{"id":"https://openalex.org/W7148890739","doi":"https://doi.org/10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","title":"Epigenetic regulation of transcription from genes-containing heterochromatin","display_name":"Epigenetic regulation of transcription from genes-containing heterochromatin","publication_year":2019,"publication_date":"2019-09-26","ids":{"openalex":"https://openalex.org/W7148890739","doi":"https://doi.org/10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","mag":"2983745184"},"language":"fr","primary_location":{"id":"doi:10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","doi":"https://doi.org/10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","is_oa":false,"landing_page_url":"https://doi.org/10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universit\u00e9 Paris-Saclay (ComUE)","raw_type":"dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085987025","display_name":"Yassir Idir","orcid":"https://orcid.org/0000-0002-4406-8889","observed_orcids":["https://orcid.org/0000-0002-4406-8889"]},"institutions":[{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Yassir Idir","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay (ComUE)"],"raw_orcid":"https://orcid.org/0000-0002-4406-8889","affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay (ComUE)","institution_ids":["https://openalex.org/I277688954"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085987025"],"corresponding_institution_ids":["https://openalex.org/I277688954"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.03229999914765358,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.010499999858438969,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetic-regulation-of-transcription","display_name":"epigenetic regulation of transcription","score":0.8610000014305115},{"id":"https://openalex.org/keywords/heterochromatin","display_name":"heterochromatin","score":0.9509999752044678},{"id":"https://openalex.org/keywords/polyadenylation","display_name":"polyadenylation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/bah-domain","display_name":"BAH domain","score":0.8700000047683716},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8289999961853027},{"id":"https://openalex.org/keywords/fpa","display_name":"FPA","score":0.6110000014305115},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.5860000252723694},{"id":"https://openalex.org/keywords/suppressor-screen","display_name":"suppressor screen","score":0.6169999837875366},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.4519999921321869},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6438999772071838},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6207000017166138},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4293999969959259},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3939000070095062},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.2721000015735626},{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.2694999873638153},{"id":"https://openalex.org/C64350747","wikidata":"https://www.wikidata.org/wiki/Q15334993","display_name":"RNA polymerase II","level":5,"score":0.26109999418258667},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.241799995303154},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.23680000007152557},{"id":"https://openalex.org/C103435993","wikidata":"https://www.wikidata.org/wiki/Q837783","display_name":"Heterochromatin","level":4,"score":0.23420000076293945}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","doi":"https://doi.org/10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","is_oa":false,"landing_page_url":"https://doi.org/10.70675/44dfd2d8za3f1z4d2azb17az7b325385be3b","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universit\u00e9 Paris-Saclay (ComUE)","raw_type":"dissertation"},{"id":"pmh:2019SACLS270","doi":null,"is_oa":false,"landing_page_url":"http://www.theses.fr/2019SACLS270","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},{"id":"mag:2983745184","doi":null,"is_oa":false,"landing_page_url":"http://www.theses.fr/2019SACLS270","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":198,"referenced_works":["https://openalex.org/W80785119","https://openalex.org/W1413417492","https://openalex.org/W1500546683","https://openalex.org/W1550720320","https://openalex.org/W1558207160","https://openalex.org/W1586021010","https://openalex.org/W1659768997","https://openalex.org/W1678624296","https://openalex.org/W1734091752","https://openalex.org/W1779683016","https://openalex.org/W1847567693","https://openalex.org/W1851394852","https://openalex.org/W1965368044","https://openalex.org/W1966077676","https://openalex.org/W1967817540","https://openalex.org/W1968466047","https://openalex.org/W1969092339","https://openalex.org/W1971895280","https://openalex.org/W1975746577","https://openalex.org/W1976702683","https://openalex.org/W1977995427","https://openalex.org/W1979117824","https://openalex.org/W1979846192","https://openalex.org/W1980436308","https://openalex.org/W1980593396","https://openalex.org/W1982409009","https://openalex.org/W1984891757","https://openalex.org/W1985267020","https://openalex.org/W1989416547","https://openalex.org/W1989687867","https://openalex.org/W1989794161","https://openalex.org/W1991269963","https://openalex.org/W1992313711","https://openalex.org/W1992353329","https://openalex.org/W2000365513","https://openalex.org/W2002377333","https://openalex.org/W2005531417","https://openalex.org/W2009692914","https://openalex.org/W2009909408","https://openalex.org/W2013571070","https://openalex.org/W2015132841","https://openalex.org/W2015705530","https://openalex.org/W2016246105","https://openalex.org/W2016813268","https://openalex.org/W2022400526","https://openalex.org/W2024171394","https://openalex.org/W2025040226","https://openalex.org/W2025538022","https://openalex.org/W2025553576","https://openalex.org/W2025604175","https://openalex.org/W2026343134","https://openalex.org/W2029979788","https://openalex.org/W2030593666","https://openalex.org/W2033616346","https://openalex.org/W2033629869","https://openalex.org/W2036247984","https://openalex.org/W2039995816","https://openalex.org/W2041389660","https://openalex.org/W2041793621","https://openalex.org/W2043405255","https://openalex.org/W2044231545","https://openalex.org/W2044627216","https://openalex.org/W2049872649","https://openalex.org/W2050125027","https://openalex.org/W2051541780","https://openalex.org/W2052974346","https://openalex.org/W2053317015","https://openalex.org/W2056335478","https://openalex.org/W2056542389","https://openalex.org/W2056633591","https://openalex.org/W2058306179","https://openalex.org/W2059864757","https://openalex.org/W2059979506","https://openalex.org/W2061538357","https://openalex.org/W2062771530","https://openalex.org/W2064228043","https://openalex.org/W2064489231","https://openalex.org/W2065046606","https://openalex.org/W2065064903","https://openalex.org/W2067528611","https://openalex.org/W2068634134","https://openalex.org/W2069904036","https://openalex.org/W2072572255","https://openalex.org/W2073764626","https://openalex.org/W2075942120","https://openalex.org/W2080326437","https://openalex.org/W2081204899","https://openalex.org/W2081468353","https://openalex.org/W2082491940","https://openalex.org/W2082694471","https://openalex.org/W2083196263","https://openalex.org/W2084885369","https://openalex.org/W2085154635","https://openalex.org/W2088998472","https://openalex.org/W2089832295","https://openalex.org/W2091722627","https://openalex.org/W2093295511","https://openalex.org/W2093883082","https://openalex.org/W2095939746","https://openalex.org/W2099025616","https://openalex.org/W2100849967