{"id":"https://openalex.org/W7153175603","doi":"https://doi.org/10.1002/clc.70278","title":"Updated Meta\u2010Analysis of Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Conduction System Disorders: Insights From New Evidence","display_name":"Updated Meta\u2010Analysis of Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Conduction System Disorders: Insights From New Evidence","publication_year":2026,"publication_date":"2026-04-01","ids":{"openalex":"https://openalex.org/W7153175603","doi":"https://doi.org/10.1002/clc.70278","pmid":"https://pubmed.ncbi.nlm.nih.gov/41957548"},"language":"en","primary_location":{"id":"doi:10.1002/clc.70278","doi":"https://doi.org/10.1002/clc.70278","is_oa":true,"landing_page_url":"https://doi.org/10.1002/clc.70278","pdf_url":null,"source":{"id":"https://openalex.org/S82037729","display_name":"Clinical Cardiology","issn_l":"0160-9289","issn":["0160-9289","1932-8737"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1002/clc.70278","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5117511737","display_name":"Rehan Ishaque","orcid":"https://orcid.org/0009-0009-5197-444X","observed_orcids":["https://orcid.org/0009-0009-5197-444X"]},"institutions":[{"id":"https://openalex.org/I1318157472","display_name":"Liaquat University of Medical & Health Sciences","ror":"https://ror.org/015jxh185","country_code":"PK","type":"education","lineage":["https://openalex.org/I1318157472"]}],"countries":["PK"],"is_corresponding":true,"raw_author_name":"Rehan Ishaque","raw_affiliation_strings":["Internal Medicine Liaquat University of Medical Health &amp; Sciences Jamshoro Pakistan"],"raw_orcid":"https://orcid.org/0009-0009-5197-444X","affiliations":[{"raw_affiliation_string":"Internal Medicine Liaquat University of Medical Health &amp; Sciences Jamshoro Pakistan","institution_ids":["https://openalex.org/I1318157472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010534951","display_name":"George S. Abela","orcid":"https://orcid.org/0000-0002-8201-956X","observed_orcids":["https://orcid.org/0000-0002-8201-956X"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George S. Abela","raw_affiliation_strings":["Michigan State University Lansing Michigan USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University Lansing Michigan USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099162475","display_name":"Ghazal Ishaque","orcid":"https://orcid.org/0009-0004-7800-1828","observed_orcids":["https://orcid.org/0009-0004-7800-1828"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ghazal Ishaque","raw_affiliation_strings":["Shaheed Mohtarma Benazir Bhutto Medical College Karachi Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaheed Mohtarma Benazir Bhutto Medical College Karachi Pakistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000658168","display_name":"Amina Akram","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amina Akram","raw_affiliation_strings":["Mayo Clinic Rochester Rochester Minnesota USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester Rochester Minnesota USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120586646","display_name":"Fnu Reya","orcid":"https://orcid.org/0009-0007-8768-1943","observed_orcids":["https://orcid.org/0009-0007-8768-1943"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. N. U. Reya","raw_affiliation_strings":["Ghulam Muhammad Mahar Medical College Sukkur Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ghulam Muhammad Mahar Medical College Sukkur Pakistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5146834757","display_name":"Furqan Tarique Memon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1318157472","display_name":"Liaquat University of Medical & Health Sciences","ror":"https://ror.org/015jxh185","country_code":"PK","type":"education","lineage":["https://openalex.org/I1318157472"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Furqan Tarique Memon","raw_affiliation_strings":["Internal Medicine Liaquat University of Medical Health &amp; Sciences Jamshoro Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Internal Medicine Liaquat University of Medical Health &amp; Sciences Jamshoro Pakistan","institution_ids":["https://openalex.org/I1318157472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107068616","display_name":"Hamza Ali