{"id":"https://openalex.org/W7160378696","doi":"https://doi.org/10.1016/j.idnow.2026.105281","title":"Tick-borne encephalitis emergence as the third leading cause of encephalitis/meningoencephalitis in western Auvergne-Rh\u00f4ne-Alpes, France","display_name":"Tick-borne encephalitis emergence as the third leading cause of encephalitis/meningoencephalitis in western Auvergne-Rh\u00f4ne-Alpes, France","publication_year":2026,"publication_date":"2026-05-01","ids":{"openalex":"https://openalex.org/W7160378696","doi":"https://doi.org/10.1016/j.idnow.2026.105281","pmid":"https://pubmed.ncbi.nlm.nih.gov/42086146"},"language":"en","primary_location":{"id":"doi:10.1016/j.idnow.2026.105281","doi":"https://doi.org/10.1016/j.idnow.2026.105281","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.idnow.2026.105281","pdf_url":null,"source":{"id":"https://openalex.org/S4210196242","display_name":"Infectious Diseases Now","issn_l":"2666-9919","issn":["2666-9919","2666-9927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infectious Diseases Now","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.idnow.2026.105281","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"\u00c9milie Mayer","orcid":"https://orcid.org/0009-0000-4815-6176","observed_orcids":["https://orcid.org/0009-0000-4815-6176"]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"\u00c9milie Mayer","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France. Electronic address: emilie.mayer@chu-st-etienne.fr"],"raw_orcid":"https://orcid.org/0009-0000-4815-6176","affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France. Electronic address: emilie.mayer@chu-st-etienne.fr","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027080443","display_name":"Aur\u00e9lie Velay","orcid":"https://orcid.org/0000-0002-9174-8959","observed_orcids":["https://orcid.org/0000-0002-9174-8959"]},"institutions":[{"id":"https://openalex.org/I4210145324","display_name":"H\u00f4pitaux Universitaires de Strasbourg","ror":"https://ror.org/04bckew43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210145324"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aur\u00e9lie Velay","raw_affiliation_strings":["Virology Laboratory, Strasbourg University Hospital, 1 place de l'h\u00f4pital, 426 67091 Strasbourg cedex, France"],"raw_orcid":"https://orcid.org/0000-0002-9174-8959","affiliations":[{"raw_affiliation_string":"Virology Laboratory, Strasbourg University Hospital, 1 place de l'h\u00f4pital, 426 67091 Strasbourg cedex, France","institution_ids":["https://openalex.org/I4210145324"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109258475","display_name":"C\u00e9line Cazorla","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C\u00e9line Cazorla","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; French Regional Center for Tick-borne Diseases (CRMVT), Saint-Etienne University Hospital, Avenue Albert Raimond, 42270 Saint-Priest-en-Jarez, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; French Regional Center for Tick-borne Diseases (CRMVT), Saint-Etienne University Hospital, Avenue Albert Raimond, 42270 Saint-Priest-en-Jarez, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074533748","display_name":"Nazl\u0131 Ayhan","orcid":"https://orcid.org/0000-0003-4979-6794","observed_orcids":["https://orcid.org/0000-0003-4979-6794"]},"institutions":[{"id":"https://openalex.org/I4210087217","display_name":"M\u00e9diterran\u00e9e Infection Foundation","ror":"https://ror.org/0068ff141","country_code":"FR","type":"other","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087217","https://openalex.org/I4210087487"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nazli Ayhan","raw_affiliation_strings":["French National Reference Center for Arboviruses, IHU M\u00e9diterran\u00e9e-Infection 1er Etage - Laboratoire 114 19-21 Boulevard Jean Moulin, 13005 Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"French National Reference Center for Arboviruses, IHU M\u00e9diterran\u00e9e-Infection 1er Etage - Laboratoire 114 19-21 Boulevard Jean Moulin, 13005 Marseille, France","institution_ids":["https://openalex.org/I4210087217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017612741","display_name":"Laura Pezz\u0131","orcid":"https://orcid.org/0000-0001-7921-9221","observed_orcids":["https://orcid.org/0000-0001-7921-9221"]},"institutions":[{"id":"https://openalex.org/I4210087217","display_name":"M\u00e9diterran\u00e9e Infection Foundation","ror":"https://ror.org/0068ff141","country_code":"FR","type":"other","lineage":["https://openalex.org/I21491767","https://openalex.org/I4210087217","https://openalex.org/I4210087487"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Laura Pezzi","raw_affiliation_strings":["French National