{"id":"https://openalex.org/W7154408019","doi":"https://doi.org/10.70352/scrj.cr.25-0720","title":"Synchronous Double Primary Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: A Case Report","display_name":"Synchronous Double Primary Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: A Case Report","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7154408019","doi":"https://doi.org/10.70352/scrj.cr.25-0720","pmid":"https://pubmed.ncbi.nlm.nih.gov/42006675","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13086505"},"language":"en","primary_location":{"id":"doi:10.70352/scrj.cr.25-0720","doi":"https://doi.org/10.70352/scrj.cr.25-0720","is_oa":true,"landing_page_url":"https://doi.org/10.70352/scrj.cr.25-0720","pdf_url":"https://www.jstage.jst.go.jp/article/scrj/12/1/12_cr.25-0720/_pdf","source":{"id":"https://openalex.org/S2738567394","display_name":"Surgical Case Reports","issn_l":"2198-7793","issn":["2198-7793"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jstage.jst.go.jp/article/scrj/12/1/12_cr.25-0720/_pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159749333","display_name":"Takahiro Yoshimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takahiro Yoshimura","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020803603","display_name":"Hironori Hayashi","orcid":"https://orcid.org/0000-0002-7560-3354","observed_orcids":["https://orcid.org/0000-0002-7560-3354"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hironori Hayashi","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":"https://orcid.org/0000-0002-7560-3354","affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133590963","display_name":"Kazuki Kato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuki Kato","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024909467","display_name":"Shinichi Nakanuma","orcid":"https://orcid.org/0000-0002-5118-2225","observed_orcids":["https://orcid.org/0000-0002-5118-2225"]},"institutions":[{"id":"https://openalex.org/I4210104330","display_name":"Kanazawa University Hospital","ror":"https://ror.org/00xsdn005","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210104330"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinichi Nakanuma","raw_affiliation_strings":["Department of Hepato-biliary-pancreatic and Transplant Surgery, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepato-biliary-pancreatic and Transplant Surgery, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan","institution_ids":["https://openalex.org/I4210104330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003193101","display_name":"Yuichiro Furutani","orcid":"https://orcid.org/0000-0002-8258-9773","observed_orcids":["https://orcid.org/0000-0002-8258-9773"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichiro Furutani","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":"https://orcid.org/0000-0002-8258-9773","affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023149245","display_name":"Daisuke Fujimori","orcid":"https://orcid.org/0000-0003-3465-0477","observed_orcids":["https://orcid.org/0000-0003-3465-0477"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Daisuke Fujimori","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060152593","display_name":"Hiroki Kitabayashi","orcid":"https://orcid.org/0000-0003-3810-8095","observed_orcids":["https://orcid.org/0000-0003-3810-8095"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroki Kitabayashi","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003606058","display_name":"Koichiro Sawada","orcid":"https://orcid.org/0000-0001-9221-6420","observed_orcids":["https://orcid.org/0000-0001-9221-6420"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koichiro Sawada","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082936561","display_name":"Masanori Kotake","orcid":"https://orcid.org/0000-0002-4224-7680","observed_orcids":["https://orcid.org/0000-0002-4224-7680"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masanori Kotake","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":"https://orcid.org/0000-0002-4224-7680","affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112316592","display_name":"Kaeko Oyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaeko Oyama","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101068246","display_name":"Takuo HARA","orcid":"https://orcid.org/0009-0001-0877-6175","observed_orcids":["https://orcid.org/0009-0001-0877-6175"]},"institutions":[{"id":"https://openalex.org/I4210160901","display_name":"Kouseiren Takaoka