{"id":"https://openalex.org/W7148524872","doi":"https://doi.org/10.1016/j.vaccine.2026.128544","title":"Effectiveness of JN.1-adapted COVID-19 vaccine against medically attended SARS-CoV-2 infection and COVID-19 hospitalization in adults in Japan, from October 2024 to April 2025: VERSUS","display_name":"Effectiveness of JN.1-adapted COVID-19 vaccine against medically attended SARS-CoV-2 infection and COVID-19 hospitalization in adults in Japan, from October 2024 to April 2025: VERSUS","publication_year":2026,"publication_date":"2026-04-01","ids":{"openalex":"https://openalex.org/W7148524872","doi":"https://doi.org/10.1016/j.vaccine.2026.128544","pmid":"https://pubmed.ncbi.nlm.nih.gov/41932291"},"language":"en","primary_location":{"id":"doi:10.1016/j.vaccine.2026.128544","doi":"https://doi.org/10.1016/j.vaccine.2026.128544","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2026.128544","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.vaccine.2026.128544","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5124134773","display_name":"Haruka Maeda","orcid":"https://orcid.org/0000-0002-0014-2602","observed_orcids":["https://orcid.org/0000-0002-0014-2602"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]},{"id":"https://openalex.org/I4405287243","display_name":"Institute of Tropical Medicine, Nagasaki University","ror":"https://ror.org/04hv4pw79","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Haruka Maeda","raw_affiliation_strings":["Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan. Electronic address: mharuka@nagasaki-u.ac.jp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan. Electronic address: mharuka@nagasaki-u.ac.jp","institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021843258","display_name":"Nobuo Saito","orcid":"https://orcid.org/0000-0002-4396-5000","observed_orcids":["https://orcid.org/0000-0002-4396-5000"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]},{"id":"https://openalex.org/I4405287243","display_name":"Institute of Tropical Medicine, Nagasaki University","ror":"https://ror.org/04hv4pw79","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuo Saito","raw_affiliation_strings":["Kenya Research Station, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kenya Research Station, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan","institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120726343","display_name":"Ataru Igarashi","orcid":"https://orcid.org/0000-0001-6307-6916","observed_orcids":["https://orcid.org/0000-0001-6307-6916"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ataru Igarashi","raw_affiliation_strings":["Department of Health Policy and Public Health, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Policy and Public Health, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101010130","display_name":"Masayuki Ishida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103966","display_name":"Chikamori Hospital","ror":"https://ror.org/01fzw3g31","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103966"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masayuki Ishida","raw_affiliation_strings":["Department of Infectious Disease Medicine, Chikamori Hospital, Kochi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Disease Medicine, Chikamori Hospital, Kochi, Japan","institution_ids":["https://openalex.org/I4210103966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110415164","display_name":"Mayumi Terada","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mayumi Terada","raw_affiliation_strings":["Department of Internal Medicine, Nijigaoka Hospital, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Nijigaoka Hospital, Nagasaki, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042800717","display_name":"Ryosuke Osawa","orcid":"https://orcid.org/0000-0002-8480-9805","observed_orcids":["https://orcid.org/0000-0002-8480-9805"]},"institutions":[{"id":"https://openalex.org/I4210114023","display_name":"Kameda Medical Center","ror":"https://ror.org/01gf00k84","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210114023"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryosuke Osawa","raw_affiliation_strings":["Department of Infectious Diseases, Kameda Medical Center, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Kameda Medical Center, Chiba, Japan","institution_ids":["https://openalex.org/I4210114023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082153773","display_name":"Naoto Hosokawa","orcid":"https://orcid.org/0009-0005-2858-1593","observed_orcids":["https://orcid.org/0009-0005-2858-1593"]},"institutions":[{"id":"https://openalex.org/I4210114023","display_name":"Kameda Medical Center","ror":"https://ror.org/01gf00k84","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210114023"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Hosokawa","raw_affiliation_strings":["Department of Infectious