{"id":"https://openalex.org/W7148425508","doi":"https://doi.org/10.2196/87628","title":"mHealth-Supported Exercise Rehabilitation to Reverse Frailty After Autologous Transplantation in Multiple Myeloma: Randomized Controlled Trial","display_name":"mHealth-Supported Exercise Rehabilitation to Reverse Frailty After Autologous Transplantation in Multiple Myeloma: Randomized Controlled Trial","publication_year":2026,"publication_date":"2026-04-03","ids":{"openalex":"https://openalex.org/W7148425508","doi":"https://doi.org/10.2196/87628","pmid":"https://pubmed.ncbi.nlm.nih.gov/42166768","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13237530"},"language":"en","primary_location":{"id":"doi:10.2196/87628","doi":"https://doi.org/10.2196/87628","is_oa":true,"landing_page_url":"https://doi.org/10.2196/87628","pdf_url":null,"source":{"id":"https://openalex.org/S2764493120","display_name":"JMIR mhealth and uhealth","issn_l":"2291-5222","issn":["2291-5222"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.2196/87628","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102845801","display_name":"Kyuwan Lee","orcid":"https://orcid.org/0000-0002-2015-4109","observed_orcids":["https://orcid.org/0000-0002-2015-4109"]},"institutions":[{"id":"https://openalex.org/I138925566","display_name":"Ewha Womans University","ror":"https://ror.org/053fp5c05","country_code":"KR","type":"education","lineage":["https://openalex.org/I138925566"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Kyuwan Lee","raw_affiliation_strings":["Kinesiology & Sports Studies, Ewha Womans University, Seoul, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-2015-4109","affiliations":[{"raw_affiliation_string":"Kinesiology & Sports Studies, Ewha Womans University, Seoul, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I138925566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011296099","display_name":"Justin Shamunee","orcid":"https://orcid.org/0009-0004-1345-0200","observed_orcids":["https://orcid.org/0009-0004-1345-0200"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I4210141674","display_name":"Cedars-Sinai Smidt Heart Institute","ror":"https://ror.org/041vn2102","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210141674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justin Shamunee","raw_affiliation_strings":["Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States"],"raw_orcid":"https://orcid.org/0009-0004-1345-0200","affiliations":[{"raw_affiliation_string":"Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I1282927834","https://openalex.org/I4210141674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038196799","display_name":"Haehyun Lee","orcid":"https://orcid.org/0000-0003-4820-6924","observed_orcids":["https://orcid.org/0000-0003-4820-6924","https://orcid.org/0000-0002-6205-1984"]},"institutions":[{"id":"https://openalex.org/I133999245","display_name":"University of Nevada, Las Vegas","ror":"https://ror.org/0406gha72","country_code":"US","type":"education","lineage":["https://openalex.org/I133999245"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haehyun Lee","raw_affiliation_strings":["University of Nevada, Las Vegas, Las Vegas, NV, United States"],"raw_orcid":"https://orcid.org/0000-0002-6205-1984","affiliations":[{"raw_affiliation_string":"University of Nevada, Las Vegas, Las Vegas, NV, United States","institution_ids":["https://openalex.org/I133999245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103055497","display_name":"Xinyi Du","orcid":"https://orcid.org/0000-0003-4949-3689","observed_orcids":["https://orcid.org/0000-0003-4949-3689","https://orcid.org/0009-0008-5444-9635"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4210110459","display_name":"City of Hope","ror":"https://ror.org/01z1vct10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinyi Du","raw_affiliation_strings":["Population Sciences, City of Hope, Duarte, CA, United States"],"raw_orcid":"https://orcid.org/0009-0008-5444-9635","affiliations":[{"raw_affiliation_string":"Population Sciences, City of Hope, Duarte, CA, United States","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015815936","display_name":"Lanie Lindenfeld","orcid":"https://orcid.org/0000-0003-1135-2995","observed_orcids":["https://orcid.org/0000-0003-1135-2995"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4210110459","display_name":"City of Hope","ror":"https://ror.org/01z1vct10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lanie Lindenfeld","raw_affiliation_strings":["Population Sciences, City of Hope, Duarte, CA, United States"],"raw_orcid":"https://orcid.org/0000-0003-1135-2995","affiliations":[{"raw_affiliation_string":"Population Sciences, City of Hope, Duarte, CA, United States","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112839769","display_name":"Amrita Y. Krishnan","orcid":"https://orcid.org/0000-0002-8484-175X","observed_orcids":["https://orcid.org/0000-0002-8484-175X"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4210110459","display_name":"City