Reference Center for Arboviruses, IHU M\u00e9diterran\u00e9e-Infection 1er Etage - Laboratoire 114 19-21 Boulevard Jean Moulin, 13005 Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"French National Reference Center for Arboviruses, IHU M\u00e9diterran\u00e9e-Infection 1er Etage - Laboratoire 114 19-21 Boulevard Jean Moulin, 13005 Marseille, France","institution_ids":["https://openalex.org/I4210087217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056229196","display_name":"Anne Carricajo","orcid":"https://orcid.org/0000-0001-9530-4434","observed_orcids":["https://orcid.org/0000-0001-9530-4434"]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne Carricajo","raw_affiliation_strings":["Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":"https://orcid.org/0000-0001-9530-4434","affiliations":[{"raw_affiliation_string":"Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062351440","display_name":"M. Detoc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ma\u00eblle Detoc","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080412502","display_name":"Marie-France Lutz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-France Lutz","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114141404","display_name":"Anne Fresard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Anne Fr\u00e9sard","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062067490","display_name":"Martin Fayolle","orcid":"https://orcid.org/0000-0001-7778-6222","observed_orcids":["https://orcid.org/0000-0001-7778-6222"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I86767153","display_name":"Universit\u00e9 Jean Monnet","ror":"https://ror.org/04yznqr36","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I4405259976","https://openalex.org/I86767153"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Martin Fayolle","raw_affiliation_strings":["Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; CIRI - Centre International de Recherche en Infectiologie, Team GIMAP, Universit\u00e9 Jean Monnet, Universit\u00e9 de Lyon, Inserm, U1111, CNRS, UMR530, F42023 Saint-Etienne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; CIRI - Centre International de Recherche en Infectiologie, Team GIMAP, Universit\u00e9 Jean Monnet, Universit\u00e9 de Lyon, Inserm, U1111, CNRS, UMR530, F42023 Saint-Etienne, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210157006","https://openalex.org/I4210161906","https://openalex.org/I86767153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108176518","display_name":"Oulfa Boussetta-Charfi","orcid":"https://orcid.org/0009-0000-6544-2078","observed_orcids":["https://orcid.org/0009-0000-6544-2078"]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Oulfa Boussetta-Charfi","raw_affiliation_strings":["Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135429632","display_name":"Florent Rousset","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Florent Rousset","raw_affiliation_strings":["General Hospital of North Ard\u00e8che, 119 Rue du bon Pasteur, 07103 Annonay Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Hospital of North Ard\u00e8che, 119 Rue du bon Pasteur, 07103 Annonay Cedex, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135484797","display_name":"Fran\u00e7ois Ballereau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fran\u00e7ois Ballereau","raw_affiliation_strings":["General Hospital of Firminy, 2 rue Robert Ploton, 42704 Firminy, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Hospital of Firminy, 2 rue Robert Ploton, 42704 Firminy, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071542569","display_name":"Amandine Gagneux\u2010Brunon","orcid":"https://orcid.org/0000-0002-0892-2187","observed_orcids":["https://orcid.org/0000-0002-0892-2187"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I4405259976","display_name":"Universit\u00e9 Jean Monnet","ror":"https://ror.org/030bahv93","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I86767153","display_name":"Universit\u00e9 Jean Monnet","ror":"https://ror.org/04yznqr36","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I4405259976","https://openalex.org/I86767153"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Amandine Gagneux-Brunon","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; CIRI - Centre International de Recherche en Infectiologie, Team GIMAP, Universit\u00e9 Jean Monnet, Universit\u00e9 de Lyon, Inserm, U1111, CNRS, UMR530, F42023 Saint-Etienne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; CIRI - Centre International de Recherche en Infectiologie, Team GIMAP, Universit\u00e9 Jean Monnet, Universit\u00e9 de Lyon, Inserm, U1111, CNRS, UMR530, F42023 