Diseases, Kameda Medical Center, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Kameda Medical Center, Chiba, Japan","institution_ids":["https://openalex.org/I4210114023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018870434","display_name":"Kei Nakashima","orcid":"https://orcid.org/0000-0001-6080-1801","observed_orcids":["https://orcid.org/0000-0001-6080-1801"]},"institutions":[{"id":"https://openalex.org/I4210114023","display_name":"Kameda Medical Center","ror":"https://ror.org/01gf00k84","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210114023"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kei Nakashima","raw_affiliation_strings":["Department of Pulmonology, Kameda Medical Center, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonology, Kameda Medical Center, Chiba, Japan","institution_ids":["https://openalex.org/I4210114023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032012310","display_name":"Iori Motohashi","orcid":"https://orcid.org/0000-0002-9518-7909","observed_orcids":["https://orcid.org/0000-0002-9518-7909"]},"institutions":[{"id":"https://openalex.org/I4405283616","display_name":"Kawasaki Municipal Tama Hospital","ror":"https://ror.org/01zsn5506","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405283616"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Iori Motohashi","raw_affiliation_strings":["Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Kanagawa, Japan","institution_ids":["https://openalex.org/I4405283616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003893295","display_name":"Hiroshi Kamura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroshi Kamura","raw_affiliation_strings":["Loco Clinic Nakameguro, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Loco Clinic Nakameguro, Tokyo, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025598555","display_name":"Tomoichiro Hayakawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tomoichiro Hayakawa","raw_affiliation_strings":["Hayakawa Internal Medicine Clinic, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hayakawa Internal Medicine Clinic, Fukuoka, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075927994","display_name":"Osamu Teshigahara","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Osamu Teshigahara","raw_affiliation_strings":["Mizuho Street Clinic, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mizuho Street Clinic, Aichi, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047956159","display_name":"Sadaharu Asami","orcid":"https://orcid.org/0000-0001-8346-8992","observed_orcids":["https://orcid.org/0000-0001-8346-8992"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sadaharu Asami","raw_affiliation_strings":["Department of Cardiology, Musashino Tokushukai Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Musashino Tokushukai Hospital, Tokyo, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110335987","display_name":"Satoshi Kudo","orcid":"https://orcid.org/0009-0003-1375-9366","observed_orcids":["https://orcid.org/0009-0003-1375-9366"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satoshi Kudo","raw_affiliation_strings":["Department of Nursing, Musashino Tokushukai Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nursing, Musashino Tokushukai Hospital, Tokyo, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043849320","display_name":"Takashi Matono","orcid":"https://orcid.org/0000-0001-9957-0510","observed_orcids":["https://orcid.org/0000-0001-9957-0510"]},"institutions":[{"id":"https://openalex.org/I177136067","display_name":"Saga University","ror":"https://ror.org/04f4wg107","country_code":"JP","type":"education","lineage":["https://openalex.org/I177136067"]},{"id":"https://openalex.org/I4210144416","display_name":"Aso Iizuka Hospital","ror":"https://ror.org/04tg98e93","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210144416"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Matono","raw_affiliation_strings":["Department of Infectious Diseases, Aso Iizuka Hospital, Fukuoka, Japan; Division of Infectious Disease and Hospital Epidemiology, Saga University Hospital, Saga, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Aso Iizuka Hospital, Fukuoka, Japan; Division of Infectious Disease and Hospital Epidemiology, Saga University Hospital, Saga, Japan","institution_ids":["https://openalex.org/I177136067","https://openalex.org/I4210144416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016079420","display_name":"Rentaro Oda","orcid":"https://orcid.org/0000-0002-6066-2853","observed_orcids":["https://orcid.org/0000-0002-6066-2853"]},"institutions":[{"id":"https://openalex.org/I4210151172","display_name":"Tokyo Metropolitan Tama Medical Center","ror":"https://ror.org/04c3ebg91","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210151172"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Rentaro Oda","raw_affiliation_strings":["Department