","https://openalex.org/W2100999894","https://openalex.org/W2101222632","https://openalex.org/W2102275974","https://openalex.org/W2102278945","https://openalex.org/W2102816274","https://openalex.org/W2103255565","https://openalex.org/W2104466885","https://openalex.org/W2104683498","https://openalex.org/W2105133112","https://openalex.org/W2105545925","https://openalex.org/W2106774938","https://openalex.org/W2107314112","https://openalex.org/W2107337799","https://openalex.org/W2107366172","https://openalex.org/W2107627035","https://openalex.org/W2109000783","https://openalex.org/W2113880071","https://openalex.org/W2116122104","https://openalex.org/W2117583440","https://openalex.org/W2119404103","https://openalex.org/W2119452439","https://openalex.org/W2123921804","https://openalex.org/W2124511335","https://openalex.org/W2127524244","https://openalex.org/W2128701472","https://openalex.org/W2128874237","https://openalex.org/W2130819115","https://openalex.org/W2133377110","https://openalex.org/W2134256488","https://openalex.org/W2134487562","https://openalex.org/W2137455182","https://openalex.org/W2140729960","https://openalex.org/W2141116637","https://openalex.org/W2142206193","https://openalex.org/W2144792857","https://openalex.org/W2146358743","https://openalex.org/W2146547152","https://openalex.org/W2147524392","https://openalex.org/W2148620949","https://openalex.org/W2149335334","https://openalex.org/W2149736989","https://openalex.org/W2150413484","https://openalex.org/W2150936392","https://openalex.org/W2154382308","https://openalex.org/W2155336429","https://openalex.org/W2155345038","https://openalex.org/W2155772493","https://openalex.org/W2156447791","https://openalex.org/W2158541299","https://openalex.org/W2162648640","https://openalex.org/W2163149892","https://openalex.org/W2163360164","https://openalex.org/W2163813691","https://openalex.org/W2166453609","https://openalex.org/W2170818414","https://openalex.org/W2179438025","https://openalex.org/W2192908784","https://openalex.org/W2223486414","https://openalex.org/W2264862529","https://openalex.org/W2293968912","https://openalex.org/W2341539131","https://openalex.org/W2346071487","https://openalex.org/W2368051645","https://openalex.org/W2409013835","https://openalex.org/W2410434240","https://openalex.org/W2415322025","https://openalex.org/W2416119739","https://openalex.org/W2416744721","https://openalex.org/W2509465044","https://openalex.org/W2525507785","https://openalex.org/W2555364622","https://openalex.org/W2560140650","https://openalex.org/W2566469243","https://openalex.org/W2592817720","https://openalex.org/W2595516268","https://openalex.org/W2600121124","https://openalex.org/W2617540636","https://openalex.org/W2742485839","https://openalex.org/W2743136711","https://openalex.org/W2746657656","https://openalex.org/W2760482166","https://openalex.org/W2762101500","https://openalex.org/W2762606405","https://openalex.org/W2773308724","https://openalex.org/W2782752865","https://openalex.org/W2804344327","https://openalex.org/W2805349308","https://openalex.org/W2807420818","https://openalex.org/W2884361791","https://openalex.org/W2889348647","https://openalex.org/W2899944923","https://openalex.org/W2901429835","https://openalex.org/W2914390180","https://openalex.org/W2916518978","https://openalex.org/W2942754498","https://openalex.org/W2951822269","https://openalex.org/W4212766227"],"related_works":["https://openalex.org/W7139216624","https://openalex.org/W7134412309","https://openalex.org/W1980593396","https://openalex.org/W7151630453","https://openalex.org/W198964758","https://openalex.org/W7148851113","https://openalex.org/W3082743537","https://openalex.org/W2470556107","https://openalex.org/W7214263730","https://openalex.org/W7204014634"],"abstract_inverted_index":{"R\u00e9gulation":[0],"\u00e9pig\u00e9n\u00e9tique":[1],"