{"id":"https://openalex.org/W7161061925","doi":"https://doi.org/10.1163/18762891-bja00118","title":"Gut commensal Bacteroides faecichinchillae, a potential novel candidate of next-generation probiotics targeting type 2 diabetes","display_name":"Gut commensal Bacteroides faecichinchillae, a potential novel candidate of next-generation probiotics targeting type 2 diabetes","publication_year":2026,"publication_date":"2026-05-12","ids":{"openalex":"https://openalex.org/W7161061925","doi":"https://doi.org/10.1163/18762891-bja00118","pmid":"https://pubmed.ncbi.nlm.nih.gov/42128408"},"language":"en","primary_location":{"id":"doi:10.1163/18762891-bja00118","doi":"https://doi.org/10.1163/18762891-bja00118","is_oa":false,"landing_page_url":"https://doi.org/10.1163/18762891-bja00118","pdf_url":null,"source":{"id":"https://openalex.org/S150142394","display_name":"Beneficial Microbes","issn_l":"1876-2883","issn":["1876-2883","1876-2891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial Microbes","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058075432","display_name":"M. Godet","orcid":"https://orcid.org/0000-0001-9879-4731","observed_orcids":["https://orcid.org/0000-0001-9879-4731"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M. Godet","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":"https://orcid.org/0000-0001-9879-4731","affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057097815","display_name":"Eve Delmas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I198244214","display_name":"Universit\u00e9 Clermont Auvergne","ror":"https://ror.org/01a8ajp46","country_code":"FR","type":"education","lineage":["https://openalex.org/I198244214"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210133202","display_name":"Microbiologie Environnement Digestif Sant\u00e9","ror":"https://ror.org/03d0rdy88","country_code":"FR","type":"facility","lineage":["https://openalex.org/I198244214","https://openalex.org/I4210088668","https://openalex.org/I4210133202"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E. Delmas","raw_affiliation_strings":["UMR MEDIS, INRAE U454, Universite\u0301 Clermont-Auvergne, Saint-Gene\u0300s-Champanelle, 63122, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UMR MEDIS, INRAE U454, Universite\u0301 Clermont-Auvergne, Saint-Gene\u0300s-Champanelle, 63122, France","institution_ids":["https://openalex.org/I198244214","https://openalex.org/I4210088668","https://openalex.org/I4210133202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103797827","display_name":"Christelle G\u00e9rard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Ge\u0301rard","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013042347","display_name":"Emmanuelle Meugnier","orcid":"https://orcid.org/0000-0002-2291-7691","observed_orcids":["https://orcid.org/0000-0002-2291-7691"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"E. Meugnier","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":"https://orcid.org/0000-0002-2291-7691","affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047808519","display_name":"A. Bravard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A. Bravard","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020274699","display_name":"Claudie Pinteur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C. Pinteur","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111879900","display_name":"Nathalie V\u00e9ga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"N. Vega","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060336585","display_name":"N Bendridi","orcid":"https://orcid.org/0000-0003-0456-7007","observed_orcids":["https://orcid.org/0000-0003-0456-7007"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"N. Bendridi","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":"https://orcid.org/0000-0003-0456-7007","affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022204488","display_name":"David Cheillan","orcid":"https://orcid.org/0000-0001-9535-2567","observed_orcids":["https://orcid.org/0000-0001-9535-2567"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D. Cheillan","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","Service de Biochimie et Biologie Mole\u0301culaire, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, 69500 