Danish","orcid":"https://orcid.org/0009-0009-7271-281X","observed_orcids":["https://orcid.org/0009-0009-7271-281X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hamza Danish","raw_affiliation_strings":["FFCA South High School Calgary Alberta Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"FFCA South High School Calgary Alberta Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5127960658","display_name":"Amna Ikram","orcid":"https://orcid.org/0009-0002-3072-1987","observed_orcids":["https://orcid.org/0009-0002-3072-1987"]},"institutions":[{"id":"https://openalex.org/I176884743","display_name":"Fatima Jinnah Medical University","ror":"https://ror.org/051cp7s36","country_code":"PK","type":"education","lineage":["https://openalex.org/I176884743"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Amna Ikram","raw_affiliation_strings":["Fatima Jinnah Medical University Lahore Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fatima Jinnah Medical University Lahore Pakistan","institution_ids":["https://openalex.org/I176884743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072457239","display_name":"Zulfiqar Qutrio Baloch","orcid":"https://orcid.org/0000-0001-5557-1052","observed_orcids":["https://orcid.org/0000-0001-5557-1052"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zulfiqar Qutrio Baloch","raw_affiliation_strings":["St. Francis Hospital Bartlett Bartlett Tennessee USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Francis Hospital Bartlett Bartlett Tennessee USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113951321","display_name":"Supratik Rayamajhi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Supratik Rayamajhi","raw_affiliation_strings":["Michigan State University Lansing Michigan USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University Lansing Michigan USA","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5117511737"],"corresponding_institution_ids":["https://openalex.org/I1318157472"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":{"value":3810,"currency":"USD","value_usd":3810},"fwci":9.1463,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.97495871,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"49","issue":"4","first_page":"e70278","last_page":"e70278"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/left-bundle-branch-area-pacing","display_name":"left bundle branch area pacing","score":0.9980000257492065},{"id":"https://openalex.org/keywords/right-ventricular-pacing","display_name":"right ventricular pacing","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bradycardia","display_name":"bradycardia","score":0.8519999980926514},{"id":"https://openalex.org/keywords/pacemaker-implantation","display_name":"pacemaker implantation","score":0.8809999823570251},{"id":"https://openalex.org/keywords/qrs-duration","display_name":"QRS duration","score":0.8360000252723694},{"id":"https://openalex.org/keywords/cardiac-remodeling","display_name":"cardiac remodeling","score":0.7070000171661377},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.9470000267028809},{"id":"https://openalex.org/keywords/heart-failure-hospitalization","display_name":"heart failure hospitalization","score":0.8970000147819519},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.9879999756813049},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.9710000157356262},{"id":"https://openalex.org/keywords/ventricular-dyssynchrony","display_name":"ventricular dyssynchrony","score":0.9359999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9678999781608582},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7488999962806702},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7245000004768372},{"id":"https://openalex.org/C3020135794","wikidata":"https://www.wikidata.org/wiki/Q372713","display_name":"Ventricular pacing","level":3,"score":0.7099999785423279},{"id":"https://openalex.org/C2778134712","wikidata":"https://www.wikidata.org/wiki/Q1047307","display_name":"Bundle","level":2,"score":0.5411999821662903},{"id":"https://openalex.org/C2992910135","wikidata":"https://www.wikidata.org/wiki/Q372713","display_name":"Cardiac pacing","level":2,"score":0.47269999980926514},{"id":"https://openalex.org/C2777632367","wikidata":"https://www.wikidata.org/wiki/Q18379371","display_name":"Bundle