Saint-Etienne, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210157006","https://openalex.org/I4210161906","https://openalex.org/I4405259976","https://openalex.org/I86767153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001830388","display_name":"Jean\u2010Philippe Camdessanch\u00e9","orcid":"https://orcid.org/0000-0002-5282-6707","observed_orcids":["https://orcid.org/0000-0002-5282-6707"]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean-Philippe Camdessanch\u00e9","raw_affiliation_strings":["Neurology Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071997873","display_name":"Sylvie Pillet","orcid":"https://orcid.org/0000-0002-0882-3162","observed_orcids":["https://orcid.org/0000-0002-0882-3162"]},"institutions":[{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sylvie Pillet","raw_affiliation_strings":["Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Infectious Agents, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France","institution_ids":["https://openalex.org/I4210157006"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002560848","display_name":"\u00c9lisabeth Botelho-Nevers","orcid":"https://orcid.org/0000-0003-2773-7750","observed_orcids":["https://orcid.org/0000-0003-2773-7750"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210157006","display_name":"Centre Hospitalier Universitaire de Saint-\u00c9tienne","ror":"https://ror.org/04pn6vp43","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210157006"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I4405259976","display_name":"Universit\u00e9 Jean Monnet","ror":"https://ror.org/030bahv93","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I4405259976"]},{"id":"https://openalex.org/I86767153","display_name":"Universit\u00e9 Jean Monnet","ror":"https://ror.org/04yznqr36","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I4405259976","https://openalex.org/I86767153"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Elisabeth Botelho-Nevers","raw_affiliation_strings":["Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; French Regional Center for Tick-borne Diseases (CRMVT), Saint-Etienne University Hospital, Avenue Albert Raimond, 42270 Saint-Priest-en-Jarez, France; CIRI - Centre International de Recherche en Infectiologie, Team GIMAP, Universit\u00e9 Jean Monnet, Universit\u00e9 de Lyon, Inserm, U1111, CNRS, UMR530, F42023 Saint-Etienne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Diseases Department, Saint-Etienne University Hospital, 42055 Saint Etienne Cedex 02, France; French Regional Center for Tick-borne Diseases (CRMVT), Saint-Etienne University Hospital, Avenue Albert Raimond, 42270 Saint-Priest-en-Jarez, France; CIRI - Centre International de Recherche en Infectiologie, Team GIMAP, Universit\u00e9 Jean Monnet, Universit\u00e9 de Lyon, Inserm, U1111, CNRS, UMR530, F42023 Saint-Etienne, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210157006","https://openalex.org/I4210161906","https://openalex.org/I4405259976","https://openalex.org/I86767153"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210157006"],"apc_list":{"value":1640,"currency":"USD","value_usd":1640},"apc_paid":{"value":1640,"currency":"USD","value_usd":1640},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.25488969,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"56","issue":"4","first_page":"105281","last_page":"105281"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10296","display_name":"Vector-borne infectious diseases","score":0.9336000084877014,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":0.05350000038743019,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.006899999920278788,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tick-borne-encephalitis","display_name":"tick-borne encephalitis","score":1.0},{"id":"https://openalex.org/keywords/tick-borne-encephalitis-virus","display_name":"tick-borne encephalitis virus","score":0.9860000014305115},{"id":"https://openalex.org/keywords/encephalitis","display_name":"encephalitis","score":0.7749999761581421},{"id":"https://openalex.org/keywords/meningitis","display_name":"meningitis","score":0.699999988079071},{"id":"https://openalex.org/keywords/central-nervous-system-infection","display_name":"central nervous system infection","score":0.7639999985694885},{"id":"https://openalex.org/keywords/autochthonous-transmission","display_name":"autochthonous transmission","score":0.7990000247955322},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.5049999952316284},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-antibodies","display_name":"cerebrospinal fluid antibodies","score":0.7910000085830688},{"id":"https://openalex.org/keywords/varicella-zoster-virus","display_name":"varicella-zoster virus","score":0.8849999904632568},{"id":"https://openalex.org/keywords/herpes-simplex-virus","display_name":"herpes