Bron, France"],"raw_orcid":"https://orcid.org/0000-0001-9535-2567","affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]},{"raw_affiliation_string":"Service de Biochimie et Biologie Mole\u0301culaire, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, 69500 Bron, France","institution_ids":["https://openalex.org/I4210100596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042635985","display_name":"Salma Fourati","orcid":"https://orcid.org/0000-0002-8025-8575","observed_orcids":["https://orcid.org/0000-0002-8025-8575"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S. Fourati","raw_affiliation_strings":["Sorbonne Universite\u0301, Centre de Recherche Saint-Antoine, INSERM U938, 75012 Paris, France"],"raw_orcid":"https://orcid.org/0000-0002-8025-8575","affiliations":[{"raw_affiliation_string":"Sorbonne Universite\u0301, Centre de Recherche Saint-Antoine, INSERM U938, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210134622"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076013292","display_name":"Dominique P. Rainteau","orcid":"https://orcid.org/0000-0001-8571-5045","observed_orcids":["https://orcid.org/0000-0001-8571-5045"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210134622","display_name":"Centre de Recherche Saint-Antoine","ror":"https://ror.org/03wxndv36","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210097159","https://openalex.org/I4210129850","https://openalex.org/I4210134622"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D. Rainteau","raw_affiliation_strings":["Sorbonne Universite\u0301, Centre de Recherche Saint-Antoine, INSERM U938, 75012 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sorbonne Universite\u0301, Centre de Recherche Saint-Antoine, INSERM U938, 75012 Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210134622"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008268817","display_name":"M. Le Barz","orcid":"https://orcid.org/0000-0002-2112-5254","observed_orcids":["https://orcid.org/0000-0002-2112-5254"]},"institutions":[{"id":"https://openalex.org/I4210098871","display_name":"Lallemand (France)","ror":"https://ror.org/014cdjz51","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210098871","https://openalex.org/I4210145371"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M. Le Barz","raw_affiliation_strings":["Lallemand Health Solutions, 31702 Blagnac, France"],"raw_orcid":"https://orcid.org/0000-0002-2112-5254","affiliations":[{"raw_affiliation_string":"Lallemand Health Solutions, 31702 Blagnac, France","institution_ids":["https://openalex.org/I4210098871"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038396674","display_name":"Sylvie Binda","orcid":"https://orcid.org/0009-0002-3939-4118","observed_orcids":["https://orcid.org/0009-0002-3939-4118"]},"institutions":[{"id":"https://openalex.org/I4210098871","display_name":"Lallemand (France)","ror":"https://ror.org/014cdjz51","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210098871","https://openalex.org/I4210145371"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S. Binda","raw_affiliation_strings":["Lallemand Health Solutions, 31702 Blagnac, France"],"raw_orcid":"https://orcid.org/0009-0002-3939-4118","affiliations":[{"raw_affiliation_string":"Lallemand Health Solutions, 31702 Blagnac, France","institution_ids":["https://openalex.org/I4210098871"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020742210","display_name":"Fran\u00e7ois Leulier","orcid":"https://orcid.org/0000-0002-4542-3053","observed_orcids":["https://orcid.org/0000-0002-4542-3053"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I113428412","display_name":"\u00c9cole Normale Sup\u00e9rieure de Lyon","ror":"https://ror.org/04zmssz18","country_code":"FR","type":"education","lineage":["https://openalex.org/I113428412","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210125167","display_name":"Institut de G\u00e9nomique Fonctionnelle de Lyon","ror":"https://ror.org/038fcbc74","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210125167"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F. Leulier","raw_affiliation_strings":["Institut de Ge\u0301nomique Fonctionnelle de Lyon, Ecole Normale Supe\u0301rieure de Lyon, CNRS UMR5242, UCBL Lyon-1, 69007 Lyon, France"],"raw_orcid":"https://orcid.org/0000-0002-4542-3053","affiliations":[{"raw_affiliation_string":"Institut