Hospital","ror":"https://ror.org/05vchgv90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210160901"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takuo Hara","raw_affiliation_strings":["Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan"],"raw_orcid":"https://orcid.org/0009-0001-0877-6175","affiliations":[{"raw_affiliation_string":"Department of Surgery, Kouseiren Takaoka Hospital, Takaoka, Toyama, Japan","institution_ids":["https://openalex.org/I4210160901"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040080599","display_name":"Shintaro Yagi","orcid":"https://orcid.org/0000-0001-7465-5761","observed_orcids":["https://orcid.org/0000-0001-7465-5761"]},"institutions":[{"id":"https://openalex.org/I4210104330","display_name":"Kanazawa University Hospital","ror":"https://ror.org/00xsdn005","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210104330"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shintaro Yagi","raw_affiliation_strings":["Department of Hepato-biliary-pancreatic and Transplant Surgery, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan"],"raw_orcid":"https://orcid.org/0000-0001-7465-5761","affiliations":[{"raw_affiliation_string":"Department of Hepato-biliary-pancreatic and Transplant Surgery, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan","institution_ids":["https://openalex.org/I4210104330"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5020803603"],"corresponding_institution_ids":["https://openalex.org/I4210160901"],"apc_list":{"value":1535,"currency":"USD","value_usd":1535},"apc_paid":{"value":1535,"currency":"USD","value_usd":1535},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"12","issue":"1","first_page":"n/a","last_page":"n/a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.46389999985694885,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T14078","display_name":"Multiple and Secondary Primary Cancers","score":0.46389999985694885,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.2847000062465668,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11364","display_name":"Cholangiocarcinoma and Gallbladder Cancer Studies","score":0.13169999420642853,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9359999895095825},{"id":"https://openalex.org/keywords/intrahepatic-cholangiocarcinoma","display_name":"intrahepatic cholangiocarcinoma","score":1.0},{"id":"https://openalex.org/keywords/left-hepatectomy","display_name":"left hepatectomy","score":0.8209999799728394},{"id":"https://openalex.org/keywords/regional-lymph-node-dissection","display_name":"regional lymph node dissection","score":0.9300000071525574},{"id":"https://openalex.org/keywords/cholecystectomy","display_name":"cholecystectomy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/ca19-9","display_name":"CA19-9","score":0.953000009059906},{"id":"https://openalex.org/keywords/des-gamma-carboxy-prothrombin","display_name":"PIVKA-II","score":0.9129999876022339},{"id":"https://openalex.org/keywords/hepatitis-c-virus","display_name":"hepatitis C virus","score":0.6290000081062317},{"id":"https://openalex.org/keywords/alcohol-consumption","display_name":"alcohol consumption","score":0.5540000200271606},{"id":"https://openalex.org/keywords/chronic-liver-disease","display_name":"chronic liver disease","score":0.7099999785423279},{"id":"https://openalex.org/keywords/preoperative-diagnosis","display_name":"preoperative diagnosis","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7804999947547913},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7111999988555908},{"id":"https://openalex.org/C2777977315","wikidata":"https://www.wikidata.org/wiki/Q7243056","display_name":"Primary (astronomy)","level":2,"score":0.4034000039100647},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3882000148296356},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3425000011920929},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3328999876976013},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.31279999017715454},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.30889999866485596},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.287200003862381},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.28380000591278076},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.26170000433921814}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.70352/scrj.cr.25-0720","doi":"https://doi.org/10.70352/scrj.cr.25-0720","is_oa":true,"landing_page_url":"https://doi.org/10.70352/scrj.cr.25-0720","pdf_url":"https://www.jstage.jst.go.jp/article/scrj/12/1/12_cr.25-0720/_pdf","source":{"id":"https://openalex.org/S2738567394","display_name":"Surgical Case Reports","issn_l":"2198-7793","issn":["2198-7793"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13086505","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13086505/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13086505/pdf/scr-12-01-25-0720.