of Hope","ror":"https://ror.org/01z1vct10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amrita Krishnan","raw_affiliation_strings":["Population Sciences, City of Hope, Duarte, CA, United States"],"raw_orcid":"https://orcid.org/0000-0002-8484-175X","affiliations":[{"raw_affiliation_string":"Population Sciences, City of Hope, Duarte, CA, United States","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040738036","display_name":"Nitya Nathwani","orcid":"https://orcid.org/0000-0003-4329-8102","observed_orcids":["https://orcid.org/0000-0003-4329-8102"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4210110459","display_name":"City of Hope","ror":"https://ror.org/01z1vct10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nitya Nathwani","raw_affiliation_strings":["Population Sciences, City of Hope, Duarte, CA, United States"],"raw_orcid":"https://orcid.org/0000-0003-4329-8102","affiliations":[{"raw_affiliation_string":"Population Sciences, City of Hope, Duarte, CA, United States","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010408701","display_name":"Florence Lennie Wong","orcid":"https://orcid.org/0000-0002-4333-5017","observed_orcids":["https://orcid.org/0000-0002-4333-5017"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4210110459","display_name":"City of Hope","ror":"https://ror.org/01z1vct10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F Lennie Wong","raw_affiliation_strings":["Population Sciences, City of Hope, Duarte, CA, United States"],"raw_orcid":"https://orcid.org/0000-0002-4333-5017","affiliations":[{"raw_affiliation_string":"Population Sciences, City of Hope, Duarte, CA, United States","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042736213","display_name":"Saro H. Armenian","orcid":"https://orcid.org/0000-0003-2604-8603","observed_orcids":["https://orcid.org/0000-0003-2604-8603"]},"institutions":[{"id":"https://openalex.org/I1301076528","display_name":"City Of Hope National Medical Center","ror":"https://ror.org/00w6g5w60","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528"]},{"id":"https://openalex.org/I4210110459","display_name":"City of Hope","ror":"https://ror.org/01z1vct10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saro Armenian","raw_affiliation_strings":["Population Sciences, City of Hope, Duarte, CA, United States"],"raw_orcid":"https://orcid.org/0000-0003-2604-8603","affiliations":[{"raw_affiliation_string":"Population Sciences, City of Hope, Duarte, CA, United States","institution_ids":["https://openalex.org/I1301076528","https://openalex.org/I4210110459"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5102845801"],"corresponding_institution_ids":["https://openalex.org/I138925566"],"apc_list":{"value":2850,"currency":"USD","value_usd":2850},"apc_paid":{"value":2850,"currency":"USD","value_usd":2850},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.17981521,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":"e87628","last_page":"e87628"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.4196999967098236,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.4196999967098236,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.29660001397132874,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.16760000586509705,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.902999997138977},{"id":"https://openalex.org/keywords/frailty","display_name":"frailty","score":0.9380000233650208},{"id":"https://openalex.org/keywords/autologous-stem-cell-transplantation","display_name":"autologous stem cell transplantation","score":0.9660000205039978},{"id":"https://openalex.org/keywords/mobile-health","display_name":"mobile health","score":0.7300000190734863},{"id":"https://openalex.org/keywords/exercise-rehabilitation","display_name":"exercise rehabilitation","score":0.8019999861717224},{"id":"https://openalex.org/keywords/tele-exercise","display_name":"tele-exercise","score":0.9150000214576721},{"id":"https://openalex.org/keywords/home-based-exercise","display_name":"home-based exercise","score":0.9620000123977661},{"id":"https://openalex.org/keywords/physical-functioning","display_name":"physical function","score":0.7459999918937683},{"id":"https://openalex.org/keywords/frailty-phenotype","display_name":"Fried frailty phenotype","score":0.847000002861023},{"id":"https://openalex.org/keywords/short-physical-performance-battery","display_name":"Short Physical Performance Battery","score":0.8309999704360962},{"id":"https://openalex.org/keywords/walking-speed","display_name":"walking speed","score":0.7419999837875366},{"id":"https://openalex.org/keywords/handgrip-strength","display_name":"grip strength","score":0.9750000238418579},{"id":"https://openalex.org/keywords/exercise-adherence","display_name":"exercise adherence","score":0.6019999980926514},{"id":"https://openalex.org/keywords/remote-monitoring","display_name":"remote