of Infectious Diseases, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Diseases, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, Japan","institution_ids":["https://openalex.org/I4210151172"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063125042","display_name":"Yasuji Ohara","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yasuji Ohara","raw_affiliation_strings":["Jin Sakura Clinic, Aichi, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jin Sakura Clinic, Aichi, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060321099","display_name":"Toru Morikawa","orcid":"https://orcid.org/0000-0001-8014-5282","observed_orcids":["https://orcid.org/0000-0001-8014-5282"]},"institutions":[{"id":"https://openalex.org/I4210113106","display_name":"Nara City Hospital","ror":"https://ror.org/01dzpsy49","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210113106"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Morikawa","raw_affiliation_strings":["Department of General Medicine, Nara City Hospital, Nara, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Medicine, Nara City Hospital, Nara, Japan","institution_ids":["https://openalex.org/I4210113106"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157843924","display_name":"Yukihiro Sugimoto","orcid":"https://orcid.org/0009-0004-1233-2894","observed_orcids":["https://orcid.org/0009-0004-1233-2894"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yukihiro Sugimoto","raw_affiliation_strings":["Department of Respiratory Medicine, Fukuoka Seishukai Hospital, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Fukuoka Seishukai Hospital, Fukuoka, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087956208","display_name":"Haruki Imura","orcid":"https://orcid.org/0000-0001-8613-2431","observed_orcids":["https://orcid.org/0000-0001-8613-2431"]},"institutions":[{"id":"https://openalex.org/I4210097197","display_name":"Rakuwakai Otowa Hospital","ror":"https://ror.org/012nfex57","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210097197"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Haruki Imura","raw_affiliation_strings":["Department of Infectious Disease Medicine, Rakuwakai Otowa Hospital, Kyoto, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infectious Disease Medicine, Rakuwakai Otowa Hospital, Kyoto, Japan","institution_ids":["https://openalex.org/I4210097197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036104845","display_name":"Eiichiro Sando","orcid":"https://orcid.org/0000-0001-7824-5313","observed_orcids":["https://orcid.org/0000-0001-7824-5313"]},"institutions":[{"id":"https://openalex.org/I130830085","display_name":"Fukushima Medical University","ror":"https://ror.org/012eh0r35","country_code":"JP","type":"education","lineage":["https://openalex.org/I130830085"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eiichiro Sando","raw_affiliation_strings":["Department of Infection Control, Fukushima Medical University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection Control, Fukushima Medical University, Japan","institution_ids":["https://openalex.org/I130830085"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027589848","display_name":"Osamu Kuwamitsu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Osamu Kuwamitsu","raw_affiliation_strings":["Gohongi Clinic, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gohongi Clinic, Tokyo, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002290123","display_name":"Tomoo Kishaba","orcid":"https://orcid.org/0000-0003-3335-5409","observed_orcids":["https://orcid.org/0000-0003-3335-5409"]},"institutions":[{"id":"https://openalex.org/I4210121081","display_name":"Okinawa Prefectural Chubu Hospital","ror":"https://ror.org/03mpa4w20","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210121081"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomoo Kishaba","raw_affiliation_strings":["Department of Respiratory Medicine, Okinawa Chubu Hospital, Okinawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Okinawa Chubu Hospital, Okinawa, Japan","institution_ids":["https://openalex.org/I4210121081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031906373","display_name":"Azusa Fujisawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Azusa Fujisawa","raw_affiliation_strings":["Department of Health Policy and Public Health, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Policy and Public Health, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132773907","display_name":"Sayaka Ohno","orcid":"https://orcid.org/0009-0000-5878-8994","observed_orcids":["https://orcid.org/0009-0000-5878-8994"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sayaka Ohno","raw_affiliation_strings":["Department of Health Policy and Public Health, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Policy and Public