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surg Case Rep","raw_type":"Text"},{"id":"pmid:42006675","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42006675","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical case reports","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.70352/scrj.cr.25-0720","doi":"https://doi.org/10.70352/scrj.cr.25-0720","is_oa":true,"landing_page_url":"https://doi.org/10.70352/scrj.cr.25-0720","pdf_url":"https://www.jstage.jst.go.jp/article/scrj/12/1/12_cr.25-0720/_pdf","source":{"id":"https://openalex.org/S2738567394","display_name":"Surgical Case Reports","issn_l":"2198-7793","issn":["2198-7793"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgical Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7154408019.pdf","grobid_xml":"https://content.openalex.org/works/W7154408019.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1895232916","https://openalex.org/W1947004237","https://openalex.org/W2016937738","https://openalex.org/W2017809655","https://openalex.org/W2037680028","https://openalex.org/W2090357861","https://openalex.org/W2149066190","https://openalex.org/W2155043559","https://openalex.org/W2228046629","https://openalex.org/W2589068086","https://openalex.org/W4205287974","https://openalex.org/W4309236284","https://openalex.org/W4360858615","https://openalex.org/W4365150249","https://openalex.org/W4409497226"],"related_works":["https://openalex.org/W2140365948","https://openalex.org/W3179992643","https://openalex.org/W2513705031","https://openalex.org/W2269864088","https://openalex.org/W4393857829","https://openalex.org/W7207944861","https://openalex.org/W4402277882","https://openalex.org/W3116806378","https://openalex.org/W2886801286","https://openalex.org/W2471837545"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Hepatocellular":[1],"carcinoma":[2],"(HCC)":[3],"and":[4,12,92,100,107,129,145,161,163,171,188],"intrahepatic":[5],"cholangiocarcinoma":[6],"(iCCA)":[7],"are":[8,175],"the":[9,27,38,66,135],"most":[10,14],"common":[11,15],"second":[13],"primary":[16,23],"liver":[17,51,70,84,182],"cancers,":[18],"respectively.":[19,110],"In":[20],"contrast,":[21],"double":[22],"hepatic":[24],"cancer":[25],"(DPHC),":[26],"synchronous":[28],"occurrence":[29],"of":[30,37,49,68],"these":[31],"two":[32,114],"tumors":[33,183],"in":[34,45,57,121,127,143,147],"different":[35,118],"locations":[36],"liver,":[39],"is":[40],"an":[41,152],"uncommon":[42],"pathology,":[43],"occurring":[44],"less":[46],"than":[47],"0.8%":[48],"all":[50],"malignancies.":[52],"CASE":[53],"PRESENTATION:":[54],"A":[55],"man":[56],"his":[58],"70s":[59],"was":[60,138,165],"referred":[61],"to":[62,87],"our":[63],"department":[64],"for":[65,82,177],"treatment":[67],"multiple":[69,181],"tumors.":[71],"He":[72],"had":[73],"previously":[74],"been":[75],"treated":[76],"with":[77,117,141,156,180],"a":[78],"direct-acting":[79],"antiviral":[80],"agent":[81],"chronic":[83],"disease":[85],"due":[86],"hepatitis":[88],"C":[89],"virus":[90],"infection":[91],"alcohol":[93],"consumption.":[94],"His":[95],"carbohydrate":[96],"antigen":[97],"19-9":[98],"(CA19-9)":[99],"des-\u03b3-carboxy":[101],"prothrombin":[102],"levels":[103],"were":[104],"36058":[105],"U/mL":[106],"159":[108],"mAU/mL,":[109],"Imaging":[111],"studies":[112],"revealed":[113],"separate":[115],"lesions":[116],"contrast":[119],"features":[120,187],"segments":[122],"VIII":[123],"(SVIII,":[124],"2.5":[125],"cm":[126],"size)":[128],"IV/II/III":[130],"(SIV/II/III,":[131],"3.5":[132],"cm).":[133],"Therefore,":[134],"preoperative":[136],"diagnosis":[137],"DPHC,":[139],"consistent":[140],"HCC":[142],"SVIII":[144],"iCCA":[146],"SIV/II/III.":[148],"The":[149],"patient":[150],"underwent":[151],"extended":[153],"left":[154],"hemihepatectomy":[155],"regional":[157],"lymph":[158],"node":[159],"dissection":[160],"cholecystectomy,":[162],"DPHC":[164],"confirmed":[166],"histologically.":[167],"CONCLUSIONS:":[168],"Accurate":[169],"diagnoses":[170],"appropriate":[172],"therapeutic":[173],"strategies":[174],"essential":[176],"patients":[178],"presenting":[179],"showing":[184],"heterogeneous":[185],"imaging":[186],"elevated":[189],"CA19-9":[190],"levels.":[191]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-04-15T00:00:00"}