monitoring","score":0.34700000286102295},{"id":"https://openalex.org/keywords/cancer-survivors","display_name":"cancer survivors","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7892000079154968},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7847999930381775},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.6406000256538391},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6096000075340271},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.4075999855995178},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.3921000063419342},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.3700999915599823},{"id":"https://openalex.org/C2777771302","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Exercise therapy","level":3,"score":0.3100000023841858},{"id":"https://openalex.org/C204243189","wikidata":"https://www.wikidata.org/wiki/Q1363085","display_name":"Randomization","level":3,"score":0.29660001397132874},{"id":"https://openalex.org/C181588539","wikidata":"https://www.wikidata.org/wiki/Q219067","display_name":"Physical exercise","level":2,"score":0.2939999997615814},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.29010000824928284},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2870999872684479},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.28029999136924744},{"id":"https://openalex.org/C79544238","wikidata":"https://www.wikidata.org/wiki/Q423243","display_name":"Activities of daily living","level":2,"score":0.27320000529289246}],"mesh":[{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":true},{"descriptor_ui":"D000073496","descriptor_name":"Frailty","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005081","descriptor_name":"Exercise Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005081","descriptor_name":"Exercise Therapy","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D005081","descriptor_name":"Exercise Therapy","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":false},{"descriptor_ui":"D017216","descriptor_name":"Telemedicine","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":false},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018380","descriptor_name":"Hematopoietic Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.2196/87628","doi":"https://doi.org/10.2196/87628","is_oa":true,"landing_page_url":"https://doi.org/10.2196/87628","pdf_url":null,"source":{"id":"https://openalex.org/S2764493120","display_name":"JMIR mhealth and uhealth","issn_l":"2291-5222","issn":["2291-5222"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"journal-article"},{"id":"doi:10.2196/preprints.87628","doi":"https://doi.org/10.2196/preprints.87628","is_oa":true,"landing_page_url":"https://doi.org/10.2196/preprints.87628","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmid:42166768","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42166768","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13237530","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42166768/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR Mhealth Uhealth","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:e8eb95f033e34e4b975ca3cdede3469d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e8eb95f033e34e4b975ca3cdede3469d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JMIR mHealth and uHealth, Vol 14, p e87628 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2196/87628","doi":"https://doi.org/10.2196/87628","is_oa":true,"landing_page_url":"https://doi.org/10.2196/87628","pdf_url":null,"source":{"id":"https://openalex.org/S2764493120","display_name":"JMIR mhealth and uhealth","issn_l":"2291-5222","issn":["2291-5222"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1163551930","https://openalex.org/W2108771604","https://openalex.org/W2149564130","https://openalex.org/W2155686324","https://openalex.org/W2155827104","https://openalex.org/W2418120401","https://openalex.org/W2471262782","https://openalex.org/W2563158481","https://openalex.org/W2569460261","https://openalex.org/W2584941439","https://openalex.org/W2621741324","https://openalex.org/W2883177470","https://openalex.org/W3008659445","https://openalex.org/W3107250066","https://openalex.org/W3185598629","https://openalex.org/W4247055947","https://openalex.org/W4283720279","https://openalex.org/W4286435228","https://openalex.org/W4308045527","https://openalex.org/W4406431707"],"related_works":["https://openalex.org/W4308045527","https://openalex.org/W6902108470","https://openalex.org/W4367626552","https://openalex.org/W3136032410","https://openalex.org/W3128236677","https://openalex.org/W4403368268","https://openalex.org/W4410441864","https://openalex.org/W4405040037","https://openalex.org/W2922218158","https://openalex.org/W7223370717"],"abstract_inverted_index":{"BACKGROUND:":[0],"Frailty":[1],"is":[2,17,29],"highly":[3],"prevalent":[4],"in":[5,60,86,187,284,319,341,380,388],"survivors":[6,87,389],"of":[7,73,88,144,147,158,175,231,241,251,390],"multiple":