branches","level":4,"score":0.4357999861240387},{"id":"https://openalex.org/C2777473070","wikidata":"https://www.wikidata.org/wiki/Q2143688","display_name":"Left bundle branch block","level":3,"score":0.4115999937057495},{"id":"https://openalex.org/C104397207","wikidata":"https://www.wikidata.org/wiki/Q72711","display_name":"Electrical conduction system of the heart","level":3,"score":0.4065000116825104},{"id":"https://openalex.org/C2776034619","wikidata":"https://www.wikidata.org/wiki/Q3428020","display_name":"Cardiac resynchronization therapy","level":4,"score":0.36890000104904175},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.36340001225471497},{"id":"https://openalex.org/C2777233412","wikidata":"https://www.wikidata.org/wiki/Q13365162","display_name":"Bundle branch block","level":3,"score":0.3156000077724457},{"id":"https://openalex.org/C2909456097","wikidata":"https://www.wikidata.org/wiki/Q189331","display_name":"Conduction abnormalities","level":2,"score":0.30660000443458557},{"id":"https://openalex.org/C2993376042","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricular function","level":2,"score":0.30570000410079956},{"id":"https://openalex.org/C2779731873","wikidata":"https://www.wikidata.org/wiki/Q1577202","display_name":"Bundle of His","level":4,"score":0.3034000098705292},{"id":"https://openalex.org/C523008124","wikidata":"https://www.wikidata.org/wiki/Q5357996","display_name":"Electrodiagnosis","level":2,"score":0.2858000099658966},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2768000066280365},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.259799987077713},{"id":"https://openalex.org/C2776719672","wikidata":"https://www.wikidata.org/wiki/Q17098435","display_name":"Left and right","level":2,"score":0.2558000087738037}],"mesh":[{"descriptor_ui":"D001919","descriptor_name":"Bradycardia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001919","descriptor_name":"Bradycardia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001919","descriptor_name":"Bradycardia","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001919","descriptor_name":"Bradycardia","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002036","descriptor_name":"Bundle of His","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002304","descriptor_name":"Cardiac Pacing, Artificial","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016278","descriptor_name":"Ventricular Function, Right","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020257","descriptor_name":"Ventricular Remodeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/clc.70278","doi":"https://doi.org/10.1002/clc.70278","is_oa":true,"landing_page_url":"https://doi.org/10.1002/clc.70278","pdf_url":null,"source":{"id":"https://openalex.org/S82037729","display_name":"Clinical Cardiology","issn_l":"0160-9289","issn":["0160-9289","1932-8737"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Cardiology","raw_type":"journal-article"},{"id":"pmid:41957548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41957548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13065497","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41957548/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13065497/pdf/CLC-49-e70278.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clin Cardiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/clc.70278","doi":"https://doi.org/10.1002/clc.70278","is_oa":true,"landing_page_url":"https://doi.org/10.1002/clc.70278","pdf_url":null,"source":{"id":"https://openalex.org/S82037729","display_name":"Clinical Cardiology","issn_l":"0160-9289","issn":["0160-9289","1932-8737"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.509353756904602,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1599507649","https://openalex.org/W1953024465","https://openalex.org/W2095437242","https://openalex.org/W2116475791","https://openalex.org/W2157823046","https://openalex.org/W2170892587","https://openalex.org/W2560438049","https://openalex.org/W2592082180","https://openalex.org/W2897070700","https://openalex.org/W2901841930","https://openalex.org/W2915867474","https://openalex.org/W2950663995","https://openalex.org/W2970684805","https://openalex.org/W2981699072","https://openalex.org/W2991619001","https://openalex.org/W2998912021","https://openalex.org/W3031391904","https://openalex.org/W3080892427","https://openalex.org/W3094515682","https://openalex.org/W3115826734","https://openalex.org/W3118615836","https://openalex.org/W3133979046","https://openalex.org/W3161719040","https://openalex.org/W3182611117","https://openalex.org/W3197191489","https://openalex.org/W3209421749","https://openalex.org/W3217414158","https://openalex.org/W3217576295","https://openalex.org/W3217587719","https://openalex.org/W4210365252","https://openalex.org/W4213094550","https://openalex.org/W4220982679","https://openalex.org/W4224256381","https://openalex.org/W4225159411","https://openalex.org/W4225406271","https://openalex.org/W4280653840","https://openalex.org/W4283458225","https://openalex.org/W4296353551","https://openalex.org/W4323654750","https://openalex.org/W4386022768","https://openalex.org/W4386226754","https://openalex.org/W4386418661","https://openalex.org/W4388455585","https://openalex.org/W4388769555","https://openalex.org/W4388783352","https://openalex.org/W4390198196","https://openalex.org/W4394841791","https://openalex.org/W4396707093","https://openalex.org/W4401083120","https://openalex.org/W4402071257","https://openalex.org/W4402552041","https://openalex.org/W4403861002","https://openalex.org/W4406116153","https://openalex.org/W4406347979","https://openalex.org/W4408547489","https://openalex.org/W4408957188","https://openalex.org/W4409619419"],"related_works":[],"abstract_inverted_index":{"INTRODUCTION:":[0],"Right":[1],"ventricular":[2,16,147,168],"pacing":[3,23,36],"(RVP)":[4],"has":[5],"long":[6],"been":[7],"the":[8,27,48],"standard":[9],"therapy":[10],"for":[11,73],"bradyarrhythmias":[12],"but":[13],"may":[14],"induce":[15],"dyssynchrony":[17],"and":[18,51,71,83,163,204,232],"adverse":[19],"cardiac":[20,230],"remodeling.":[21],"Physiologic":[22],"strategies":[24],"that":[25],"preserve":[26],"native":[28],"conduction":[29],"system,":[30],"particularly":[31],"left":[32,146,167],"bundle":[33],"branch":[34],"area":[35],"(LBBAP),":[37],"have":[38],"emerged":[39],"as":[40],"promising":[41],"alternatives.":[42],"This":[43],"study":[44],"aimed":[45],"to":[46,132,182],"evaluate":[47],"comparative":[49],"efficacy":[50],"safety":[52,244],"of":[53,102],"LBBAP":[54,82,110,188,224],"versus":[55],"RVP":[56,84,120],"through":[57,77],"an":[58],"updated":[59],"meta-analysis.":[60],"METHODS:":[61],"Following":[62],"PRISMA":[63],"guidelines,":[64],"we":[65],"systematically":[66],"searched":[67],"PubMed,":[68],"Cochrane":[69],"CENTRAL,":[70],"ClinicalTrials.gov":[72],"relevant":[74],"studies":[75,104],"published":[76],"June":[78],"2025.":[79],"Studies":[80],"comparing":[81],"in":[85,145,166,220],"patients":[86,107],"undergoing":[87],"pacemaker":[88],"implantation":[89],"were":[90,94,108],"included.":[91,109],"Pooled":[92],"estimates":[93],"calculated":[95],"using":[96],"random-effects":[97],"models.":[98],"RESULTS:":[99],"A":[100],"total":[101],"40":[103],"comprising":[105],"8290":[106],"was":[111,189],"associated":[112,190],"with":[113,119,142,191,217,237],"significantly":[114],"shorter":[115],"QRS":[116],"duration":[117],"compared":[118,236],"(30":[121],"studies,":[122,151,172],"n":[123,152,173],"=":[124,153,174],"5510;":[125],"MD":[126,155,176],"-35.56":[127],"ms,":[128],"95%":[129,157,179,198,210],"CI":[130,158,180,199,211],"-41.88":[131],"-29.24;":[133],"p":[134,160,184,201,213],"<":[135,161,185,202,214],"0.0001).":[136,186],"Structural":[137],"remodeling":[138],"also":[139],"favored":[140],"LBBAP,":[141],"greater":[143,164,218],"improvement":[144],"ejection":[148],"fraction":[149],"(16":[150],"1693;":[154],"+3.77%,":[156],"2.43-5.12;":[159],"0.0001)":[162,203],"reduction":[165,219],"end-diastolic":[169],"diameter":[170],"(13":[171],"1666;":[175],"-2.33":[177],"mm,":[178],"-3.59":[181],"-1.07;":[183],"Clinically,":[187],"lower":[192],"heart":[193],"failure":[194],"hospitalization":[195],"(RR":[196,208],"0.38,":[197],"0.29-0.52;":[200],"reduced":[205],"all-cause":[206],"mortality":[207],"0.55,":[209],"0.41-0.72;":[212],"0.0001),":[215],"along":[216],"NT-proBNP":[221],"levels.":[222],"CONCLUSION:":[223],"provides":[225],"superior":[226],"electrical":[227],"synchrony,":[228],"improved":[229],"remodeling,":[231],"favorable":[233],"clinical":[234],"outcomes":[235],"RVP,":[238],"while":[239],"maintaining":[240],"a":[241],"comparable":[242],"procedural":[243],"profile.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2026-04-11T00:00:00"}