de Ge\u0301nomique Fonctionnelle de Lyon, Ecole Normale Supe\u0301rieure de Lyon, CNRS UMR5242, UCBL Lyon-1, 69007 Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I4210125167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056227939","display_name":"Annick Bernalier\u2010Donadille","orcid":"https://orcid.org/0000-0001-7541-4417","observed_orcids":["https://orcid.org/0000-0001-7541-4417"]},"institutions":[{"id":"https://openalex.org/I198244214","display_name":"Universit\u00e9 Clermont Auvergne","ror":"https://ror.org/01a8ajp46","country_code":"FR","type":"education","lineage":["https://openalex.org/I198244214"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210133202","display_name":"Microbiologie Environnement Digestif Sant\u00e9","ror":"https://ror.org/03d0rdy88","country_code":"FR","type":"facility","lineage":["https://openalex.org/I198244214","https://openalex.org/I4210088668","https://openalex.org/I4210133202"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"A. Bernalier-Donadille","raw_affiliation_strings":["UMR MEDIS, INRAE U454, Universite\u0301 Clermont-Auvergne, Saint-Gene\u0300s-Champanelle, 63122, France"],"raw_orcid":"https://orcid.org/0000-0001-7541-4417","affiliations":[{"raw_affiliation_string":"UMR MEDIS, INRAE U454, Universite\u0301 Clermont-Auvergne, Saint-Gene\u0300s-Champanelle, 63122, France","institution_ids":["https://openalex.org/I198244214","https://openalex.org/I4210088668","https://openalex.org/I4210133202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048369934","display_name":"Hubert Vidal","orcid":"https://orcid.org/0000-0002-9467-0317","observed_orcids":["https://orcid.org/0000-0002-9467-0317"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210126950","display_name":"Laboratoire de recherche en cardiovasculaire, m\u00e9tabolisme, diab\u00e9tologie et nutrition","ror":"https://ror.org/03bbjky47","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210100596","https://openalex.org/I4210126950"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"H. Vidal","raw_affiliation_strings":["Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France"],"raw_orcid":"https://orcid.org/0000-0002-9467-0317","affiliations":[{"raw_affiliation_string":"Laboratoire CarMeN, INSERM U1060, INRAE U1397, https://dx.doi.org/27098Universite\u0301 Lyon 1, 69495 Pierre-Be\u0301nite, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210088668","https://openalex.org/I4210126950"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":13,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"17"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.5313000082969666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.5313000082969666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.4595000147819519,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.8159999847412109},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":1.0},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.8339999914169312},{"id":"https://openalex.org/keywords/high-fat-high-sugar-diet","display_name":"high-fat high-sugar diet","score":0.8840000033378601},{"id":"https://openalex.org/keywords/glucose-tolerance","display_name":"glucose tolerance","score":0.9100000262260437},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.7799999713897705},{"id":"https://openalex.org/keywords/bile-acids","display_name":"bile acids","score":0.9110000133514404},{"id":"https://openalex.org/keywords/metformin-combination-therapy","display_name":"metformin combination therapy","score":0.7250000238418579},{"id":"https://openalex.org/keywords/akkermansia-muciniphila","display_name":"Akkermansia muciniphila","score":0.8730000257492065},{"id":"https://openalex.org/keywords/dysbiosis","display_name":"dysbiosis","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.8055999875068665},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.7226999998092651},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.6643999814987183},{"id":"https://openalex.org/C2778168646","wikidata":"https://www.wikidata.org/wiki/Q133186","display_name":"Bacteroides","level":3,"score":0.6344000101089478},{"id":"https://openalex.org/C2780988686","wikidata":"https://www.wikidata.org/wiki/Q14375936","display_name":"Hyperinsulinemia","level":4,"score":0.5328999757766724},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.4309000074863434},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.413100004196167},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3928000032901764},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.3912999927997589},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.38040000200271606},{"id":"https://openalex.org/C2780246119","wikidata":"https://www.wikidata.org/wiki/Q221817","display_name":"Bacteroides