de":[2,8,33,39,47,61,92,102,122,136,190,200,210,222,238,245,248,250,269,290,292,295,298],"la":[3,22,31,45,89,123,211,223,227,266],"transcription":[4,90,267],"des":[5,12,37,68,109,151,193,208,257,274],"g\u00e8nes":[6,41,62,94,252,258,271,293],"contenant":[7,294],"l\u2019h\u00e9t\u00e9rochromatine":[9,34,65,296],"La":[10,178],"maturation":[11],"ARN":[13],"implique":[14],"un":[15,205],"grand":[16],"nombre":[17],"d\u2019\u00e9v\u00e8nements":[18],"post-transcriptionnels,":[19],"parmi":[20,255],"lesquels":[21],"polyad\u00e9nylation":[23,46,118,249,291],"qui":[24,263],"constitue":[25],"une":[26,56,117,188,235],"\u00e9tape":[27],"cl\u00e9.":[28],"Chez":[29],"Arabidopsis,":[30],"pr\u00e9sence":[32],"au":[35,66,120],"niveau":[36,67,121,198],"introns":[38,69],"certains":[40],"peut":[42],"influencer":[43],"consid\u00e9rablement":[44],"leur":[48],"transcrits.":[49],"INCREASED":[50],"IN":[51],"BONSAI":[52],"METHYLATION2":[53],"(IBM2)":[54],"est":[55,234],"prot\u00e9inequi":[57],"contr\u00f4le":[58],"cette":[59,137,184],"cat\u00e9gorie":[60],"en":[63,96,106,140,220,302],"reconnaissant":[64],"via":[70],"son":[71,82],"domaine":[72],"BOMO-ADJACENT":[73],"HOMOLOGY":[74],"(BAH).":[75],"IBM2":[76,174,278],"se":[77],"lie":[78],"\u00e0":[79,116,130,183,187,240],"l\u2019ARNm":[80],"par":[81,260],"motif":[83],"RNA":[84],"RECOGNOTION":[85],"(RRM),":[86],"afin":[87],"d\u2019assurer":[88],"compl\u00e8te":[91,268],"ces":[93,270],"cibles":[95,194],"favorisant":[97],"l\u2019utilisation":[98,244],"d\u2019un":[99,197],"site":[100,289],"distal":[101],"polyad\u00e9nylation.":[103],"Par":[104],"cons\u00e9quent,":[105],"mutant":[107],"IBM2,":[108,225,261],"plus":[110],"transcrits":[111,201],"courts":[112],"sont":[113],"synth\u00e9tis\u00e9s":[114],"suite":[115],"pr\u00e9coce":[119],"r\u00e9gionh\u00e9t\u00e9rochromatique.":[124],"Durant":[125],"ma":[126],"th\u00e8se,":[127],"j\u2019ai":[128],"cherch\u00e9":[129],"comprendre":[131],"les":[132],"m\u00e9canismes":[133],"mol\u00e9culaires":[134],"sous-jacents":[135],"r\u00e9gulation":[138],"tout":[139],"\u00e9tudiant":[141],"le":[142,286],"r\u00f4le":[143],"du":[144,180,288],"complexe":[145],"prot\u00e9ique":[146],"IBM2.":[147],"Nous":[148],"avons":[149,215],"identifi\u00e9":[150,216],"prot\u00e9ines":[152,300],"partenaires":[153],"d\u2019IBM2":[154],"d\u00e9j\u00e0":[155],"\u00e9tudi\u00e9es":[156],"telle":[157],"que":[158,265,285,306],"ENHANCED":[159],"DOWNY":[160],"MILDEW2":[161],"(EDM2)":[162],"et":[163,175,279],"ASI-IMMUNOPRECIPITATED":[164],"PROTEIN1":[165],"(AIPP1),":[166],"ainsi":[167,305],"qu\u2019une":[168],"nouvelle":[169],"prot\u00e9ine":[170,185,228,236],"interagissant":[171],"physiquement":[172],"avec":[173,254,308],"d\u2019autres":[176,309],"prot\u00e9ines.":[177],"mutation":[179,212],"g\u00e8ne":[181],"correspondant":[182],"conduit":[186],"r\u00e9duction":[189],"l\u2019expression":[191],"globale":[192],"d\u2019IBM2test\u00e9es,":[195],"accompagn\u00e9e":[196],"r\u00e9duit":[199],"longs":[202],"fonctionnels.":[203],"Moyennant":[204],"crible":[206],"g\u00e9n\u00e9tique":[207],"suppresseurs":[209],"ibm2,":[213],"nous":[214],"plusieurs":[217,251,299],"facteurs":[218],"agissant":[219,301],"amont":[221],"voie":[224],"notamment":[226],"FLOWERING":[229],"TIME":[230],"CONTROL":[231],"(FPA).":[232],"FPA":[233],"capable":[237],"s\u2019associer":[239],"l\u2019ARN":[241],"pour":[242],"favoriser":[243],"sites":[246],"proximaux":[247],"cibles,":[253],"eux":[256],"contr\u00f4l\u00e9s":[259],"ce":[262],"sugg\u00e8re":[264],"d\u00e9pend":[272,297],"\u00e9troitement":[273],"actions":[275],"antagonistes":[276],"entre":[277],"FPA.":[280],"Nos":[281],"r\u00e9sultats":[282],"ont":[283],"montr\u00e9":[284],"choix":[287],"diff\u00e9rents":[303],"complexes":[304],"l\u2019interconnexion":[307],"voies.":[310]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-04-04T00:00:00"}
