{"id":"https://openalex.org/W7151806367","doi":"https://doi.org/10.1016/j.devcel.2026.03.007","title":"Active wetting and mechanics of collective cancer invasion","display_name":"Active wetting and mechanics of collective cancer invasion","publication_year":2026,"publication_date":"2026-04-01","ids":{"openalex":"https://openalex.org/W7151806367","doi":"https://doi.org/10.1016/j.devcel.2026.03.007","pmid":"https://pubmed.ncbi.nlm.nih.gov/41956078"},"language":"en","primary_location":{"id":"doi:10.1016/j.devcel.2026.03.007","doi":"https://doi.org/10.1016/j.devcel.2026.03.007","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.devcel.2026.03.007","pdf_url":null,"source":{"id":"https://openalex.org/S83804233","display_name":"Developmental Cell","issn_l":"1534-5807","issn":["1534-5807","1878-1551"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004199608","display_name":"Virangika K. Wimalasena","orcid":"https://orcid.org/0000-0002-1061-3439","observed_orcids":["https://orcid.org/0000-0002-1061-3439"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Virangika K. Wimalasena","raw_affiliation_strings":["Department of Cell Biology, John Hopkins University School of Medicine, Baltimore, MD, USA; Giovanis Institute for Translational Cell Biology, John Hopkins Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, John Hopkins University School of Medicine, Baltimore, MD, USA; Giovanis Institute for Translational Cell Biology, John Hopkins Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084041667","display_name":"Andrew J. Ewald","orcid":"https://orcid.org/0000-0002-1964-0740","observed_orcids":["https://orcid.org/0000-0002-1964-0740"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]},{"id":"https://openalex.org/I4210164401","display_name":"Sidney Kimmel Comprehensive Cancer Center","ror":"https://ror.org/05m5b8x20","country_code":"US","type":"facility","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Andrew J. Ewald","raw_affiliation_strings":["Department of Cell Biology, John Hopkins University School of Medicine, Baltimore, MD, USA; Giovanis Institute for Translational Cell Biology, John Hopkins Medicine, Baltimore, MD, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA. Electronic address: andrew.ewald@jhmi.edu"],"raw_orcid":"https://orcid.org/0000-0002-1964-0740","affiliations":[{"raw_affiliation_string":"Department of Cell Biology, John Hopkins University School of Medicine, Baltimore, MD, USA; Giovanis Institute for Translational Cell Biology, John Hopkins Medicine, Baltimore, MD, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA. Electronic address: andrew.ewald@jhmi.edu","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5084041667"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436","https://openalex.org/I4210164401"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.19862605,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"61","issue":"4","first_page":"716","last_page":"717"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.6859999895095825},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.7059999704360962},{"id":"https://openalex.org/keywords/mesothelium","display_name":"mesothelium","score":0.7739999890327454},{"id":"https://openalex.org/keywords/apical-constriction","display_name":"apical constriction","score":0.8209999799728394},{"id":"https://openalex.org/keywords/mesothelial-cells","display_name":"mesothelial cells","score":0.8550000190734863},{"id":"https://openalex.org/keywords/integrin-mediated-cell-adhesion","display_name":"integrin-mediated adhesion","score":0.8920000195503235},{"id":"https://openalex.org/keywords/cell-mechanics","display_name":"cell mechanics","score":0.828000009059906},{"id":"https://openalex.org/keywords/cell-spheroids","display_name":"cell spheroids","score":0.6669999957084656},{"id":"https://openalex.org/keywords/collective-invasion","display_name":"collective invasion","score":0.6309999823570251},{"id":"https://openalex.org/keywords/computational-modeling","display_name":"computational modeling","score":0.7369999885559082}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8251000046730042},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5508000254631042},{"id":"https://openalex.org/C134514944","wikidata":"https://www.wikidata.org/wiki/Q817136","display_name":"Wetting","level":2,"score":0.531000018119812},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.41749998927116394},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.36160001158714294},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.33169999718666077},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3027999997138977},{"id":"https://openalex.org/C25057246","wikidata":"https://www.wikidata.org/wiki/Q1344441","display_name":"Molecular mechanics","level":3,"score":0.27730000019073486},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2685000002384186},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.2551000118255615}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004848","descriptor_name":"Epithelium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016023","descriptor_name":"Integrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.devcel.2026.03.007","doi":"https://doi.org/10.1016/j.devcel.2026.03.007","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.devcel.2026.03.007","pdf_url":null,"source":{"id":"https://openalex.org/S83804233","display_name":"Developmental Cell","issn_l":"1534-5807","issn":["1534-5807","1878-1551"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Cell","raw_type":"journal-article"},{"id":"pmid:41956078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41956078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental cell","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2012376126","https://openalex.org/W2069202441","https://openalex.org/W2080098793","https://openalex.org/W2143468862","https://openalex.org/W2793869193","https://openalex.org/W2887832628","https://openalex.org/W3043396041","https://openalex.org/W3099564404","https://openalex.org/W7133506050"],"related_works":["https://openalex.org/W2154480504","https://openalex.org/W7133506050","https://openalex.org/W3014912136","https://openalex.org/W2137750805","https://openalex.org/W7098218409","https://openalex.org/W1996604878","https://openalex.org/W2462879242","https://openalex.org/W2391826686","https://openalex.org/W2078354424","https://openalex.org/W2269417541"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-04-09T00:00:00"}