fragilis","level":3,"score":0.37790000438690186},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.3720000088214874},{"id":"https://openalex.org/C2779399885","wikidata":"https://www.wikidata.org/wiki/Q413288","display_name":"Bile acid","level":2,"score":0.3682999908924103},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.3644999861717224},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3598000109195709},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3553999960422516},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.3431999981403351},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3305000066757202},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3212999999523163},{"id":"https://openalex.org/C2776357993","wikidata":"https://www.wikidata.org/wiki/Q4840030","display_name":"Bacteroidaceae","level":3,"score":0.31119999289512634},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.3073999881744385},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3059000074863434},{"id":"https://openalex.org/C192989942","wikidata":"https://www.wikidata.org/wiki/Q68685","display_name":"Metabolic pathway","level":3,"score":0.30000001192092896},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.27720001339912415},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.26910001039505005},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.26840001344680786},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.265500009059906},{"id":"https://openalex.org/C2992479659","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut bacteria","level":3,"score":0.26100000739097595},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.25450000166893005}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1163/18762891-bja00118","doi":"https://doi.org/10.1163/18762891-bja00118","is_oa":false,"landing_page_url":"https://doi.org/10.1163/18762891-bja00118","pdf_url":null,"source":{"id":"https://openalex.org/S150142394","display_name":"Beneficial Microbes","issn_l":"1876-2883","issn":["1876-2883","1876-2891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial Microbes","raw_type":"journal-article"},{"id":"pmid:42128408","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42128408","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Beneficial microbes","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05625604v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.inrae.fr/hal-05625604","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Beneficial Microbes, In press, pp.1-17. &#x27E8;10.1163/18762891-bja00118&#x27E9;","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1479800487","https://openalex.org/W2005292739","https://openalex.org/W2006404454","https://openalex.org/W2023615726","https://openalex.org/W2034025647","https://openalex.org/W2038217946","https://openalex.org/W2041335894","https://openalex.org/W2057508104","https://openalex.org/W2071841602","https://openalex.org/W2073332363","https://openalex.org/W2093443755","https://openalex.org/W2116425227","https://openalex.org/W2121797177","https://openalex.org/W2139334262","https://openalex.org/W2143613048","https://openalex.org/W2151476184","https://openalex.org/W2167062509","https://openalex.org/W2236340720","https://openalex.org/W2528626298","https://openalex.org/W2551836896","https://openalex.org/W2559267012","https://openalex.org/W2617940752","https://openalex.org/W2651468154","https://openalex.org/W2883853179","https://openalex.org/W2885853345","https://openalex.org/W2889208646","https://openalex.org/W2898587007","https://openalex.org/W2912815879","https://openalex.org/W2944330168","https://openalex.org/W2954124338","https://openalex.org/W2966271547","https://openalex.org/W2969920107","https://openalex.org/W3024651515","https://openalex.org/W3108344