analyses":[76],"were":[77,137,142,151],"conducted":[78],"by":[79],"modality:":[81],"surgical":[82],"(SAVR),":[86],"minimally":[87,164],"invasive":[88,165],"surgery":[89,166],"(MICS),":[90],"transcatheter":[92,169],"implantation.":[95],"Study":[96],"quality":[97],"was":[98,147,177,201,205],"using":[100],"Cochrane":[102],"Risk":[103],"Bias":[105],"tool":[106],"2":[107],"Newcastle-Ottawa":[110],"Scale.":[111],"Outcomes":[112],"included":[113,161,181],"echocardiographic":[116],"improvements,":[117],"valve-":[119],"or":[120],"procedure-related":[121],"complications.":[122],"Results:":[123],"Of":[124],"2547":[125],"screened,":[127],"21":[128],"involving":[130],"1303":[131],"patients":[132],"6":[134],"countries":[136],"included;":[138],"15":[139],"(71.4%)":[140],"Egypt.":[144],"Mean":[145],"age":[146],"60.4":[148],"years;":[149],"43.3%":[150],"female.":[152],"stenosis":[154],"(70.4%)":[155],"regurgitation":[157],"(64.0%)":[158],"predominated.":[159],"Modalities":[160],"SAVR":[162],"(45.1%),":[163],"(27.8%),":[167],"implantation":[172],"(27.1%).":[173],"Technical":[174],"success":[175,227],"rate":[176,200,230],"high":[178],"(97.5%-100%).":[179],"Complications":[180,249],"arrhythmias":[182,251],"(16.0%),":[183],"postoperative":[184,253],"bleeding":[185,254],"(15.0%),":[186],"paravalvular":[187],"leak":[188],"(5.0%),":[189,194],"pacemaker":[190],"requirement":[191],"(6.0%),":[192],"stroke":[193],"myocardial":[196],"infarction":[197],"(3.0%).":[198],"Reoperation":[199],"4.4%.":[202],"Thirty-day":[203],"mortality":[204],"5.0%":[206],"(95%":[207],"CI.":[208],"3.1%-8.1%),":[209],"with":[210],"1-year":[211],"5-year":[213],"survival":[214,229],"93.2%":[216],"91.0%,":[218],"respectively.":[219],"Conclusions:":[220],"show":[225],"favorable":[226],"although":[231],"below":[232],"optimal":[233],"benchmarks":[234],"despite":[235],"resource":[236],"constraints.":[237],"However,":[238],"results":[239],"are":[240],"not":[241],"generalizable":[242],"continent-wide,":[243],"given":[244],"heavy":[246],"geographic":[247],"skew.":[248],"including":[250],"necessitate":[255],"enhanced":[256],"perioperative":[257],"protocols.":[258]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2026-05-26T00:00:00"}