simplex virus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/disease-emergence","display_name":"disease emergence","score":0.5},{"id":"https://openalex.org/keywords/auvergne-rhone-alpes","display_name":"Auvergne-Rh\u00f4ne-Alpes","score":0.8640000224113464},{"id":"https://openalex.org/keywords/saint-etienne","display_name":"Saint-\u00c9tienne","score":0.8370000123977661},{"id":"https://openalex.org/keywords/delayed-diagnosis","display_name":"delayed diagnosis","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6859999895095825},{"id":"https://openalex.org/C83455156","wikidata":"https://www.wikidata.org/wiki/Q199615","display_name":"Encephalitis","level":3,"score":0.6830999851226807},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6606000065803528},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.48179998993873596},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.43149998784065247},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.43070000410079956},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.4146000146865845},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.38429999351501465},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.31779998540878296},{"id":"https://openalex.org/C2777704947","wikidata":"https://www.wikidata.org/wiki/Q551085","display_name":"Myelitis","level":3,"score":0.3125},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3109000027179718},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.28439998626708984},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C2986834420","wikidata":"https://www.wikidata.org/wiki/Q5932254","display_name":"Age groups","level":2,"score":0.2667999863624573},{"id":"https://openalex.org/C2779734145","wikidata":"https://www.wikidata.org/wiki/Q3053951","display_name":"Viral encephalitis","level":4,"score":0.2662000060081482},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.2506999969482422}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000914","descriptor_name":"Antibodies, Viral","qualifier_ui":"Q000134","qualifier_name":"cerebrospinal fluid","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004669","descriptor_name":"Encephalitis Viruses, Tick-Borne","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004669","descriptor_name":"Encephalitis Viruses, Tick-Borne","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004675","descriptor_name":"Encephalitis, Tick-Borne","qualifier_ui":"Q000134","qualifier_name":"cerebrospinal fluid","is_major_topic":true},{"descriptor_ui":"D004675","descriptor_name":"Encephalitis, Tick-Borne","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D004675","descriptor_name":"Encephalitis, Tick-Borne","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D004675","descriptor_name":"Encephalitis, Tick-Borne","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005602","descriptor_name":"France","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008590","descriptor_name":"Meningoencephalitis","qualifier_ui":"Q000134","qualifier_name":"cerebrospinal fluid","is_major_topic":true},{"descriptor_ui":"D008590","descriptor_name":"Meningoencephalitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008590","descriptor_name":"Meningoencephalitis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.idnow.2026.105281","doi":"https://doi.org/10.1016/j.idnow.2026.105281","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.idnow.2026.105281","pdf_url":null,"source":{"id":"https://openalex.org/S4210196242","display_name":"Infectious Diseases Now","issn_l":"2666-9919","issn":["2666-9919","2666-9927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infectious Diseases Now","raw_type":"journal-article"},{"id":"pmid:42086146","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42086146","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infectious diseases now","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05785789v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05785789","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Infectious Diseases Now, 2026, 56 (4), pp.105281. ⟨10.1016/j.idnow.2026.105281⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.idnow.2026.105281","doi":"https://doi.org/10.1016/j.idnow.2026.105281","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.idnow.2026.105281","pdf_url":null,"source":{"id":"https://openalex.org/S4210196242","display_name":"Infectious Diseases Now","issn_l":"2666-9919","issn":["2666-9919","2666-9927"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infectious Diseases Now","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G6666494529","display_name":null,"funder_award_id":"75556185","funder_id":"https://openalex.org/F4320307765","funder_display_name":"Pfizer"}],"funders":[{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F5986151379","display_name":"Pfizer