129","https://openalex.org/W3154019251","https://openalex.org/W3193729266","https://openalex.org/W4280613468","https://openalex.org/W4281555356","https://openalex.org/W4283807244","https://openalex.org/W4296106410","https://openalex.org/W4386493173","https://openalex.org/W4388850106","https://openalex.org/W4393002876","https://openalex.org/W4394770376","https://openalex.org/W4394809656","https://openalex.org/W4400732359","https://openalex.org/W4401514467","https://openalex.org/W4404539390","https://openalex.org/W4405332697","https://openalex.org/W4405810616","https://openalex.org/W4414709132"],"related_works":["https://openalex.org/W4405285108","https://openalex.org/W3148217602","https://openalex.org/W2969092691","https://openalex.org/W2088994087","https://openalex.org/W4389380930","https://openalex.org/W4362633046","https://openalex.org/W4283025769","https://openalex.org/W4387429056","https://openalex.org/W4385620427","https://openalex.org/W4292483819"],"abstract_inverted_index":{"The":[0,170],"implication":[1],"of":[2,8,13,23,32,83,87,109,149,155,163,167,187,209,216],"gut":[3,210],"microbiota":[4,211],"in":[5,62,94,129,179,191,199,270],"the":[6,14,21,30,77,81,84,88,180,188,192,214,273],"pathophysiology":[7],"type":[9,63,266],"2":[10,64,267],"diabetes,":[11,268],"one":[12],"major":[15],"health":[16],"concerns":[17],"worldwide,":[18],"has":[19],"demonstrated":[20],"benefits":[22],"using":[24],"probiotics":[25,263],"to":[26,36,50,58,176,264],"improve":[27,59],"dysbiosis.":[28],"Facing":[29],"lack":[31],"defined":[33],"research":[34],"strategy":[35],"found":[37],"and":[38,53,76,125,185,239,252],"qualify":[39],"bacterial":[40],"with":[41,113,159,206,213,272],"real":[42],"antidiabetic":[43,85],"activity,":[44],"we":[45,69,145],"have":[46],"developed":[47],"a":[48,97],"program":[49],"identify,":[51],"select":[52],"validate":[54],"novel":[55],"strains":[56,256],"able":[57],"metabolic":[60,223],"alterations":[61],"diabetes.":[65],"Among":[66],"potential":[67,86],"candidates,":[68],"identified":[70],"Bacteroides":[71],"faecichinchillae":[72,255],"(named":[73],"BAfa":[74,92,119,147,194,251],"hereafter),":[75],"present":[78],"work":[79],"presents":[80],"validation":[82],"ST37":[89],"(DSMZ":[90],"26883)":[91],"strain":[93],"mice":[95,202],"fed":[96,131,201],"high-fat":[98],"high-sucrose":[99],"(HFS)":[100],"diet":[101],"for":[102,220,240,260],"10":[103],"weeks":[104,108,154,198],"followed":[105],"by":[106],"4":[107,197],"treatment.":[110,245],"Daily":[111],"gavage":[112],"live,":[114],"but":[115],"not":[116],"heat":[117],"inactivated,":[118],"improved":[120],"glucose":[121],"tolerance,":[122],"fasting":[123],"hyperinsulinemia":[124],"liver":[126],"triglyceride":[127],"content":[128],"HFS":[130,200],"mice.":[132],"Furthermore,":[133],"these":[134,247],"beneficial":[135,222],"effects":[136],"were":[137],"retained":[138],"after":[139],"lyophilization.":[140],"Using":[141],"this":[142],"preclinical":[143],"model,":[144],"characterised":[146],"mechanism":[148,172],"action,":[150],"showing":[151],"that":[152,250],"four":[153],"treatment":[156],"was":[157,203],"associated":[158,205],"reduced":[160],"hepatic":[161],"accumulation":[162],"ceramides,":[164],"key":[165],"actors":[166],"insulin":[168],"resistance.":[169],"underlying":[171],"could":[173,257],"be":[174,258],"related":[175,253],"BAfa-induced":[177],"changes":[178],"intestinal":[181],"bile":[182],"acid":[183],"profile":[184],"inhibition":[186],"Fxr-Fgf15":[189],"pathway":[190],"ileum.":[193],"supplementation":[195],"during":[196,243],"also":[204],"mild":[207],"modifications":[208],"composition,":[212],"upregulation":[215],"several":[217],"species":[218],"known":[219],"their":[221],"actions":[224],"(such":[225],"as":[226],"Lactobacillus":[227],"johnsonii,":[228],"Limosilactobacillus":[229],"reutei,":[230],"Roseburia,":[231],"Turicimonas":[232],"muris,":[233],"Phocaeicola":[234],"dorei":[235],"or":[236],"Akkermansia":[237],"muciniphila)":[238],"being":[241],"up-regulated":[242],"metformin":[244],"Altogether,":[246],"data":[248],"indicate":[249],"B.":[254],"considered":[259],"developing":[261],"next-generation":[262],"treat":[265],"potentially":[269],"combination":[271],"anti-diabetic":[274],"drug":[275],"metformin.":[276]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-05-14T00:00:00"}