Health, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043259928","display_name":"Shingo Masuda","orcid":"https://orcid.org/0009-0002-3902-4635","observed_orcids":["https://orcid.org/0009-0002-3902-4635"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]},{"id":"https://openalex.org/I4405287243","display_name":"Institute of Tropical Medicine, Nagasaki University","ror":"https://ror.org/04hv4pw79","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shingo Masuda","raw_affiliation_strings":["Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan","institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032625744","display_name":"Motoi Suzuki","orcid":"https://orcid.org/0000-0002-8340-0880","observed_orcids":["https://orcid.org/0000-0002-8340-0880"]},"institutions":[{"id":"https://openalex.org/I4210086300","display_name":"National Institute of Infectious Diseases","ror":"https://ror.org/001ggbx22","country_code":"JP","type":"government","lineage":["https://openalex.org/I1333985979","https://openalex.org/I4210086300","https://openalex.org/I4405286871"]},{"id":"https://openalex.org/I4405286871","display_name":"Japan Institute for Health Security","ror":"https://ror.org/03c8bq125","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1333985979","https://openalex.org/I4405286871"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motoi Suzuki","raw_affiliation_strings":["Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan","institution_ids":["https://openalex.org/I4210086300","https://openalex.org/I4405286871"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5124369592","display_name":"Konosuke Morimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]},{"id":"https://openalex.org/I4405287243","display_name":"Institute of Tropical Medicine, Nagasaki University","ror":"https://ror.org/04hv4pw79","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Konosuke Morimoto","raw_affiliation_strings":["Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Infections, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan","institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405287243"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5124134773"],"corresponding_institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405287243"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":{"value":3620,"currency":"USD","value_usd":3620},"fwci":7.2475,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.94672936,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"80","issue":null,"first_page":"128544","last_page":"128544"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19-vaccine-effectiveness","display_name":"COVID-19 vaccine effectiveness","score":0.9340000152587891},{"id":"https://openalex.org/keywords/covid-19-hospitalization","display_name":"COVID-19 hospitalization","score":0.8529999852180481},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.5189999938011169},{"id":"https://openalex.org/keywords/respiratory-failure","display_name":"respiratory failure","score":0.671999990940094},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.3319999873638153},{"id":"https://openalex.org/keywords/japan","display_name":"Japan","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8853999972343445},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4113999903202057},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.35280001163482666},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3515999913215637},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.3458000123500824},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.2621999979019165},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.26109999418258667},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2522999942302704},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.23190000653266907},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.22849999368190765}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000087507","descriptor_name":"Vaccine Efficacy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006760","descriptor_name":"Hospitalization","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014611","descriptor_name":"Vaccination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.vaccine.2026.128544","doi":"https://doi.org/10.1016/j.vaccine.2026.128544","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2026.128544","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},{"id":"pmid:41932291","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41932291","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:01160:0007415992","doi":null,"is_oa":true,"landing_page_url":"https://nagasaki-u.repo.nii.ac.jp/records/2004133","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Vaccine","raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1016/j.vaccine.2026.128544","doi":"https://doi.org/10.1016/j.vaccine.2026.128544","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2026.128544","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G5206120136","display_name":"\u30ef\u30af\u30c1\u30f3\u306e\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u3092\u8a55\u4fa1\u3059\u308b\u4f53\u5236\u306e\u69cb\u7bc9\u306b\u95a2\u3059\u308b\u5b9f\u8a3c\u7684\u7814\u7a76","funder_award_id":"24HA2016","funder_id":"https://openalex.org/F4320321945","funder_display_name":"Ministry