[8],"myeloma":[9],"(MM)":[10],"after":[11,93,393],"autologous":[12,94,394],"hematopoietic":[13,95],"cell":[14,96],"transplantation":[15],"and":[16,23,83,137,208,236,266,310,334,348,378,384,416],"associated":[18],"with":[19,179,288,324,326],"poor":[20],"functional":[21,386],"recovery":[22,409],"adverse":[24,363],"clinical":[25],"outcomes.":[26],"Although":[27],"exercise":[28,52,77,118,161,277,305,321,353,372],"known":[30],"to":[31,42,69,115,219,258,292],"improve":[32],"physical":[33,84],"function,":[34],"traditional":[35],"center-based":[36],"rehabilitation":[37,78,373,405],"models":[38],"are":[39,419],"often":[40],"inaccessible":[41],"this":[43,100],"population":[44],"during":[45,268,406],"early":[46,392],"posttransplant":[47],"recovery.":[48],"Mobile":[49],"health":[50],"(mHealth)-supported":[51],"may":[53],"offer":[54],"a":[55,74,172,228,239,280,300,399,407],"scalable":[56,400],"alternative;":[57],"however,":[58],"evidence":[59],"hematologic":[61],"malignancies":[62],"remains":[63],"limited.":[64],"OBJECTIVE:":[65],"This":[66,396],"study":[67],"aimed":[68],"evaluate":[70,220],"the":[71,163,188,259,269,320,352],"effects":[72],"16-week":[75,368],"mHealth-supported":[76,117],"program":[79,374],"on":[80],"frailty":[81,191,285,382],"phenotype":[82,192,383],"function":[85],"MM":[89,391],"within":[90],"180":[91],"days":[92,245],"transplantation.":[97,395],"METHODS:":[98],"In":[99],"single-center":[101],"randomized":[102,113],"controlled":[103],"trial,":[104],"participants":[105,252],"who":[106],"self-reported":[107],"as":[108,255],"prefrail":[109],"or":[110,121],"frail":[111],"were":[112,128,213,237,253],"1:1":[114],"an":[116],"group":[119,278,322,354],"(n=16)":[120],"usual":[122],"care":[123],"control":[124,289],"(n=16).":[125],"Remote":[126],"assessments":[127],"conducted":[129,214],"at":[130,306,331],"baseline":[131,291],"(week":[132,135,139],"0),":[133],"midpoint":[134],"9),":[136],"follow-up":[138,418],"17).":[140],"The":[141,182,276],"intervention":[142],"consisted":[143],"8":[145,156],"weeks":[146,157],"supervised":[148,260],"tele-exercise":[149],"(3":[150],"sessions/week,":[151],"50":[152],"minutes/session),":[153],"followed":[154],"by":[155],"independent":[159],"home-based":[160],"using":[162,171,215],"same":[164],"mHealth":[165],"platform.":[166],"Exercise":[167],"intensity":[168],"was":[169,185,262,272,375],"prescribed":[170,371],"repetitions-in-reserve-based":[173],"rating":[174],"perceived":[176],"exertion":[177],"approach":[178,397],"symptom-guided":[180],"progression.":[181],"primary":[183],"outcome":[184],"change":[186],"5-component":[189],"Fried":[190],"score":[193,286],"(0-5).":[194],"Secondary":[195],"outcomes":[196],"included":[197],"Short":[198,343],"Physical":[199,344],"Performance":[200,345],"Battery":[201,346],"components,":[202],"chair":[203],"stand":[204,315],"time,":[205],"gait":[206],"speed,":[207],"handgrip":[209,349],"strength.":[210],"Intention-to-treat":[211],"analyses":[212],"generalized":[216],"estimating":[217],"equations":[218],"between-group":[221],"differences":[222],"over":[223],"time.":[224],"RESULTS:":[225],"Participants":[226],"had":[227],"mean":[229,240],"age":[230],"64.6":[232],"(SD":[233,243],"7.1)":[234],"years":[235],"enrolled":[238],"136":[242],"36.3)":[244],"posttransplant.":[246],"At":[247],"baseline,":[248],"94%":[249],"(30/32)":[250],"classified":[254],"frail.":[256],"Adherence":[257],"sessions":[261],"85%":[263],"(326/384":[264],"sessions),":[265],"adherence":[267],"unsupervised":[270],"phase":[271],"78%":[273],"(298/384":[274],"sessions).":[275],"demonstrated":[279],"significantly":[281,318],"greater":[282],"reduction":[283],"compared":[287,323],"from":[290],"week":[293,308,311,332,337],"17":[294,312,338],"(P<.001).":[295,313],"Between-group":[296],"difference":[297],"estimates":[298],"showed":[299],"clinically":[301],"meaningful":[302],"improvement":[303],"favoring":[304],"both":[307],"9":[309,333],"Chair":[314],"time":[316],"improved":[317],"control,":[325],"faster":[327],"completion":[328],"times":[329],"observed":[330],"sustained":[335],"through":[336],"(P=.002).":[339],"Improvements":[340],"other":[342],"components":[347],"strength":[350],"favored":[351],"but":[355],"did":[356],"not":[357],"reach":[358],"statistical":[359],"significance.":[360],"No":[361],"serious":[362],"events":[364],"occurred.":[365],"CONCLUSIONS:":[366],"A":[367],"mHealth-supported,":[369],"progressively":[370],"feasible,":[376],"safe,":[377],"effective":[379],"reversing":[381],"improving":[385],"mobility":[387],"provides":[398],"model":[401],"for":[402],"delivering":[403],"structured":[404],"high-risk":[408],"window.":[410],"Larger":[411],"trials":[412],"incorporating":[413],"attention-matched":[414],"controls":[415],"longer":[417],"warranted.":[420],"TRIAL":[421],"REGISTRATION:":[422],"ClinicalTrials.gov":[423],"NCT05142371;":[424],"https://clinicaltrials.gov/study/NCT05142371.":[425]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-04-03T00:00:00"}