France","ror":"https://ror.org/02c9yny10"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1514418800","https://openalex.org/W1983516658","https://openalex.org/W2009654491","https://openalex.org/W2030032381","https://openalex.org/W2088786559","https://openalex.org/W2117836991","https://openalex.org/W2127116682","https://openalex.org/W2326122211","https://openalex.org/W2328041195","https://openalex.org/W2604537852","https://openalex.org/W2606361893","https://openalex.org/W2741979174","https://openalex.org/W2759511478","https://openalex.org/W2810865753","https://openalex.org/W2971764439","https://openalex.org/W4200050735","https://openalex.org/W4220685925","https://openalex.org/W4226086951","https://openalex.org/W4281695951","https://openalex.org/W4308045508","https://openalex.org/W4327677484","https://openalex.org/W4327951981","https://openalex.org/W4385715764","https://openalex.org/W4387711203","https://openalex.org/W4389206906","https://openalex.org/W4402776381","https://openalex.org/W4403943504","https://openalex.org/W4408460860","https://openalex.org/W7123965947"],"related_works":["https://openalex.org/W2971764439","https://openalex.org/W4410811747","https://openalex.org/W2759511478","https://openalex.org/W7205396924","https://openalex.org/W2112044806","https://openalex.org/W2946385120","https://openalex.org/W2041631951","https://openalex.org/W2805384068","https://openalex.org/W7100500691","https://openalex.org/W3080701375"],"abstract_inverted_index":{"OBJECTIVES:":[0],"In":[1,188,231],"2017,":[2],"the":[3,14,31,49,120,137,171,189,193,213,217],"first":[4,172],"autochthonous":[5,208],"cases":[6,132,224],"of":[7,16,33,60,105,133,140,165,175],"tick-borne":[8],"encephalitis":[9],"(TBE)":[10],"were":[11],"reported":[12],"in":[13,23,37,206,212,240],"region":[15],"Saint-\u00c9tienne,":[17],"a":[18,126],"forested":[19],"and":[20,42,46,71,82,109,151,246],"mountainous":[21],"area":[22,39],"Auvergne-Rh\u00f4ne-Alpes":[24],"(AURA),":[25],"France.":[26],"We":[27,54,90,180],"aimed":[28],"to":[29,47,68,196,236],"describe":[30],"frequency":[32],"TBE":[34,51,100,234],"among":[35,170],"patients":[36,56,204,241],"this":[38],"with":[40,62,146,243],"acute":[41],"subacute":[43],"neurological":[44,63],"symptoms":[45,64],"characterize":[48],"confirmed":[50,115],"cases.":[52],"METHODS:":[53],"included":[55,122],"over":[57],"two":[58],"years":[59],"age":[61],"evolving":[65],"for":[66,97,162],"up":[67],"three":[69],"months":[70],"having":[72],"undergone":[73],"cerebrospinal":[74],"fluid":[75],"(CSF)":[76],"analysis":[77],"between":[78],"January":[79],"1,":[80],"2021":[81],"December":[83],"31,":[84],"2023":[85],"at":[86],"Saint-\u00c9tienne":[87],"University":[88],"Hospital.":[89],"retrospectively":[91,181],"analyzed":[92],"available":[93],"CSF":[94],"and/or":[95],"serum":[96],"antibodies":[98],"against":[99],"virus":[101,148,155],"(TBEV)":[102],"by":[103],"means":[104],"enzyme-linked":[106],"immunosorbent":[107],"assay":[108],"chemiluminescent":[110],"immunoassay,":[111],"respectively.":[112],"Seroneutralization":[113],"testing":[114],"positive":[116],"specimens.":[117],"RESULTS:":[118],"Among":[119],"544":[121],"patients,":[123],"84":[124],"had":[125],"nervous":[127,177],"system":[128,178],"infection,":[129],"including":[130,210],"seven":[131],"TBE.":[134],"TBEV":[135,158,168],"represented":[136],"second":[138],"cause":[139],"infectious":[141],"encephalitis/meningoencephalitis":[142],"(six":[143,149],"cases),":[144],"along":[145],"varicella-zoster":[147],"cases)":[150],"after":[152],"herpes":[153],"simplex":[154],"(seven":[156],"cases).":[157],"was":[159,198,222],"also":[160],"responsible":[161],"one":[163,183],"case":[164],"meningitis.":[166],"Overall,":[167],"ranked":[169],"five":[173],"causes":[174],"central":[176],"infection.":[179],"diagnosed":[182],"patient":[184],"through":[185],"systematic":[186],"screening.":[187],"remaining":[190],"six":[191],"cases,":[192],"median":[194],"time":[195],"diagnosis":[197],"23":[199],"days":[200],"(range":[201],"6-157).":[202],"All":[203],"lived":[205],"rural":[207],"areas,":[209],"four":[211],"Pilat":[214],"Massif,":[215],"where":[216],"estimated":[218],"annual":[219],"incidence":[220],"rate":[221],"13":[223],"per":[225],"100,000":[226],"inhabitants.":[227],"None":[228],"died.":[229],"CONCLUSIONS:":[230],"Western":[232],"AURA,":[233],"needs":[235],"be":[237,249],"systematically":[238],"screened":[239],"presenting":[242],"evocative":[244],"symptoms,":[245],"prevention":[247],"should":[248],"prioritized.":[250]},"counts_by_year":[],"updated_date":"2026-10-25T09:29:13.331239","created_date":"2026-05-07T00:00:00"}