of Health, Labour and Welfare"}],"funders":[{"id":"https://openalex.org/F4320315544","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94"},{"id":"https://openalex.org/F4320321945","display_name":"Ministry of Health, Labour and Welfare","ror":"https://ror.org/03mwa7s65"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W2006834697","https://openalex.org/W2093274439","https://openalex.org/W3176552995","https://openalex.org/W4220727497","https://openalex.org/W4225821402","https://openalex.org/W4323532518","https://openalex.org/W4376631082","https://openalex.org/W4388947547","https://openalex.org/W4390548048","https://openalex.org/W4391361626","https://openalex.org/W4400066840","https://openalex.org/W4404091918","https://openalex.org/W4404126431","https://openalex.org/W4404558857","https://openalex.org/W4408020406","https://openalex.org/W4408648893","https://openalex.org/W4412868872","https://openalex.org/W4414382605","https://openalex.org/W4415478571"],"related_works":["https://openalex.org/W7171260798","https://openalex.org/W4413949185","https://openalex.org/W7127439443","https://openalex.org/W4414382605","https://openalex.org/W7202283909","https://openalex.org/W4416667438","https://openalex.org/W4281750990","https://openalex.org/W4406924212","https://openalex.org/W4412743857","https://openalex.org/W6981375933"],"abstract_inverted_index":{"BACKGROUND:":[0],"Evaluating":[1],"COVID-19":[2,23,34,121,190],"vaccine":[3,10,24,102,135],"effectiveness":[4,20],"(VE)":[5],"is":[6],"essential":[7],"to":[8,280],"guide":[9],"policy":[11],"as":[12],"SARS-CoV-2":[13,31],"continues":[14],"evolving.":[15],"This":[16],"study":[17,47],"evaluated":[18],"the":[19,233,282],"of":[21,65,86,100,119,133,265,275],"JN.1-adapted":[22],"(JN.1":[25],"vaccine)":[26],"against":[27,136,189,207,217,226,241,253],"medically":[28],"attended":[29],"symptomatic":[30,72,137],"infection":[32,73,138],"and":[33,75,156,176,236,256,267],"hospitalization":[35,97,191,218,227,242],"among":[36,259],"adults":[37,76,173,193,260],"in":[38,48,71,96,172,181,192,261],"Japan.":[39],"METHODS:":[40],"We":[41],"conducted":[42],"a":[43],"multicenter":[44],"test-negative":[45],"case-control":[46],"Japan,":[49],"from":[50],"October":[51],"1,":[52],"2024-April":[53],"30,":[54],"2025.":[55],"Adults":[56],"aged":[57,77,174,183,194],"\u226518":[58],"years":[59,79],"with":[60,81,110,219,228,243],"\u22651":[61],"sign":[62],"or":[63,84],"symptom":[64],"acute":[66,87],"respiratory":[67,88,220],"illness":[68,89],"were":[69,94],"included":[70,95],"analysis,":[74],"\u226560":[78,195],"hospitalized":[80],"\u22652":[82],"signs":[83],"symptoms":[85],"and/or":[90],"radiographically":[91,244],"confirmed":[92,245],"pneumonia":[93],"analysis.":[98],"VE":[99,132,166,188,206],"JN.1":[101,116,134,248],"was":[103,139,167,196,211],"estimated":[104],"by":[105,232],"comparing":[106],"those":[107,111,182],"who":[108,112],"received":[109],"did":[113],"not":[114],"receive":[115],"vaccine,":[117],"regardless":[118],"prior":[120],"vaccination,":[122],"using":[123],"mixed-effects":[124],"logistic":[125],"regression":[126],"models.":[127],"RESULTS:":[128],"Among":[129,185],"5413":[130],"episodes,":[131],"55.1%":[140],"(95%":[141,150,158,169,178,198,214,223,238],"confidence":[142],"interval":[143],"[CI]:":[144],"35.0-69.0)":[145],"at":[146,153,161,201],"\u22657":[147,202],"days,":[148,155],"52.7%":[149],"CI:":[151,159,170,179,215,224,239],"22.4-71.2)":[152],"7-60":[154],"57.6%":[157],"28.2-75.0)":[160],">60":[162],"days":[163,203],"after":[164,204],"vaccination.":[165,205],"61.0%":[168],"30.2-78.2)":[171],"18-64":[175],"44.3%":[177],"8.4-66.1)":[180],"\u226565.":[184],"1106":[186],"hospitalizations,":[187],"61.8%":[197],"CI,":[199],"21.5-81.4)":[200],"more":[208],"severe":[209,257],"disease":[210,283],"similar:":[212],"60.1%":[213],"4.0-83.4)":[216],"failure,":[221],"55.7%":[222],"8.3-78.6)":[225],"moderate-to-severe":[229],"diseases":[230],"defined":[231],"CURB-65":[234],"score,":[235],"66.4%":[237],"19.9-86.0)":[240],"pneumonia.":[246],"CONCLUSION:":[247],"vaccines":[249],"provided":[250],"additional":[251],"protection":[252],"both":[254],"mild":[255],"outcomes":[258],"Japan":[262],"during":[263],"circulation":[264],"KP.3":[266],"XEC":[268],"variants.":[269],"These":[270],"findings":[271],"support":[272],"continued":[273],"vaccination":[274],"adults,":[276,279],"particularly":[277],"older":[278],"mitigate":[281],"burden.":[284]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2026-04-03T00:00:00"}